Abstract：
:There has been a long, unresolved debate regarding the operation of choice for well differentiated carcinoma of the thyroid. We therefore analyzed the feasibility, scope, sample size, and length of follow-up required to determine the optimal operation for papillary thyroid carcinoma. A statistical approach was used to design a randomized prospective trial comparing the endpoints of complications, recurrence, and cause-specific mortality. A complication comparison trial is prohibitive owing to the large population required--approximately 12,000 randomized patients. A recurrence trial appears feasible based on sample size: approximately 360 to 800 patients with a 6 to 10-year follow-up. However, recurrence detection would be severely compromised in the lobectomy arm, and a unilateral lag-time bias would occur. A cause-specific mortality trial proves to be the least objectionable, although a large sample size (n = 3100) would be required. Such a trial is critically dependent on the ability to select an appropriate endpoint. A cause-specific mortality trial proves to be the most objective and statistically valid endpoint.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Udelsman R,Lakatos E,Ladenson Pdoi
10.1007/s002689900016subject
Has Abstractpub_date
1996-01-01 00:00:00pages
88-93issue
1eissn
0364-2313issn
1432-2323journal_volume
20pub_type
杂志文章,评审abstract：BACKGROUND:The most important problem in pancreatic fistula is whether one can distinguish clinical pancreatic fistula, grade B + C fistula by the International Study Group on Pancreatic Fistula (ISGPF), from transient pancreatic fistula (grade A), in the early period after pancreaticoduodenectomy (PD). It remains uncl...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0220-2
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:LLR is widely adapted for HCC, while LLR in PS segments is still challenging. With recent improvement of techniques and accumulation of experiences, LLR in PS segments is feasible, but studies investigating the result after the modifications are lacking. METHODS:In this single-center, retrospective study, 1...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05912-5
更新日期：2021-01-13 00:00:00
abstract：:Experience with the use of nylon fishing line for surgical sutures has been reported from several African countries. A recent publication suggested that fishing line and an injection needle may provide an atraumatic suture that is especially suitable for intracutaneous skin closures. This article provides further empi...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00268-003-7323-y
更新日期：2004-04-01 00:00:00
abstract：:This study aimed (1) to develop a simple scoring system incorporating ultrasound (US) examination and clinical or laboratory predictors for increasing diagnostic accuracy in acute appendicitis (AA), and (2) to evaluate the performance of the scoring system as compared to that of previous models. Fifteen variables incl...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-7853-6
更新日期：2005-09-01 00:00:00
abstract：BACKGROUND AND AIMS:A variety of minimally invasive techniques have been proposed to replace open surgery for the treatment of infected pancreatic necrosis (IPN). In this study, we evaluate the feasibility and safety of the stent-assisted percutaneous endoscopic necrosectomy (SAPEN) procedure. METHODS:Data were collec...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-04878-9
更新日期：2019-04-01 00:00:00
abstract：:A semiquantitative assessment of multiple histological parameters was applied retrospectively to 66 patients with stage I and II squamous cell carcinoma of the floor of the mouth to determine if prognostic information relative to cervical node metastases could be obtained. Three parameters relating to the tumor cell p...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01658802
更新日期：1990-09-01 00:00:00
abstract：:Met protein is a tyrosine kinase receptor for hepatocyte growth factor (HGF). c-Met has morphogenic, mitogenic, and motogenic properties and is overexpressed in many solid tumors. We studied c-met mRNA and protein expression in papillary thyroid carcinomas and nonneoplastic thyroid tissue. The c-met mRNA was detected ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002680020167
更新日期：2001-05-01 00:00:00
abstract：:Two-hundred and fifty patients undergoing initial exploration for primary hyperparathyroidism were analyzed for differences in clinical presentation, biochemical status, pathology, and outcome of surgery. In patients less than 60 years of age (younger patients, n = 119) the most common preoperative symptoms and signs ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF02067389
更新日期：1992-07-01 00:00:00
abstract：BACKGROUND:Organ shortage is the greatest challenge facing the field of organ transplantation today. Use of more organs of marginal quality has been advocated to address the shortage. METHOD:We examined the pattern of donation and organ use in the United States as shown in the Organ Procurement and Transplantation Net...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1748-0
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:Frequent use of computed tomography (CT) in trauma patients results in frequent detection of non-trauma-related incidental findings (IFs). Inpatient documentation and disclosure at discharge are infrequent, even when they are potentially serious. We aimed to not only identify the incidence of IFs but also to...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2092-8
更新日期：2013-09-01 00:00:00
abstract：:The development of laparoscopic surgery has provided minimally invasive surgeons with advanced laparoscopic instrumentation and high definition imaging. The resulting surgical expertise and technology has now been extended to gastric endoluminal surgery. Laboratory and clinical investigations have been initiated for v...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/pl00012311
更新日期：1999-04-01 00:00:00
abstract：AIM:To evaluate the application value of a three-dimensional (3D) printing model in the training of choledochoscopy techniques. MATERIALS AND METHODS:Imaging data from two patients with biliary dilatation were used to produce two 3D reconstruction models which were subsequently constructed into 3D printing models (No....
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-018-4731-6
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Gastroesophageal reflux is the main risk factor for esophageal adenocarcinoma, but there is no strong support for a protective effect of antireflux surgery. We tested the hypothesis that esophageal adenocarcinoma that develops with long latency after antireflux surgery might be due to persistent postoperativ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-006-0386-9
更新日期：2007-03-01 00:00:00
abstract：BACKGROUND:The postoperative functional advantages of a proximal gastrectomy over a total gastrectomy remain debatable. The aim of this study was to evaluate the functional outcomes of a proximal gastrectomy with jejunal interposition (PG-JI), compared with those for a total gastrectomy with Roux-en-Y esophagojejunosto...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3180-8
更新日期：2015-11-01 00:00:00
abstract：:Although a number of histologic and treatment factors that individually and in combination predict for an increased risk of local recurrence after breast conserving surgery can be identified, none so obviously compromises survival that breast conservation is contraindicated because that risk factor is present. In-brea...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF00348195
更新日期：1994-01-01 00:00:00
abstract：INTRODUCTION:Hypoxic stress is a feature of rapidly growing thyroid tumours. Cancer progression is thought to be driven by a small population of tumour cells possessing stem cell properties. Hypoxia-inducible factors (HIFs) are important mediators of hypoxia. Both HIF-1alpha and HIF-2alpha have been reported to be expr...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4331-x
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:The survival impact of distal pancreatectomy (DP) with celiac axis resection for locally advanced pancreatic body/tail cancer remains unclear. METHODS:A total of 16 patients underwent DP with celiac axis resection, while 76 underwent standard DP for pancreatic body/tail cancer. The indications for DP with c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3670-3
更新日期：2017-01-01 00:00:00
abstract：:Studies have recorded significant patient discomfort during flexible sigmoidoscopy when it is performed without sedation/analgesia. This study observed whether a single dose of 50 mcg intravenous fentanyl reduces pain, improving compliance, acceptability, and completion rates. In a prospective study, 109 consecutive p...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s00268-004-7374-8
更新日期：2004-09-01 00:00:00
abstract：BACKGROUND:The adoption of robotic systems for gastric cancer surgery has been proven feasible and safe; however, a benefit over the laparoscopic approach has not yet been well-documented. We aimed to investigate the surgical outcomes of robotic versus laparoscopic gastrectomy for gastric cancer, according to the exten...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-2998-4
更新日期：2015-07-01 00:00:00
abstract：BACKGROUND:Critical illness disproportionately affects people in low-income countries (LICs). Efforts to improve critical care in LICs must account for differences in demographics and infrastructure compared to high-income settings. Part of this effort includes the development and validation of intensive care unit (ICU...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05078-9
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:Stapled anopexia was introduced as a surgical method in 1993. Long-term data with special interest in functional results and relapse symptoms are rarely presented. Urinary discomfort and problems with fecal urge incontinence are addressed as severe side effects. We present our long-term results (using data f...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9818-z
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:Finnmark County is the northernmost county in Norway. For several decades, the rate of mortality after injury in this sparsely inhabited region has remained above the national average. Following documentation of this discrepancy for the period 1991-1995, improvements to the trauma system were implemented. Th...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1102-y
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND:The pancreatic fistula rate following distal pancreatectomy ranges widely, from 13.3 to 64.0 %. The optimal closure method of the pancreatic remnant remains controversial, especially regarding whether to use a stapler. METHODS:All patients who underwent distal pancreatectomy in five Japanese hospitals from ...
journal_title：World journal of surgery
pub_type： 杂志文章,多中心研究
doi：10.1007/s00268-012-1595-z
更新日期：2012-08-01 00:00:00
abstract：:The measurement of the burden of disease and the interventions that address that burden can be done in various units. Reducing these measures to the common denominator of economic units (i.e., currency) enables comparison with other health entities, interventions, and even other fields. Economic assessment is complex,...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1796-5
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:The open abdomen (OA) is commonly utilized as a technique during damage control laparotomy (DCL). We propose that a selected group of these OA patients can be extubated prior to abdominal closure to decrease ventilator days and risk of pneumonia. METHODS:A retrospective chart review was performed at a Level...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4610-1
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Laparoscopic resection of posterosuperior (PS) tumors of the liver is more difficult than that of anterolateral (AL) tumors, owing to the narrow surgical field in the PS location. In this retrospective cohort study, our aim was to determine if port insertion through the intercostal space would lead to improv...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3867-5
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:To evaluate whether the preoperative magnetic resonance angiography (MRA) can predict the risk of cerebral ischemia associated with the carotid endarterectomy (CEA). METHODS:Between January 2004 and December 2010, 382 consecutive patients (mean age: 56.6 years; range: 45-78 years) were identified to have un...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1851-2
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:Laparoscopic rectal resection (LRR) for cancer is a challenging procedure, with conversion to open surgery being reported in up to 30% of cases. Since only a few studies with short follow-up have compared converted LRR and open RR (ORR), it is unclear if conversion to open surgery should be prevented by pref...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4614-x
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Right hepatectomy with caudate lobectomy (RHx) is considered an appropriate procedure for Bismuth type I/II perihilar cholangiocarcinoma in terms of its anatomical and oncological aspect. However, validity of left hepatectomy with caudate lobectomy (LHx) concomitant with arterial resection and reconstruction...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4833-1
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:The psychiatric population has been reported to be accompanied with a higher morbidity and mortality in several situations. However, little is known about the effect of co-morbid psychiatric disorders on surgical risk during major digestive surgery for malignancies. Our purpose in the present study, therefor...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9267-0
更新日期：2007-12-01 00:00:00
