Abstract：
:Detailed lipid composition of serum and isolated lipoprotein fractions in male and female transplant recipients has been determined. Results have been compared with appropriate controls and a number of abnormalities have become apparent: (i) Serum total cholesterol, triglyceride and phospholipid levels were significantly elevated in transplant recipients. (ii) All lipid classes VLDL were significantly increased in both male and female patients. (iii) LDL-total cholesterol, triglyceride and phospholipid were significantly raised in female transplant patients, but this was true only for LDL-triglyceride in male patients. (iv) In female patients, HDL-total cholesterol and -triglyceride were significantly elevated, while in male patients, HDL-total cholesterol, but not HDL-triglyceride, was significantly greater than in controls. (v) The ratio of esterified to free cholesterol was significantly reduced in HDL of female transplant recipients. Results from correlation analysis suggest a relationship between some of the lipid abnormalities and renal function in female patients, while in male patients only immunosuppressive therapy is implicated.
journal_name
Atherosclerosisjournal_title
Atherosclerosisauthors
Abbott LK,Elliot C,Aitken JM,Somer JBdoi
10.1016/0021-9150(78)90053-9subject
Has Abstractpub_date
1978-06-01 00:00:00pages
97-107issue
2eissn
0021-9150issn
1879-1484pii
0021-9150(78)90053-9journal_volume
30pub_type
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