Abstract:
:In this study, the applicability of a symptom-based questionnaire on hand dermatitis was assessed in a population of rubber workers. The questionnaire was previously validated in a study among nurses. 224 subjects employed in 9 different companies completed a questionnaire on skin complaints. Subsequently, 202 workers attended the physical examination of the skin by a dermatologist. The ascertainment of skin complaints according to the questionnaire was compared to the medical evaluation. The 2 different diagnostic tools used for assessing dermatitis resulted in dissimilar estimates of the prevalence of active hand dermatitis, ranging from 6.9% to 38.1% of all workers. Using the medical evaluation as 'gold standard' we observed a moderate sensitivity and specificity (respectively 71.4%; 95% CI: 47.7-95.1 and 76.1%; 95% CI: 70.0-82.2), a low positive predictive value (18.2%; 95% CI: 8.0-28.4) and a high negative predictive value (97.3%; 95% CI: 94.7-99.9) for the classification based on the self-administered questionnaire. When evaluated against 'first symptoms of dermatitis' the sensitivity decreased, while the specificity remained almost the same. The deviant findings between the present and the original validation study of the same questionnaire among nurses hamper its applicability in populations with different occupations. Therefore, if questionnaires are to be used, validity studies have to be carried out to evaluate differences in perception of skin diseases between different (occupational) populations.
journal_name
Contact Dermatitisjournal_title
Contact dermatitisauthors
Vermeulen R,Kromhout H,Bruynzeel DP,de Boer EMdoi
10.1034/j.1600-0536.2000.042004202.xkeywords:
subject
Has Abstractpub_date
2000-04-01 00:00:00pages
202-6issue
4eissn
0105-1873issn
1600-0536journal_volume
42pub_type
杂志文章abstract::Some methacrylates are known to be strong contact sensitizers. To determine the effect of side-chain length on sensitizing potential, we examined 11 derivatives with linear side chains from C1 to C18 in an experimental sensitization test in guinea pigs. The results showed an increase in the sensitizing potential with ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1999.tb05971.x
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Contact allergy to dental materials is poorly understood; clinical manifestations are heterogeneous. OBJECTIVE:To analyse positive patch test reactions to metals (as their alloys or salts) used in dentistry together with clinical symptoms and possible relevance to dental fillings. METHODS:We retrospectivel...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2009.01524.x
更新日期:2009-06-01 00:00:00
abstract::Interleukin-12 (IL-12) has previously been suggested as playing a major rôle in the activation of cytotoxic lymphocytes. Recent reports indicate that cytotoxic CD8+ cells are critically involved in the elicitation phase of contact hypersensitivity reactions. In this study, the in situ expression of IL-12 was investiga...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1034/j.1600-0536.2000.042001018.x
更新日期:2000-01-01 00:00:00
abstract::Japanese lacquer is made from the sap of the Japanese lacquer tree (Toxicodendron vernicifluum), a member of the Anacardiacae plant family. Objects painted with this material are described collectively as lacquerware. Both fresh lacquer and lacquerware may evoke allergic contact reactions ascribable to the urushiols c...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1992.tb03254.x
更新日期:1992-10-01 00:00:00
abstract::Many factors can influence the elicitation of hypersensitivity reactions in guinea pigs and humans. The effect which the vehicle might have on the test response in guinea pigs sensitized with various acrylic compounds, using the "guinea pig maximization test", has been investigated. A marked decrease in the number of ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1984.tb01008.x
更新日期:1984-11-01 00:00:00
abstract:BACKGROUND:Hand eczema is common in the nursing profession, and has been reported widely in various parts of the world. OBJECTIVES:The aim of this study was to determine the prevalence and severity of hand eczema among nurses working in a regional hospital in Hong Kong, as well as its psychosocial impact and any possi...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2011.01961.x
更新日期:2011-12-01 00:00:00
abstract::The literature is reviewed for contact dermatitis associated with transdermal therapeutic systems. Clonidine, nitroglycerin, scopolamine, estradiol and testosterone are utilized in such applications, and fentanyl is under investigation. Most cutaneous reactions are limited to localized dermatitis; however, generalized...
journal_title:Contact dermatitis
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0536.1989.tb03087.x
更新日期:1989-01-01 00:00:00
abstract::Deodorized kerosene in a concentration of 50 g/100 g in pet. did not cause cutaneous inflammation in 10 control guinea pigs. The proportion of 19 guinea pigs exhibiting inflammation following exposure to deodorized kerosene in the guinea pig maximization test increased, but the increase was not significant. The respon...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1983.tb04459.x
更新日期:1983-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The aim of this cross-sectional study was to collect data on the prevalence of hand eczema and relevant risk factors in geriatric nurses in Germany. METHODS:1375 geriatric nurses from 86 nursing homes were investigated by 41 occupational physicians. RESULTS:Hand eczema was diagnosed in 243 n...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2008.01496.x
更新日期:2009-03-01 00:00:00
abstract::In two cases, occupational contact dermatitis was found to be due to chicory (Cichorium) used as a salad plant. In one of the two cases, contact sensitivity to letuce (Lactuca) was also observed. The sesquiterpene lactones of the plant may be the allergens. ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1975.tb05444.x
更新日期:1975-10-01 00:00:00
abstract::The Persian cloth shoe (Maleki) which has been in use for more than 800 years has a strong cloth sole and a woven cotton upper. In the last 20 years, used car tires have become readily available in Iran and the soles of some shoes are now made from these. A man with the typical picture of rubber dermatitis on the sole...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1977.tb03605.x
更新日期:1977-04-01 00:00:00
abstract::To critically review currently available methods, or methods under development (in vivo, in vitro, in silico, etc.) used in the evaluation of skin sensitization potential and their applicability in the derivation of quantitative 'safety thresholds'. ...
journal_title:Contact dermatitis
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0536.2011.02004_2.x
更新日期:2012-04-01 00:00:00
abstract::Metallic aluminium and methylene blue applied to human skin interact and give a strong resistant coloration, obtained neither with methylene blue itself nor with other dyes. The reaction proves that aluminium is not an inert material and that the aluminium in Finn chambers can be expected to interact with other patch ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1985.tb01031.x
更新日期:1985-01-01 00:00:00
abstract::In a study of sickness absence due to occupational dermatoses among 360 construction workers in a prefabrication construction factory in 1984, we found 3 workers with allergic contact dermatitis from chromate in cement who required medical leave. There were 5 sickness absence spells due to occupational dermatoses and ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1986.tb01257.x
更新日期:1986-07-01 00:00:00
abstract::Thiourea compounds are mainly used as accelerators in the rubber industry, but also in other industries, e.g., as antioxidants in the graphics industry. Thiourea compounds may provoke allergic contact dermatitis, although the number of reported cases is relatively low. During 1985-1991, we had 5 patients with allergic...
journal_title:Contact dermatitis
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0536.1994.tb01996.x
更新日期:1994-10-01 00:00:00
abstract:BACKGROUND:Contact allergy prevalence rates change over time as a result of variations in allergen exposure. Data from patch test clinics are often used as markers for allergy trends. OBJECTIVES:The aim of the present retrospective study was to describe trends in rates of sensitization to allergens in the Swedish base...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/cod.12346
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Protein contact dermatitis is a frequent disorder among hand eczema patients who have occupational food contact. Knowledge about the consequences of having protein contact dermatitis is lacking. OBJECTIVES:To investigate the consequences of having occupational skin disease on the hands resulting from food h...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.2012.02101.x
更新日期:2012-12-01 00:00:00
abstract::Numerous studies have focused attention on the influence of various biological and environmental factors on contact hypersensitivity. In order to evaluate the persistence and/or modification of allergic contact sensitivity to a number of common contact sensitizers, the same standardized patch tests were repeated on 17...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1996.tb02222.x
更新日期:1996-05-01 00:00:00
abstract::A 50-year-old woman developed anaphylaxis 8 h after application of a paraformaldehyde-containing root canal disinfectant. Radioallergosorbent test showed that she had a high level of formaldehyde-specific IgE in her serum. Prick tests to formaldehyde and paraformaldehyde showed immediate-type responses to both. We rev...
journal_title:Contact dermatitis
pub_type: 杂志文章,评审
doi:10.1034/j.1600-0536.2002.470405.x
更新日期:2002-10-01 00:00:00
abstract::To test the screening value of the sesquiterpene lactone (SL) mix in Europe today and describe epidemiological and clinical features of Compositae-sensitive patients, the SL mix 0.1% pet. was included in the standard patch test series in 11 European clinics. 10,695 patients were tested, and 106 (1%) had positive react...
journal_title:Contact dermatitis
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/j.1600-0536.1999.tb05994.x
更新日期:1999-02-01 00:00:00
abstract::The present study aimed at evaluating the effects of daily repeated exposures to low cobalt or chromate concentrations on the hands of patients with hand eczema and cobalt or chromate allergy. For 2 weeks, the patients immersed a finger for 10 min daily into the appropriate metal salt solution in water. During the 1st...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1034/j.1600-0536.2000.043004212.x
更新日期:2000-10-01 00:00:00
abstract::3 minor resin acids and 7 commercial modified-colophony products of different origins were studied by experimental sensitization by means of a modified FCA method. All 3 resin acids were almost negative. The commercial products gave different results. While the maleic-modified product of Greek origin showed a strong s...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1990.tb03229.x
更新日期:1990-08-01 00:00:00
abstract::Data on 134 consecutive nickel-sensitive subjects attending our contact dermatitis clinic were analysed. The female to male ratio was 8 to 1, with a mean age at presentation of 35 years for women and 53 years for men. Hand dermatitis occurred in 49% of patients and in 70% of men. It was usually preceeded by jewellery ...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1986.tb01198.x
更新日期:1986-03-01 00:00:00
abstract::A chemical operator handling dimethyl acetylenedicarboxylate (DMAD) developed delayed and pain-free burns on one of his feet 2 days after a supposed spillage of DMAD. The injuries were confirmed to be associated with DMAD by chemical analysis of the operator's safety boot and patch tests. DMAD easily penetrates some p...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1984.tb00166.x
更新日期:1984-07-01 00:00:00
abstract::Serum from guinea pigs exposed to a single high dose of UVB and from controls was injected into the spleen of normal animals 5 days prior to sensitization. When 1.0 ml was transferred 4.5 h after irradiation, immunosuppression was obtained. Transfer of 1.5 ml of serum 2.5 h after irradiation failed to induce immunosup...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1987.tb01426.x
更新日期:1987-04-01 00:00:00
abstract::Although cinnamon is known to cause dermatitis in bakers and confectioners, it has only rarely been reported as causing trouble in food or cosmetics. A newly-formulated 'spicy' toothpaste containing cinnamon as a flavouring agent was the cause of oral symptoms in eight patients referred to clinics in Buckinghamshire a...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1975.tb05330.x
更新日期:1975-01-01 00:00:00
abstract::The phenomenon of 'sensitive skin' is a relatively recent complaint in which certain individuals report more intense and frequent adverse sensory effects than the normal population upon use of cosmetic (personal-care) products. Originally defined as a minority complaint, sensitive skin is now claimed by a majority of ...
journal_title:Contact dermatitis
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0536.2009.01697.x
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:In 2011, a multicentre study was conducted in order to determine how hair dye manufacturers instructed consumers to perform a self-test prior to dyeing their hair, in order to identify individuals who are likely to react upon subsequent hair dyeing. A number of concerns were raised concerning the variability...
journal_title:Contact dermatitis
pub_type: 杂志文章,多中心研究
doi:10.1111/cod.12882
更新日期:2018-02-01 00:00:00
abstract::Erythema caused by occlusion of 3 concentrations of surfactant was quantified in vivo using a modified spectrophotometer. Standard chamber irritation test sites were evaluated objectively using the spectrophotometer and subjectively by trained observers. There was a good relationship between the instrumental and visua...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1988.tb02893.x
更新日期:1988-09-01 00:00:00
abstract::Despite the frequency of irritant contact dermatitis, very little is known about the duration of barrier function impairment following cumulative irritant contact dermatitis. We studied post-irritation irritant reactivity by assessing the response to SLS irritation in previously irritated sites. Cumulative irritant co...
journal_title:Contact dermatitis
pub_type: 杂志文章
doi:10.1111/j.1600-0536.1994.tb00725.x
更新日期:1994-01-01 00:00:00