Orthotic management for children with osteogenesis imperfecta.

abstract：:Activation of protein kinase C (PKC) can upregulate tooth eruption molecules such as osteoprotegerin (OPG) and vascular endothelial growth factor (VEGF). In this study, we examined the in vivo gene expression of classic isoforms of PKC in the dental follicle of postnatal rats. The expression level of PKC-alpha was sig...

journal_title：Connective tissue research

authors： Yao S,Wise G

更新日期：2004-01-01 00:00:00

abstract：:Purpose: The osteocyte is considered the major mechanosensor in bone, capable of detecting forces at a cellular level to coordinate bone formation and resorption. The pathology of age-related bone loss, a hallmark of osteoporosis, is attributed in part to impaired osteocyte mechanosensing. However, real-time evidence ...

journal_title：Connective tissue research

authors： Morrell AE,Robinson ST,Silva MJ,Guo XE

更新日期：2020-05-01 00:00:00

abstract：:Muscle-derived cells can differentiate into chondrogenic cells. In our present study, we investigated the pattern of expression of Sox9, a transcription factor known to play a key role in chondrogenesis, in a rat myoblastic cell line, L6. In addition, we evaluated expression of type II collagen and myogenic regulatory...

journal_title：Connective tissue research

authors： Matsushita T,Matsui N,Fujioka H,Kubo S,Kuroda R,Kurosaka M,Yoshiya S

更新日期：2004-01-01 00:00:00

abstract：:Cell cultures propagated from fetal bovine ligamentum nuchae were found to accumulate an extensive extracellular matrix containing collagen and elastic fibers when maintained for periods up to 8 weeks. The synthesis by these cells of two glycoproteins, designated MFP I and MFP II, which are immunologically related to ...

journal_title：Connective tissue research

authors： Sear CH,Jones CJ,Knight KR,Grant ME

更新日期：1981-01-01 00:00:00

abstract：:The connective tissue protein elastin is largely responsible for maintaining the elasticity of major blood vessels and lung tissue. Comparatively few studies have been made of the immunologic properties of elastin because of its high degree of insolubility and because of its apparent limited capacity to elicit precipi...

journal_title：Connective tissue research

authors： Kucich U,Christner P,Rosenbloom J,Weinbaum G

更新日期：1981-01-01 00:00:00

abstract：:Purpose/Aim: Cementogenesis is a critical step in periodontal tissue regeneration given the essential role of cementum in anchoring teeth to the alveolar bone. This study is designed to achieve integrated cementum formation on the root surfaces of human teeth using growth factor-releasing scaffolds with periodontal li...

journal_title：Connective tissue research

authors： Cho H,Tarafder S,Fogge M,Kao K,Lee CH

更新日期：2016-11-01 00:00:00

abstract：:Elastic ear cartilage and aortae from nine-day-old hamsters were incubated in Krebs-Ringer medium containing ascorbate, beta-aminopropionitrile and either [14C]proline or [3H]valine. The [14C]proline-labeled proteins were separated by chromatography on Agarose A-5 m in sodium dodecyl sulfate and their [14C]-hydroxypro...

journal_title：Connective tissue research

authors： Heeger P,Rosenbloom J

更新日期：1980-01-01 00:00:00

abstract：:To investigate the source of bone brittleness in the disease osteogenesis imperfecta (OI), biomechanical properties have been measured in the femurs from a homozygous (oim/oim) mutant mouse model of OI, its heterozygous littermates, and wild-type animals. The novel technique of ultrasound critical-angle reflectometry ...

journal_title：Connective tissue research

authors： Mehta SS,Antich PP,Landis WJ

更新日期：1999-01-01 00:00:00

abstract：:To explore crucial early molecular events involved in contact healing of the intrasynovial flexor tendon, integrin expression was evaluated at the transcriptional and post-transcriptional levels during the first two weeks following injury, repair and controlled passive motion in a canine model. Specifically, immunohis...

journal_title：Connective tissue research

authors： Harwood FL,Monosov AZ,Goomer RS,Gelberman RH,Winters SC,Silva MJ,Amiel D

更新日期：1998-01-01 00:00:00

abstract：:The protein components of biomineralized structures (matrix proteins) are believed to modulate crystal nucleation and growth, and thereby influence the shape and strength of the final structure. The chicken eggshell contains a complex array of distinct matrix proteins. One of these was found to have similar molecular ...

journal_title：Connective tissue research

authors： Hincke MT

更新日期：1995-01-01 00:00:00

abstract：:A homogeneous preparation of glycoprotein (apparent molecular weight 34,000) has been isolated from bovine ligamentum nuchae by treatment of the tissue with 5 M guanidine HCl and 2-mercaptoethanol. The preparation exhibits amine oxidase activity which is only marginally inhibited by beta-aminopropionitrile. ...

journal_title：Connective tissue research

authors： Serafini-Fracassini A,Ventrella G,Griffiths R,Hinnie J

更新日期：1981-01-01 00:00:00

abstract：: Purpose/Aim of the study mice are the most often used pre-clinical lab models for studying the pathologies of bone mineralization. However, recent evidence suggests that two of the most often used mice strains (C57BL/6J and CD-1) might show differences in the bone minerali...

journal_title：Connective tissue research

authors： Fayolle C,Labrune M,Berteau JP

更新日期：2020-09-01 00:00:00

abstract：:Hyaluronate lyase from streptococci group A was purified by chromatography on DEAE-Sephadex A-50 and on Biogel P-150, thereby enriching it about 1,000-fold and separating it into two enzyme fractions with the same amino acid composition. The photooxidation of hyaluronate lyase in the presence of methylene blue results...

journal_title：Connective tissue research

authors： Greiling H,Stuhlsatz HW,Eberhard T,Eberhard A

更新日期：1975-01-01 00:00:00

abstract：:Positive effects on the tensile characteristics of swine digital extensors were found following twelve months of exercise training. Compared to sedentary controls, the tendons from the exercised animals became stronger as a material and exhibited hypertrophy. These biomechanical results were supported by biochemical a...

journal_title：Connective tissue research

authors： Woo SL,Ritter MA,Amiel D,Sanders TM,Gomez MA,Kuei SC,Garfin SR,Akeson WH

更新日期：1980-01-01 00:00:00

abstract：:The molecular substructure of human articular cartilage has been difficult to study because of its complex composition and high degree of hydration. Using newly available small-angle X-ray diffraction (SAX) instrumentation that allows very short exposure times (0.1 to 10 sec), we have obtained spatially resolved infor...

journal_title：Connective tissue research

authors： Mollenhauer J,Aurich M,Muehleman C,Khelashvilli G,Irving TC

更新日期：2003-01-01 00:00:00

abstract：:Changes in the structure and organization of collagen fibrils were recently described in the skin of aspartylglycosaminuria patients. The skin of the patients contained a normal amount and distribution of glycosaminoglycans, but the dermatan sulfate of aspartylglycosaminuria skin was more sensitive to chondroitinase A...

journal_title：Connective tissue research

authors： Näntö-Salonen K,Larjava H,Säämanen AM,Heino J,Penttinen R,Pelliniemi LJ,Tammi M

更新日期：1987-01-01 00:00:00

abstract：:We have previously shown in a transgenic mouse line, in which 5.2 kb of the elastin promoter was linked to the reporter enzyme chloramphenicol acetyltransferase (CAT), that the highest levels of expression were found in embryonic lungs and aorta, while lower levels were detected in other elastin-containing tissues. Fu...

journal_title：Connective tissue research

authors： Lakkakorpi J,Li K,Decker S,Korkeela E,Piddington R,Abrams W,Bashir M,Uitto J,Rosenbloom J

更新日期：1999-01-01 00:00:00

abstract：:Oriented fibers, arising from the self assembly of collagen, may be produced from in vitro fibrillogenesis of soluble collagen with gradients of fibrillogenic potential. These gradients may be introduced by either concentration gradients of pronase-treated collagen or of arginine which, in turn, create concentration g...

journal_title：Connective tissue research

authors： Ghosh S,Comper WD

更新日期：1988-01-01 00:00:00

abstract：:The interaction of elastin and microfibrils in elastogenesis in vitro was investigated with electron microscopy and immunohistochemistry. Fetal human pulmonary fibroblasts were cultured with or without beta-aminopropionitrile (BAPN). One week after seeding, the extracellular microfibrils were loosely arranged without ...

journal_title：Connective tissue research

authors： Fukuda Y,Nakazawa N,Yamanaka N

更新日期：1993-01-01 00:00:00

abstract：:Purpose: In our previous study, we demonstrated that hyaluronan induces odontoblastic differentiation of dental pulp stem cells via interactions with CD44. However, it remains unclear whether CD44 expression by dental pulp stem cells is required for odontoblastic differentiation. Methods: We searched for a compound ot...

journal_title：Connective tissue research

authors： Kajiura K,Umemura N,Ohkoshi E,Ohta T,Kondoh N,Kawano S

更新日期：2021-01-12 00:00:00

abstract：:Two populations of primary osteoblasts and the cloned murine osteoblast cell line MC3T3 were activated with osteotropic agents and the conditioned media tested for the presence of macrophage colony stimulating factor (M-CSF). Differences in ability of the three populations to secrete the cytokine as well as in the eff...

journal_title：Connective tissue research

authors： Horowitz MC,Einhorn TA,Philbrick W,Jilka RL

更新日期：1989-01-01 00:00:00

abstract：AIM OF THE STUDY:To further elucidate the pathogenesis of systemic sclerosis (SSc) an experimental avian model was used. The University of California at Davis line 200 (UCD-200) chickens spontaneously develop a SSc-like disease that has most features of human SSc with vascular effects, inflammation, autoimmunity, and f...

journal_title：Connective tissue research

authors： Kerje S,Hellman U,Do L,Larsson G,Kämpe O,Engström-Laurent A,Lindqvist U

更新日期：2016-09-01 00:00:00

abstract：:The expression of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) by human vascular smooth muscle cells (SMC) was monitored as a function of the phenotypic modulation in vitro. Cell phenotype was manipulated by varying serum concentration and cell density. Synthetic phenotype was characterized by a minim...

journal_title：Connective tissue research

authors： Kato S,Yasukawa H,Fujii T,Yamaguchi M,Miyagi N,Okamoto K,Wada Y,Miyamoto T,Morimatsu M,Fox JC

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:Treatment of meniscal injury is important for osteoarthritis (OA) prevention. Meniscus cells are divided between inner and outer cells, which have different characteristics and vascularity. We evaluated the effects of hyaluronic acid (HA) on the proliferation and migration of human inner and outer meniscus cell...

journal_title：Connective tissue research

authors： Murakami T,Otsuki S,Okamoto Y,Nakagawa K,Wakama H,Okuno N,Neo M

更新日期：2019-03-01 00:00:00

abstract：:Heparin treated and aldehyde crosslinked rat aorta segments were implanted in infrarenal aorta of homologous rats. One year following aortic replacement, the subendothelial scar and the prosthetic remnants were excised. The scar and the host intima-media were incubated with 3H-valine for 4 h and extracted with 5 M gua...

journal_title：Connective tissue research

authors： Moczar M,Bessou JP,Loisance D

更新日期：1983-01-01 00:00:00

abstract：:Size measurements of dispersed rat bone crystals show that with age a greater proportion exceeds 400 A in length. The surface fractures of more heavily mineralized bones tend to be smooth and stepped, whereas those of less mineralized bones are fibrous. These observations combined with information reported elsewhere o...

journal_title：Connective tissue research

authors： Weiner S,Traub W

更新日期：1989-01-01 00:00:00

abstract：:Calbindin-D9k and calbindin-D-28k genes are useful systems to investigate the tissue- and stage-specificity as well as the hormonal control of gene expression. Since they regulate cellular calcium mobilization, their study may be of interest in mineralized tissues. However, thus far, immunocytochemical labelling has b...

journal_title：Connective tissue research

authors： Hotton D,Davideau JL,Bernaudin JF,Berdal A

更新日期：1995-01-01 00:00:00

abstract：:Several proteins may play a role in bone formation. The C-propeptide of type II collagen is intimately associated with endochondral bone formation in bovine growth plate. We have used an antibody against this peptide to determine its immunofluorescent distribution in early stages of embryonic chick limb development wi...

journal_title：Connective tissue research

authors： Kujawa MJ,Weitzhandler M,Poole AR,Rosenberg L,Caplan AI

更新日期：1989-01-01 00:00:00

abstract：:EMDOGAIN is derived from porcine developing enamel matrix and has been shown to facilitate regeneration of the periodontium, although its mechanism of action is unknown. The aim of the present study was to identify enamel matrix proteins and proteolytic enzymes present in EMDOGAIN and compare them with those extracted...

journal_title：Connective tissue research

authors： Maycock J,Wood SR,Brookes SJ,Shore RC,Robinson C,Kirkham J

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:Excessive apoptosis plays an important role in the progression of intervertebral disc degeneration. However, the effect of autophagy, another type of programmed cell death, on the pathogenesis of disc degeneration is still unclear. Macroautophagy and chaperone-mediated autophagy (CMA) change and intervertebra...

journal_title：Connective tissue research

authors： Ye W,Xu K,Huang D,Liang A,Peng Y,Zhu W,Li C

更新日期：2011-01-01 00:00:00