Abstract:
:Breast cancer is the second most frequent type of cancer worldwide and the most commonly occurring malignancy in women, and its incidence is increasing in most developed and developing countries. There is growing evidence that lifestyle factors, in particular diet may be associated with higher Breast Cancer risk. Some evidence exists regarding the benefit of Mediterranean Diet on reduced risk of Breast Cancer in premenopausal and postmenopausal women. The protective effect of the Mediterranean Diet against the risk of Breast Cancer, is primarily due to principal foods of this nutritional pattern. The principal components of the Mediterranean Diet, such as fruits and vegetables, olive oil, fish and red wine have important antioxidants properties due to their high content of substances like polyphenols, flavonoids, carotenoids and fibers, along with a favourable fatty acid profile, that in turn could reduce the risk of Breast Cancer. Considering the severity of breast cancer and the increasing incidence in the world, there is an increasing interest in promoting prevention strategies in order to reduce the incidence. The aim of this paper is to provide a general overview of the current evidence on the relationship between Breast Cancer and Mediterranean Diet, in premenopausal and postmenopausal women, and to emphasize the potential role of Mediterranean Diet as an effective tool in primary prevention. The possible molecular mechanisms underlying this association will be also pointed out.
journal_name
Minerva Endocrinoljournal_title
Minerva endocrinologicaauthors
Laudisio D,Castellucci B,Barrea L,Pugliese G,Savastano S,Colao A,Muscogiuri Gdoi
10.23736/S0391-1977.20.03266-6subject
Has Abstractpub_date
2020-09-24 00:00:00eissn
0391-1977issn
1827-1634pii
S0391-1977.20.03266-6pub_type
杂志文章abstract::Diabetes mellitus (DM) is a group of metabolic disorders of carbohydrate metabolism in which glucose is underutilized, resulting in hyperglycemia. Reproductive impairment in poorly controlled diabetes mellitus type 1 (T1DM) results from a combined effect of insulin deficiency and hyperglycemia that disrupt the functio...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:10.23736/S0391-1977.16.02477-9
更新日期:2017-09-01 00:00:00
abstract::Very-low-calorie ketogenic diet (VLCKD) is a promising lifestyle intervention for the management of overweight and obesity. It is characterized by a restriction of both calories and carbohydrates, while assuring the adequate proteins, fats and micronutrients intake. Significant results in terms of excess body weight l...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.20.03356-8
更新日期:2020-11-19 00:00:00
abstract::Pregnancy in women with a diagnosis of Cushing' syndrome (CS) is an extremely rare event and its diagnosis and treatment are a real medical challenge. During pregnancy, the hypothalamus-pituitary-adrenal axis undergoes major changes leading to a significant increase in plasma cortisol levels throughout gestation. The ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:10.23736/S0391-1977.18.02803-1
更新日期:2018-12-01 00:00:00
abstract::Medullary thyroid carcinoma arises from the C cells, which produce a characteristic hormone, calcitonin. At present, surgery is the main treatment modality. Medullary thyroid carcinoma is usually treated with total thyroidectomy and with removal of nodes in the central portion of the neck and upper mediastinum. Cervic...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:1998-12-01 00:00:00
abstract::Loss of estrogens or androgens causes bone loss by increasing the rate of bone remodeling, and also causes an imbalance between resorption and formation by prolonging the lifespan of osteoclasts and shortening the lifespan of osteoblasts. Conversely, treatment with androgens, as well as estrogens, maintains cancellous...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2005-03-01 00:00:00
abstract:AIM:The aim of this paper was to compare serum high sensitivity C-reactive protein (HsCRP) levels and carotid artery intima-media thickness (CIMT) of patients with impaired glucose tolerance (IGT) or impaired fasting glucose (IFG) with that in control subjects. METHODS:Ninety-six subjects with prediabetes, 48 with IFG...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2013-09-01 00:00:00
abstract::To investigate whether inappropriate LH secretion in Polycystic Ovary Syndrome (PCO) was related to a reduction of inhibitory opioid control on the GnRH-LH system, 23 women affected by PCO (12 obese, BMI: 37.1 +/- 3.9 and 11 non obese, BMI: 21.5 + 2.4) and 19 fertile women (10 obese, BMI: 38.8 + 1.8 and 9 non obese, B...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract::Obesity has become a national epidemic and a disease of global magnitude. The numbers of patients with obesity have grown exponentially in the last 10 years to the degree that the Centers for Disease Control and Prevention reports that one third of the US population is obese. The prevalence of diabetes has grown by mo...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate long-term effectiveness and safety of liraglutide in real world. METHODS:A diabetes clinic in Italy systematically collected data of all patients treated with liraglutide. Generalized hierarchical linear regression models for repeated measures were applied to assess tre...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2016-03-01 00:00:00
abstract::Hyponatremia is common in neurosurgical patients and is associated with significant morbidity and mortality. Despite significant research efforts to date, we still lack a complete understanding of the pathophysiological mechanisms underlying hyponatremia in this patient setting. The purpose of this narrative review is...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2014-03-01 00:00:00
abstract::This review concerns the relation between most frequent thyroid gland diseases and diabetes mellitus in adult patients. Special attention is paid to autoimmune thyroiditis, Graves' disease, thyroid autoimmunity in pregnant diabetic women, and iodine metabolism. We focused on mechanisms leading to coexistence of both e...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2005-12-01 00:00:00
abstract::Acromegaly is a rare disease characterized by high levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1). The excess of GH leads to the development of different manifestations in different organs, from subtle signs in the bones and soft tissues to the development of respiratory and cardiac insufficien...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:10.23736/S0391-1977.18.02930-9
更新日期:2019-06-01 00:00:00
abstract::Subclinical hypothyroidism - i.e., a condition characterized by serum TSH concentrations above the normal reference range in the presence of normal serum T4 levels - affects 4 to 20% of the population living in iodine-sufficient areas. The present work reviews the clinical challenges regarding, on the one hand, the si...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.20.03176-4
更新日期:2020-08-03 00:00:00
abstract::According to the literature, the prevalence of papillary thyroid microcarcinoma (PTMC) is increasing. To date, PMTC account for up to 30% of all differentiated thyroid cancers. Patients with PTMC have an excellent prognosis with a normal life expectancy. Because of the differential definitions of the PTMC, the therape...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2009-03-01 00:00:00
abstract::Multiple endocrine neoplasia type 1 (MEN1; formerly known as Wermer syndrome) is a rare disorder characterized by the combined occurrence of two or more tumors involving parathyroid, pancreatic islets and anterior pituitary glands; some other tumors have also been described. In most cases it is inherited in an autosom...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2013-03-01 00:00:00
abstract:UNLABELLED:Anaplastic thyroid cancer (ATC) is a rare aggressive tumor arising from the follicular cells of the thyroid gland (as does well differentiated thyroid cancer, WDTC), but ATC cells do not retain any of the biological features of the original follicular cells, such as uptake of iodine and synthesis of thyroglo...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2008-12-01 00:00:00
abstract::The presence of islet cell autoantibodies (ICA), and especially of glutamic acid decarboxylase autoantibodies (GAD65Ab), in patients with non-insulin-dependent diabetes mellitus identifies the so-called latent autoimmune diabetes in the adult (LADA). LADA patients have an increased risk for developing insulin deficien...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2003-12-01 00:00:00
abstract::Visualization of cerebral perfusion with Single Photon Emission Computed Tomography (SPET) needs lipophil radiotracers which are able to cross the intact blood-brain-barrier (BBB); moreover local uptake must reflect regional cerebral blood flow. In the last decade many radiopharmaceuticals have been suggested and empl...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::Nodular goiter encompasses a spectrum of diseases from the incidental asyntomatic small solitary nodule to the large intrathoracic goiter causing pressure symptoms as well as functional complaints. The mainstay in the diagnostic evaluation is related to functional and morphological characterization with serum thyroid-...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2010-09-01 00:00:00
abstract::New-onset diabetes after transplantation (NODAT) or posttransplant diabetes mellitus is a frequent metabolic complication of organ transplantation. Diabetes incidence rates among transplant recipients are higher than in the general population. The estimated rates are 9-18% after kidney, 20-33% after liver, 26-40% afte...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2012-09-01 00:00:00
abstract::Neuroendocrine tumours (NET) are relatively rare neoplasms affecting principally the gastroenteropancreatic tract, but with potential ubiquitary location, as the neural crest cells, origin of this group of tumours, are dispersed in various organs and tissues. After the discovery of somatostatin receptors (SSTR) over-e...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2008-09-01 00:00:00
abstract::The major issue currently being faced in the management of prostate cancer is the inability to distinguish between indolent prostate tumors that will not present clinically from more aggressive and metastatic prostate cancers that will impact on men's lives. Only a small proportion of prostate cancers can be accounted...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2012-06-01 00:00:00
abstract::Adrenals are a common site of metastasis for many solid tumors. Adrenal metastases, and related symptoms of adrenal failure, are usually overlooked in clinical practice. This is probably due to the functional compensation of the adrenal glands and to the fact that signs and symptoms of adrenal insufficiency are aspeci...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:1995-03-01 00:00:00
abstract::Adrenal scintigraphy using 131I-6-beta-iodomethyl-19-norcholesterol or 6-methyl-75Se-methyl-19-norcholesterol is a function-dependent imaging method which, in association with high-resolution spatial imaging techniques, plays an essential role in the study of adrenocortical hyperfunction. It can distinguish between bi...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:1995-03-01 00:00:00
abstract:AIM:The aim of this paper was to determine the prevalence of altered sensorium and their determinants in diabetic ketoacidosis (DKA). METHODS:Retrospective review of medical records for diabetic ketoacidosis admissions over a two year period. RESULTS:A total of 94 admissions for DKA in 89 patients were reviewed. Majo...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract::A 49-year-old man presented with a 6-month history of weight loss, muscular weakness, easy fatigue, impotence, decreased visual acuity, campimetry defects. The results of radiologic and endocrine testing disclosed the presence of pituitary dysfunction due to pituitary stalk section caused by a giant suprasellar aneury...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1989-10-01 00:00:00
abstract:BACKGROUND:A limited number of human and animal studies suggest that a relationship exists between phthalates and obesity, although this is not supported by all research. The purpose of this study was to investigate the relationship between Body Mass Index (BMI) and the levels of phthalates in human blood and urine sam...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.16.02295-1
更新日期:2017-03-01 00:00:00
abstract::The characterisation of adrenal lesions is a common radiological dilemma. Incidental adrenal lesions are commonly detected with computed tomography (CT), and lesion characterisation is critical. The prevalence of incidental adrenal lesions has been reported to be 2.3% at autopsy and 0.5-2% with abdominal CT. Such lesi...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Multicellular spheroids represent an interesting experimental model with promising applications in the pre-clinical studies on anticancer drugs. We recently demonstrated that thyroid spheroids recapitulate the features of the original tissues, in either the differentiated and "stem-like" components. Here we ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.17.02610-4
更新日期:2018-03-01 00:00:00
abstract::Previous studies have shown a significant but weak correlation between speed of sound (SOS) and broadband ultrasound attenuation (BUA) in bone, and densitometric bone measurements. These findings indicate that these techniques reflect different properties of bone. We measured SOS and BUA in the os calcis (Achilles, Lu...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00