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Evaluation of the oral hypoglycaemic effect of Trigonella foenum-graecum L. (methi) in normal mice.

Abstract：

:Trigonella foenum-graecum (Fenugreek) (Leguminosae) is employed as a herbal medicine. Its seeds are known for their carminative, tonic and antidiabetic effects. A curative dose of Trigonella foenum-graecum also produces antiulcer action. In this study we have investigated the hypoglycaemic activities of the aqueous extract of the seeds Trigonella foenum-graecum in normal mice using oral route of adminstration. The methanolic extract administered through the same route produced hypoglycaemic effect only at the dose of 1 g/kg body weight. The aqueous extract is under further investigation to determine the chemical structure of the active component. The presence of hypoglycaemic activity in aqueous and methanolic extract indicates that the active compounds are polar in nature.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Zia T,Hasnain SN,Hasan SK

doi

10.1016/s0378-8741(01)00186-6

keywords:

subject

Has Abstract

pub_date

2001-05-01 00:00:00

pages

191-5

issue

2-3

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(01)00186-6

journal_volume

75

pub_type

杂志文章

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