Glucocorticoid-induced osteoporosis.

abstract：:While the most obvious manifestations of rheumatoid arthritis (RA) involve inflammation and damage in the synovial joints, the systemic effects of the condition are widespread and life-threatening. Of particular interest is the 'lipid paradox' of RA, where patients with a numerically equivocal starting lipid profile h...

journal_title：Current rheumatology reports

authors： McGrath CM,Young SP

更新日期：2015-09-01 00:00:00

abstract：:Although the pathogenesis of SLE remains poorly understood, there is consensus that it involves a combination of genetic, hormonal, and environmental factors. New technologies applied to genomic and gene expression studies have revealed novel gene mutations and cytokine alterations in this disease. Recently, advances ...

journal_title：Current rheumatology reports

authors： Stichweh D,Pascual V

更新日期：2005-12-01 00:00:00

abstract：:Juvenile idiopathic arthritis (JIA) is in a majority of the cases of self-limiting, and sometimes even a self-remitting, disease. A growing amount of data suggests that active T cell regulation determines, at least partly, the clinical outcome of JIA. In experimental models of arthritis, a group of highly conserved mi...

journal_title：Current rheumatology reports

authors： Prakken B,Kuis W,van Eden W,Albani S

更新日期：2002-12-01 00:00:00

abstract：:TNF-blocking biologics have revolutionized the care of patients with spondyloarthritis, a group of clinically overlapping conditions that includes ankylosing spondylitis and psoriatic arthritis. However, incomplete response rates speak to the need for alternative therapeutic approaches. Over the last decade, animal mo...

journal_title：Current rheumatology reports

authors： Smith JA

更新日期：2016-06-01 00:00:00

abstract：:Apatite crystals form in physiologically calcified tissues, including the hyaline cartilage of the epiphyseal growth plate. While apatite crystals appear as unwanted deposits in other cartilage sites, more frequently, crystalline materials other than or in addition to apatite develop in dystrophic cartilage deposits. ...

journal_title：Current rheumatology reports

authors： Boskey AL

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Gout management is currently suboptimal despite excellent available therapy. Gout patient education has been shown to enhance medication adherence and self-management, but needs improvement. We explored the literature on gout patient education including gaps in gout patient knowledge; use of written m...

journal_title：Current rheumatology reports

authors： Fields TR,Batterman A

更新日期：2018-03-08 00:00:00

abstract：:Sjögren's syndrome is a chronic inflammatory process involving primarily the exocrine glands. Its association with lymphoma is well documented. A low-grade marginal-zone lymphoma related to mucosa-associated lymphoid tissue is the most common lymphoid neoplasia in Sjögren's syndrome. Among all autoimmune diseases, Sjö...

journal_title：Current rheumatology reports

authors： Voulgarelis M,Moutsopoulos HM

更新日期：2003-08-01 00:00:00

abstract：:Inflammatory joint diseases such as rheumatoid arthritis, as well as other rheumatic conditions, such as systemic lupus erythematosus (SLE) and ankylosing spondylitis, comprise a heterogeneous group of joint disorders that are all associated with extra-articular side effects, including bone loss and fractures. The con...

journal_title：Current rheumatology reports

authors： Bultink IE,Vis M,van der Horst-Bruinsma IE,Lems WF

更新日期：2012-06-01 00:00:00

abstract：:The inflammatory myopathies are a heterogeneous group of diseases including dermatomyositis, polymyositis, and inclusion body myositis. Few clinical trials have been conducted in myositis, making it difficult to provide clear recommendations on the treatment of these rare disorders. Although corticosteroids have not b...

journal_title：Current rheumatology reports

authors： Aggarwal R,Oddis CV

更新日期：2011-06-01 00:00:00

abstract：:There is a wide variation in the prevalence, incidence, and clinical manifestation of psoriatic arthritis (PsA) across countries due to genetic and environmental factors. Data on PsA in Asia are limited and come from small cross-sectional studies. The burden of PsA in Asia is high, including poor physical functioning,...

journal_title：Current rheumatology reports

authors： Leung YY,Tam LS,Li EK

更新日期：2011-08-01 00:00:00

abstract：:Traditional nonsteroidal anti-inflammatory drugs block cyclooxygenase (COX). They are the most widely used drugs for pain relief. They are indispensable for their effects but are condemned for their adverse drug reactions. Two COX inhibitors, acetaminophen and aspirin, are the most widely used over-the-counter drugs. ...

journal_title：Current rheumatology reports

authors： Brune K,Hinz B,Otterness I

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Idiopathic acute and recurrent pericarditis are rare diseases of unknown origin. Here, we review trigger factors, pathomechanism, and treatment options for acute and recurrent pericarditis. RECENT FINDINGS:Acute pericarditis can be triggered by viral infections, myocardial ischemia, heart cathete...

journal_title：Current rheumatology reports

authors： Blank N,Lorenz HM

更新日期：2019-03-09 00:00:00

abstract：:Psoriatic arthritis (PsA) is a chronic inflammatory joint disease associated with psoriasis that can lead to joint deformity and disability. PsA has a low likelihood of clinical remission and cure. For a long time, therapeutic options for PsA patients have been unsatisfactory, but the introduction of anti-tumor necros...

journal_title：Current rheumatology reports

authors： de Vlam K,Lories RJ

更新日期：2008-08-01 00:00:00

abstract：:Hereditary hemochromatosis is a frequent disease in Caucasian populations. It leads to progressive iron overload in a variety of organs. The most common cause is the C282Y homozygous mutation in the HFE gene. The classical triad of skin hyperpigmentation, diabetes, and liver cirrhosis is nowadays rare but musculoskele...

journal_title：Current rheumatology reports

authors： Husar-Memmer E,Stadlmayr A,Datz C,Zwerina J

更新日期：2014-01-01 00:00:00

abstract：:Antiphospholipid antibodies are associated with a hypercoagulable state leading to a wide variety of systemic manifestations and obstetric complications. The different pathologic manifestations can be a result of arterial and venous thrombosis, microthrombotic angiopathy, embolization, obstetric disease, and non-throm...

journal_title：Current rheumatology reports

authors： DeMarco P,Singh I,Weinstein A

更新日期：2006-04-01 00:00:00

abstract：:Osteoporosis is a potentially preventable condition frequently encountered in patients with systemic lupus erythematosus (SLE). Bone loss in SLE is likely a multi- factorial process involving traditional osteoporosis risk factors along with lupus-related factors. Recognizing potential contributors to bone loss in pati...

journal_title：Current rheumatology reports

authors： Lee C,Ramsey-Goldman R

更新日期：2005-12-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is a devastating complication of systemic sclerosis (SSc). Although there are screening tests for PAH, such as carbon monoxide diffusing capacity and Doppler echocardiography, these tests are far from perfect, patients are still identified late in the course of disease, and the un...

journal_title：Current rheumatology reports

authors： Shah SJ

更新日期：2009-04-01 00:00:00

abstract：:Scleroderma renal crisis (SRC) is characterized by malignant hypertension, oliguric/anuric acute renal failure, and important mortality, with a 5-year survival rate of 65%. SRC occurs in 2% to 5% of patients with systemic sclerosis (SSc), particularly those with diffuse cutaneous SSc in the first years of disease evol...

journal_title：Current rheumatology reports

authors： Bussone G,Bérezné A,Pestre V,Guillevin L,Mouthon L

更新日期：2011-02-01 00:00:00

abstract：:Erosive osteoarthritis (OA) is a subcategory of OA in which destructive changes occur in the joints, probably as a result of a combination of inflammatory inciters and phenomena. The major changes occur in the distal and proximal interphalangeal joints, root joints of the thumb, and less commonly other hand and centri...

journal_title：Current rheumatology reports

authors： Ehrlich GE

更新日期：2001-12-01 00:00:00

abstract：:Health outcomes and their measures used as end points in systemic lupus erythematosus (SLE) patient care and clinical trials have been varied and are still evolving. Although significant reductions in morbidity and mortality in SLE have been achieved, the medications approved for SLE have remained the same during the ...

journal_title：Current rheumatology reports

authors： Jolly M

更新日期：2010-08-01 00:00:00

abstract：:Antiphospholipid syndrome is an important cause of neurologic morbidity. The clinical criteria for antiphospholipid syndrome include only cerebrovascular arterial and venous thrombosis, but many other neurologic manifestations have been associated with antiphospholipid antibodies (aPL). This review discusses the role ...

journal_title：Current rheumatology reports

authors： Roldan JF,Brey RL

更新日期：2007-05-01 00:00:00

abstract：:Neonatal lupus is a disease characterized by one or more of the following findings: congenital heart block, cardiomyopathy, cutaneous lupus lesions, hepatobiliary disease, and thrombocytopenia. Accumulating evidence indicates that the disease is probably caused by maternal autoantibodies, particularly autoantibodies o...

journal_title：Current rheumatology reports

authors： Lee LA

更新日期：2001-10-01 00:00:00

abstract：:Sleep disturbance is one of the most common comorbid problems for chronic pain patients. The association between the two phenomena has long been recognized, but the nature of the relationship is not well-understood. Many agree that the relationship is likely bidirectional. In this review, we focus on one side of the r...

journal_title：Current rheumatology reports

authors： Okifuji A,Hare BD

更新日期：2011-12-01 00:00:00

abstract：:Clinical evaluation of patients with low bone mass attempts to determine which patients should be offered one of the effective therapies for fracture prevention. Current guidelines are primarily based on bone density. Risk factors are used, but their contribution to fracture risk is not easily assessed. The combinatio...

journal_title：Current rheumatology reports

authors： Deal CL

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Polymyalgia rheumatica (PMR) is one of the most common inflammatory rheumatologic condition occurring in older adults. It is characterized by proximal pain and stiffness in the shoulders, neck, and/or pelvic girdle in individuals over 50 years of age along with evidence of an intense systemic infl...

journal_title：Current rheumatology reports

authors： Gazitt T,Zisman D,Gardner G

更新日期：2020-06-19 00:00:00

abstract：PURPOSE OF THE REVIEW:We will address current treatment and unmet needs in psoriatic arthritis (PsA), examine existing randomized controlled trials (RCTs), and consider options for new trial designs and challenges in their implementation. RECENT FINDINGS:While therapeutic options for PsA have rapidly increased, there ...

journal_title：Current rheumatology reports

authors： Ogdie A,Coates L

更新日期：2017-04-01 00:00:00

abstract：:The frequency of Takayasu's arteritis (TA) has been estimated to be 2.9 cases per 1 million people, with a female preponderance, although female-to-male ratio varies from different geographic areas. A high frequency of haplotype A24-B52-DR2 has been found in Japanese patients, without this association in other populat...

journal_title：Current rheumatology reports

authors： Fraga A,Medina F

更新日期：2002-02-01 00:00:00

abstract：:The pathogenic mechanisms in Behçet's syndrome are largely unknown. An autoantigen role for human leukocyte antigen B51 has been proposed. The reasons behind the thrombophilia are also not clear. Endothelial pathology could be the main culprit. The recently proposed association between familial Mediterranean fever and...

journal_title：Current rheumatology reports

authors： Yazici H

更新日期：2003-06-01 00:00:00

abstract：:Systemic vasculitis can affect practically any structure in or around the eye. Although the ocular presentations of vasculitic disease are highly variable and may be quite subtle, it is important for physicians to understand some of the basic concepts, critical findings, and potential significance of ocular signs and ...

journal_title：Current rheumatology reports

authors： Shepherd JB 3rd

更新日期：2003-04-01 00:00:00

abstract：:Ayurvedic medicine is the traditional medicine of India, which originated over 5,000 years ago. Parts of this alternative medical system have become increasingly popular worldwide as patients seek approaches to medical care that they perceive as more holistic and less toxic than those offered by conventional Western m...

journal_title：Current rheumatology reports

authors： Basnyat S,Kolasinski SL

更新日期：2014-08-01 00:00:00