Abstract:
:Attention-deficit/hyperactivity disorder (ADHD) is a heterogeneous disorder characterized by inattention, impulsivity, and/or hyperactivity in children and adults. Putative environmental risk factors for ADHD include toxin and prenatal smoke exposure, low socioeconomic status, and parental marital instability and discord. Genetic associations with ADHD have been found in the dopaminergic, serotonergic, and noradrenergic neurotransmitter systems, but findings are inconsistent across studies. Herein, we review studies of gene-environment interactions for ADHD to better understand how genetic and environmental risk factors may contribute to the disorder in a nonindependent fashion, which may account in part for the inconsistent findings on genetic associations. Although evidence of interactions between prenatal substance exposure and the dopamine genes DAT1 and DRD4 was found, findings across studies have been mixed. We discuss these findings and the future directions and limitations of current gene-environment research.
journal_name
Curr Psychiatry Repjournal_title
Current psychiatry reportsauthors
Ficks CA,Waldman IDdoi
10.1007/s11920-009-0058-1subject
Has Abstractpub_date
2009-10-01 00:00:00pages
387-92issue
5eissn
1523-3812issn
1535-1645journal_volume
11pub_type
杂志文章,评审abstract::Post-traumatic stress disorder (PTSD) is a disruptive, chronic, and relatively common disorder that is often difficult to treat. Many patients with PTSD are unresponsive, have only moderate or marginal responses, or have troubling side effects to first-line serotonin reuptake inhibitor treatment. Studies suggest that ...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-007-0035-5
更新日期:2007-08-01 00:00:00
abstract::The biology and treatment of premenstrual tension syndrome has advanced significantly in the past 30 years. Newer research expands on earlier literature that has been accumulated before 1972. This review selectively considers this earlier literature, because it defines the nature and impact of what was then considered...
journal_title:Current psychiatry reports
pub_type: 历史文章,杂志文章
doi:10.1007/s11920-002-0068-8
更新日期:2002-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Sex differences in cognitive function are well documented yet few studies had adequate numbers of women and men living with HIV (WLWH; MLWH) to identify sex differences in neurocognitive impairment (NCI) and the factors contributing to NCI. Here, we review evidence that WLWH may be at greater risk for...
journal_title:Current psychiatry reports
pub_type: 杂志文章
doi:10.1007/s11920-019-1089-x
更新日期:2019-09-14 00:00:00
abstract::Researchers have estimated the cost of treating substance abuse and its effects on medical care and social service expenses, but have rarely used the methods developed to evaluate medical care interventions. When outcomes are expressed as quality-adjusted life years, substance abuse treatment may be compared with othe...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-999-0027-8
更新日期:1999-12-01 00:00:00
abstract::The present review examines the moderating role of ideology on the effects of war, armed conflict, and terrorism on youth. Ideology is an important factor given the central role played by religio-political ideology and nationalism in present-day conflicts. Ideologies or worldviews represent cognitive frameworks that i...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-016-0684-3
更新日期:2016-05-01 00:00:00
abstract:PURPOSE OF REVIEW:This review provides an overview of the state of research on alliance ruptures and resolutions in the treatment of personality disorders (PDs). We discuss frequently used instruments to measure alliance ruptures and resolutions. We discuss the effectiveness of rupture resolution processes and highligh...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-020-01212-w
更新日期:2020-12-11 00:00:00
abstract::By design or by default, primary care providers (PCPs)are frequently the vanguard in the fight against suicide. Recent studies have highlighted programs to improve screening and prevention of suicidality in the medical home, particularly among high-risk patients, such as adolescents, the elderly, and veterans. Increas...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-012-0286-7
更新日期:2012-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Sex differences in the epidemiology and clinical presentation of trauma-related psychopathology have long been documented. Multiple underlying mechanisms have been examined, both psychosocial and biological. Among the most promising biological mechanisms are neural substrates of trauma-related psychop...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-017-0854-y
更新日期:2017-11-08 00:00:00
abstract::Frontotemporal dementia (FTD) is a clinically distinct disorder that is under-recognized. A primary focus of recent research has been to delineate neuropsychiatric features that best discriminate FTD from other dementias, and to identify test instruments that elicit differentiating characteristics most effectively. Ad...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-999-0015-z
更新日期:1999-10-01 00:00:00
abstract::The perinatal period introduces a myriad of changes. One important but often overlooked change is an increased reporting of sleep disturbance. Although casually regarded as a consequence of pregnancy or postpartum, there is emerging evidence implicating significant sleep disturbance, characterized by insomnia symptoms...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-016-0705-2
更新日期:2016-07-01 00:00:00
abstract::Updated findings on the relationship between nicotine and depression are presented. Clinical and preclinical research on nicotine use and depression suggests that nicotine may have some properties in common with antidepressants. Updated findings involve the comorbidity of smoking and major depressive disorder (MDD), t...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-001-0040-z
更新日期:2001-12-01 00:00:00
abstract::The human gut harbors a complex community of microbes that profoundly influence many aspects of growth and development, including development of the nervous system. Advances in high-throughput DNA sequencing methods have led to rapidly expanding knowledge about this gut microbiome. Here, we review fundamental emerging...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-012-0337-0
更新日期:2013-02-01 00:00:00
abstract::Human neurodevelopment is the result of genetic and environmental interactions. This paper examines the role of prenatal nutrition relative to psychiatric disorders and explores the relationship among nutrients, mood changes, and mood disorders. Epidemiologic studies have found that adults who were born with a normal,...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-004-0006-z
更新日期:2004-12-01 00:00:00
abstract::Drug treatment of patients with borderline personality disorder (BPD) is common but mostly not supported by evidence from high-quality research. This review summarises the current evidence up to August 2014 and also aims to identify research trends in terms of ongoing randomised controlled trials (RCTs) as well as res...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-014-0534-0
更新日期:2015-01-01 00:00:00
abstract::Ethical issues in the field of schizophrenia research have become a focus of intense debate in the past year. The publication of the final report of the National Bioethics Advisory Commission (NBAC) coupled with recent media reports have catapulted these issues into international view. Major questions have been raised...
journal_title:Current psychiatry reports
pub_type: 杂志文章
doi:10.1007/s11920-999-0005-1
更新日期:1999-10-01 00:00:00
abstract::HIV, the cause of AIDS, has infected more than 65 million people worldwide, including 1 million children. An estimated 39.5 million people are living with HIV. As of 2006, 4.3 million were newly infected, with 2.8 million occurring in sub-Saharan Africa. Rates of infection have risen more than 50% in Eastern Europe an...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-008-0020-7
更新日期:2008-04-01 00:00:00
abstract::Behavioral inhibition (BI) during early childhood has been associated with subsequent development of anxiety disorders. However, understanding of the neuroanatomical substrates of BI in humans generally has not kept pace with that of anxiety disorders. Recent interpretations and implementations of Gray's and Kagan's c...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-006-0062-7
更新日期:2006-08-01 00:00:00
abstract::The potential role of personality disorders in understanding husband violence is a controversial issue. Although researchers consistently find high rates of personality disorders, particularly antisocial and borderline characteristics, among samples of male batterers, feminist theorists worry that such research will d...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-002-0006-9
更新日期:2002-02-01 00:00:00
abstract:PURPOSE OF REVIEW:We review evidence for the potential importance of interoception, i.e., the processing of signals arising from inside the body, for deficient psychosocial functioning in borderline personality disorder (BPD). RECENT FINDINGS:Evidence suggests that variability in interoception interacts with higher-or...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-018-0890-2
更新日期:2018-03-28 00:00:00
abstract::Bipolar depression is considered the most difficult-to-treat phase of bipolar disorder, in relation to its pervasiveness and efficacy and/or tolerability limitations of available treatments. Indeed, most mood stabilizers and atypical antipsychotics are not as effective in ameliorating depressive compared with manic sy...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-013-0378-z
更新日期:2013-08-01 00:00:00
abstract::Electroconvulsive therapy (ECT) is a safe and effective treatment for severe mood disorders. Rarely there can be serious complications, such as postictal agitation, cardiovascular compromise, prolonged seizures, and status epilepticus, all of which are important for the clinician to recognize and treat. Postictal agit...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-008-0076-4
更新日期:2008-12-01 00:00:00
abstract::Bipolar disorder is marked by frequent recurrences, a course from childhood or early adulthood until death, marked increased rates of suicide, and substantial functional morbidity. Maintenance treatment is generally recommended to reduce the ravages of the illness. This article reviews the evidence that lithium, dival...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-000-0007-5
更新日期:2000-12-01 00:00:00
abstract:PURPOSE OF REVIEW:We review recent research addressing neurocognitive and information processing abnormalities in posttraumatic stress disorder (PTSD), including studies informing direction of causality. We additionally consider neurocognition in the context of co-morbid mild traumatic brain injury (TBI) and psychosoci...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-018-0964-1
更新日期:2018-09-17 00:00:00
abstract::Puerperal psychoses do not represent a nosological entity, but rather a selection of puerperally triggered "ordinary" functional psychoses with cycloid psychoses predominating and schizophrenias occurring very rarely. The prognosis is basically favorable concerning symptom remission and social and occupational functio...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-002-0025-6
更新日期:2002-06-01 00:00:00
abstract::This review discusses suicide warning signs in clinical practice and has three simple goals: 1) to help practitioners differentiate in a clinically meaningful fashion between warning signs and risk factors for suicide; 2) to articulate the link among warning signs for suicide, hopelessness, and intent to die; and 3) t...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-008-0015-4
更新日期:2008-02-01 00:00:00
abstract::Viral encephalitis, a condition in which a virus infects the brain and produces an inflammatory response, affects approximately 20,000 individuals per year in the United States. The viral encephalidities include sporadic and epidemic acute viral encephalidities and subacute and chronic/progressive viral encephalitis o...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-004-0024-x
更新日期:2004-10-01 00:00:00
abstract::Over the last several years, there has been a substantial increase in the number of publications reporting on Internet interventions for mental health and addictions. This paper provides a summary of the recent research on Internet interventions for the most common mental health and addictions concerns-depression, anx...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-014-0521-5
更新日期:2014-12-01 00:00:00
abstract::The cognitive model of OCD suggests that misinterpreting intrusive thoughts as unacceptable leads to increased anxiety and attempts to suppress or ignore the thoughts through avoidance or compulsive rituals. An insidious negative feedback loop develops as one's attention focuses on these thoughts and in turn the unwan...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-013-0357-4
更新日期:2013-05-01 00:00:00
abstract::Cognitive-behavioral therapy (CBT) for obsessive-compulsive disorder (OCD) has been shown to be a highly effective treatment for children and adults. In the current review, we briefly describe the historical developments of the treatment, and recent findings related to five areas of inquiry: 1) Does intensity of CBT i...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-005-0080-x
更新日期:2005-08-01 00:00:00
abstract::Substance use disorder is a chronic condition of compulsive drug seeking and use that is mediated by stable changes in central reward pathways. Repeated use of abused drugs causes persistent alterations in gene expression responsible for the long-term behavioral and structural changes. Recently, it has been suggested ...
journal_title:Current psychiatry reports
pub_type: 杂志文章,评审
doi:10.1007/s11920-010-0099-5
更新日期:2010-04-01 00:00:00