Failure of exogenous apoprotein E-3 to enhance cholesterol egress from J-774 murine macrophages in culture.

abstract：:Experiments were performed on thoracic aortae of 12 male Sprague-Dawley [corrected] rats to determine the statistical frequency of isolated leaks to Evans blue-albumin (EBA) conjugate at the level of individual cells and to assess the relationship of such leaks to the cell turnover process. Fluorescence microscopy was...

journal_title：Atherosclerosis

authors： Lin SJ,Jan KM,Schuessler G,Weinbaum S,Chien S

更新日期：1988-10-01 00:00:00

abstract：OBJECTIVE:Although obesity is a risk factor for cardiovascular disease and mortality, several studies have reported that patients with obesity who have suffered acute myocardial infarction or have undergone percutaneous coronary intervention (PCI) have better clinical outcomes than their normal weight counterparts. We ...

journal_title：Atherosclerosis

authors： Sohn GH,Kim EK,Hahn JY,Song YB,Yang JH,Chang SA,Lee SC,Choe YH,Choi SH,Choi JH,Lee SH,Oh JK,Gwon HC

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The role of circular RNAs (circRNAs) in coronary artery disease (CAD) remains elusive. The aim of the present study was to profile circRNAs expression in CAD patients and assess diagnostics biomarkers for CAD. METHODS:The circRNA profiles of 24 CAD patients and 7 controls were assessed by microarra...

journal_title：Atherosclerosis

authors： Wang L,Shen C,Wang Y,Zou T,Zhu H,Lu X,Li L,Yang B,Chen J,Chen S,Lu X,Gu D

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIM:In the general population lipid-rich plaques are prone to rupture and healing of the plaque involves calcification. Patients undergoing hemodialysis have a severe derangement of mineral metabolism and calcification of the arterial tree may have different implications. METHODS:Between 2004 and 2005, ...

journal_title：Atherosclerosis

authors： Bellasi A,Ferramosca E,Ratti C,Block G,Raggi P

更新日期：2016-07-01 00:00:00

abstract：:Ultrasound measurements are both surrogate markers and risk factors for atherosclerosis end points. Carotid intima-media thickness (IMT) is most commonly used, but ultrasound can also define structures in higher spatial dimensions, such as total plaque area (TPA) and total plaque volume (TPV). Because there are minima...

journal_title：Atherosclerosis

authors： Al-Shali K,House AA,Hanley AJ,Khan HM,Harris SB,Mamakeesick M,Zinman B,Fenster A,Spence JD,Hegele RA

更新日期：2005-02-01 00:00:00

abstract：:To examine the relationship between metabolic syndrome and endothelial dysfunction, we investigated cross-sectionally the correlation between metabolic risk factors and urinary excretion of cyclic guanosine 3',5'-monophosphate (cGMP), a second messenger of nitric oxide (NO), in 1541 Japanese men and women aged 40-79 y...

journal_title：Atherosclerosis

authors： Cui R,Iso H,Pi J,Kumagai Y,Yamagishi K,Tanigawa T,Shimamoto T

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Endostatin is implicated in the atherosclerosis process and serves as a promising cardiovascular biomarker, while its clinical significance in ischemic stroke patients remains unclear. We aimed to examine the association between endostatin and mortality and disability after ischemic stroke. METHODS...

journal_title：Atherosclerosis

authors： Zhang C,Qian S,Zhang R,Guo D,Wang A,Peng Y,Peng H,Li Q,Ju Z,Geng D,Chen J,Zhang Y,He J,Zhong C,Xu T

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:This study sought to determine the correlation between baseline cardiac medications and cardiovascular outcomes in patients with obstructive coronary artery disease (CAD) diagnosed by coronary computed tomographic angiography (CCTA). METHODS:1637 patients (mean age 64.8 ± 10.2 years, 69.6% male) with obstruc...

journal_title：Atherosclerosis

authors： Schulman-Marcus J,Hartaigh BÓ,Giambrone AE,Gransar H,Valenti V,Berman DS,Budoff MJ,Achenbach S,Al-Mallah M,Andreini D,Cademartiri F,Callister TQ,Chang HJ,Chinnaiyan K,Chow BJ,Cury R,Delago A,Hadamitzky M,Hausleiter J

更新日期：2015-01-01 00:00:00

abstract：:Free radical mediated oxidation of apoB lipoproteins in the arterial intima appears to contribute to atherogenicity of the entrapped particles. A plausible pathogenic mechanism for oxidation is the one induced by heme leaking from erythrocytes that is then carried into the arterial wall by its high affinity for lipopr...

journal_title：Atherosclerosis

authors： Fernandez AZ,López F,Tablante A,Romano E,Hurt-Camejo E,Camejo G,Apitz-Castro R

更新日期：2001-09-01 00:00:00

abstract：:Incorporation of 125I-labeled cholesterol ester rich lipoproteins from cholesterol fed rabbits into normal rabbit aorta in vitro was inhibited by heparin, lecithin, and collagenase and by succinylation of the lipoprotein. Aortic uptake of lipoprotein was increased by neuraminidase, proteases, lipase, and beta-glucuron...

journal_title：Atherosclerosis

authors： Day CE

更新日期：1976-11-01 00:00:00

abstract：:The effects of lovastatin therapy on concentrations and compositions of lipoproteins were examined in 14 patients with heterozygous familial hypercholesterolemia. The drug lowered plasma levels of cholesterol in total plasma, very low density + intermediate density lipoproteins (VLDL + IDL) and low density lipoprotein...

journal_title：Atherosclerosis

authors： Nozaki S,Vega GL,Haddox RJ,Dolan ET,Grundy SM

更新日期：1990-10-01 00:00:00

abstract：:Several reports have suggested an association between lipid peroxidation and human carotid atherosclerosis, but few reports have demonstrated a link between lipid peroxidation and carotid plaques in humans. In this study, we investigated the relationship between clinical features, histopathological characteristics and...

journal_title：Atherosclerosis

authors： Nishi K,Uno M,Fukuzawa K,Horiguchi H,Shinno K,Nagahiro S

更新日期：2002-02-01 00:00:00

abstract：:We have examined the prevalence of clinically significant atherosclerosis in 78 patients with type III hyperlipoproteinemia (HLP) and homozygosity for apolipoprotein (apo) E2. Forty-six of these individuals (59%) had no atherosclerosis, 32 patients (41%) had atherosclerosis, i.e., atherosclerosis of the extracranial c...

journal_title：Atherosclerosis

authors： Dobmeyer J,Lohrmann J,Feussner G

更新日期：1996-01-05 00:00:00

abstract：:Methylamine can be converted by semicarbazide-sensitive amine oxidase (SSAO) to formaldehyde and hydrogen peroxide, which have been proven to be toxic towards cultured endothelial cells. We investigated whether or not these deaminated products from methylamine can exert potentially hazardous toxic effects in vivo. Lon...

journal_title：Atherosclerosis

authors： Yu PH,Zuo DM

更新日期：1996-02-01 00:00:00

abstract：:Hypertriglyceridemia affects approximately 33% of the US population. Elevated triglyceride levels are independently associated with cardiovascular disease (CVD) risk, and severe hypertriglyceridemia is a risk factor for acute pancreatitis. Guidelines for the management of severe hypertriglyceridemia (≥5.6 mmol/L [≥500...

journal_title：Atherosclerosis

authors： Ito MK

更新日期：2015-10-01 00:00:00

abstract：:The effects of administration of pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, on hepatic cholesterol 7 alpha-hydroxylase and acyl-coenzyme A: cholesterol acyltransferase (ACAT) activities and bile lipid secretion were investigated in Syrian golden hamsters. Continuous administrat...

journal_title：Atherosclerosis

authors： Hayashi K,Noshiro M,Kurushima H,Kuga Y,Nomura S,Ohkura Y,Ohtani H,Kurokawa J,Tanaka K,Yasunobu Y

更新日期：1994-12-01 00:00:00

abstract：:The hypolipidemic response of rice bran oil (RBO) was investigated in nonhuman primates fed semi-purified diets containing blends of oils which included RBO at 0-35% Kcals as dietary fat. The studies demonstrated the following: (a) the degree of reduction of serum total cholesterol (TC) and low density lipoprotein cho...

journal_title：Atherosclerosis

authors： Nicolosi RJ,Ausman LM,Hegsted DM

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Atherosclerosis and non-alcoholic fatty liver disease (NAFLD) are complex pathologies characterized by lipid accumulation, chronic inflammation and extensive tissue remodelling. Microparticles (MPs), small membrane vesicles produced by activated and apoptotic cells, might not only be biomarkers, but also fun...

journal_title：Atherosclerosis

authors： Baron M,Leroyer AS,Majd Z,Lalloyer F,Vallez E,Bantubungi K,Chinetti-Gbaguidi G,Delerive P,Boulanger CM,Staels B,Tailleux A

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:Interleukin (IL)-6 is a key modulator of the acute phase response (APR), and while both are implicated in atherosclerosis, the pathological role of specific IL-6 signalling cascades is ill-defined. Since IL-6 employs the cytokine receptor gp130 to primarily activate the STAT3 pathway, here we evaluate whether...

journal_title：Atherosclerosis

authors： Jones GW,McLeod L,Kennedy CL,Bozinovski S,Najdovska M,Jenkins BJ

更新日期：2015-02-01 00:00:00

abstract：:Hypercholesterolemia impairs endothelial function. However, the production/release of nitric oxide from the hypercholesterolemic aorta is reported to be enhanced rather than impaired in animal studies. L-arginine improves endothelial function in hypercholesterolemic subjects. The goal of the present study was to inves...

journal_title：Atherosclerosis

authors： Kawano H,Motoyama T,Hirai N,Kugiyama K,Yasue H,Ogawa H

更新日期：2002-04-01 00:00:00

abstract：:The relative importance of reduced plasma high density lipoprotein-cholesterol (HDL-C) levels and elevated plasma triglyceride (TG) concentrations as risk factors for ischemic heart disease (IHD) was examined in a sample of 2177 men from the Québec City suburbs. The sample included 202 men with known IHD. The relation...

journal_title：Atherosclerosis

authors： Lamarche B,Després JP,Moorjani S,Cantin B,Dagenais GR,Lupien PJ

更新日期：1996-01-26 00:00:00

abstract：:Whether an association, causative or not, exists between the level of serum selenium and the risk of ischaemic heart disease (IHD) remains unsettled. We investigated the issue in a cohort of 3387 males aged 53-74 years (mean 63). Based on information about health status, life-style and socioeconomic factors given in a...

journal_title：Atherosclerosis

authors： Suadicani P,Hein HO,Gyntelberg F

更新日期：1992-09-01 00:00:00

abstract：:Tranilast (N(3,4-dimethoxycinnamoyl)anthranilic acid), an agent which in cell culture inhibits transforming growth factor-beta (TGF-beta) secretion and antagonises the effects of TGF-beta and platelet-derived growth factor (PDGF) on cell migration and proliferation, has been reported to reduce the incidence of resteno...

journal_title：Atherosclerosis

authors： Ward MR,Sasahara T,Agrotis A,Dilley RJ,Jennings GL,Bobik A

更新日期：1998-04-01 00:00:00

abstract：:The possibility that Fas/APO 1 is involved in the apoptosis of advanced human coronary atherosclerosis was examined in the present study. Coronary arteries with atherosclerosis were obtained from human hearts with chronic ischemic heart disease at cardiac transplantation. Normal vessels were used as controls. Fas/APO ...

journal_title：Atherosclerosis

authors： Cai W,Devaux B,Schaper W,Schaper J

更新日期：1997-06-01 00:00:00

abstract：:An attempt was made to explore the reasons why men develop coronary heart disease (CHD) despite being at low risk on the basis of established risk factors. A case control study was designed to take place after the end of a longitudinal study in which both low- and high-risk men who had developed CHD over the course of...

journal_title：Atherosclerosis

authors： Heller RF,Miller NE,Wheeler MJ,Kind PR

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND AND AIMS:We investigated placental histopathology for lesions that are associated with maternal and fetal circulation abnormalities in obese pregnant women with and without metabolic alterations. METHODS:332 pregnant women were divided into three groups: Group 1 included 163 non-obese metabolically healthy ...

journal_title：Atherosclerosis

authors： Bar J,Kovo M,Schraiber L,Shargorodsky M

更新日期：2017-05-01 00:00:00

abstract：UNLABELLED:In the last few years it has been proved that risk factors for atherosclerosis are present in children and adolescents, and that already at this early age they are connected with anatomic, atheromatous changes in vessels. These changes can not be fully explained as occurring in young people exhibiting tradit...

journal_title：Atherosclerosis

authors： Glowinska B,Urban M,Koput A,Galar M

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:Given the high risk of cardiovascular disease in South Asians and the importance of inflammation in coronary heart disease we tested the hypothesis that circulating C-reactive protein (CRP) and interleukin 6 (IL-6) would be higher in healthy British born infants of South Asian origin than in infants of Europe...

journal_title：Atherosclerosis

authors： Oldroyd JC,Heald A,Bansal N,Vyas A,Siddals K,Gibson M,Clayton P,Cruickshank JK

更新日期：2009-11-01 00:00:00

abstract：:Endothelium-derived relaxing and contracting factors play an important role in atherosclerosis, re-stenosis and graft survival. Internal thoracic artery (ITA) and saphenous vein (SV) are used as conduit vessels in coronary artery bypass graft surgery (CABG). The long-term graft patency rate is higher with ITA than SV....

journal_title：Atherosclerosis

authors： Hamilton CA,Berg G,Mcintyre M,Mcphaden AR,Reid JL,Dominiczak AF

更新日期：1997-08-01 00:00:00

abstract：:The heavy and light subfractions of low density lipoprotein (LDL) were bound to the same extent and with the same affinity by the LDL receptors of cultured human fibroblasts, both when assayed at 4 degrees C and when assayed at 37 degrees C. They were also degraded similarly by the low affinity, LDL-receptor-mediated ...

journal_title：Atherosclerosis

authors： Knight BL,Thompson GR,Soutar AK

更新日期：1986-03-01 00:00:00