Abstract:
BACKGROUND:Whether Doppler ultrasonography (DU) may be of help in characterizing thyroid nodes is still under debate: both good and unsatisfactory results have been claimed, either in evaluating the presence of malignancy or in identifying hyperfunctional structures. METHODS:In this paper, the scintigraphic and Doppler patterns of 80 thyroid nodes have been compared, in the hypothesis that there may be some correlation between functional status and vascularity of the node; a small group of cyto-histological information were considered too. RESULTS:Perilesional flux seems to be, in general, somewhat more frequent than intranodal or mixed patterns: this is, however, true for all the groups of nodular functional conditions studied (peripheric flux was found in 70.2% of hyperfunctioning, 63.6% of isofunctioning and 59.3% of hypofunctioning nodes; intranodular flow was present in 18.9, 9 and 21.8% of hyper-, iso and hypofunctioning nodes respectively; mixed flow was found in 10.8% hyper, 27.2% iso and 18.7% hypofunctioning nodes). CONCLUSIONS:A prevalence of peripheric flow pattern is almost evenly distributed in all class of differently functioning nodes. Our data support the conclusion that no reliable correlations exist between scintigraphic and DU patterns: DU may not, therefore, be considered a valid substitute for nuclear imaging.
journal_name
Minerva Endocrinoljournal_title
Minerva endocrinologicaauthors
Lupi A,Cerisara D,Orsolon P,De Antoni G,Vianello Dri Akeywords:
subject
Has Abstractpub_date
1999-03-01 00:00:00pages
7-10issue
1eissn
0391-1977issn
1827-1634journal_volume
24pub_type
临床试验,杂志文章abstract:: ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.18.02736-0
更新日期:2019-06-01 00:00:00
abstract::According to the literature, the prevalence of papillary thyroid microcarcinoma (PTMC) is increasing. To date, PMTC account for up to 30% of all differentiated thyroid cancers. Patients with PTMC have an excellent prognosis with a normal life expectancy. Because of the differential definitions of the PTMC, the therape...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2009-03-01 00:00:00
abstract::Many hormones and some neuropeptides and neurotransmitters play a key role in regulating numerous lymphoid cell functions. In particular, somatostatin (ss), substance P (sp) and vasoactive intestinal polypeptide (vip) appear to be involved in numerous regulating mechanisms of cell activities in the immune system under...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2001-09-01 00:00:00
abstract::The treatment of NIDDM patients with secondary failure to sulfonylureas is still a debated problem. In this study we compared in NIDDM patients with secondary failure to glyburide, the effect of adding a single, low-dose bed time either NPH or ultralent insulin injection (0.15-0.2 U/kg) to the previously ineffective s...
journal_title:Minerva endocrinologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-06-01 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate long-term effectiveness and safety of liraglutide in real world. METHODS:A diabetes clinic in Italy systematically collected data of all patients treated with liraglutide. Generalized hierarchical linear regression models for repeated measures were applied to assess tre...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2016-03-01 00:00:00
abstract::Familial non-medullary thyroid cancer (FNMTC) constitutes 3-9% of all thyroid cancers and occur in two or more first-degree relatives in the absence of predisposing environmental factors. Out of all FNMTC cases, only 5% are represented by syndromic forms (Gardner's syndrome, familial adenomatous polyposis, Cowden's sy...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.20.03338-6
更新日期:2020-10-12 00:00:00
abstract::Primary hyperparathyroidism is a not uncommon disease in the elderly. A prevalence of 3% for women and 1% for men is reported in subjects aged 65 years and over. Routine serum calcium determination and parathyroid hormone radioimmuno-assay allow to make an early diagnosis in still asymptomatic subjects. In the elderly...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract::Hyponatremia is common in neurosurgical patients and is associated with significant morbidity and mortality. Despite significant research efforts to date, we still lack a complete understanding of the pathophysiological mechanisms underlying hyponatremia in this patient setting. The purpose of this narrative review is...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2014-03-01 00:00:00
abstract::Thyroid nodule is extremely common. Its prevalence has been estimated to be more than 5% in the adult population. If thyroid nodule is a rare condition, 0.004% a year, identifying those nodules, which are likely to be malignant, is very important for physicians. The evaluation of thyroid is carried out using the fine ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:1993-09-01 00:00:00
abstract::New-onset diabetes after transplantation (NODAT) or posttransplant diabetes mellitus is a frequent metabolic complication of organ transplantation. Diabetes incidence rates among transplant recipients are higher than in the general population. The estimated rates are 9-18% after kidney, 20-33% after liver, 26-40% afte...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2012-09-01 00:00:00
abstract::Adrenal scintigraphy using 131I-6-beta-iodomethyl-19-norcholesterol or 6-methyl-75Se-methyl-19-norcholesterol is a function-dependent imaging method which, in association with high-resolution spatial imaging techniques, plays an essential role in the study of adrenocortical hyperfunction. It can distinguish between bi...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:1995-03-01 00:00:00
abstract:BACKGROUND:Multicellular spheroids represent an interesting experimental model with promising applications in the pre-clinical studies on anticancer drugs. We recently demonstrated that thyroid spheroids recapitulate the features of the original tissues, in either the differentiated and "stem-like" components. Here we ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.17.02610-4
更新日期:2018-03-01 00:00:00
abstract::This review concerns the relation between most frequent thyroid gland diseases and diabetes mellitus in adult patients. Special attention is paid to autoimmune thyroiditis, Graves' disease, thyroid autoimmunity in pregnant diabetic women, and iodine metabolism. We focused on mechanisms leading to coexistence of both e...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2005-12-01 00:00:00
abstract::The desire to reproduce is a base human instinct. However, for many individuals, the chances of being able to have a genetic child are compromised by a number of factors. For some, therapies aimed at treating serious medical illness, such as cancer; result in a deleterious impact on the function of eggs and sperm in t...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:10.23736/S0391-1977.17.02666-9
更新日期:2018-03-01 00:00:00
abstract::Loss of estrogens or androgens causes bone loss by increasing the rate of bone remodeling, and also causes an imbalance between resorption and formation by prolonging the lifespan of osteoclasts and shortening the lifespan of osteoblasts. Conversely, treatment with androgens, as well as estrogens, maintains cancellous...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2005-03-01 00:00:00
abstract::Cushing's syndrome is a serious endocrine condition for which no treatment has been proven fully satisfactory at least for its pituitary dependent form (Cushing's disease). Indeed, despite some advances in pharmacology (cyproheptadine, bromocriptine, lisuride) and in surgical and radiation procedures at pituitary leve...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::The major issue currently being faced in the management of prostate cancer is the inability to distinguish between indolent prostate tumors that will not present clinically from more aggressive and metastatic prostate cancers that will impact on men's lives. Only a small proportion of prostate cancers can be accounted...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2012-06-01 00:00:00
abstract::It is known that young female cancer survivors are at higher risk for decreased fertility and early menopause. Because the risk of these outcomes varies by age, cancer type, treatment regimen and other patient-specific characteristics, there is a need for valid tools for measuring and predicting reproductive function ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2010-12-01 00:00:00
abstract::Acromegaly is a rare disease characterized by high levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1). The excess of GH leads to the development of different manifestations in different organs, from subtle signs in the bones and soft tissues to the development of respiratory and cardiac insufficien...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:10.23736/S0391-1977.18.02930-9
更新日期:2019-06-01 00:00:00
abstract::A number of studies have been carried out over the past year to characterise the physiological functions and possible therapeutic applications of somatostatin (sst). Somatostatin is one of the most widespread peptides in the body and it fulfils a very wide spectrum of actions in the various organs and tissues. The aim...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2001-09-01 00:00:00
abstract::Growth hormone (GH) has been recently approved by the Italian Health Authorities for use in transition patients with childhood onset-growth hormone deficiency (CO-GHD). GH in addition to promote linear growth influences several key metabolic processes. In particular, in the transition period, from late adolescent to e...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2015-03-01 00:00:00
abstract::We treated with PEI 81 patients carriers of autonomous thyroid nodule, 65 toxic and 16 non toxic, all with undetectable serum TSH and suppressed extranodular tissue on scintigraphy. The treatment schedule was: 1-2 sessions per week, 1-8 ml per session, 3-13 sessions in total, In relation to the size and the therapeuti...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract:AIM:The aim of this paper was to determine the prevalence of altered sensorium and their determinants in diabetic ketoacidosis (DKA). METHODS:Retrospective review of medical records for diabetic ketoacidosis admissions over a two year period. RESULTS:A total of 94 admissions for DKA in 89 patients were reviewed. Majo...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract::Subclinical hypothyroidism - i.e., a condition characterized by serum TSH concentrations above the normal reference range in the presence of normal serum T4 levels - affects 4 to 20% of the population living in iodine-sufficient areas. The present work reviews the clinical challenges regarding, on the one hand, the si...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.20.03176-4
更新日期:2020-08-03 00:00:00
abstract::The normal growth and development of the prostate requires the presence and action of androgens, which are also known risk factors in the origins of benign and malignant prostate disease. Paradoxically, the incidence of prostate disease increases with age when serum androgen levels are in decline and emerging evidence...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2006-03-01 00:00:00
abstract::Notwithstanding recent neuroendocrinological and neuroradiological findings, about 40% of carriers of pituitary adenoma still reach clinical observation and, consequently, the surgeon, in the stage of suffering from extrasellar extension to a varying degree, especially when the volumetric growth of the lesion is not a...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract::A 49-year-old man presented with a 6-month history of weight loss, muscular weakness, easy fatigue, impotence, decreased visual acuity, campimetry defects. The results of radiologic and endocrine testing disclosed the presence of pituitary dysfunction due to pituitary stalk section caused by a giant suprasellar aneury...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1989-10-01 00:00:00
abstract::A 49 year-old woman with anaplastic thyroid carcinoma came, for the first time, to our clinic with an enlarged supraclavicular lymph node. Ten years earlier she received a diagnosis of benign nodular goiter and has been followed up with ultrasonography, which never demonstrated any enlargement of her thyroid nodule an...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract::Breast cancer is the second most frequent type of cancer worldwide and the most commonly occurring malignancy in women, and its incidence is increasing in most developed and developing countries. There is growing evidence that lifestyle factors, in particular diet may be associated with higher Breast Cancer risk. Some...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.20.03266-6
更新日期:2020-09-24 00:00:00
abstract::For decades gross-total resection was the preferred treatment option in childhood-onset craniopharyngioma, assuming that radical strategies at the time of initial diagnosis and treatment would result in cure. Recent reports on long-term prognosis, novel treatment approaches, and molecular genetics provide new insights...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,meta分析,评审
doi:10.23736/S0391-1977.17.02615-3
更新日期:2017-12-01 00:00:00