Genetic advances in autism hinge on the method of measuring symptoms.

Abstract:

:Advances in genotyping and related technologies and the study of families with two or more autistic siblings have allowed the reporting of various genetic linkage and candidate gene association studies for autism. Despite this significant research effort, there still is no general agreement on the role of particular genes that predispose to the risk of autism. One source of general debate is whether core symptoms studied in research on the heredity of autism include single or multiple independent genetic domains. In this review, it is argued that failure to control for co-existing dimensions of psychopathology and lack of assessment of parents may lead to misinterpretation of genetic findings from pedigrees involving multiple affected family members.

journal_name

Curr Psychiatry Rep

authors

Todd RD

doi

10.1007/s11920-005-0010-y

keywords:

subject

Has Abstract

pub_date

2005-04-01 00:00:00

pages

133-7

issue

2

eissn

1523-3812

issn

1535-1645

journal_volume

7

pub_type

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