Analytical models of atherosclerosis.

abstract：BACKGROUND AND AIMS:Cardiovascular disease (CVD) and cancer are the two leading causes of death in smokers. Lung cancer screening is recommended in a large proportion of smokers. We examined the implication of coronary artery calcium (CAC) score (quantitative and qualitative) for cardiovascular disease (CVD), coronary ...

journal_title：Atherosclerosis

authors： Mirbolouk M,Kianoush S,Dardari Z,Miedema MD,Shaw LJ,Rumberger JA,Berman DS,Budoff MJ,Rozanski A,Al-Mallah MH,McEvoy JW,Nasir K,Blaha MJ

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND/AIM:In type 2 diabetes and other insulin-resistant conditions, postprandial hypertriglyceridaemia is an important metabolic perturbation. To further elucidate alterations in the clearance of triglyceride-rich lipoproteins in type 2 diabetes we focused on the nutritional regulation of adipose tissue lipoprote...

journal_title：Atherosclerosis

authors： Eriksson JW,Burén J,Svensson M,Olivecrona T,Olivecrona G

更新日期：2003-02-01 00:00:00

abstract：:This review evaluates novel beneficial effects of circulating endothelial progenitor cells (EPCs) as shown by several preclinical studies and clinical trials carried out to test the safety and feasibility of using EPCs. There are 31 registered clinical trials (and many others still ongoing) and 19 published studies. E...

journal_title：Atherosclerosis

authors： Napoli C,Hayashi T,Cacciatore F,Casamassimi A,Casini C,Al-Omran M,Ignarro LJ

更新日期：2011-03-01 00:00:00

abstract：:In symptom-free subjects, exercise tolerance testing (ETT) has a doubtful utility for detecting latent coronary heart disease (CHD) because of frequent false positives, but it may be valuable for predicting future CHD. To clarify the latter question, we calculated CHD incidence associated with presence or absence of E...

journal_title：Atherosclerosis

authors： Mégnien JL,Simon A

更新日期：2009-08-01 00:00:00

abstract：:HDL has been shown to enhance the removal of cholesterol from cultured fibroblasts, smooth muscle cells and macrophages, but fails to stimulate cholesterol removal from J-774 macrophages. Since J-774 macrophages do not synthesize or secrete apolipoprotein E, the effect of exogenous apolipoprotein E on HDL-mediated cel...

journal_title：Atherosclerosis

authors： Granot E,Eisenberg S

更新日期：1995-04-07 00:00:00

abstract：:The aim of the present study was to investigate plasma levels of asymmetric dimethylarginine (ADMA), an important endogenous inhibitor of nitric oxide synthase, in populations at high risk for atherosclerosis as compared to healthy controls, and furthermore to evaluate the effect of cholesterol lowering therapy in ind...

journal_title：Atherosclerosis

authors： Eid HM,Eritsland J,Larsen J,Arnesen H,Seljeflot I

更新日期：2003-02-01 00:00:00

abstract：:Research has indicated that inflammation promote all phases of atherosclerosis. The current study tested the hypothesis that rhinosinusitis is a risk marker for myocardial infarction (MI). Data on the general population were obtained from the Taiwan Longitudinal Health Insurance Database 2005 (LHID2005). The study coh...

journal_title：Atherosclerosis

authors： Hao WR,Lin HW,Chao PZ,Wu CW,Yen TH,Liu JC,Liou TH

更新日期：2013-01-01 00:00:00

abstract：:Thrombomodulin, an endothelial membrane glycoprotein, is an essential part of the protein C anti-coagulant pathway. It may also have a role in the regulation of fibrinolysis. We carried out a cross-sectional study to assess the association of soluble thrombomodulin (sTM) with peripheral artery disease (PAD) in a strat...

journal_title：Atherosclerosis

authors： Salomaa V,Matei C,Aleksic N,Sansores-Garcia L,Folsom AR,Juneja H,Park E,Wu KK

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:To evaluate the impact of familial hypercholesterolemia (FH) and familial combined hyperlipidemia (FCH) on arterial properties and the effects of statins. METHODS:We meta-analyzed 51 studies providing data for 4,057 FH patients and 732 FCH patients with random-effects models, meta-regression analysis and pu...

journal_title：Atherosclerosis

authors： Masoura C,Pitsavos C,Aznaouridis K,Skoumas I,Vlachopoulos C,Stefanadis C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Left-sided valvular calcification is associated with cardiovascular disease (CVD) morbidity and mortality. Resting heart rate (RHR) may influence valvular calcium progression through shear stress. Whether RHR, an established CVD risk factor, is associated with valvular calcium progression is unknown...

journal_title：Atherosclerosis

authors： Amoakwa K,Fashanu OE,Tibuakuu M,Zhao D,Guallar E,Whelton SP,O'Neal WT,Post WS,Budoff MJ,Michos ED

更新日期：2018-06-01 00:00:00

abstract：:AMO 1618 (2-isopropyl-4-dimethylamino-5-methylphenyl-1-piperidine carboxylate methyl chloride) was added to corn-soy based diets and fed to 9-week-old female chickens for 3 weeks to measure the inhibition of hepatic beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase and cholesterol 7 alpha-hydroxylase. Do...

journal_title：Atherosclerosis

authors： Qureshi AA,Abuirmeileh N,Burger WC,Din ZZ,Elson CE

更新日期：1983-02-01 00:00:00

abstract：:Consecutive patients (n=964) undergoing coronary angiography were studied and compared with a random population sample regarding serum lipids and lipoproteins with focus on lipoprotein(a) (Lp[a]) levels and apo(a) isoforms. The patients were also followed for 5 years after the angiography, and the prognostic value of ...

journal_title：Atherosclerosis

authors： Lindén T,Taddei-Peters W,Wilhelmsen L,Herlitz J,Karlsson T,Ullström C,Wiklund O

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:Antiphospholipid antibodies are associated with increased risk of thrombosis, particularly as in antiphospholipid syndrome. This study aims to determine the acute effects of anticardiolipin antibodies on nitric oxide production and vascular function. METHODS:Ex vivo aortic rings from male Sprague Dawley rats...

journal_title：Atherosclerosis

authors： Alves JD,Clapp BR,Stidwill R,Chen PP,Hingorani AD,Singer M,Isenberg DA

更新日期：2006-04-01 00:00:00

abstract：:The newly identified apoprotein AV (apoAV) gene was suggested to have a significant effect on triglyceride (TG) metabolism in Caucasians. We studied the genetic effect of this gene on serum TG in a Japanese population. Participants (481 male and 412 female) were recruited at a health examination. A T/C single nucleoti...

journal_title：Atherosclerosis

authors： Nabika T,Nasreen S,Kobayashi S,Masuda J

更新日期：2002-12-01 00:00:00

abstract：INTRODUCTION:Although cardiovascular events are known to cluster in families it is unclear the extent to which atherosclerosis per se is genetically determined. The aim of this study was to assess the heritability of carotid intima media thickness (IMT) measurements, a surrogate marker of early atherosclerosis, using a...

journal_title：Atherosclerosis

authors： Swan L,Birnie DH,Inglis G,Connell JM,Hillis WS

更新日期：2003-01-01 00:00:00

abstract：:Five out of 15 homozygotes and 41 out of 527 heterozygotes of familial hypercholesterolemia (FH) died during the past 10 years. Sudden death or heart failure was the cause of death in each of the 5 deceased homozygotes. Twenty heterozygotes died of myocardial infarction, 9 of sudden death, and 1 died after AC bypass s...

journal_title：Atherosclerosis

authors： Mabuchi H,Miyamoto S,Ueda K,Oota M,Takegoshi T,Wakasugi T,Takeda R

更新日期：1986-07-01 00:00:00

abstract：:We investigated the possibility that established atherosclerosis and xanthomas in mature WHHL rabbits could be suppressed or even regressed when their serum cholesterol levels were kept extremely low. Ten-month-old WHHL rabbits were divided into 3 groups, i.e. control rabbits, sacrificed at age 10 months, and placebo ...

journal_title：Atherosclerosis

authors： Shiomi M,Ito T,Watanabe Y,Tsujita Y,Kuroda M,Arai M,Fukami M,Fukushige J,Tamura A

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVE:The benefits of fish oil fatty acids eicosapentaenoic (EPA) and docosahexaenoic acids (DHA) on plasma lipid profiles have been inconsistent but may partially depend on individual Apolipoprotein E (APOE) genotypes. We aimed to determine whether APOE genotype modifies the association of lipid profile characteri...

journal_title：Atherosclerosis

authors： Liang S,Steffen LM,Steffen BT,Guan W,Weir NL,Rich SS,Manichaikul A,Vargas JD,Tsai MY

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Molecular imaging with 18Fluorodeoxyglucose (FDG) and 18F-sodium-fluoride (NaF) captures arterial inflammation and micro-calcification and can reveal potentially unstable atherosclerotic plaques. METHODS:We performed FDG and NaF PET/CT imaging in two clinically similar cohorts of patients living wi...

journal_title：Atherosclerosis

authors： Guaraldi G,Milic J,Prandini N,Ligabue G,Esposito F,Ciusa G,Malagoli A,Scaglioni R,Besutti G,Beghetto B,Nardini G,Roncaglia E,Mussini C,Raggi P

更新日期：2020-03-01 00:00:00

abstract：:Detailed lipid composition of serum and isolated lipoprotein fractions in male and female transplant recipients has been determined. Results have been compared with appropriate controls and a number of abnormalities have become apparent: (i) Serum total cholesterol, triglyceride and phospholipid levels were significan...

journal_title：Atherosclerosis

authors： Abbott LK,Elliot C,Aitken JM,Somer JB

更新日期：1978-06-01 00:00:00

abstract：:Polar coordinate mapping was used to determine the rate of growth of individual sudanophilic lesions on the aortic wall around several major branches of the aortae of cholesterol fed rabbits. Four groups, with 6 8-month old male albino white rabbits in each, were used in the study. One group served as a control and th...

journal_title：Atherosclerosis

authors： Roach MR,Fletcher J,Cornhill JF

更新日期：1976-10-01 00:00:00

abstract：:Chylomicron retention disease (CRD) is a rare autosomal recessive disorder characterized by the absence of post-prandial chylomicrons and apolipoprotein (apo) B-48 in sera from affected individuals. Apo B-100 is synthesized, and apo B-100-containing lipoproteins are present in sera. A crucial difference between the sy...

journal_title：Atherosclerosis

authors： Patel S,Pessah M,Beucler I,Navarro J,Infante R

更新日期：1994-08-01 00:00:00

abstract：:Chronic renal failure markedly accelerates atherogenesis in apolipoprotein E-deficient (apoE(-/-)) mice. To study the putative role of receptor for advanced glycation end products (RAGE) in development of uremic atherosclerosis, apoE(-/-) mice received intraperitoneal injections thrice weekly of a neutralizing murine ...

journal_title：Atherosclerosis

authors： Bro S,Flyvbjerg A,Binder CJ,Bang CA,Denner L,Olgaard K,Nielsen LB

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:The purpose of the study was to examine the prevalence and risk factors for cerebral infarction (CI) and carotid artery stenosis (CAS) in patients with peripheral arterial disease (PAD) compared with normal controls. METHOD:A cross-sectional analysis was performed in 857 subjects (PAD: 543, controls: 314). C...

journal_title：Atherosclerosis

authors： Araki Y,Kumakura H,Kanai H,Kasama S,Sumino H,Ichikawa A,Ito T,Iwasaki T,Takayama Y,Ichikawa S,Fujita K,Nakashima K,Minami K,Kurabayashi M

更新日期：2012-08-01 00:00:00

abstract：:Some baboons accumulate appreciable amounts of large apoE-rich HDLs (HDL(1)) which are similar to those reported in humans with several different dyslipoproteinemias. We estimated HDL(1) cholesterol concentrations by gradient gel electrophoresis of serum samples obtained from 634 pedigreed baboons fed with three diets...

journal_title：Atherosclerosis

authors： Rainwater DL,Kammerer CM,Cox LA,Rogers J,Carey KD,Dyke B,Mahaney MC,McGill HC Jr,VandeBerg JL

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To compare lipid-lowering efficacy of adding alirocumab to rosuvastatin versus other treatment strategies (NCT01730053). METHODS:Patients receiving baseline rosuvastatin regimens (10 or 20 mg) were randomized to: add-on alirocumab 75 mg every-2-weeks (Q2W) (1-mL subcutaneous injection via pre-filled pen); ad...

journal_title：Atherosclerosis

authors： Farnier M,Jones P,Severance R,Averna M,Steinhagen-Thiessen E,Colhoun HM,Du Y,Hanotin C,Donahue S

更新日期：2016-01-01 00:00:00

abstract：:The aortic endothelium of rabbits fed a stock diet containing 1 or 2% cholesterol for intervals of 1 day to 21 weeks was compared with that of normal rabbits on a stock diet without cholesterol. The endothelium was examined en face using the Häutchen technique. The aortic endothelium of the experimental animals reveal...

journal_title：Atherosclerosis

authors： Silkworth JB,McLean B,Stehbens WE

更新日期：1975-11-01 00:00:00

abstract：OBJECTIVE:Atherosclerosis is the main underlying cause of the majority of cardiovascular events. Although cardiovascular diseases (CVD) are a major challenge in both males and females, gender specific differences in the prevalence of CVD have been observed. This may indicate that there are differences in the developmen...

journal_title：Atherosclerosis

authors： van den Oord SCH,van der Burg J,Akkus Z,Bosch JG,van Domburg RT,Sijbrands EJG,van der Steen AFW,Schinkel AFL

更新日期：2014-04-01 00:00:00

abstract：:The serum concentrations of testosterone, androstenedione, oestradiol and total low polar oestrogens, mainly oestradiol and oestrone, were measured in 26 healthy male subjects. The subjects were divided into two groups each of them with low (less than 1.04 mmol/l) and high (greater than 1.56 mmol/l) levels of serum HD...

journal_title：Atherosclerosis

authors： Nordøy A,Aakvaag A,Thelle D

更新日期：1979-12-01 00:00:00

abstract：:We studied the effect of lysolecithin on the clearing of plasma cholesterol. The immediate and maximal conversion of plasma lecithin to lysolecithin was produced in rats by intravenous injection of phospholipase A. The changes which took place in the converted lysolecithin and of cholesterol were followed in rats whic...

journal_title：Atherosclerosis

authors： Dobiásová M,Faltová E,Marek J,Obenberger J

更新日期：1975-05-01 00:00:00