Arthrofibrosis and large joint scarring.

abstract：:Tobacco smoking is considered a major risk factor for the development and progression of periodontal diseases (Haber, J. and Wattles, J. (1994). J. Periodontol., 64, 16-23). The purpose of this study was to determine the effects of nicotine on rat gingival fibroblasts (RGF) cultured in vitro. After ether anesthesia, r...

journal_title：Connective tissue research

authors： Lahmouzi J,Simain-Sato F,Defresne MP,De Pauw MC,Heinen E,Grisar T,Legros JJ,Legrand R

更新日期：2000-01-01 00:00:00

abstract：:We have investigated the changes in some of the biochemical and biophysical properties of human femoral head cartilage on the one hand during ageing and on the other hand in osteoarthritis. Topographical variations were also investigated. The parameters studied were those relevant to cartilage function, viz., proteogl...

journal_title：Connective tissue research

authors： Grushko G,Schneiderman R,Maroudas A

更新日期：1989-01-01 00:00:00

abstract：:The purpose of this study was to investigate overall degradative changes occurring to enamel matrix proteins in small, freeze-dried pieces of rat incisor enamel homogenized and incubated directly for 0-48 hours in a synthetic enamel fluid solution (165 mM total ionic strength with 0.153 mM calcium chloride) versus oth...

journal_title：Connective tissue research

authors： Smith CE,Chen WY

更新日期：1998-01-01 00:00:00

abstract：:Several proteins may play a role in bone formation. The C-propeptide of type II collagen is intimately associated with endochondral bone formation in bovine growth plate. We have used an antibody against this peptide to determine its immunofluorescent distribution in early stages of embryonic chick limb development wi...

journal_title：Connective tissue research

authors： Kujawa MJ,Weitzhandler M,Poole AR,Rosenberg L,Caplan AI

更新日期：1989-01-01 00:00:00

abstract：AIM OF THE STUDY:Tendons are exposed to mechanical stress constantly during movements and thus they are frequently subjected to injuries. Rotator cuff tears are common musculoskeletal disorders, mainly involving the supraspinatus tendon. The characterization of the tenocytes derived from this tendon and the comparison ...

journal_title：Connective tissue research

authors： Viganò M,Lugano G,Orfei CP,Menon A,Ragni E,Colombini A,de Luca P,Talò G,Randelli PS,de Girolamo L

更新日期：2020-09-14 00:00:00

abstract：:The use of electron microscopic observations to characterize the state of aggregation of collagen molecules in solution has been examined from the point of view that the observed structures must be compatible with the physical chemical properties of the solution. The common procedure of addition of droplets of a colla...

journal_title：Connective tissue research

authors： Schwartz D,Veis A

更新日期：1978-01-01 00:00:00

abstract：:Depolymerization of Ch-4-S, Ch-6-S, HA and HP was observed by gel filtration after treatment with 2-10 N NaOH or Ba(OH)2 in the presence of NaBH4 at 80-83 degrees for 1-5 hr. Depolymerized products were isolated after these treatments. 4-Deoxy-alpha-L-threo-4-enohexopyranosyluronic acid residue as the nonreducing end ...

journal_title：Connective tissue research

authors： Hirano S,Ishigami M,Koga Y

更新日期：1975-01-01 00:00:00

abstract：:Eruption requires synchrony of the tooth with the surrounding tissues, particularly the bone. One important step during eruption is remodelling of the alveolar bone at the base of the tooth and along the roots. Expression of BMP6 was reported to be increased in the basal half of the dental follicle prior to eruption a...

journal_title：Connective tissue research

authors： Oralová V,Chlastáková I,Radlanski RJ,Matalová E

更新日期：2014-10-01 00:00:00

abstract：:Changes in the structure and organization of collagen fibrils were recently described in the skin of aspartylglycosaminuria patients. The skin of the patients contained a normal amount and distribution of glycosaminoglycans, but the dermatan sulfate of aspartylglycosaminuria skin was more sensitive to chondroitinase A...

journal_title：Connective tissue research

authors： Näntö-Salonen K,Larjava H,Säämanen AM,Heino J,Penttinen R,Pelliniemi LJ,Tammi M

更新日期：1987-01-01 00:00:00

abstract：:The oxidation of an elastin substrate by highly purified bovine aortic lysyl oxidase (LO) is markedly influenced by amphiphilic molecules known to bind to elastin. Negatively charged elastin ligands, including fatty acids, bile salts or sodium dodecyl sulfate can completely inhibit the oxidation of lysine in elastin, ...

journal_title：Connective tissue research

authors： Kagan HM,Simpson DE,Tseng L

更新日期：1981-01-01 00:00:00

abstract：:The molecular substructure of human articular cartilage has been difficult to study because of its complex composition and high degree of hydration. Using newly available small-angle X-ray diffraction (SAX) instrumentation that allows very short exposure times (0.1 to 10 sec), we have obtained spatially resolved infor...

journal_title：Connective tissue research

authors： Mollenhauer J,Aurich M,Muehleman C,Khelashvilli G,Irving TC

更新日期：2003-01-01 00:00:00

abstract：:The meniscal cartilages in the knee function to improve congruity of the medial and lateral femoro-tibial joints and play critical roles in load distribution and joint stability. Meniscal tears of various configurations are one of the most common conditions of the knee and are associated with an increased risk of deve...

journal_title：Connective tissue research

authors： Melrose J,Fuller ES,Little CB

更新日期：2017-01-01 00:00:00

abstract：:Fitting children and infants who have osteogenesis imperfecta (OI) with braces has posed substantial problems of implementation and patient management For the past twelve years bracing has been an important component of a patient research and management program conducted at the National Institutes of Health. By using ...

journal_title：Connective tissue research

authors： Weintrob JC

更新日期：1995-01-01 00:00:00

abstract：:Ligaments have limited regenerative potential and as a consequence, repair is protracted and results in a mechanically inferior tissue more scar-like than native ligament. We previously reported that a single injection of interleukin-1 receptor antagonist (IL-1Ra) delivered at the time of injury, decreased the number ...

journal_title：Connective tissue research

authors： Chamberlain CS,Leiferman EM,Frisch KE,Duenwald-Kuehl SE,Brickson SL,Murphy WL,Baer GS,Vanderby R

更新日期：2014-06-01 00:00:00

abstract：:Although intervertebral disc (IVD) degeneration is one of most common causes of morbidity, its etiology remains unclear. In healthy discs, the rates of synthesis and breakdown of the extracelluar matrix (ECM) are in equilibrium because of intricate regulation by growth factors and catabolic cytokines. Important among ...

journal_title：Connective tissue research

authors： Cho H,Lee S,Park SH,Huang J,Hasty KA,Kim SJ

更新日期：2013-01-01 00:00:00

abstract：:Bone morphogenetic proteins (BMPs) are known to promote periodontal tissue regeneration, while noggin inhibits the biological activities of BMP-2, -4, and -7. To investigate the effect of BMPs and noggin gene transfer on cementogenesis, we used cloned murine cementoblasts (OCCM). Cells were transduced using adenovirus...

journal_title：Connective tissue research

authors： Jin QM,Zhao M,Economides AN,Somerman MJ,Giannobile WV

更新日期：2004-01-01 00:00:00

abstract：:Many organisms from a wide variety of taxa produce amorphous calcium carbonate (ACC), despite the fact that it is inherently unstable and relatively soluble in its pure state. These properties also make it difficult to detect and characterize ACC. Raman spectroscopy is a particularly useful method for investigating AC...

journal_title：Connective tissue research

authors： Weiner S,Levi-Kalisman Y,Raz S,Addadi L

更新日期：2003-01-01 00:00:00

abstract：:The pharmacokinetics of desmosine following a 5 mg intravenous dose was determined in five sheep. The biological half-life (t 1/2 beta) of desmosine varied between 81-489 min. Urinary recovery of unchanged desmosine indicated that the compound is not extensively metabolized and that the primary route of elimination is...

journal_title：Connective tissue research

authors： Verma PS,Hoyt RF Jr,Jackson AJ,Phillips YY

更新日期：1984-01-01 00:00:00

abstract：:This study aims to elucidate the feasible geometry of the scaffolds in bone and periodontal tissue engineering. Several biomaterials with different geometries are compared in terms of their patterns of ectopic BMP-induced chondrogenesis and osteogenesis. The materials include a honeycomb-shaped hydroxyapatite (HCHAP) ...

journal_title：Connective tissue research

authors： Kuboki Y,Jin Q,Kikuchi M,Mamood J,Takita H

更新日期：2002-01-01 00:00:00

abstract：:In the early mineralized enamel crystals, ribbon-like crystals appear near the ameloblasts. Some ribbon-like crystals showed helical or spiral structure within restricted environment during the preparation of embryonic bovine specimens for electron microscope. These specimens did not suffer from the cutting damages no...

journal_title：Connective tissue research

authors： Suzuki K,Sakae T,Kozawa Y

更新日期：1998-01-01 00:00:00

abstract：:Tubulointerstitial nephritis antigen (TIN-ag) is a recently described basement membrane component reactive with autoantibodies in some forms of autoimmune mediated tubulointerstitial nephritis. Immunofluorescence studies using polyclonal and monoclonal antibodies have indicated a restrictive tissue distribution for TI...

journal_title：Connective tissue research

authors： Nelson TR,Butkowski RJ,Michael AF,Charonis AS

更新日期：1997-01-01 00:00:00

abstract：:Purpose: Transplantation of autologous and/or allogeneic blood vessels is the most convenient treatment for vascular diseases. With regard to extensive need for blood vessels, developments in vascular tissue engineering are contributing greatly. In this study, our aim is to create intact small-diameter tubular vascula...

journal_title：Connective tissue research

authors： Çelebi-Saltik B,Öteyaka MÖ,Gökçinar-Yagci B

更新日期：2021-03-01 00:00:00

abstract：:The paper reviews the changes in ameloblast ultrastructure, concomitant with the changes in its functions across the major stages of amelogenesis. It describes the mechanisms associated with the major events in biosynthesis and degradation of the major enamel proteins (amelogenins and tuftelin/enamelins) and with the ...

journal_title：Connective tissue research

authors： Deutsch D,Catalano-Sherman J,Dafni L,David S,Palmon A

更新日期：1995-01-01 00:00:00

abstract：:Growth and differentiation factor-5 (GDF-5) is known to induce tendon tissue and stimulate tendon healing. The hypothesis was that adenoviral GDF-5 transfer leads to transitory transgene expression and improves Achilles tendon healing. In vitro experiments were first performed with rat tenocytes. Transgene expression ...

journal_title：Connective tissue research

authors： Rickert M,Wang H,Wieloch P,Lorenz H,Steck E,Sabo D,Richter W

更新日期：2005-01-01 00:00:00

abstract：:Currently, the mechanism governing the regeneration of the soft tissue-to-bone interface, such as the transition between the anterior cruciate ligament (ACL) and bone, is not known. Focusing on the ACL-to-bone insertion, this study tests the novel hypothesis that interactions between cells from the ligament (fibroblas...

journal_title：Connective tissue research

authors： Wang IE,Bogdanowicz DR,Mitroo S,Shan J,Kala S,Lu HH

更新日期：2016-11-01 00:00:00

abstract：:To explore crucial early molecular events involved in contact healing of the intrasynovial flexor tendon, integrin expression was evaluated at the transcriptional and post-transcriptional levels during the first two weeks following injury, repair and controlled passive motion in a canine model. Specifically, immunohis...

journal_title：Connective tissue research

authors： Harwood FL,Monosov AZ,Goomer RS,Gelberman RH,Winters SC,Silva MJ,Amiel D

更新日期：1998-01-01 00:00:00

abstract：:Transforming growth factor beta (TGF-beta) is a ubiquitous regulator of cellular growth and differentiation. The present study investigated the effects of TGF-beta on chick growth plate chondrocyte proliferation, matrix synthesis, and alkaline phosphatase activity in short term cultures. TGF-beta markedly stimulated D...

journal_title：Connective tissue research

authors： Rosier RN,O'Keefe RJ,Crabb ID,Puzas JE

更新日期：1989-01-01 00:00:00

abstract：:During cloning of the rat incisor phosphophoryn gene, several clones were identified with a PP antibody. One of the clones (2PP) was shown to encode a PP denoted as dentin matrix protein 2, DMP2. We have now sequenced another clone, which appears to be bifunctional, or at minimum, has two distinct domains. The 5' regi...

journal_title：Connective tissue research

authors： George A,Srinivasan RThotakura SR,Liu K,Veis A

更新日期：1999-01-01 00:00:00

abstract：:The purpose of this study was to examine the hypoxic and inflammatory conditions after immobilization in the joint capsule of rat knees. The unilateral knee joints of adult male rats were immobilized with an internal fixator (Im group) for 1 day, 3 days, and 1, 2, 4, 8, and 16 weeks. Sham-operated animals had holes dr...

journal_title：Connective tissue research

authors： Yabe Y,Hagiwara Y,Suda H,Ando A,Onoda Y,Tsuchiya M,Hatori K,Itoi E

更新日期：2013-01-01 00:00:00

abstract：:Ameloblastic tissue samples from unerupted bone molars were used to prepare subcellular enamel protein kinase preparations, nuclear + plasma membrane, cytosolic and microsomal, and used in in vitro phosphorylation of purified 20 kDa bovine amelogenin in the presence of 32P-ATP. Both cytosolic and microsomal preparatio...

journal_title：Connective tissue research

authors： Salih E,Huang JC,Strawich E,Gouverneur M,Glimcher MJ

更新日期：1998-01-01 00:00:00