The gut microbiome: a new frontier in autism research.

Abstract:

:The human gut harbors a complex community of microbes that profoundly influence many aspects of growth and development, including development of the nervous system. Advances in high-throughput DNA sequencing methods have led to rapidly expanding knowledge about this gut microbiome. Here, we review fundamental emerging data on the human gut microbiome, with a focus on potential interactions between the microbiome and autism spectrum disorders (ASD) and consider research on atypical patterns of feeding and nutrition in ASD and how they might interact with the microbiome. Finally we selectively survey results from studies in rodents on the impact of the microbiome on neurobehavioral development. The evidence reviewed here suggests that a deeper understanding of the gut microbiome could open up new avenues of research on ASD, including potential novel treatment strategies.

journal_name

Curr Psychiatry Rep

authors

Mulle JG,Sharp WG,Cubells JF

doi

10.1007/s11920-012-0337-0

subject

Has Abstract

pub_date

2013-02-01 00:00:00

pages

337

issue

2

eissn

1523-3812

issn

1535-1645

journal_volume

15

pub_type

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