The management of severe acute necrotising pancreatitis: an evidence-based review of the literature.

abstract：OBJECTIVE:Cytokeratin 19 (CK19) is a specific cytoskeletal structure for alveolar epithelium. We hypothesized that the levels of CK19 fragments in bronchoalveolar lavage (BAL) fluid could serve as an index of epithelial injury and as a prognosis marker in patients with acute lung injury (ALI) or acute respiratory distr...

journal_title：Intensive care medicine

authors： Stern JB,Paugam C,Validire P,Adle-Biassette H,Jaffré S,Dehoux M,Crestani B

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:We compared hemodynamic and biological effects of the Cascade system, which uses very high volume hemofiltration (HVHF) (120 mL kg(-1) h(-1)), with those of usual care in patients with septic shock. METHODS:Multicenter, prospective, randomized, open-label trial in three intensive care units (ICU). Adults with ...

journal_title：Intensive care medicine

authors： Quenot JP,Binquet C,Vinsonneau C,Barbar SD,Vinault S,Deckert V,Lemaire S,Hassain AA,Bruyère R,Souweine B,Lagrost L,Adrie C

更新日期：2015-12-01 00:00:00

abstract：:In 16 patients with multiple injuries the effect of parenteral administration of a fat emulsion on the pulmonary vascular system has been studied. Using the Hewlett Packard 5600 A Intensive Care System, which allows vital parameters to be sampled at a rate of two values per min, pulmonary artery pressure (PAP) was mon...

journal_title：Intensive care medicine

authors： van Deyk K,Hempel V,Münch F,Kopp M,Graf H,Epple E

更新日期：1983-01-01 00:00:00

abstract：PURPOSE:Because non-invasive mechanical ventilation (NIV) is increasingly used, new devices, both ventilators and interfaces, have been continuously proposed for clinical use in recent years. To provide the clinicians with valuable information about ventilators and interfaces for NIV, several bench studies evaluating a...

journal_title：Intensive care medicine

authors： Olivieri C,Costa R,Conti G,Navalesi P

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To assess the ability of quantitative pupillometry [using the Neurological Pupil index (NPi)] to predict an unfavorable neurological outcome after cardiac arrest (CA). METHODS:We performed a prospective international multicenter study (10 centers) in adult comatose CA patients. Quantitative NPi and standard ma...

journal_title：Intensive care medicine

authors： Oddo M,Sandroni C,Citerio G,Miroz JP,Horn J,Rundgren M,Cariou A,Payen JF,Storm C,Stammet P,Taccone FS

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of some acid-base abnormalities on blood capacity of transporting CO(2). DESIGN:Prospective study. SETTING:General and Cardiosurgical ICUs of a University hospital. PATIENTS:Six groups of ten patients characterized by: metabolic alkalosis; respiratory alkalosis; absence of acid-b...

journal_title：Intensive care medicine

authors： Cavaliere F,Antonelli M,Arcangeli A,Conti G,Pennisi MA,Proietti R

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of terlipressin on oxygenation, PaO2/FIO2, heart rate, mean arterial pressure, and mortality in children with septic shock refractory to high doses of dopamine/dobutamine and adrenaline. DESIGN AND SETTING:A randomized, nonblind study in the pediatric intensive care unit of a universit...

journal_title：Intensive care medicine

authors： Yildizdas D,Yapicioglu H,Celik U,Sertdemir Y,Alhan E

更新日期：2008-03-01 00:00:00

abstract：PURPOSE:Although low doses of oxygen (FiO2 <0.50) are considered nontoxic, recent studies have shown that even lower doses increase pulmonary inflammatory mediators. We aimed to evaluate the acute effects of reducing FiO2 on pulmonary inflammation in mechanically ventilated patients without respiratory failure. METHOD...

journal_title：Intensive care medicine

authors： Fernandez R,Gili G,Villagra A,Lopez-Aguilar J,Artigas A

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:Frail patients are known to experience poor outcomes. Nevertheless, we know less about how frailty manifests itself in patients' physiology during critical illness and how it affects resource use in intensive care units (ICU). We aimed to assess the association of frailty with short-term outcomes and organ supp...

journal_title：Intensive care medicine

authors： Zampieri FG,Iwashyna TJ,Viglianti EM,Taniguchi LU,Viana WN,Costa R,Corrêa TD,Moreira CEN,Maia MO,Moralez GM,Lisboa T,Ferez MA,Freitas CEF,de Carvalho CB,Mazza BF,Lima MFA,Ramos GV,Silva AR,Bozza FA,Salluh JIF,Soar

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:Motion-mode (MM) echography allows precise measurement of diaphragmatic excursion when the ultrasound beam is parallel to the diaphragmatic displacement. However, proper alignment is difficult to obtain in patients after cardiac surgery; thus, measurements might be inaccurate. A new imaging modality named the a...

journal_title：Intensive care medicine

authors： Pasero D,Koeltz A,Placido R,Fontes Lima M,Haun O,Rienzo M,Marrache D,Pirracchio R,Safran D,Cholley B

更新日期：2015-04-01 00:00:00

abstract：: ...

journal_title：Intensive care medicine

authors： Monnet X,Saugel B

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:To determine the steady-state plasma and epithelial lining fluid (ELF) concentrations of ceftazidime administered in continuous infusion to critically ill patients with severe nosocomial pneumonia. DESIGN:Prospective, open-label study. SETTING:An intensive care unit and research ward in a university hospita...

journal_title：Intensive care medicine

authors： Boselli E,Breilh D,Rimmelé T,Poupelin JC,Saux MC,Chassard D,Allaouchiche B

更新日期：2004-05-01 00:00:00

abstract：: ...

journal_title：Intensive care medicine

authors： Varkila MRJ,Cremer OL

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:Critical illness increases the tendency to both coagulation and bleeding, complicating anticoagulation for continuous renal replacement therapy (CRRT). We analyzed strategies for anticoagulation in CRRT concerning implementation, efficacy and safety to provide evidence-based recommendations for clinical prac...

journal_title：Intensive care medicine

authors： Oudemans-van Straaten HM,Wester JPJ,de Pont ACJM,Schetz MRC

更新日期：2006-02-01 00:00:00

abstract：PURPOSE:Intensive care unit survivors suffer from prolonged impairment, reduced quality of life, and higher mortality rates after discharge compared to the general population. Socioeconomic status may play a partial but important role in mortality and recovery. Therefore, the detection of factors that are responsible f...

journal_title：Intensive care medicine

authors： Bastian K,Hollinger A,Mebazaa A,Azoulay E,Féliot E,Chevreul K,Fournier MC,Guidet B,Michel M,Montravers P,Pili-Floury S,Sonneville R,Siegemund M,Gayat E,FROG-ICU Study Investigators.

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To determine the incidence rates of hospital acquired infections (HAI) during the first 14 days after ICU discharge after treatment during ICU-stay with Selective Decontamination of the Digestive tract (SDD), Selective Oropharyngeal Decontamination (SOD) or Standard Care (SC). DESIGN:Prospective observationa...

journal_title：Intensive care medicine

authors： de Smet AM,Hopmans TE,Minderhoud AL,Blok HE,Gossink-Franssen A,Bernards AT,Bonten MJ

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:Short-latency somatosensory evoked potential (SSEP) monitoring has been reported to be useful in predicting neurological outcome in patients with cardiac arrest and hypoxic-ischemic encephalopathy. To obtain the immediate data of SSEP and evaluate the relationship between the presence of cortical activity and...

journal_title：Intensive care medicine

authors： Nakabayashi M,Kurokawa A,Yamamoto Y

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:To measure the effect of intense neuromuscular blockade (NMB) on oxygen consumption (VO(2)) in deeply sedated and mechanically ventilated children on the first day after complex congenital cardiac surgery. DESIGN:Prospective clinical interventional study. SETTING:Pediatric intensive care unit of an universi...

journal_title：Intensive care medicine

authors： Lemson J,Driessen JJ,van der Hoeven JG

更新日期：2008-12-01 00:00:00

abstract：:Although colitis is often seen in critically all patients who have received multiple broad-spectrum antibiotics, there are no reports describing severe sepsis as a result of Clostridium difficile infection. We describe three cases of severe sepsis with local intestinal Clostridium difficile infection as the only ident...

journal_title：Intensive care medicine

authors： Lowenkron SE,Waxner J,Khullar P,Ilowite JS,Niederman MS,Fein AM

更新日期：1996-09-01 00:00:00

abstract：PURPOSE:Hypoxic hepatitis (HH) is a form of hepatic injury following arterial hypoxemia, ischemia, and passive congestion of the liver. We investigated the incidence and the prognostic implications of HH in the medical intensive care unit (ICU). METHODS:A total of 1,066 consecutive ICU admissions at three medical ICUs...

journal_title：Intensive care medicine

authors： Fuhrmann V,Kneidinger N,Herkner H,Heinz G,Nikfardjam M,Bojic A,Schellongowski P,Angermayr B,Schöniger-Hekele M,Madl C,Schenk P

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:To define the different types of costs incurred in the care of critically ill patients and to describe some of the most commonly used methods for measuring and allocating these costs. DESIGN:Literature review. Definitions for opportunity, direct and indirect, fixed, variable, marginal, and total costs are de...

journal_title：Intensive care medicine

authors： Jegers M,Edbrooke DL,Hibbert CL,Chalfin DB,Burchardi H

更新日期：2002-06-01 00:00:00

abstract：PURPOSE:Sepsis is a major health burden worldwide. Preclinical investigations in animals and retrospective studies in patients have suggested that inhibition of platelets may improve the outcome of sepsis. In this study we investigated whether chronic antiplatelet therapy impacts on the presentation and outcome of seps...

journal_title：Intensive care medicine

authors： Wiewel MA,de Stoppelaar SF,van Vught LA,Frencken JF,Hoogendijk AJ,Klein Klouwenberg PMC,Horn J,Bonten MJ,Zwinderman AH,Cremer OL,Schultz MJ,van der Poll T,MARS Consortium.

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:Biomarkers allowing accurate early staging of septic shock patients are lacking despite their obvious interest for patient management. Experimental models of septic shock in mouse previously noted a decrease in dendritic cell numbers. The aim of the study was to find a rapid reproducible biological test for a...

journal_title：Intensive care medicine

authors： Guisset O,Dilhuydy MS,Thiébaut R,Lefèvre J,Camou F,Sarrat A,Gabinski C,Moreau JF,Blanco P

更新日期：2007-01-01 00:00:00

abstract：:An 18-month-old male infant presented with hypoglycemic coma and clinical signs of bronchopneumonia. He was suspected of suffering from septic shock. The patient progressed to irreversible multiple organ failure before the diagnosis of adrenal crisis was established. Plasma levels of ACTH and cortisol remained undetec...

journal_title：Intensive care medicine

authors： Fischer JE,Stallmach T,Fanconi S

更新日期：2000-01-01 00:00:00

abstract：:We studied the effect of thiopental loading during resuscitation of 53 patients following cardiopulmonary arrest and compared the outcome with that found in 54 patients treated conventionally in the 30 previous months. Thiopental therapy (10 mg/kg i.v.) was begun within 30 min of the arrest once hemodynamic stability ...

journal_title：Intensive care medicine

authors： Monsalve F,Rucabado L,Ruano M,Cuñat J,Lacueva V,Viñuales A

更新日期：1987-01-01 00:00:00

abstract：:Peritoneal dialysis was used in experimental lactic acidosis caused by hypoxia for the removal of endogenous lactate. Two types of dialysis fluid, with and without vasodilator sodium nitroprusside, added intraperitoneally were used. The addition of sodium nitroprusside increased peritoneal the clearance of lactate as ...

journal_title：Intensive care medicine

authors： Breborowicz A,Szulc R

更新日期：1981-01-01 00:00:00

abstract：OBJECTIVE:To present the efficacy and tolerability of a new oral dosage form of the calcium antagonist nitrendipine compared to nifedipine capsules in patients with hypertensive emergency. DESIGN:Multicenter randomized double blind clinical study. SETTING:23 study centres (hospitals) in Germany. PATIENTS:161 patient...

journal_title：Intensive care medicine

authors： Rohr G,Reimnitz P,Blanke P

更新日期：1994-01-01 00:00:00

abstract：:During a 3-year period, a clinical diagnosis of invasive candidosis was made in 8 out of 2054 consecutive surgical intensive care unit (ICU) patients. These patients were retrospectively matched with 16 control patients who underwent similar surgical procedures and had a similar clinical course except for negative Can...

journal_title：Intensive care medicine

authors： Lepper PM,Wiedeck H,Geldner G,Essig A,Trautmann M

更新日期：2001-05-01 00:00:00

abstract：:We studied the influence of ventilatory frequency (1-5 Hz), tidal volume, lung volume and body position on the end-expiratory alveolar-to-tracheal pressure difference during high-frequency jet ventilation (HFJV) in Yorkshire piglets. The animals were anesthetized and paralysed. Alveolar pressure was estimated with the...

journal_title：Intensive care medicine

authors： van Vught AJ,Versprille A,Jansen JR

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:Atracurium besylate and laudanosine cause excitement and seizures when introduced into the central nervous system of laboratory animals. We examined the modulation of lipid-protein interaction in the lipid environment of rat brain synaptosomal plasma membrane (SPM)-bound enzymes as a possible mechanism leadin...

journal_title：Intensive care medicine

authors： Kamper EF,Siafaka J,Stavridis J

更新日期：1998-05-01 00:00:00