Serotonin and aggression in children.

Abstract:

:Research consistently indicates that in animals and adults, reduced central serotonergic (5-HT) function is associated with increased aggression. This relationship has been elucidated via cerebrospinal fluid monoamine metabolite levels, hormonal responses to pharmacologic challenge using serotonergic probes, platelet receptor binding studies, and, more recently, through molecular genetic approaches. In contrast, studies examining the relationship of 5-HT to aggression in children have been characterized by inconsistent findings. The literature examining the relationship between central 5-HT function and aggression is reviewed. Several hypotheses that might account for the discrepancies in the child literature are examined.

journal_name

Curr Psychiatry Rep

authors

Mitsis EM,Halperin JM,Newcorn JH

doi

10.1007/s11920-000-0052-0

keywords:

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

95-101

issue

2

eissn

1523-3812

issn

1535-1645

journal_volume

2

pub_type

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