Plasma and lung concentrations of ceftazidime administered in continuous infusion to critically ill patients with severe nosocomial pneumonia.

abstract：:The measurement of functional residual capacity (FRC) has assumed new importance in the diagnosis of acute respiratory failure. However few reference values exist for FRC in supine positions for both sexes. We measured the FRC in 100 healthy subjects with the helium dilution closed circuit method in the sitting and su...

journal_title：Intensive care medicine

authors： Ibañez J,Raurich JM

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:The role of critical care pharmacists in the United States has recently been documented; however, little information exists about the role of international critical care pharmacists. The objective of this study was to describe the duties and activities of international pharmacists who practice in critical car...

journal_title：Intensive care medicine

authors： LeBlanc JM,Seoane-Vazquez EC,Arbo TC,Dasta JF

更新日期：2008-03-01 00:00:00

abstract：PURPOSE:To determine the incidence of and risk factors for adverse cardiac events during catecholamine vasopressor therapy in surgical intensive care unit patients with cardiovascular failure. METHODS:The occurrence of any of seven predefined adverse cardiac events (prolonged elevated heart rate, tachyarrhythmia, myoc...

journal_title：Intensive care medicine

authors： Schmittinger CA,Torgersen C,Luckner G,Schröder DC,Lorenz I,Dünser MW

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To measure the effects of rapid permissive hypercapnia on hemodynamics and gas exchange in patients with acute respiratory distress syndrome (ARDS). DESIGN:Prospective study. SETTING:18-bed, medical intensive care unit, university hospital. PATIENTS:11 mechanically ventilated ARDS patients. INTERVENTION:P...

journal_title：Intensive care medicine

authors： Thorens JB,Jolliet P,Ritz M,Chevrolet JC

更新日期：1996-03-01 00:00:00

abstract：:We report the intensive care management of 23 children (age 3-15 years) following orthotopic heart (HT) and combined heart and lung transplantation (HLT) performed at our 2 institutes between February 1985 and August 1989. Cyclosporin A, azathioprine and steroids were given as routine immunosuppression, whilst anti-th...

journal_title：Intensive care medicine

authors： Whitehead B,James I,Helms P,Scott JP,Smyth R,Higenbottam TW,McGoldrick J,English TA,Wallwork J,Elliott M

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that, during high-frequency oscillatory ventilation (HFOV) of pigs with acute lung injury, the oxygenation index (OI = Paw*FIO(2)*100/PaO(2)) is minimal at the lowest continuous distending pressure (Paw), where the physiological shunt fraction is below 0.1 (Paw(optimal)). DESIGN AND SE...

journal_title：Intensive care medicine

authors： van Genderingen HR,van Vught JA,Jansen JR,Duval EL,Markhorst DG,Versprille A

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To identify and reduce medication-prescribing errors by introducing systematic physician education and post-cardiac surgery admission prescription forms. DESIGN:Errors were defined as: incomplete prescriptions; potential adverse drug events (ADEs), i.e. either intercepted or non-intercepted incorrect prescri...

journal_title：Intensive care medicine

authors： Burmester MK,Dionne R,Thiagarajan RR,Laussen PC

更新日期：2008-06-01 00:00:00

abstract：:The reliability of cardiac output estimation by thermodilution during artificial ventilation was studied in anesthetized pigs at the right side of the heart. The estimates exhibited a cyclic modulation related to the ventilation. The amplitude of the modulation was independent of the level of positive end-expiratory p...

journal_title：Intensive care medicine

authors： Jansen JR,Versprille A

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:Extracorporeal life support (ECLS) is used for patients with refractory heart failure with or without respiratory failure. This temporary support is provided by blood pumps which are connected to large vessels. Bleeding episodes are a typical complication in patients with ECLS. Recently, several studies illustr...

journal_title：Intensive care medicine

authors： Heilmann C,Geisen U,Beyersdorf F,Nakamura L,Benk C,Trummer G,Berchtold-Herz M,Schlensak C,Zieger B

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To provide recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza pandemic or mass disaster with a specific focus on essential equipment, pharmaceuticals and supplies. METHODS:Based on a literature review and expert opinion, a Delphi process was use...

journal_title：Intensive care medicine

authors： Sprung CL,Kesecioglu J,European Society of Intensive Care Medicine's Task Force for intensive care unit triage during an influenza epidemic or mass disaster.

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To assess the effect of strict guidelines and a rigorous training program on variability in scoring the revised Acute Physiology and Chronic Health Evaluation (APACHE II). DESIGN AND SETTING:Prospective survey and intervention in the surgical ICU of a university teaching hospital. MEASUREMENTS:Seven experie...

journal_title：Intensive care medicine

authors： Polderman KH,Jorna EM,Girbes AR

更新日期：2001-08-01 00:00:00

abstract：PURPOSE:Clinical examination is often the first step to diagnose shock and estimate cardiac index. In the Simple Intensive Care Studies-I, we assessed the association and diagnostic performance of clinical signs for estimation of cardiac index in critically ill patients. METHODS:In this prospective, single-centre coho...

journal_title：Intensive care medicine

authors： Hiemstra B,Koster G,Wiersema R,Hummel YM,van der Harst P,Snieder H,Eck RJ,Kaufmann T,Scheeren TWL,Perner A,Wetterslev J,de Smet AMGA,Keus F,van der Horst ICC,SICS Study Group.

更新日期：2019-02-01 00:00:00

abstract：:The recording of intratracheal pressure in patients breathing through a tracheostomy tube is marred by methodological problems. In model experiments it has been shown that the introduction of a recording catheter into the tracheostomy tube alters the recorded pressure by as much as 20-40%. To avoid such inaccuracy, a ...

journal_title：Intensive care medicine

authors： Holst M,Striem J,Hedenstierna G

更新日期：1990-01-01 00:00:00

abstract：:The metabolic changes associated with critical illness involve several pathways acting at different steps of the utilization of nutritive substrates. The understanding of the role of these pathways and of their complex regulation has led to the development of new strategies for the metabolic and nutritional management...

journal_title：Intensive care medicine

authors： Biolo G,Grimble G,Preiser JC,Leverve X,Jolliet P,Planas M,Roth E,Wernerman J,Pichard C,European Society of Intensive Care Medicine Working Group on Nutrition and Metabolism.

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of different lung recruitment maneuvers using electric impedance tomography. DESIGN AND SETTING:Experimental study in animal model of acute lung injury in an animal research laboratory. SUBJECTS:Fourteen pigs with saline lavage induced lung injury. INTERVENTIONS:Lung volume, region...

journal_title：Intensive care medicine

authors： Odenstedt H,Lindgren S,Olegård C,Erlandsson K,Lethvall S,Aneman A,Stenqvist O,Lundin S

更新日期：2005-12-01 00:00:00

abstract：:Malaria remains today one of the major health problems in the tropics with increased morbidity and mortality. The most serious complications are caused by Plasmodium falciparum, which, in contrast to the benign malarias, may progress to a life-threatening multi-system disease. Our case concerns a young woman in the 14...

journal_title：Intensive care medicine

authors： Gregorakos L,Sakayianni K,Hroni D,Harizopoulou V,Georgiadou F,Adamidou M

更新日期：1999-07-01 00:00:00

abstract：:Peritoneal dialysis was used in experimental lactic acidosis caused by hypoxia for the removal of endogenous lactate. Two types of dialysis fluid, with and without vasodilator sodium nitroprusside, added intraperitoneally were used. The addition of sodium nitroprusside increased peritoneal the clearance of lactate as ...

journal_title：Intensive care medicine

authors： Breborowicz A,Szulc R

更新日期：1981-01-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of intravenous sildenafil for immediate postoperative pulmonary hypertension (PH) in pediatric patients undergoing congenital heart surgery. METHODS:A double-blind, multicenter, placebo-controlled, dose-ranging, parallel-group trial was conducted. Patients were randomized to...

journal_title：Intensive care medicine

authors： Fraisse A,Butrous G,Taylor MB,Oakes M,Dilleen M,Wessel DL

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To determine the presence of tricuspid regurgitation (TR) in patients affected by acute lung injury (ALI) and the adult respiratory distress syndrome (ARDS) during mechanical ventilation with positive end-expiratory pressure (PEEP). DESIGN:A prospective clinical study. SETTING:10-bed general intensive care ...

journal_title：Intensive care medicine

authors： Artucio H,Hurtado J,Zimet L,de Paula J,Beron M

更新日期：1997-08-01 00:00:00

abstract：PURPOSE:Little is known on the incidence of discomfort during the end-of-life of intensive care unit (ICU) patients and the impact of sedation on such discomfort. The aim of this study was to assess the incidence of discomfort events according to levels of sedation. METHODS:Post-hoc analysis of an observational prospe...

journal_title：Intensive care medicine

authors： Robert R,Le Gouge A,Kentish-Barnes N,Adda M,Audibert J,Barbier F,Bourcier S,Bourenne J,Boyer A,Devaquet J,Grillet G,Guisset O,Hyacinthe AC,Jourdain M,Lerolle N,Lesieur O,Mercier E,Messika J,Renault A,Vinatier I,Az

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:Candida spp. airway colonization could promote development of ventilator-associated pneumonia (VAP) caused by Pseudomonas aeruginosa, a potentially multidrug-resistant (MDR) bacteria, and worsen the outcome of VAP regardless of pathogen. We therefore address the question of the risk of MDR bacteria isolation ...

journal_title：Intensive care medicine

authors： Hamet M,Pavon A,Dalle F,Pechinot A,Prin S,Quenot JP,Charles PE

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:Critical illness increases the tendency to both coagulation and bleeding, complicating anticoagulation for continuous renal replacement therapy (CRRT). We analyzed strategies for anticoagulation in CRRT concerning implementation, efficacy and safety to provide evidence-based recommendations for clinical prac...

journal_title：Intensive care medicine

authors： Oudemans-van Straaten HM,Wester JPJ,de Pont ACJM,Schetz MRC

更新日期：2006-02-01 00:00:00

abstract：:The effect of enteral feeding on O2-consumption (VO2) and CO2-production (VCO2) was studied in 9 ventilator-dependent patients, who were in a stable condition without signs of hypermetabolism. Resting energy expenditure (REE) in postabsorptive state was assessed and enteral feeding was started by continuous drip (480 ...

journal_title：Intensive care medicine

authors： van den Berg B,Stam H

更新日期：1988-01-01 00:00:00

abstract：:In severe status asthmaticus basic medical treatment often fails to improve the patient's condition. Mechanical ventilation in this situation is associated with a high incidence of serious complications. After the bronchodilating effect of moderate-dose magnesium sulfate in asthmatic patients had been demonstrated in ...

journal_title：Intensive care medicine

authors： Sydow M,Crozier TA,Zielmann S,Radke J,Burchardi H

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of basic life support, time to first defibrillation and emergency medical service arrival time on neurologic outcome and expenses for hospital care in patients after cardiac arrest. SETTING:Large urban emergency medical services system and emergency department in a 2000-bed university...

journal_title：Intensive care medicine

authors： Bur A,Kittler H,Sterz F,Holzer M,Eisenburger P,Oschatz E,Kofler J,Laggner AN

更新日期：2001-09-01 00:00:00

abstract：:The goals of management of patients with respiratory failure include improving arterial oxygenation with PEEP and red cell transfusion to maintain oxygen carrying capacity, both of which contribute to improving tissue oxygen delivery. However, standard CPD-stored blood is rapidly depleted of 2,3 diphosphoglycerate (2,...

journal_title：Intensive care medicine

authors： Kahn RC,Zaroulis C,Goetz W,Howland WS

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:In patients with severe sepsis, no randomized clinical trial has tested the concept of de-escalation of empirical antimicrobial therapy. This study aimed to compare the de-escalation strategy with the continuation of an appropriate empirical treatment in those patients. METHODS:This was a multicenter non-bl...

journal_title：Intensive care medicine

authors： Leone M,Bechis C,Baumstarck K,Lefrant JY,Albanèse J,Jaber S,Lepape A,Constantin JM,Papazian L,Bruder N,Allaouchiche B,Bézulier K,Antonini F,Textoris J,Martin C,AZUREA Network Investigators.

更新日期：2014-10-01 00:00:00

abstract：:Pneumonia caused by herpes simplex virus type 1 (HSV1) is rare and occurs in severely immunosuppressed patients. HSV1 can be detected in bronchoalveolar lavage (BAL) from patients presenting with respiratory failure, but its direct effect on disease is difficult to prove. We demonstrate the causative role of HSV1 in t...

journal_title：Intensive care medicine

authors： François-Dufresne A,Garbino J,Ricou B,Wunderli W

更新日期：1997-03-01 00:00:00

abstract：:Factors influencing nitrogen balance during total parenteral nutrition have been investigated in 34 critically ill injured patients studied during the first 6 days after trauma. Basal nitrogen balance was severely negative (-0.26 +/- 0.12 (SD) g X kg-1), but improved consistently during treatment. Nitrogen intake prov...

journal_title：Intensive care medicine

authors： Iapichino G,Radrizzani D,Solca M,Pesenti A,Gattinoni L,Ferro A,Leoni L,Langer M,Vesconi S,Damia G

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:To obtain insight into the occurrence of brain death and the potential for brain dead and controlled non-heart-beating organ donors (CNHB) in patients with traumatic brain injury (TBI), subarachnoid haemorrhage (SAH) and intracerebral haemorrhage (ICH) in a large neurosurgical serving area (2.1 million inhabi...

journal_title：Intensive care medicine

authors： Kompanje EJO,Bakker J,Slieker FJA,IJzermans JNM,Maas AIR

更新日期：2006-02-01 00:00:00