Abstract:
:DNA probes for all eight of the major apolipoprotein genes are now available. The chromosomal location, the basic structure and in many cases the nucleotide sequences of the normal genes are known. Common DNA polymorphisms of all of the genes have been detected. These have been been used in a number of ways to investigate rare inherited defects of the apolipoprotein genes, to study the potential involvement of different variants of the genes in the development of hyperlipidaemia in patients, and to investigate the contribution of common variation in these genes in the determination of serum lipid levels in the normal population.
journal_name
Atherosclerosisjournal_title
Atherosclerosisauthors
Humphries SEdoi
10.1016/0021-9150(88)90069-xsubject
Has Abstractpub_date
1988-08-01 00:00:00pages
89-108issue
2-3eissn
0021-9150issn
1879-1484pii
0021-9150(88)90069-Xjournal_volume
72pub_type
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