Pharmacotherapy for borderline personality disorder--current evidence and recent trends.

Abstract:

:Drug treatment of patients with borderline personality disorder (BPD) is common but mostly not supported by evidence from high-quality research. This review summarises the current evidence up to August 2014 and also aims to identify research trends in terms of ongoing randomised controlled trials (RCTs) as well as research gaps. There is some evidence for beneficial effects by second-generation antipsychotics, mood stabilisers and omega-3 fatty acids, while the overall evidence base is still unsatisfying. The dominating role SSRI antidepressants usually play within the medical treatment of BPD patients is neither reflected nor supported by corresponding evidence. Any drug treatment of BPD patients should be planned and regularly evaluated against this background of evidence. Research trends indicate increasing attention to alternative treatments such as dietary supplementation by omega-3 fatty acids or oxytocin.

journal_name

Curr Psychiatry Rep

authors

Stoffers JM,Lieb K

doi

10.1007/s11920-014-0534-0

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

534

issue

1

eissn

1523-3812

issn

1535-1645

journal_volume

17

pub_type

杂志文章,评审
  • Circadian Rhythms in Obsessive-Compulsive Disorder: Recent Findings and Recommendations for Future Research.

    abstract:PURPOSE OF REVIEW:Circadian rhythms are a topic of growing interest in mental health, particularly in obsessive-compulsive disorder. However, the consistency of this link has not been carefully examined. Thus, the present review integrates findings from the past 5 years in order to determine the strength of such a rela...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-019-1033-0

    authors: Cox RC,Olatunji BO

    更新日期:2019-06-04 00:00:00

  • The genetics of alcoholism and alcohol abuse.

    abstract::Twin studies have established that there are substantial genetic influences on alcoholism (0.5-0.6) in both men and women. Our knowledge of behaviors predisposing to alcoholism, including anxiety and impulsivity, is advancing rapidly through animal and human studies. Although alcoholism is often comorbid with other su...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-001-0012-3

    authors: Enoch MA,Goldman D

    更新日期:2001-04-01 00:00:00

  • Functional outcomes in schizophrenia: employment status as a metric of treatment outcome.

    abstract::The importance of an adequate and satisfying level of functioning for the course and outcome of schizophrenia has been increasingly emphasized by researchers in recent years. Employment status is a major component of the patient's functioning and is generally believed to be essential for well-being, satisfaction in li...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-012-0261-3

    authors: Schennach R,Musil R,Möller HJ,Riedel M

    更新日期:2012-06-01 00:00:00

  • Pain and depression: an integrative review of neurobiological and psychological factors.

    abstract::The comorbidity of pain and depression has been well established in the literature and is associated with a greater burden to the individual and society than either condition alone. The relationship between pain and depression is quite complex and multiple factors must be considered when trying to disentangle the pain...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-013-0421-0

    authors: Goesling J,Clauw DJ,Hassett AL

    更新日期:2013-12-01 00:00:00

  • Animal models of anxiety disorders.

    abstract::Animal models may be useful in investigating the fundamental mechanisms underlying psychiatric disorders, and may contribute to the development of new medications. A computerized literature search was used to collect studies on recently developed animal models for anxiety disorders. Particular cognitive-affective proc...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-003-0056-7

    authors: Uys JD,Stein DJ,Daniels WM,Harvey BH

    更新日期:2003-08-01 00:00:00

  • Nutrients, neurodevelopment, and mood.

    abstract::Human neurodevelopment is the result of genetic and environmental interactions. This paper examines the role of prenatal nutrition relative to psychiatric disorders and explores the relationship among nutrients, mood changes, and mood disorders. Epidemiologic studies have found that adults who were born with a normal,...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-004-0006-z

    authors: Casper RC

    更新日期:2004-12-01 00:00:00

  • Internet interventions for mental health and addictions: current findings and future directions.

    abstract::Over the last several years, there has been a substantial increase in the number of publications reporting on Internet interventions for mental health and addictions. This paper provides a summary of the recent research on Internet interventions for the most common mental health and addictions concerns-depression, anx...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-014-0521-5

    authors: Cunningham JA,Gulliver A,Farrer L,Bennett K,Carron-Arthur B

    更新日期:2014-12-01 00:00:00

  • Behavioral inhibition: a neurobiological perspective.

    abstract::Behavioral inhibition (BI) during early childhood has been associated with subsequent development of anxiety disorders. However, understanding of the neuroanatomical substrates of BI in humans generally has not kept pace with that of anxiety disorders. Recent interpretations and implementations of Gray's and Kagan's c...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-006-0062-7

    authors: Morgan BE

    更新日期:2006-08-01 00:00:00

  • Schizophrenia and genetics: new insights.

    abstract::There is consistent evidence that the principal etiology of schizophrenia involves predisposing genetic factors. Recent years have seen several new insights in the genetics of schizophrenia. Several chromosomal regions show significant evidence that they contain schizophrenia susceptibility genes. A clinically relevan...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-996-0051-x

    authors: Bassett AS,Chow EW,Weksberg R,Brzustowicz L

    更新日期:2002-08-01 00:00:00

  • Acute treatment of mania: an update on new medications.

    abstract::Acute mania is frequently a medical emergency requiring hospitalization for behavioral control, rapid resolution of irritability, agitation, de-escalation of mood, and decreasing of risk-taking behavior. Lithium efficacy in the management of acute mania was reported in 1949 and approved by the US Food and Drug Adminis...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-006-0058-3

    authors: Gajwani P,Kemp DE,Muzina DJ,Xia G,Gao K,Calabrese JR

    更新日期:2006-12-01 00:00:00

  • Marijuana and Bariatric Surgery.

    abstract:PURPOSE OF REVIEW:Marijuana use presents a unique challenge to bariatric surgery programs. We review the recent evidence examining marijuana use on outcomes following bariatric surgery. RECENT FINDINGS:Recent studies have not demonstrated an increased risk of short-term surgical complications or differences in up to 2...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-020-01218-4

    authors: Diggins A,Heinberg L

    更新日期:2021-01-12 00:00:00

  • Recent developments in child and adolescent social phobia.

    abstract::The following article discusses research trends in childhood and adolescent social phobia during the past year. Of particular importance are findings regarding prevalence rates, cognitive variables and social skills deficits, temperamental influences, and the use of selective serotonin reuptake inhibitors (SSRIs). Rec...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-000-0080-9

    authors: Chavira DA,Stein MB

    更新日期:2000-08-01 00:00:00

  • Adolescent Substance Use Disorder Treatment: an Update on Evidence-Based Strategies.

    abstract:PURPOSE OF REVIEW:To examine the most recent published evidence (2016-2019) regarding the treatment of adolescent substance use disorders and to provide an update on evidence-based strategies, adjunctive interventions, and methods to improve currently established treatment approaches. RECENT FINDINGS:Recent evidence s...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-019-1086-0

    authors: Fadus MC,Squeglia LM,Valadez EA,Tomko RL,Bryant BE,Gray KM

    更新日期:2019-09-14 00:00:00

  • The Surgeon General's National Action Agenda on Children's Mental Health.

    abstract::The Surgeon General's National Action Agenda highlighted key issues that challenge the public health system in appropriately meeting the mental health needs of children and their families. Among these issues included the need for screening and early identification, improving access to appropriate mental health care, s...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章

    doi:10.1007/s11920-002-0042-5

    authors: Olin SC,Hoagwood K

    更新日期:2002-04-01 00:00:00

  • Antiepileptic drugs for the treatment of post-traumatic stress disorder.

    abstract::Post-traumatic stress disorder (PTSD) is a disruptive, chronic, and relatively common disorder that is often difficult to treat. Many patients with PTSD are unresponsive, have only moderate or marginal responses, or have troubling side effects to first-line serotonin reuptake inhibitor treatment. Studies suggest that ...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-007-0035-5

    authors: Berlin HA

    更新日期:2007-08-01 00:00:00

  • Cannabis and Psychosis: a Critical Overview of the Relationship.

    abstract::Interest in the relationship between cannabis use and psychosis has increased dramatically in recent years, in part because of concerns related to the growing availability of cannabis and potential risks to health and human functioning. There now exists a plethora of scientific articles addressing this issue, but few ...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-015-0657-y

    authors: Ksir C,Hart CL

    更新日期:2016-02-01 00:00:00

  • Genetic advances in autism hinge on the method of measuring symptoms.

    abstract::Advances in genotyping and related technologies and the study of families with two or more autistic siblings have allowed the reporting of various genetic linkage and candidate gene association studies for autism. Despite this significant research effort, there still is no general agreement on the role of particular g...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-005-0010-y

    authors: Todd RD

    更新日期:2005-04-01 00:00:00

  • Insomnia as a Precipitating Factor in New Onset Mental Illness: a Systematic Review of Recent Findings.

    abstract:PURPOSE:We aimed to systematically review recent publications (01/2014-03/2017) with longitudinal designs allowing for the assessment of the prospective risk of insomnia on new onset mental illness in key conditions: anxiety, depression, bipolar disorder, posttraumatic stress disorder, substance use disorders, and suic...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-017-0802-x

    authors: Pigeon WR,Bishop TM,Krueger KM

    更新日期:2017-08-01 00:00:00

  • New findings from the Bipolar Collaborative Network: clinical implications for therapeutics.

    abstract::In this article, we highlight recent Bipolar Collaborative Network data. We found that childhood-onset bipolar illness is common, often goes untreated for more than a decade, and carries a poor prognosis. During randomized studies of adjunctive medications in depression: 1) Venlafaxine showed higher switch rates than ...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-006-0056-5

    authors: Post RM,Altshuler LL,Frye MA,Suppes T,McElroy S,Keck PE Jr,Leverich GS,Kupka R,Nolen WA,Grunze H

    更新日期:2006-12-01 00:00:00

  • Towards Precision Addiction Treatment: New Findings in Co-morbid Substance Use and Attention-Deficit Hyperactivity Disorders.

    abstract::Attention-deficit hyperactivity disorder (ADHD) and substance use disorders (SUDs) may have common etiologies. ADHD is more prevalent in patients with substance use disorders, and this pattern is consistent across different substances of abuse. Individuals with SUDs and ADHD exhibit significant variations in their cli...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-017-0769-7

    authors: Luo SX,Levin FR

    更新日期:2017-03-01 00:00:00

  • Historical studies of premenstrual tension up to 30 years ago: implications for future research.

    abstract::The biology and treatment of premenstrual tension syndrome has advanced significantly in the past 30 years. Newer research expands on earlier literature that has been accumulated before 1972. This review selectively considers this earlier literature, because it defines the nature and impact of what was then considered...

    journal_title:Current psychiatry reports

    pub_type: 历史文章,杂志文章

    doi:10.1007/s11920-002-0068-8

    authors: Janowsky DS,Rausch JL,Davis JM

    更新日期:2002-12-01 00:00:00

  • Recent advances in research on cognition and emotion in OCD: a review.

    abstract::The cognitive model of OCD suggests that misinterpreting intrusive thoughts as unacceptable leads to increased anxiety and attempts to suppress or ignore the thoughts through avoidance or compulsive rituals. An insidious negative feedback loop develops as one's attention focuses on these thoughts and in turn the unwan...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-013-0357-4

    authors: Calkins AW,Berman NC,Wilhelm S

    更新日期:2013-05-01 00:00:00

  • The cost-effectiveness of substance abuse treatment.

    abstract::Researchers have estimated the cost of treating substance abuse and its effects on medical care and social service expenses, but have rarely used the methods developed to evaluate medical care interventions. When outcomes are expressed as quality-adjusted life years, substance abuse treatment may be compared with othe...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-999-0027-8

    authors: Barnett PG

    更新日期:1999-12-01 00:00:00

  • Bipolar disorder in late life: future directions in efficacy and effectiveness research.

    abstract::There is a dearth of knowledge regarding the diagnosis and treatment of bipolar disorder in late life. Based on a review of the current research on bipolar disorder in late life, emerging areas of research were identified: 1) methodological challenges in diagnosing bipolar disorder; 2) a lack of guidelines for the tre...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-005-0018-3

    authors: Kilbourne AM

    更新日期:2005-03-01 00:00:00

  • Animal models of stress vulnerability and resilience in translational research.

    abstract::Stress has been identified as a key risk factor for a multitude of human pathologies. However, stress by itself is often not sufficient to induce a disease, as a large contribution comes from an individual's genetic background. Therefore, many stress models have been created to investigate this so-called gene-environm...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-012-0256-0

    authors: Scharf SH,Schmidt MV

    更新日期:2012-04-01 00:00:00

  • Moving to Beat Anxiety: Epidemiology and Therapeutic Issues with Physical Activity for Anxiety.

    abstract:PURPOSE OF REVIEW:The purpose of this paper was to provide a comprehensive narrative review of the relationship between physical activity (PA) and anxiety and the rationale for including it as a treatment option for anxiety disorders. Several gaps in the literature are highlighted alongside recommendations for future r...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-018-0923-x

    authors: Kandola A,Vancampfort D,Herring M,Rebar A,Hallgren M,Firth J,Stubbs B

    更新日期:2018-07-24 00:00:00

  • Recent advances in structural and functional brain imaging studies of attention-deficit/hyperactivity disorder.

    abstract::The field of neuroimaging of attention-deficit/hyperactivity disorder (ADHD) is now 30 years old. This brief selective review highlights the increasing sophistication of recent structural and functional neuroimaging studies of ADHD. In volumetric studies, investigators are examining extra-frontal, as well as frontal-s...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-007-0052-4

    authors: Kelly AM,Margulies DS,Castellanos FX

    更新日期:2007-10-01 00:00:00

  • Artificial Intelligence for Mental Health and Mental Illnesses: an Overview.

    abstract:PURPOSE OF REVIEW:Artificial intelligence (AI) technology holds both great promise to transform mental healthcare and potential pitfalls. This article provides an overview of AI and current applications in healthcare, a review of recent original research on AI specific to mental health, and a discussion of how AI can s...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-019-1094-0

    authors: Graham S,Depp C,Lee EE,Nebeker C,Tu X,Kim HC,Jeste DV

    更新日期:2019-11-07 00:00:00

  • Sex Differences in Anxiety Disorders in Older Adults.

    abstract:PURPOSE OF REVIEW:Anxiety disorders are the most prevalent mental disorders. Although prevalence estimates are lower in males than females, the disability associated with anxiety disorders has been increasing in males. This review focuses on recent research studying sex differences in anxiety disorders and associated s...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-020-01203-x

    authors: Vasiliadis HM,Desjardins F,Roberge P,Grenier S

    更新日期:2020-10-30 00:00:00

  • Epidemiological and Clinical Gender Differences in OCD.

    abstract:PURPOSE OF REVIEW:This review highlights recent research regarding gender differences in OCD, with a focus on prevalence, course of illness, symptom presentation, comorbidity, and treatment response. RECENT FINDINGS:Overall, findings remain mixed. OCD may be more common among males in childhood, but is more common amo...

    journal_title:Current psychiatry reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11920-019-1015-2

    authors: Mathes BM,Morabito DM,Schmidt NB

    更新日期:2019-04-23 00:00:00