Abstract:
:The eating disorders anorexia nervosa (AN) and bulimia nervosa (BN) are severe psychiatric disorders with high mortality. Our knowledge about the neurobiology of eating disorders is very limited, and the question remains whether alterations in brain structure or function in eating disorders are state related, remnants of the illness or premorbid traits. The brain reward system is a relatively well-characterized brain circuitry that plays a central role in the drive to eat and individuals with current or past eating disorders showed alterations in those pathways compared to controls. Here we propose that structural and functional alterations in the insula and frontal cortex, including orbitofrontal and cingulate regions, areas that contribute to reward and anxiety processing, could predispose to developing an eating disorder and that adaptive changes in those circuits in response to malnutrition or repeated binge eating and purging could further promote illness behavior, hinder recovery and contribute to relapse.
journal_name
Curr Psychiatry Repjournal_title
Current psychiatry reportsauthors
Frank GKdoi
10.1007/s11920-013-0396-xsubject
Has Abstractpub_date
2013-10-01 00:00:00pages
396issue
10eissn
1523-3812issn
1535-1645journal_volume
15pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:We review recent empirical investigations about two core processes subtending impairments in interpersonal functioning and, more precisely, cooperative behaviors in personality disorders: Trust toward others and rejection sensitivity. The main contributions are about borderline and narcissistic person...
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pub_type: 杂志文章,评审
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journal_title:Current psychiatry reports
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-016-0732-z
更新日期:2016-10-01 00:00:00
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journal_title:Current psychiatry reports
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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journal_title:Current psychiatry reports
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2010-12-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2019-03-22 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2008-02-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2006-12-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-008-0037-y
更新日期:2008-06-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2004-06-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2001-02-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2004-12-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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更新日期:2018-04-07 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-011-0175-5
更新日期:2011-04-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2013-05-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 历史文章,杂志文章
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更新日期:2002-12-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2010-12-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2009-10-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2016-12-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-016-0710-5
更新日期:2016-08-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2010-10-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-014-0541-1
更新日期:2015-02-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2016-08-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2009-12-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2014-12-01 00:00:00
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journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
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更新日期:2005-03-01 00:00:00