Abstract:
:Posttransplant lymphoproliferative disorder (PTLD) is a common and life-threatening complication of immunosuppression used to prevent rejection of solid organ and bone marrow transplants. There is no standardized treatment algorithm, but numerous management strategies are available. We describe a patient who developed a solitary lymphoproliferative lesion in the porta hepatis 9 months after orthotopic liver transplant. Following reduction in immunosuppression with no response, she was treated with involved field radiotherapy utilizing CT-based treatment planning. A partial radiographic response was obtained, and she has not developed disease in the engrafted liver or systemically. Based on the present case report, involved field radiotherapy seems to be a reasonable treatment option for patients with localized PTLD. Int. J. Cancer (Radiat. Oncol. Invest.) 90:104-109, 2000.
journal_name
Int J Cancerjournal_title
International journal of cancerauthors
Koffman BH,Kennedy AS,Heyman M,Colonna J,Howell Cdoi
10.1002/(sici)1097-0215(20000420)90:2<104::aid-ijckeywords:
subject
Has Abstractpub_date
2000-04-20 00:00:00pages
104-9issue
2eissn
0020-7136issn
1097-0215pii
10.1002/(SICI)1097-0215(20000420)90:2<104::AID-IJCjournal_volume
90pub_type
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