Abstract：
BACKGROUND:Seroma formation is a frequent postoperative complication following open ventral hernia repair (OVHR), especially in cases requiring wide subcutaneous dissection (WSD). The aim of this study was to evaluate the effectiveness of a new low-thrombin fibrin sealant for seroma prevention. METHODS:A total of 60 consecutive patients with median incisional hernias who required OVHR with WSD of at least 100 cm(2) were included in the prospective non-randomized study. The fibrin glue group (FG) comprised 30 patients who had undergone OVHR with sublay mesh placement as well as subcutaneous application of low-thrombin fibrin sealant. This cohort of patients was compared with a control group (CG) of 30 consecutive patients who had previously undergone OVHR without prevention of seroma formation with regard to outcome measures such as seroma formations and wound complications. RESULTS:Though the median extent of subcutaneous dead space was larger in the FG than in the CG (229 vs.174 cm(2); p = 0.012), seroma formation occurred in three of the FG versus 16 of the CG patients (p = 0.003). Postoperative wound complications occurred in two of the FG versus nine of the CG patients (p = 0.002). Four patients in the CG and none in the FG required re-operation within 30 days (p < 0.001). CONCLUSION:The use of a new low-thrombin fibrin glue demonstrated a protective effect against formation of seromas and decreased the rate of wound complications in OVHR, with consecutive shorter length of hospital stay (5.8 vs. 10.4 days; p = 0.04).
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Köhler G,Koch OO,Antoniou SA,Lechner M,Mayer F,Emmanuel Kdoi
10.1007/s00268-014-2691-zsubject
Has Abstractpub_date
2014-11-01 00:00:00pages
2797-803issue
11eissn
0364-2313issn
1432-2323journal_volume
38pub_type
杂志文章abstract：:Local recurrence in differentiated and medullary thyroid carcinoma develops frequently from metastatic infiltration of cervical lymph nodes. Despite an aggressive surgical approach, postoperative calcitonin levels as biochemical evidence for residual cancer cells remain often elevated in patients with medullary thyroi...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0197-y
更新日期：2002-02-01 00:00:00
abstract：:A wide range of clinical symptoms and signs are observed with venous thrombosis. Nonetheless, clinical diagnosis has been found to be unreliable and accurate diagnostic methods must be used before potent therapy such as anticoagulation is instituted, since the complications of treatment themselves can be life-threaten...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01658825
更新日期：1990-09-01 00:00:00
abstract：:Childhood papillary thyroid carcinoma is associated with more locally aggressive and more frequent distant disease than its adult counterpart. Recurrence rates tend to be higher in children, but cause-specific mortality remains low. Optimal initial treatment of childhood papillary thyroid carcinoma should include tota...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-004-7605-z
更新日期：2004-12-01 00:00:00
abstract：:The geographic distribution of duodenal ulcer and its characteristics in rural areas of high incidence in developing countries are reviewed. The choice of surgical procedures is discussed in light of the bulky diet and nutritional problems of these countries. A vagotomy procedure is advised for duodenal ulcer and a B...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01654731
更新日期：1977-01-01 00:00:00
abstract：:The aim of this study was to investigate the epidemiologic characteristics and changing patterns of gallstone disease in Korea over a recent 20-year period. A total of 4020 gallstone patients who had undergone surgery at Seoul National University Hospital during 1981-2000 were analyzed according to periods: period I (...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-6879-x
更新日期：2004-02-01 00:00:00
abstract：BACKGROUND:Recurrent laryngeal nerve palsy (RLNP) is one of the most common complications after thyroidectomy. We aim to evaluate the role of intraoperative corticosteroids in preventing or treating postoperative RLNP. MATERIALS AND METHODS:We conducted a prospective study of 295 patients who underwent either total lo...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0399-9
更新日期：2006-03-01 00:00:00
abstract：BACKGROUND:The purpose of the present study was twofold: to summarize the characteristics of trauma patients with thoracic injury in the 2008 earthquake of Wenchuan, Sichuan, China, and to validate the accuracy of the Injury Severity Score (ISS), the New Injury Severity Score (NISS), and the Chest Injury Index (CII) in...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0427-2
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:Self-expanding metallic stents (SEMS) have been used as a bridge to surgery in patients with obstruction by colorectal cancer, but the oncologic safety of this technique has not yet been established. The aim of the present study was to compare the outcomes of bridge to surgery after SEMS insertion and nonobs...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0007-5
更新日期：2009-06-01 00:00:00
abstract：INTRODUCTION:The coexistence of an enterocutaneous fistula (ECF) with large abdominal wall defects represent one of the most demanding situations seen by a surgeon. Simultaneous treatment of ECF closure with abdominal wall defect closure has been widely debated. Our objective was to determine if the type of abdominal w...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05635-7
更新日期：2020-10-01 00:00:00
abstract：:Factors influencing postoperative hospital mortality and long-term survival after radical resection of stage IV gallbladder carcinoma remain unclear. The objective of this study was to identify characteristics of patients who are good candidates in terms of surgical risk and long-term survival for radical resection of...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6654-4
更新日期：2003-03-01 00:00:00
abstract：BACKGROUND:The Lancet recently sponsored a commission examining the role of surgery in global health. There is a paucity of published information on the cost-effectiveness of surgery in low- and middle-income countries, a key metric in the prioritisation of limited resources. METHODS:All patients undergoing emergency ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3271-6
更新日期：2016-01-01 00:00:00
abstract：:Bacterial biofilms develop on a number of living and inert surfaces within the urinary tract, producing chronic intractable infections. The role of exopolysaccharides in producing a variety of extracellular polymeric substances according to the infection site and bacterial species and the clinical features of the resu...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002680010203
更新日期：2000-10-01 00:00:00
abstract：BACKGROUND:The albumin-bilirubin (ALBI) score was initially developed for assessing liver dysfunction severity and was suggested to have prognostic value in patients with hepatocellular carcinoma. We aimed to evaluate the prognostic impact of ALBI grade in patients with advanced gastric cancer (GC) after radical gastre...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4234-x
更新日期：2018-03-01 00:00:00
abstract：BACKGROUND:Screening of multiple endocrine neoplasia type 1 (MEN-1) patients is widely recommended because one-fifth succumb to malignant neoplasms. However, recommendations for screening modalities and intervals are based mostly on nonprospective data. METHODS:Thirty-five of 48 MEN-1 patients were evaluated at least ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-9983-8
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND:Accurate, complete and sustainable methods of tracking patients and outcomes in low-resource settings are imperative as we launch efforts to improve surgical care globally. The Surgical services QUality Assessment Database (SQUAD) at the Mbarara Regional Referral Hospital in Uganda is one of very few electro...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4172-7
更新日期：2018-01-01 00:00:00
abstract：:We retrospectively reviewed postoperative complications in 105 patients with hilar cholangiocarcinoma who underwent hepatectomy at Nagoya University Hospital from January 1990 through March 1999. Of the 105 subjects, 97 (92.4%) underwent resection of two or more Healey's segments of the liver. Combined portal vein res...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0110-8
更新日期：2001-10-01 00:00:00
abstract：BACKGROUND:The new global epidemic, overweight and obesity, has a significant role in the etiology of liver tumors. However, the impact of body weight on the outcome after liver resection is unknown. METHODS:We carried out a prospective study of 684 patients who underwent liver resections. Patients were stratified acc...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0756-1
更新日期：2010-12-01 00:00:00
abstract：:Despite a slow decline in the incidence of gastric cancer over the last 90 years, we can still expect to see over 100,000 patients die of this disease each decade in England and Wales. The 5-year survival rate has not improved during this century, which is largely due to the stage at diagnosis being unchanged. There a...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF00294709
更新日期：1995-07-01 00:00:00
abstract：BACKGROUND:Esophagorespiratory fistula (ERF) caused by esophageal carcinoma is a fatal complication. In our institution, esophageal bypass surgery has been indicated when possible. We herein retrospectively describe the clinical results of esophageal bypass surgery for ERF. PATIENTS AND METHODS:Between April 2001 and ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3391-z
更新日期：2016-05-01 00:00:00
abstract：BACKGROUND:We aimed to systematically review the literature on the educational impact of Advanced Trauma Life Support (ATLS) courses and their effects on death rates of multiple trauma patients. METHODS:All Medline, Pubmed, and the Cochrane Library English articles on the educational impact of ATLS courses and their e...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-013-2294-0
更新日期：2014-02-01 00:00:00
abstract：:Central pancreatectomy is an uncommonly performed procedure that may be particularly useful for the removal of benign and low malignant potential lesions in the neck and body of the pancreas. This procedure may have fewer major complications and better preserve endocrine and exocrine function than the more commonly pe...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-6848-4
更新日期：2003-05-01 00:00:00
abstract：BACKGROUND:The goal of the present study was to critically review and identify the strength of available evidence in the literature on the use of laparoscopic appendectomy (LA) in complicated appendicitis (CA). METHODS:The Cochrane Library and Controlled Trials Registry, MEDLINE (Ovid), PubMed, Web of knowledge, and S...
journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00268-010-0669-z
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:The aim of this trial was to compare the Enhanced Recovery After Surgery (ERAS) program with conventional perioperative management in patients who underwent radical resection for colorectal cancer. METHODS:A combination of evidence-based and consensus methodology was used to develop the ERAS protocol. Five ...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-011-1348-4
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:Surgical resection remains the treatment of choice for carotid body tumors (CBTs). Although perioperative complications such as carotid artery injury and neurological deficits occur infrequently, they can be devastating. The aim of this study was to evaluate whether clinical factors or preoperative imaging f...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3058-9
更新日期：2015-08-01 00:00:00
abstract：:Breast cancer is a common disease, and the surgical management is continually evolving. The objective of this study was to describe the current breast cancer practice patterns among Canadian surgeons. All active General Surgeons (n=1172), as accredited by the Royal College of Physicians and Surgeons of Canada, were se...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7040-6
更新日期：2004-01-01 00:00:00
abstract：BACKGROUND:Artificial intelligence is touted as the future of medicine. Classical algorithms for the detection of common bile duct stones (CBD) have had poor clinical uptake due to low accuracy. This study explores the challenges of developing and implementing a machine-learning model for the prediction of CBD stones i...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05820-8
更新日期：2021-02-01 00:00:00
abstract：BACKGROUND:Surgical 'never events' have serious adverse outcomes for patients. A never event can be defined as a serious, avoidable patient safety incident that would not occur if necessary preventative measures are implemented. The literature from South Africa on this topic is limited. This study aims to understand th...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05008-9
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:Currently, most patients undergoing laparoscopic cholecystectomy (LC) in Switzerland are inpatients for 2-3 days. Due to a lack of available hospital beds, we asked whether day-case surgery would be an option for patients in central Switzerland. The questions of acceptability of outpatient LC and factors con...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4098-0
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:The aim of the study was to compare the changes in health-related quality of life (QOL) after lung surgery between young and old patients. METHODS:We performed a prospective, population-based, cohort study to investigate health-related QOL before and 6 months after lung surgery. We used the validated instru...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0430-7
更新日期：2010-04-01 00:00:00
abstract：INTRODUCTION:The past 25 years have been witness to a revolution in how vascular care is delivered. The majority of arterial and venous interventions have converted from open surgery to minimally invasive percutaneous endovascular procedures. METHODS:This surgical innovations symposium article reviews current endovasc...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05875-7
更新日期：2020-11-22 00:00:00
