Abstract:
:According to the literature, the prevalence of papillary thyroid microcarcinoma (PTMC) is increasing. To date, PMTC account for up to 30% of all differentiated thyroid cancers. Patients with PTMC have an excellent prognosis with a normal life expectancy. Because of the differential definitions of the PTMC, the therapeutic approaches of the national Scien-tific Societies have not been standardized. The therapeutic algorithms have to be adjusted with regard to thyroid surgery, radioiodine ablation and thyrotropin-suppressive therapy as well as follow-up. Recently, the Therapy Committee of the European Society of Nuclear Medicine (EANM) has recommended a risk-adapted therapy and follow-up. Risk factors which require a more aggressive therapeutic approach are multifocality, thyroid capsule infiltration, evidence of locoregional or distant metastasis and unfavourable histology. It was the aim of this review to evaluate the current therapeutic concepts in patients with PTMC from a nuclear medicine perspective.
journal_name
Minerva Endocrinoljournal_title
Minerva endocrinologicaauthors
Riemann B,Schober Osubject
Has Abstractpub_date
2009-03-01 00:00:00pages
81-7issue
1eissn
0391-1977issn
1827-1634journal_volume
34pub_type
杂志文章,评审abstract:AIM:The aim of this paper was to determine the prevalence of altered sensorium and their determinants in diabetic ketoacidosis (DKA). METHODS:Retrospective review of medical records for diabetic ketoacidosis admissions over a two year period. RESULTS:A total of 94 admissions for DKA in 89 patients were reviewed. Majo...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract::Multiple endocrine neoplasia type 1 (MEN1; formerly known as Wermer syndrome) is a rare disorder characterized by the combined occurrence of two or more tumors involving parathyroid, pancreatic islets and anterior pituitary glands; some other tumors have also been described. In most cases it is inherited in an autosom...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2013-03-01 00:00:00
abstract::Bariatric surgery has been found to be very useful in treating established type-2 diabetes in obese persons, as well as in borderline diabetics, besides giving a good weight loss. Various modifications of the primary bariatric procedures have been introduced, with differ advantages and better efficacy. Good incretin r...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2016-12-01 00:00:00
abstract::Neuroendocrine tumours (NET) are relatively rare neoplasms affecting principally the gastroenteropancreatic tract, but with potential ubiquitary location, as the neural crest cells, origin of this group of tumours, are dispersed in various organs and tissues. After the discovery of somatostatin receptors (SSTR) over-e...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2008-09-01 00:00:00
abstract::Growth hormone (GH) has been recently approved by the Italian Health Authorities for use in transition patients with childhood onset-growth hormone deficiency (CO-GHD). GH in addition to promote linear growth influences several key metabolic processes. In particular, in the transition period, from late adolescent to e...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:The study evaluates the circadian rhythm of melatonin in relation to sex and age and identified contemporary alterations in the secreton of some hypophyseal hormones, suggesting that melatonin may exert a modulatory action on the latter. METHODS:The melatonin metabolite (6-hydroxymelatonin sulfate) was assa...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2002-06-01 00:00:00
abstract::We treated with PEI 81 patients carriers of autonomous thyroid nodule, 65 toxic and 16 non toxic, all with undetectable serum TSH and suppressed extranodular tissue on scintigraphy. The treatment schedule was: 1-2 sessions per week, 1-8 ml per session, 3-13 sessions in total, In relation to the size and the therapeuti...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract:AIM:Patients with differentiated thyroid carcinoma (DTC) are closely monitored during the first decade after diagnosis. At intervals of 1-2 years withdrawal of suppressive doses of T(4) is recommended in order to check thyroglobulin (Tg) levels under increased TSH. T(4) therapy is usually withdrawn for 5 weeks (during ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2006-06-01 00:00:00
abstract::Visualization of cerebral perfusion with Single Photon Emission Computed Tomography (SPET) needs lipophil radiotracers which are able to cross the intact blood-brain-barrier (BBB); moreover local uptake must reflect regional cerebral blood flow. In the last decade many radiopharmaceuticals have been suggested and empl...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::The characterisation of adrenal lesions is a common radiological dilemma. Incidental adrenal lesions are commonly detected with computed tomography (CT), and lesion characterisation is critical. The prevalence of incidental adrenal lesions has been reported to be 2.3% at autopsy and 0.5-2% with abdominal CT. Such lesi...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2009-06-01 00:00:00
abstract::Diabetological care in pre-gestational (preGDM) and gestational (GDM) pregnant diabetic is an indispensable factor for the reduction of risk of mother, fetus and newborn complications. The adoption of an intensified therapy, aiming at maintaining almost normal glycemic values, and the improvement in fetal monitoring h...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:1994-06-01 00:00:00
abstract::Sex steroids are essential for reproduction and development in animals and humans, and sex steroids also play an important role in neuroprotection following brain injury. New data indicate that sex-specific responses to brain injury occur at the cellular and molecular levels. This review summarizes the current underst...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2010-06-01 00:00:00
abstract::Subclinical hypothyroidism - i.e., a condition characterized by serum TSH concentrations above the normal reference range in the presence of normal serum T4 levels - affects 4 to 20% of the population living in iodine-sufficient areas. The present work reviews the clinical challenges regarding, on the one hand, the si...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.20.03176-4
更新日期:2020-08-03 00:00:00
abstract::Acromegaly is a rare disease characterized by high levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1). The excess of GH leads to the development of different manifestations in different organs, from subtle signs in the bones and soft tissues to the development of respiratory and cardiac insufficien...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:10.23736/S0391-1977.18.02930-9
更新日期:2019-06-01 00:00:00
abstract::Growth hormone-releasing hormone (GHRH) is a hypothalamic hormone that is essential for normal expansion of the somatotrope lineage during pituitary development. Decreased GHRH secretion and/or action leads to impairment of this process and somatotrope hypoplasia in both humans and experimental animals. Excessive GHRH...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2002-12-01 00:00:00
abstract::The use of GH treatment in subjects with a GH deficiency has led to contrasting results concerning its impact to develop thyroid hyperfunction, whereas many others have underlined the possible onset of hypothyroidism. A number of studies have been carried out over short periods in subjects with multiple tropin deficie...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Loss of weight in obese patients, both hypertensive and normotensive, causes a fall in blood pressure (BP) through a mechanism which is still not fully understood. The effects of a low-sodium low-energy diet on BP were assessed in 20 obese subjects (15 M and 5 F; age 26-65 years), 11 of whom were normotensive and 9 hy...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract::Congenital hypogonadotropic hypogonadism (CHH) is a rare disease characterized by delayed/absent puberty and infertility due to an inadequate secretion or action of gonadotrophin-releasing hormone (GnRH), with an otherwise structurally and functionally normal hypothalamic-pituitary-gonadal (HPG) axis. CHH is genetical...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2016-06-01 00:00:00
abstract::One hundred children (4.1 +/- 1.9 years) were examined: 31 of type I diabetic mothers, 25 of type II diabetic mothers and 44 of gestational diabetic mothers. The fetal body weight index at delivery was determined according to Babson. The weight/height index was determined according to Tunner's Centiles, when the child...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract:AIM:The aim of this paper was to compare serum high sensitivity C-reactive protein (HsCRP) levels and carotid artery intima-media thickness (CIMT) of patients with impaired glucose tolerance (IGT) or impaired fasting glucose (IFG) with that in control subjects. METHODS:Ninety-six subjects with prediabetes, 48 with IFG...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2013-09-01 00:00:00
abstract::A 49 year-old woman with anaplastic thyroid carcinoma came, for the first time, to our clinic with an enlarged supraclavicular lymph node. Ten years earlier she received a diagnosis of benign nodular goiter and has been followed up with ultrasonography, which never demonstrated any enlargement of her thyroid nodule an...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract::Loss of estrogens or androgens causes bone loss by increasing the rate of bone remodeling, and also causes an imbalance between resorption and formation by prolonging the lifespan of osteoclasts and shortening the lifespan of osteoblasts. Conversely, treatment with androgens, as well as estrogens, maintains cancellous...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND:Whether Doppler ultrasonography (DU) may be of help in characterizing thyroid nodes is still under debate: both good and unsatisfactory results have been claimed, either in evaluating the presence of malignancy or in identifying hyperfunctional structures. METHODS:In this paper, the scintigraphic and Dopple...
journal_title:Minerva endocrinologica
pub_type: 临床试验,杂志文章
doi:
更新日期:1999-03-01 00:00:00
abstract::Pregnancy in women with a diagnosis of Cushing' syndrome (CS) is an extremely rare event and its diagnosis and treatment are a real medical challenge. During pregnancy, the hypothalamus-pituitary-adrenal axis undergoes major changes leading to a significant increase in plasma cortisol levels throughout gestation. The ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:10.23736/S0391-1977.18.02803-1
更新日期:2018-12-01 00:00:00
abstract::For decades gross-total resection was the preferred treatment option in childhood-onset craniopharyngioma, assuming that radical strategies at the time of initial diagnosis and treatment would result in cure. Recent reports on long-term prognosis, novel treatment approaches, and molecular genetics provide new insights...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,meta分析,评审
doi:10.23736/S0391-1977.17.02615-3
更新日期:2017-12-01 00:00:00
abstract::A number of studies have been carried out over the past year to characterise the physiological functions and possible therapeutic applications of somatostatin (sst). Somatostatin is one of the most widespread peptides in the body and it fulfils a very wide spectrum of actions in the various organs and tissues. The aim...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2001-09-01 00:00:00
abstract::Steroid hormones mediate pleiotropic cellular processes involved in metabolism, cellular proliferation, and differentiation. The ability of the cell to respond to its hormonal environment is transduced by nuclear receptors (NRs) that bind both hormone and DNA. Hence, NRs represent a link between the external hormonal ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:
更新日期:2002-03-01 00:00:00
abstract::Central adrenal insufficiency (AI) represents a life-threatening disorder that results from a reduced cortisol production due to an impairment production of adrenocorticotropic hormone (ACTH). In particular, secondary AI results from pituitary disease that impedes the release of ACTH, while tertiary AI is caused from ...
journal_title:Minerva endocrinologica
pub_type: 杂志文章,评审
doi:10.23736/S0391-1977.17.02701-8
更新日期:2018-06-01 00:00:00
abstract::Very-low-calorie ketogenic diet (VLCKD) is a promising lifestyle intervention for the management of overweight and obesity. It is characterized by a restriction of both calories and carbohydrates, while assuring the adequate proteins, fats and micronutrients intake. Significant results in terms of excess body weight l...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.20.03356-8
更新日期:2020-11-19 00:00:00
abstract:BACKGROUND:This study evaluates the effectiveness of continuous glucose monitoring (CGM) in diabetes patients who were on routine dialysis. METHODS:Literature search was conducted in electronic databases and studies were selected by following precise eligibility criteria. Random-effects meta-analyses were performed to...
journal_title:Minerva endocrinologica
pub_type: 杂志文章
doi:10.23736/S0391-1977.20.03284-8
更新日期:2020-12-03 00:00:00