Coordinate regulation of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 expression in human vascular smooth muscle cells.

abstract：:A transmission electron microscope study of carbonate apatite crystals isolated from bone and mineralizing tendon, as well as those produced synthetically under approximated-physiological conditions, shows that they are thin irregular shaped plates. Electron diffraction patterns of individual crystals confirm that the...

journal_title：Connective tissue research

authors： Moradian-Oldak J,Weiner S,Addadi L,Landis WJ,Traub W

更新日期：1991-01-01 00:00:00

abstract：PURPOSE/AIM:Glutamate is one of the signaling molecules responsible for transmission in the central nervous system. Periodontal ligament (PDL) cells were recently reported to express metabotropic glutamate receptors (mGluRs). However, the functions of mGluR signaling in PDL cells or PDL-related cells remain largely unk...

journal_title：Connective tissue research

authors： Kanaya S,Komatsu H,Shimauchi H,Nemoto E

更新日期：2016-09-01 00:00:00

abstract：:The interaction of sodium dodecyl sulfate with elastin has been studied by complexometric titration. Approximately 1.2 mumoles of protons with a pKapp of 5.45 are taken up by 10 milligrams of insoluble elastin upon the binding of detergent, apparently due to the protonation of normally ionized carboxylate functions in...

journal_title：Connective tissue research

authors： Kagan HM

更新日期：1978-01-01 00:00:00

abstract：:Effects of applied hydrostatic pressure on transmembrane potentials were investigated in sheep articular chondrocytes and human skin fibroblasts in non-confluent monolayer cultures. Resting potentials in chondrocytes (about -12 mv) and in fibroblasts (about -15 mV) were increased and decreased respectively by over 40%...

journal_title：Connective tissue research

authors： Wright MO,Stockwell RA,Nuki G

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:Excessive apoptosis plays an important role in the progression of intervertebral disc degeneration. However, the effect of autophagy, another type of programmed cell death, on the pathogenesis of disc degeneration is still unclear. Macroautophagy and chaperone-mediated autophagy (CMA) change and intervertebra...

journal_title：Connective tissue research

authors： Ye W,Xu K,Huang D,Liang A,Peng Y,Zhu W,Li C

更新日期：2011-01-01 00:00:00

abstract：:The paper reviews the changes in ameloblast ultrastructure, concomitant with the changes in its functions across the major stages of amelogenesis. It describes the mechanisms associated with the major events in biosynthesis and degradation of the major enamel proteins (amelogenins and tuftelin/enamelins) and with the ...

journal_title：Connective tissue research

authors： Deutsch D,Catalano-Sherman J,Dafni L,David S,Palmon A

更新日期：1995-01-01 00:00:00

abstract：:An agarose gel matrix was utilized to grow chondrocytes from human donors of various ages in cell culture. The chondrocytes produced the pericellular matrix characteristic for such cells and synthesized collagen type II as well as glyco-saminoglycans. The latter exhibit the typical distribution pattern of the respecti...

journal_title：Connective tissue research

authors： Delbrück A,Dresow B,Gurr E,Reale E,Schröder H

更新日期：1986-01-01 00:00:00

abstract：:Elastic ear cartilage and aortae from nine-day-old hamsters were incubated in Krebs-Ringer medium containing ascorbate, beta-aminopropionitrile and either [14C]proline or [3H]valine. The [14C]proline-labeled proteins were separated by chromatography on Agarose A-5 m in sodium dodecyl sulfate and their [14C]-hydroxypro...

journal_title：Connective tissue research

authors： Heeger P,Rosenbloom J

更新日期：1980-01-01 00:00:00

abstract：:Hyperhomocysteinemia causes connective tissue pathology. Several theories on the mechanism of homocysteine toxicity in connective tissue are reviewed briefly. A possible new mechanism was revealed recently in the discovery of a reaction in which homocysteine thiolactone is converted to mercaptopropionaldehyde. The rea...

journal_title：Connective tissue research

authors： Toohey JI

更新日期：2008-01-01 00:00:00

abstract：:The purpose of this study was to examine the hypoxic and inflammatory conditions after immobilization in the joint capsule of rat knees. The unilateral knee joints of adult male rats were immobilized with an internal fixator (Im group) for 1 day, 3 days, and 1, 2, 4, 8, and 16 weeks. Sham-operated animals had holes dr...

journal_title：Connective tissue research

authors： Yabe Y,Hagiwara Y,Suda H,Ando A,Onoda Y,Tsuchiya M,Hatori K,Itoi E

更新日期：2013-01-01 00:00:00

abstract：:The interaction of elastin and microfibrils in elastogenesis in vitro was investigated with electron microscopy and immunohistochemistry. Fetal human pulmonary fibroblasts were cultured with or without beta-aminopropionitrile (BAPN). One week after seeding, the extracellular microfibrils were loosely arranged without ...

journal_title：Connective tissue research

authors： Fukuda Y,Nakazawa N,Yamanaka N

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:Treatment of meniscal injury is important for osteoarthritis (OA) prevention. Meniscus cells are divided between inner and outer cells, which have different characteristics and vascularity. We evaluated the effects of hyaluronic acid (HA) on the proliferation and migration of human inner and outer meniscus cell...

journal_title：Connective tissue research

authors： Murakami T,Otsuki S,Okamoto Y,Nakagawa K,Wakama H,Okuno N,Neo M

更新日期：2019-03-01 00:00:00

abstract：:Primary chondrocytes cultured in agarose can escape the gel, accumulate at the interface between agarose and the culture medium, and form an outgrowing tissue. These outgrowths can appear as voluminous cartilage-like nodules that have never been previously investigated. In the present study, bovine articular chondrocy...

journal_title：Connective tissue research

authors： Tran-Khanh N,Chevrier A,Lascau-Coman V,Hoemann CD,Buschmann MD

更新日期：2010-06-01 00:00:00

abstract：:Stimulation of the cholinergic inflammatory pathway can attenuate collagen-induced arthritis (CIA) and inhibit synovitis by Janus kinase (JAK) 2 and signal transducer and activator of transcription (STAT) 3 signaling. Suppressor of cytokine signaling (SOCS) protein can also regulate the inflammatory processes and acti...

journal_title：Connective tissue research

authors： Li T,Wu S,Li S,Bai X,Luo H,Zuo X

更新日期：2018-05-01 00:00:00

abstract：:The protein components of biomineralized structures (matrix proteins) are believed to modulate crystal nucleation and growth, and thereby influence the shape and strength of the final structure. The chicken eggshell contains a complex array of distinct matrix proteins. One of these was found to have similar molecular ...

journal_title：Connective tissue research

authors： Hincke MT

更新日期：1995-01-01 00:00:00

abstract：:Growth factors were historically defined as molecules produced by the body to regulate cell growth and proliferation. After the identification of their receptors and the intracellular signaling machinery they activate, it is now clear that they are involved in the regulation of multiple processes essential for develop...

journal_title：Connective tissue research

authors： Oehrl W,Panayotou G

更新日期：2008-01-01 00:00:00

abstract：:Fitting children and infants who have osteogenesis imperfecta (OI) with braces has posed substantial problems of implementation and patient management For the past twelve years bracing has been an important component of a patient research and management program conducted at the National Institutes of Health. By using ...

journal_title：Connective tissue research

authors： Weintrob JC

更新日期：1995-01-01 00:00:00

abstract：:Bone and dentin contain many phosphoproteins in their extracellular matrix. It has been postulated that the anionic character of these proteins, and the presence of phosphate groups in particular, is important for various functions related to biomineralization. Phosphophoryns (PP), are the most highly phosphorylated d...

journal_title：Connective tissue research

authors： Sfeir C,Veis A

更新日期：1996-01-01 00:00:00

abstract：:We determined the feasibility of using scaffolds of adenoviral human BMP2 gene (AdBMP2)-modified human bone marrow mesenchymal stem cells (hBMSCs) and antigen-free bovine cancellous bone (BCB) to construct bone tissue. hMSCs were infected with AdBMP-2. Expression of BMP-2 and alkaline phosphatase confirmed successful ...

journal_title：Connective tissue research

authors： Han D,Li J,Guan X

更新日期：2010-08-01 00:00:00

abstract：:Of more than 2 million segmental bone defects repaired annually with bone autografts and allografts, 15-40% fail. Improving healing rates may be approached with tissue engineering and use of periosteum overlying an allograft. The present study documents gene expression in human periosteum-allograft constructs compared...

journal_title：Connective tissue research

authors： Kemppainen J,Yu Q,Alexander J,Jacquet R,Scharschmidt T,Landis W

更新日期：2014-08-01 00:00:00

abstract：:Large joint arthrofibrosis and scarring, involving the shoulder, elbow, hip, and knee, can result in the loss of function and immobility. The pathway of joint contracture formation is still being elucidated and is due to aberrations in collagen synthesis and misorientation of collagen fibrils. Novel antibodies are bei...

journal_title：Connective tissue research

authors： Chen AF,Lee YS,Seidl AJ,Abboud JA

更新日期：2019-01-01 00:00:00

abstract：:The eggshell is an highly ordered structure deposited in the distal oviduct and composed of calcium carbonate and an organic matrix which is believed to influence its fabric. We have identified ovotransferrin as an 80 kDa matrix protein observed at high concentration in the uterine fluid at the initial stage of shell ...

journal_title：Connective tissue research

authors： Gautron J,Hincke MT,Panheleux M,Garcia-Ruiz JM,Boldicke T,Nys Y

更新日期：2001-01-01 00:00:00

abstract：:Solutions of type I acid soluble collagen were studied in light and electron microscopy at concentrations over 40 mg/ml. Banded patterns spontaneously emerge in samples observed between crossed polars between slide and coverslip. The textures are interpreted as precholesteric, appearing at the transition between the i...

journal_title：Connective tissue research

authors： Giraud-Guille MM,Besseau L

更新日期：1998-01-01 00:00:00

abstract：:Recently our laboratory has reported, in a lacerated flexor tendon model, that the "early turnover" phase of the repair process extends for a longer period of time in vivo than previously documented. The extensive turnover of the collagenous matrix was consistent with the presence of collagenolytic activity in repairi...

journal_title：Connective tissue research

authors： Russell JE,Manske PR

更新日期：1989-01-01 00:00:00

abstract：:Radiation therapy is one of the routine treatment modalities for cancer patients. Ionizing radiation (IR) can induce bone loss, and consequently increases the risk of fractures with delayed and nonunion of the bone in the cancer patients who receive radiotherapy. The orchestrated bone remodeling can be disrupted due t...

journal_title：Connective tissue research

authors： Zhang J,Qiu X,Xi K,Hu W,Pei H,Nie J,Wang Z,Ding J,Shang P,Li B,Zhou G

更新日期：2018-11-01 00:00:00

abstract：:The critical remembrance of my research activity displays aspects of inconsequence and mental rigidity. Particular probative examples are called to mind. Unpublished observations concerning immortalized dental cells are summarized. As a consequence, if I could start again, I would improve several aspects of my behavio...

journal_title：Connective tissue research

authors： Ruch JV

更新日期：2002-01-01 00:00:00

abstract：:In our previous developmental study on skin we reported that correlations existed between the collagen fibril diameter distribution, glycosaminoglycan content and composition, and mechanical role. In this work we present new but related electron microscope data on the ultrastructure of skins from flounder, marlin, cod...

journal_title：Connective tissue research

authors： Craig AS,Eikenberry EF,Parry DA

更新日期：1987-01-01 00:00:00

abstract：:The composition of glycosaminoglycans (GAGs) was analyzed in skin samples of eight patients suffering from localized scleroderma, i.e., three having generalized morphoea and five localized morphoea plaques. From each patients, biopsies were obtained from sclerotic and perilesional areas, and from clinically uninvolved...

journal_title：Connective tissue research

authors： Møller R,Serup J,Ammitzbøll T

更新日期：1985-01-01 00:00:00

abstract：:The desmoplastic response to breast carcinoma is being studied. The stimulation of stromal cell proliferation by a preformed breast tumor matrix was shown. An additional mechanism for stimulating scleroprotein deposition is described here. On a per-cell basis, the synthesis of collagen and elastin was increased by 50%...

journal_title：Connective tissue research

authors： Kao RT,Hall J,Stern R

更新日期：1986-01-01 00:00:00

abstract：:STR/ort mice develop a naturally occurring osteoarthritis (OA) of the knee joints. However, the evaluation of early OA changes has been difficult due to variability caused by gender, individual differences, and differences between the right and left lower limbs. The objective of this study was to analyze the variabili...

journal_title：Connective tissue research

authors： Naruse K,Urabe K,Jiang SX,Uchida K,Kozai Y,Minehara H,Mikuni-Takagaki Y,Kashima I,Itoman M

更新日期：2009-01-01 00:00:00