Abstract：
OBJECTIVE:The role of critical care pharmacists in the United States has recently been documented; however, little information exists about the role of international critical care pharmacists. The objective of this study was to describe the duties and activities of international pharmacists who practice in critical care. DESIGN:Web-based survey. SETTING:Hospitals outside of the United States. PARTICIPANTS:International pharmacists with >50% of their time dedicated to critical care. INTERVENTIONS:An invitation to answer the survey was sent to pharmacists via mail, e-mail or newsletter. Pharmacists were requested to answer based on their current practice. The survey was open from November 2004 to November 2005. MEASUREMENTS AND RESULTS:Data were collected on demographics and clinical and non-clinical activities. The final analysis included 168 pharmacists with dedicated critical care responsibilities. Respondents indicated 74.4% attended medical rounds and 54.8% were involved in research. Therapeutic drug monitoring was completed by 72.6% of pharmacists, with the most commonly monitored medications being aminoglycosides and vancomycin. While 41.7% of pharmacists personally dispensed medications, 13% and 8.4% were involved in directly preparing intravenous medications or total parenteral nutrition, respectively. CONCLUSIONS:International critical care pharmacists participate in a wide range of activities from attending ward rounds to dispensing of medications. We hope the broad range of pharmacist activities described herein will increase the involvement of the pharmacist in the critical care team worldwide.
journal_name
Intensive Care Medjournal_title
Intensive care medicineauthors
LeBlanc JM,Seoane-Vazquez EC,Arbo TC,Dasta JFdoi
10.1007/s00134-007-0918-2subject
Has Abstractpub_date
2008-03-01 00:00:00pages
538-42issue
3eissn
0342-4642issn
1432-1238journal_volume
34pub_type
杂志文章abstract：OBJECTIVE:To investigate efficacy and safety of enoxaparin for catheter-related arterial thrombosis in infants with congenital heart disease. DESIGN:Prospective observational study. SETTING:Pediatric Intensive Care and Cardiology Unit at the University Children's Hospital of Zurich. PATIENTS:A cohort of 32[Symbol: s...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-007-0718-8
更新日期：2007-11-01 00:00:00
abstract：:A study was conducted to evaluate repeated intrathecal injections of baclofen, without artificial ventilation, in the treatment of severe tetanus. Ten patients, 5 men and 5 women, with a mean age of 34 +/- 7 years, were included in the study. The dose of baclofen injected was 1000 micrograms between the ages of 16 and...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01709840
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVES:Controversies concerning the pivotal trial and negative results from other Drotrecogin alfa activated (DAA) trials have raised questions about its efficacy in severe sepsis patients. Based on all available evidence, our study aimed to respond to: (1) What is the current probability that DAA is not better tha...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-008-1159-8
更新日期：2008-10-01 00:00:00
abstract：:A randomized study of 30 patients undergoing uncomplicated surgery under spinal anesthesia was conducted to assess the influence of colloids on the kinetics of plasma fibronectin and complement. Both are opsonins of the reticuloendothelial system; moreover fibronectin is concerned with host resistance against septic c...
journal_title：Intensive care medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF01691428
更新日期：1991-01-01 00:00:00
abstract：:The goals of management of patients with respiratory failure include improving arterial oxygenation with PEEP and red cell transfusion to maintain oxygen carrying capacity, both of which contribute to improving tissue oxygen delivery. However, standard CPD-stored blood is rapidly depleted of 2,3 diphosphoglycerate (2,...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF00315364
更新日期：1986-01-01 00:00:00
abstract：OBJECTIVE:To examine the attitudes of the general public regarding who should decide about the withdrawal of life support and to compare these attitudes with those of intensive care personnel. DESIGN:Nationwide postal questionnaire survey. SETTING:Sweden. PARTICIPANTS:One thousand one hundred ninety-six randomly sel...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s001340050987
更新日期：1999-09-01 00:00:00
abstract：: ...
journal_title：Intensive care medicine
pub_type： 信件
doi：10.1007/s00134-018-5420-5
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVE:To derive recommendations for the dosing of commonly used medications in the morbidly obese patient in the ICU. DATA SOURCES:Articles were obtained through computerized searches involving MEDLINE. The bibliographies of retrieved publications and textbooks were reviewed for additional references. STUDY SELEC...
journal_title：Intensive care medicine
pub_type： 杂志文章,评审
doi：10.1007/s00134-003-2059-6
更新日期：2004-01-01 00:00:00
abstract：:A 29-year-old woman suffered a cardiac arrest, due to profound hyperkalaemia, caused by the use of a potassium-containing salt substitute. She was resuscitated, but post-hypoxic brain damage occurred. Some of the sparse literature is reviewed. ...
journal_title：Intensive care medicine
pub_type： 杂志文章,评审
doi：10.1007/BF00255641
更新日期：1988-01-01 00:00:00
abstract：OBJECTIVE:The long-term mortality outcome associated with sepsis and septic shock has not been well defined in a nonselected critically ill population. This study investigated the occurrence and the role of bloodstream infection (BSI) associated sepsis and septic shock at time of intensive care unit (ICU) admission on ...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-004-2544-6
更新日期：2005-02-01 00:00:00
abstract：PURPOSE:Chronic pulmonary hypertension (PH) therapy is poorly investigated in intensive care. Our aim was to evaluate haemodynamic and neuroendocrine effects of the dual endothelin-1 (ET-1) blocker tezosentan in monocrotaline (MCT)-induced PH. METHODS:Male Wistar rats (180-200 g, n = 194) randomly received 60 mg kg(-1...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-012-2484-5
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Peripherally inserted central venous catheters (PICC) have been proposed as an alternative to central venous catheters (CVC). The aim of this study was to determine the thrombosis rate in relation to PICC placement in patients discharged from the intensive care unit (ICU). METHODS:Data of patients admitted ...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-010-2043-x
更新日期：2011-02-01 00:00:00
abstract：: ...
journal_title：Intensive care medicine
pub_type： 信件
doi：10.1007/s00134-018-5180-2
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVE:Both serum levels of tumor necrosis factor-alpha (TNF alpha) and interleukin-6 (IL-6) and blood lactate levels in patients with septic shock have been shown to correlate with prognosis. The aim of the study was to define the relative predictive value of these measures. PATIENTS:38 hospitalized patients with ...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01712155
更新日期：1996-05-01 00:00:00
abstract：OBJECTIVE:To identify factors that predict outcome in patients receiving a Medical Emergency Team review. DESIGN:Prospective observational study. SETTING:Tertiary hospital. PATIENTS:Cohort of 228 patients receiving one or more Medical Emergency Team reviews during daytime hours over a 1-year-period. Control cohort o...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-008-1229-y
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:To assess noise exposure during noninvasive ventilation (NIV) with different types of interface (helmet, nasal, and facial masks). SUBJECTS AND METHODS:Ten "naive" healthy volunteers underwent NIV at pressure support levels of 10 and 15 cmH2O with: (a) helmet, (b) helmet equipped with HME filters at the junc...
journal_title：Intensive care medicine
pub_type： 临床试验,杂志文章
doi：10.1007/s00134-004-2347-9
更新日期：2004-09-01 00:00:00
abstract：OBJECTIVE:To investigate plasma high-mobility group box 1 protein (HMGB1) concentration and its relationship with organ dysfunction and outcome in septic shock patients. DESIGN AND SETTING:Prospective, noninterventional study. Medical adult intensive care unit at a university hospital in France. PATIENTS:42 criticall...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-007-0691-2
更新日期：2007-08-01 00:00:00
abstract：OBJECTIVES:(a) To assess whether differences in lung morphology observed in patients with adult respiratory distress syndrome (ARDS) are associated with differences in cardiorespiratory parameters, lung mechanics, and outcome. (b) To propose a new ARDS Severity Score to identify patients with a high mortality risk. DE...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s001340051317
更新日期：2000-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the nursing time required for difficult-to-wean patients in a dedicated weaning center (WC) and to examine the correlation of the nursing time with nursing workload (NW) scores and with clinical severity and dependency. SETTING:Four-bed WC of a pulmonary rehabilitation department. INTERVENTION:N...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s001340051249
更新日期：2000-06-01 00:00:00
abstract：OBJECTIVE:We assessed the methodological trial quality of individual randomized controlled studies on chlorhexidine silver sulfadiazine impregnated catheters and the effect on catheter-related infection (CRI). DESIGN:Only the studies identified in the Medline database from 1966 to December 2001 were considered, abstra...
journal_title：Intensive care medicine
pub_type： 杂志文章,meta分析
doi：10.1007/s00134-003-1646-x
更新日期：2003-03-01 00:00:00
abstract：:Optimal fluid management is one of the main challenges in the care of the critically ill. However, the physiological parameters that are commonly monitored and used to guide fluid management are often inadequate and even misleading. From 1987 to 1989 we published four experimental studies which described a method for ...
journal_title：Intensive care medicine
pub_type： 杂志文章,评审
doi：10.1007/s00134-014-3285-9
更新日期：2014-06-01 00:00:00
abstract：:A 29-year-old woman was admitted to the Rouen University Hospital for attempted suicide by ingestion of a carbamate insecticide (Temik G, containing 10% aldicarb). Cardio-respiratory arrest occurred at the second hour and acute necrotic hemorrhagic pancreatitis on the second day. Further evolution was uneventful, and ...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF02425057
更新日期：1994-01-01 00:00:00
abstract：OBJECTIVES:To analyse the clinical value of procalcitonin (PCT), C-reactive protein (CRP) and leucocyte count in the diagnosis of paediatric sepsis and in the stratification of patients according to severity. DESIGN:Prospective, observational study. SETTING:Paediatric intensive care unit (PICU). PATIENTS:Ninety-four...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-006-0509-7
更新日期：2007-03-01 00:00:00
abstract：:In oleic acid-induced pulmonary oedema (OAPO) sequential intrapulmonary fluid accumulation occurs leading to different expiratory flow pattern in dependent lung regions. The potential effects on efficacy of high-frequency jet ventilation (HFJV, f = 3 Hz, I: E = 0.43, FiO2 = 0.4) were studied and compared with continuo...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF00295986
更新日期：1989-01-01 00:00:00
abstract：:The effects of continuous and supplementary bolus dose administration of etomidate have been investigated in ten artificially ventilated patients in traumatic coma. Continuous infusion of etomidate (5-25 micrograms/kg/min) proved to be a practical and safe means of sedating these patients and appeared to control moder...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01692549
更新日期：1983-01-01 00:00:00
abstract：OBJECTIVES:To establish priorities for research in critical care medicine in the UK using survey and nominal group (NG) techniques. DESIGN:The senior doctor and nurse from 325 intensive care units (ICUs) in the UK were invited to contribute up to ten research questions relevant to intensive care organisation, practice...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s001340000628
更新日期：2000-10-01 00:00:00
abstract：OBJECTIVE:To determine the reliability of estimating arterial CO(2) pressure (PaCO(2)) using a recently introduced transcutaneous CO(2) pressure (PtcCO(2)) monitor in severe obese patients. DESIGN:Observational and interventional study. SETTING:District hospital with respiratory ward and bariatric surgery unit. PATI...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/s00134-008-1078-8
更新日期：2008-07-01 00:00:00
abstract：PURPOSE:Motivated by a new randomized trial (the PEPTIC trial) that raised the issue of an increase in mortality with proton pump inhibitors (PPIs) relative to histamine-2 receptor antagonists (H2RAs), we updated our prior systematic review and network meta-analysis (NMA) addressing the impact of pharmacological gastro...
journal_title：Intensive care medicine
pub_type： 杂志文章,评审
doi：10.1007/s00134-020-06209-w
更新日期：2020-11-01 00:00:00
abstract：:In severe status asthmaticus basic medical treatment often fails to improve the patient's condition. Mechanical ventilation in this situation is associated with a high incidence of serious complications. After the bronchodilating effect of moderate-dose magnesium sulfate in asthmatic patients had been demonstrated in ...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01711089
更新日期：1993-01-01 00:00:00
abstract：OBJECTIVE:To compare some of the confirmatory investigations of brain death with clinical criteria in order to achieve the most sensitive and accurate diagnosis of brain death. DESIGN:All patients with isolated brain lesions and Glasgow Coma Scale (GCS) = 3 were subjected to neurological examination after ruling out h...
journal_title：Intensive care medicine
pub_type： 杂志文章
doi：10.1007/BF01711544
更新日期：1995-08-01 00:00:00
