Diagnosis of deep vein thrombosis.

Abstract:

:A wide range of clinical symptoms and signs are observed with venous thrombosis. Nonetheless, clinical diagnosis has been found to be unreliable and accurate diagnostic methods must be used before potent therapy such as anticoagulation is instituted, since the complications of treatment themselves can be life-threatening. Phlebography is still the basic reference for evaluation of deep venous disease. While it is felt to be the most accurate, there are still limitations relative to difficulty in separating acute from chronic disease, and in obtaining adequate contrast in certain veins such as calf muscles and in the larger intraabdominal veins. Moreover, it is an uncomfortable invasive test, not without complications of its own. The 125I-fibrinogen uptake test is an excellent test for screening for forming thrombi. The sensitivity of this test is high, particularly in the detection of small calf vein thrombi. The primary drawbacks of this technique are that it is falsely positive in cases where there has been bleeding, inflammation, gross edema, arthritis, or leg ulceration. It is not accurate above mid-thigh because of the high blood flow at the level of the groin and pelvis. Radioactive labeled plasmin which will adhere to the surface of recently formed thrombi can also be used for diagnosis. The limitations are a very short half-life of the radioactive label so that repeated investigation of a patient cannot be performed unless new injections are given. The diagnostic accuracy is comparable to that of radioactive labeled fibrinogen and has the same advantages and disadvantages. Plethysmographic techniques have been used with various modifications.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

World J Surg

journal_title

World journal of surgery

authors

Bergqvist D,Bergentz SE

doi

10.1007/BF01658825

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

679-87

issue

5

eissn

0364-2313

issn

1432-2323

journal_volume

14

pub_type

杂志文章,评审
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  • Laparoscopic intragastric full-thickness excision (LIFE) of posterior gastric lesions under flexible endoscopic control--a feasibility study.

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    journal_title:World journal of surgery

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  • Comprehensive Complication Index or Clavien-Dindo Classification: Which is Better for Evaluating the Severity of Postoperative Complications Following Pancreatectomy?

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  • The Mangled Extremity Severity Score Fails to be a Good Predictor for Secondary Limb Amputation After Trauma with Vascular Injury in Central Europe.

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    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/BF01658439

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  • Adenocarcinoma of distal esophagus and gastroesophageal junction: long-term results of surgical treatment in a North Indian Center.

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  • Liver Resection for Hepatocellular Carcinoma in Patients with Renal Dysfunction.

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    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-007-9321-y

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    更新日期:2008-04-01 00:00:00

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    pub_type: 杂志文章

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    authors: Zhang HY,Li WB,Ye H,Xiao ZY,Peng YR,Wang J

    更新日期:2014-08-01 00:00:00

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    journal_title:World journal of surgery

    pub_type: 杂志文章

    doi:10.1007/s00268-014-2579-y

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    更新日期:2014-09-01 00:00:00

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    pub_type: 临床试验,杂志文章

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    pub_type: 杂志文章

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  • Acute Care Surgery Models Worldwide: A Systematic Review.

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