当前位置： SCI文献检索 > ATHEROSCLEROSIS期刊下所有文献 > Metabolic syndrome and urinary cGMP excretion in general population.

Metabolic syndrome and urinary cGMP excretion in general population.

Abstract：

:To examine the relationship between metabolic syndrome and endothelial dysfunction, we investigated cross-sectionally the correlation between metabolic risk factors and urinary excretion of cyclic guanosine 3',5'-monophosphate (cGMP), a second messenger of nitric oxide (NO), in 1541 Japanese men and women aged 40-79 years. The 24-h urinary excretion of cGMP was measured using a (125)I-labeled cGMP radioimmunoassay and was adjusted for urinary creatinine excretion (nmol/mmol creatinine). The components of metabolic syndrome were defined based on the following criteria: body mass index (BMI)> or =25.0 kg/m(2), fasting plasma glucose> or =6.11 mmol/l or non-fasting plasma glucose level> or =11.1 mmol/l, systolic blood pressure> or =130 mm Hg or diastolic blood pressure> or =85 mm Hg, high-density lipoprotein (HDL)-cholesterol<1.03 mmol/l for men and <1.29 mmol/l for women, and triglyceride> or =1.69 mmol/l. The number of components of metabolic syndrome correlated inversely with urinary cGMP excretion; means of cGMP excretion for the whole group adjusted for age, sex, and cardiovascular risk factors were 53.6, 48.6, 47.9, 44.4 and 42.3 nmol/mmol for 0, 1, 2, 3, and 4-5 components of metabolic syndrome, respectively (p=0.002). Our data suggest that a reduction of NO bioactivity concur with clustered features of the metabolic syndrome.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Cui R,Iso H,Pi J,Kumagai Y,Yamagishi K,Tanigawa T,Shimamoto T

doi

10.1016/j.atherosclerosis.2006.02.032

keywords:

subject

Has Abstract

pub_date

2007-02-01 00:00:00

pages

423-8

issue

2

eissn

0021-9150

issn

1879-1484

pii

S0021-9150(06)00076-1

journal_volume

190

pub_type

杂志文章,多中心研究

相关文献

ATHEROSCLEROSIS文献大全
  • The effect of statins on ABCA1 and ABCG1 expression in human macrophages is influenced by cellular cholesterol levels and extent of differentiation.

    abstract：:The ATP-binding cassette transporters, ABCA1 and ABCG1, are LXR-target genes that participate in the removal of cholesterol from lipid-laden macrophages, a crucial anti-atherogenic mechanism. Statins are currently the most efficacious therapy for the treatment of hypercholesterolemia and cardiovascular disease. We and...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2007.03.030

    authors： Wong J,Quinn CM,Gelissen IC,Jessup W,Brown AJ

    更新日期：2008-01-01 00:00:00

  • Distribution of apolipoprotein E between apo B- and non apo B-containing lipoproteins according to apo E phenotype.

    abstract：:Apolipoprotein E (apo E) is a component of all the classes of lipoproteins and can be distributed among apo B- (LpB) and non apo B-containing lipoproteins (Lp-non-B). Using a new electroimmunoassay kit, plasma apo E, apo E in Lp-non-B (apo E-Lp-non-B) and apo E in LpB (apo E-LpB) levels were measured in healthy contro...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,多中心研究

    doi：10.1016/s0021-9150(97)00053-1

    authors： Luc G,Ducimetiere P,Bard JM,Arveiler D,Evans A,Cambien F,Fruchart JC,Fievet C

    更新日期：1997-06-01 00:00:00

  • Pulse wave velocity is associated with early clinical outcome after ischemic stroke.

    abstract：BACKGROUND AND PURPOSES:Pulse wave analysis (PWV), a marker of aortic stiffness, has independent predictive value for cardiovascular morbidity and mortality in both healthy and high-risk populations, especially fatal stroke, and for long-term functional stroke prognosis. Whether arterial stiffness and wave reflection a...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2012.09.024

    authors： Gąsecki D,Rojek A,Kwarciany M,Kowalczyk K,Boutouyrie P,Nyka W,Laurent S,Narkiewicz K

    更新日期：2012-12-01 00:00:00

  • Genetic and environmental covariance of serum cholesterol and blood pressure in female twins.

    abstract：:Blood pressure elevation is frequently associated with elevated cholesterol, triglyceride or low density lipoprotein (LDL-C) or low high density lipoprotein (HDL-C). The relative importance of genetic and environmental factors in these associations is unclear. We examined the relative contribution of genetic and envir...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(93)90064-2

    authors： Williams PD,Puddey IB,Martin NG,Beilin LJ

    更新日期：1993-04-01 00:00:00

  • Endothelial dysfunction in hypercholesterolemia is improved by L-arginine administration: possible role of oxidative stress.

    abstract：:Hypercholesterolemia impairs endothelial function. However, the production/release of nitric oxide from the hypercholesterolemic aorta is reported to be enhanced rather than impaired in animal studies. L-arginine improves endothelial function in hypercholesterolemic subjects. The goal of the present study was to inves...

    journal_title：Atherosclerosis

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0021-9150(01)00671-2

    authors： Kawano H,Motoyama T,Hirai N,Kugiyama K,Yasue H,Ogawa H

    更新日期：2002-04-01 00:00:00

  • Daily supplementation with aged garlic extract, but not raw garlic, protects low density lipoprotein against in vitro oxidation.

    abstract：:The oxidation of low density lipoprotein (LDL) is believed to be an important process in the development and progression of atherosclerosis. In this study, human subjects were supplemented daily with one of: 6 g raw garlic; 2.4 g aged garlic extract (AGE); or 0.8 g DL-alpha-tocopherol acetate for 7 days to determine t...

    journal_title：Atherosclerosis

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0021-9150(98)00293-7

    authors： Munday JS,James KA,Fray LM,Kirkwood SW,Thompson KG

    更新日期：1999-04-01 00:00:00

  • Total cholesterol and stroke mortality in middle-aged and elderly adults: A prospective cohort study.

    abstract：BACKGROUND AND AIMS:The association between cholesterol and stroke has been inconsistent. This study aimed to examine the association between total cholesterol (TC) and mortality from total stroke and stroke subtypes. METHODS:503,340 Korean adults aged 40-80 years without a history of heart disease or stroke participa...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2017.12.003

    authors： Yi SW,Shin DH,Kim H,Yi JJ,Ohrr H

    更新日期：2018-03-01 00:00:00

  • Serum total and high density lipoprotein (HDL) cholesterol concentrations in rural and urban boys from 16 countries.

    abstract：:Serum total and HDL cholesterol concentrations were measured in schoolboy populations from 16 countries. Total and HDL cholesterol concentrations were determined in one laboratory to reduce methodological variability as much as possible. A standardized protocol was used for the drawing of blood, preparation, storage a...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(80)90245-2

    authors： Knuiman JT,Hermus RJ,Hautvast JG

    更新日期：1980-08-01 00:00:00

  • Changes in aortic endothelial gene expressions and relaxation responses following chronic short-term insulin treatment in diabetic rats.

    abstract：:The purpose of the present study was to examine the relationship between the changes in the expressions of several mRNAs and changes in endothelial function in streptozotocin-induced diabetic and chronic short-term insulin-treated rats. Aortas from later-stage (10 week) diabetics, but not those from their insulin-trea...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2005.05.026

    authors： Kobayashi T,Oishi K,Hayashi Y,Matsumoto T,Kamata K

    更新日期：2006-03-01 00:00:00

  • Mediterranean diet and carotid atherosclerosis in the Northern Manhattan Study.

    abstract：OBJECTIVE:Adherence to a Mediterranean-style diet (MeDi) may protect against clinical vascular events by reducing atherosclerosis, but data is limited. This is the first observational study of the association between MeDi adherence and carotid plaque thickness and area. METHODS:The study included 1374 participants of ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2014.03.011

    authors： Gardener H,Wright CB,Cabral D,Scarmeas N,Gu Y,Cheung K,Elkind MS,Sacco RL,Rundek T

    更新日期：2014-06-01 00:00:00

  • Circulating levels of MCP-1 and eotaxin are not associated with presence of atherosclerosis or previous myocardial infarction.

    abstract：:The chemokines are a family of signalling proteins that participate in regulation of the immune system and have been implicated in the pathogenesis of vascular diseases. Deleting the gene encoding the chemokine MCP-1 in mouse models of atherosclerosis reduces lipid lesion formation and circulating chemokines are upreg...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2004.11.028

    authors： Mosedale DE,Smith DJ,Aitken S,Schofield PM,Clarke SC,McNab D,Goddard H,Gale CR,Martyn CN,Bethell HW,Barnard C,Hayns S,Nugent C,Panicker A,Grainger DJ

    更新日期：2005-12-01 00:00:00

  • Evaluation of cholesterol lowering treatment of patients with familial hypercholesterolemia: a large cross-sectional study in The Netherlands.

    abstract：BACKGROUND:Heterozygous familial hypercholesterolemia (heFH) is a common autosomal dominant hereditary disorder caused by mutations in the LDL-receptor gene that lead to elevated plasma levels of low-density lipoprotein-cholesterol (LDL-c). Robust lowering of LDL-c levels is essential for risk reduction of premature ca...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2009.09.014

    authors： Pijlman AH,Huijgen R,Verhagen SN,Imholz BP,Liem AH,Kastelein JJ,Abbink EJ,Stalenhoef AF,Visseren FL

    更新日期：2010-03-01 00:00:00

  • Effect of risk factors and antirheumatic drugs on the proliferation of aortic wall cells.

    abstract：:The proliferation of aortic smooth muscle cells (ASMC) of Wistar rats, impaired by risk factors such as arterial hypertension, diabetes mellitus, atherogenic diet and staphylolysin injections and of normal Wistar rats treated with antirheumatic drugs such as prednisolone and acetylsalicylic acid was investigated. The ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(79)90135-7

    authors： Hauss WH,Mey J,Schulte H

    更新日期：1979-10-01 00:00:00

  • Common carotid intima-media thickness in patients with peripheral arterial disease or abdominal aortic aneurysm: the SMART study. Second Manifestations of ARTerial disease.

    abstract：:Evidence is emerging that the contribution of atherosclerosis to the development of abdominal aortic aneurysm may differ from that of other manifestations of arterial disease. B-mode ultrasound may be helpful in understanding the characteristics and factors that contribute to the development of different manifestation...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(99)00142-2

    authors： Simons PC,Algra A,Bots ML,Banga JD,Grobbee DE,van der Graaf Y

    更新日期：1999-10-01 00:00:00

  • Fluvastatin therapy improves microcirculation in patients with hyperlipidaemia.

    abstract：:The purpose of this study was to investigate the effect of fluvastatin on the microcirculation of patients with hyperlipidaemia (low-density lipoprotein cholesterol > 160 mg/dL, triglycerides < 350 mg/dl) inadequately controlled by diet. After a dietary run-in of 4 weeks, patients were randomised in a double-blind stu...

    journal_title：Atherosclerosis

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0021-9150(00)00567-0

    authors： Haak E,Abletshauser C,Weber S,Goedicke C,Martin N,Hermanns N,Lackner K,Kusterer K,Usadel KH,Haak T

    更新日期：2001-04-01 00:00:00

  • Atherosclerotic plaque-like lesions in synthetic arteriovenous grafts: implications for atherogenesis.

    abstract：:Atherosclerotic plaque-like lesions are prevalent in synthetic arteriovenous shunts created to provide vascular access for hemodialysis. Similarities to atherosclerotic plaques in native arteries include eccentric location, immunoreactivity for smooth muscle actin, dystrophic calcifications, superimposed thrombi, and ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(01)00543-3

    authors： Sloop GD,Fallon KB,Zieske AW

    更新日期：2002-01-01 00:00:00

  • Dose-response effect of single and combined clofibrate (Atromidin) and niceritrol (Perycit) treatment on serum lipids and lipoproteins in type II hyperlipoproteinaemia.

    abstract：:The dose-response effects of clofibrate and niceritrol on serum cholesterol and triglycerides (TG) were studied in 29 patients with Type IIa and IIb hyperlipoproteinaemia. In 17 patients, clofibrate and niceritrol were then given as combined treatment, and the effects of this combination on serum lipoproteins were stu...

    journal_title：Atherosclerosis

    pub_type： 临床试验,杂志文章

    doi：10.1016/0021-9150(75)90070-2

    authors： Olsson AG,Orö L,Rössner S

    更新日期：1975-07-01 00:00:00

  • Localized vessel expression of lipoprotein lipase in rabbits leads to rapid lipid deposition in the balloon-injured arterial wall.

    abstract：:Recent studies on mice demonstrated that lipoprotein lipase (LPL) located in the arterial wall might play a pro-atherogenic role. There are major differences between humans and mice in lipoprotein metabolism and in susceptibility to atherosclerosis. We have therefore used rabbits fed normal chow diet as a model to ass...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2005.08.032

    authors： Wu X,Wang J,Fan J,Chen M,Chen L,Huang W,Liu G

    更新日期：2006-07-01 00:00:00

  • Effects of polymorphisms of methionine synthase and methionine synthase reductase on total plasma homocysteine in the NHLBI Family Heart Study.

    abstract：:The metabolism of homocysteine requires contributions of several enzymes and vitamin cofactors. Earlier studies identified a common polymorphism of methylenetetrahydrofolate reductase that was associated with mild hyperhomocysteinemia. Common variants of two other enzymes involved in homocysteine metabolism, methionin...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(02)00204-6

    authors： Jacques PF,Bostom AG,Selhub J,Rich S,Ellison RC,Eckfeldt JH,Gravel RA,Rozen R,National Heart, Lung and Blood Institute, National Institutes of Health.

    更新日期：2003-01-01 00:00:00

  • Effects of medication, treatment, and behavioral beliefs on intentions to take medication in patients with familial hypercholesterolemia.

    abstract：BACKGROUND AND AIMS:Although familial hypercholesterolemia (FH) can be effectively managed using cholesterol-lowering medication, patients often fall short of complete treatment adherence. Identifying the psychological factors associated with self-regulation of FH medication is important to inform interventions to maxi...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.atherosclerosis.2018.06.010

    authors： Hagger MS,Hardcastle SJ,Hu M,Kwok S,Lin J,Nawawi HM,Pang J,Santos RD,Soran H,Su TC,Tomlinson B,Watts GF

    更新日期：2018-10-01 00:00:00

  • Cholestanol: a serum marker to guide LDL cholesterol-lowering therapy.

    abstract：:Statins have been the mainstay of lipid-lowering therapy since their introduction. However, as lower LDL cholesterol targets are sought, adjunct therapies are becoming increasingly important. Few patients reach new targets with statin monotherapy. We propose that the cholestanol:cholesterol ratio can be used to guide ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,评审

    doi：10.1016/j.atherosclerosis.2005.09.007

    authors： Hoenig MR,Rolfe BE,Campbell JH

    更新日期：2006-02-01 00:00:00

  • Embolic complications after carotid artery stenting or carotid endarterectomy are associated with tissue characteristics of carotid plaques evaluated by magnetic resonance imaging.

    abstract：BACKGROUND:Unstable carotid plaques are associated with an increased incidence of embolic complications after carotid artery stenting (CAS) or carotid endarterectomy (CEA). The aim of this study was to elucidate the relationship between the tissue components of carotid plaques and the incidence of new ipsilateral silen...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2011.01.002

    authors： Yamada K,Yoshimura S,Kawasaki M,Enomoto Y,Asano T,Hara A,Minatoguchi S,Iwama T

    更新日期：2011-04-01 00:00:00

  • Maternal smoking in pregnancy is associated with cholesterol development in the offspring: A 27-years follow-up study.

    abstract：OBJECTIVE:To examine the associations of maternal smoking in pregnancy with development of cholesterol levels from childhood to adulthood. METHODS:Total cholesterol, high-density lipoprotein (HDL) cholesterol and low-density lipoprotein (LDL) cholesterol were measured annually from 1975 to 1993 and in 2002 in 350 subj...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2007.01.032

    authors： Jaddoe VWV,de Ridder MAJ,van den Elzen APM,Hofman A,Uiterwaal CSPM,Witteman JCM

    更新日期：2008-01-01 00:00:00

  • Calculation of LDL apoB.

    abstract：OBJECTIVES:This study tests the validity of the Hattori formula to calculate LDL apoB based on plasma lipids and total apoB. METHODS:In 2178 patients in a tertiary care lipid clinic, LDL apoB calculated as suggested by Hattori et al. was compared to directly measured LDL apoB isolated by ultracentrifugation. RESULTS:...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2014.03.012

    authors： Sniderman AD,Tremblay AJ,De Graaf J,Couture P

    更新日期：2014-06-01 00:00:00

  • Heparin-stimulated expression of extracellular-superoxide dismutase in human fibroblasts.

    abstract：:Extracellular-superoxide dismutase (EC-SOD) is the major SOD isozyme in the arterial wall and may be important for antioxidation capability of the vascular wall and normal vascular function. EC-SOD is expressed in various cell types in the vascular wall such as fibroblasts, smooth muscle cells and macrophages, and the...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(01)00512-3

    authors： Adachi T,Hara H,Yamada H,Yamazaki N,Yamamoto M,Sugiyama T,Futenma A,Katagiri Y

    更新日期：2001-12-01 00:00:00

  • [Aortic development and ageing in the rat aorta -- Comparative histochemical and histoenzymological study (author's transl)].

    abstract：:A comparative study was made of 36 aortic enzyme activities (E.A.) and 6 macromelecular substances at different stages of ontogenesis in 49 male rats. In the foetal aorta (19th day) the E.Z. were moderate or weak and restricted to a few metabolic pathways: glycolysis, diaphorases, esterolysis of some nucleotides and g...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(75)90065-9

    authors： Hadjiisky P,Renais J,Scebat L

    更新日期：1975-07-01 00:00:00

  • Evidence for a reversal with age in the pattern of near-wall blood flow around aortic branches.

    abstract：:The changes that occur with age in the distribution of atherosclerotic lesions around arterial branch points challenge accepted theories relating disease to haemodynamic stresses. We investigated whether flow near branch points changes with age in a way that can account for the different lesion distributions. Flow aro...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2003.09.028

    authors： Al-Musawi SL,Bishton J,Dean J,Williams S,Cremers SG,Weinberg PD

    更新日期：2004-01-01 00:00:00

  • Peritoneal macrophages are distinct from monocytes and adherent macrophages.

    abstract：OBJECTIVE:Peritoneal macrophages are used in many studies related to atherosclerosis. In situ, they are non-adherent and upon culturing, they adhere and function as scavengers of modified lipoproteins and dead apoptotic cells. They also produce growth factors, suggesting that they may provide life-supporting function a...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2011.09.014

    authors： Selvarajan K,Moldovan L,Chandrakala AN,Litvinov D,Parthasarathy S

    更新日期：2011-12-01 00:00:00

  • Relationship between plasma coenzyme Q10, asymmetric dimethylarginine and arterial stiffness in patients with phenotypic or genotypic familial hypercholesterolemia on long-term statin therapy.

    abstract：OBJECTIVE:We investigated whether statin-treated heterozygous familial hypercholesterolemic (FH) patients have lower plasma coenzyme Q(10) (CoQ(10)) levels than low-density lipoprotein receptor (LDLR) mutation negative FH patients on equivalent statin doses, and whether lower CoQ(10) concentrations are associated with ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2011.04.034

    authors： Young JM,Molyneux SL,Reinheimer AM,Florkowski CM,Frampton CM,Scott RS,George PM

    更新日期：2011-09-01 00:00:00

  • The influence of apoE-deficiency and LDL-receptor-deficiency on the HDL subpopulation profile in mice and in humans.

    abstract：OBJECTIVE:As apoE(-/-) and LDL-Receptor(-/-) mice are commonly used in atherosclerosis research; our objective was to point out the differences in HDL metabolism between mice and humans regarding the roles of apoE and LDLR. METHODS:We examined HDL particles obtained from wild type (WT), LDLR(-/-), and apoE(-/-) mice, ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2013.11.080

    authors： Tani M,Matera R,Horvath KV,Hasan TS,Schaefer EJ,Asztalos BF

    更新日期：2014-03-01 00:00:00