The relationship between methodological trial quality and the effects of impregnated central venous catheters.

abstract：OBJECTIVE:To assess acute cardiorespiratory effects of recruitment manoeuvres in experimental acute lung injury. DESIGN:Experimental study in animal models of acute lung injury. SETTING:Experimental laboratory at a University Medical Centre. ANIMALS:Ten pigs with bronchoalveolar lavage and eight pigs with endotoxin-...

journal_title：Intensive care medicine

authors： Odenstedt H,Aneman A,Kárason S,Stenqvist O,Lundin S

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:The aim of this prospective study was to evaluate the value of sinus echography results to directly indicate a transnasal puncture in intubated patients with suspicion of nosocomial maxillary sinusitis. DESIGN:prospective clinical investigation. SETTING:medical intensive care unit. PATIENTS:sixty patients ...

journal_title：Intensive care medicine

authors： Vargas F,Bui HN,Boyer A,Bébear CM,Lacher-Fougére S,De-Barbeyrac BM,Salmi LR,Traissac L,Gbikpi-Benissan G,Gruson D,Hilbert G

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To document the costs and outcomes of the various forms of the septic syndromes [systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis, septic shock), particularly those associated with infection acquired in an intensive care unit (ICU). DESIGN:Prospective data collection for all septic patie...

journal_title：Intensive care medicine

authors： Brun-Buisson C,Roudot-Thoraval F,Girou E,Grenier-Sennelier C,Durand-Zaleski I

更新日期：2003-09-01 00:00:00

abstract：PURPOSE:Frail patients are known to experience poor outcomes. Nevertheless, we know less about how frailty manifests itself in patients' physiology during critical illness and how it affects resource use in intensive care units (ICU). We aimed to assess the association of frailty with short-term outcomes and organ supp...

journal_title：Intensive care medicine

authors： Zampieri FG,Iwashyna TJ,Viglianti EM,Taniguchi LU,Viana WN,Costa R,Corrêa TD,Moreira CEN,Maia MO,Moralez GM,Lisboa T,Ferez MA,Freitas CEF,de Carvalho CB,Mazza BF,Lima MFA,Ramos GV,Silva AR,Bozza FA,Salluh JIF,Soar

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:To study whether transient hyperglycemia adversely affects cerebral energy metabolism in patients with severe traumatic brain lesions. DESIGN AND SETTING:Prospective, nonrandomized study in the neurosurgical intensive care unit of a university hospital. PATIENTS:108 patients treated for severe traumatic bra...

journal_title：Intensive care medicine

authors： Diaz-Parejo P,Ståhl N,Xu W,Reinstrup P,Ungerstedt U,Nordström CH

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To describe Enterococcus faecalis colonisation and endocarditis in 5 intensive care patients after treatment with selective decontamination (SDD). SETTING:Intensive care unit (ICU) in a general hospital. PATIENTS:The patients were admitted to the ICU because of adult respiratory distress syndrome, polytraum...

journal_title：Intensive care medicine

authors： Sijpkens YW,Buurke EJ,Ulrich C,van Asselt GJ

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVES:To compare the effects of norepinephrine and dobutamine to epinephrine on hemodynamics, lactate metabolism, and gastric tonometric variables in hyperdynamic dopamine-resistant septic shock. DESIGN:A prospective, intervention, randomized clinical trial. SETTING:Adult medical/surgical intensive care unit in ...

journal_title：Intensive care medicine

authors： Levy B,Bollaert PE,Charpentier C,Nace L,Audibert G,Bauer P,Nabet P,Larcan A

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:Candida spp. airway colonization could promote development of ventilator-associated pneumonia (VAP) caused by Pseudomonas aeruginosa, a potentially multidrug-resistant (MDR) bacteria, and worsen the outcome of VAP regardless of pathogen. We therefore address the question of the risk of MDR bacteria isolation ...

journal_title：Intensive care medicine

authors： Hamet M,Pavon A,Dalle F,Pechinot A,Prin S,Quenot JP,Charles PE

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:We describe a patient with a prolonged and severe hypercapnia occurring during an episode of status asthmaticus induced by ophthalmic instillation of carteolol. SETTING:Prehospital Emergency Medical Service and Pulmonary Intensive Care Unit in a university hospital. PATIENT:A 35-year-old female developed an...

journal_title：Intensive care medicine

authors： Adnet F,Plaisance P,Borron SW,Levy A,Payen D

更新日期：1998-12-01 00:00:00

abstract：PURPOSE:Little evidence of increased thrombotic risk is available in COVID-19 patients. Our purpose was to assess thrombotic risk in severe forms of SARS-CoV-2 infection. METHODS:All patients referred to 4 intensive care units (ICUs) from two centers of a French tertiary hospital for acute respiratory distress syndrom...

journal_title：Intensive care medicine

authors： Helms J,Tacquard C,Severac F,Leonard-Lorant I,Ohana M,Delabranche X,Merdji H,Clere-Jehl R,Schenck M,Fagot Gandet F,Fafi-Kremer S,Castelain V,Schneider F,Grunebaum L,Anglés-Cano E,Sattler L,Mertes PM,Meziani F,CRICS TR

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:Reporting neurodevelopmental outcome of 8-year-old children treated with neonatal extracorporeal membrane oxygenation (ECMO). METHODS:In a follow-up study in 135 8-year-old children who received neonatal ECMO between 1996 and 2001 we assessed intelligence (Revised Amsterdam Intelligence Test), concentration (B...

journal_title：Intensive care medicine

authors： Madderom MJ,Reuser JJ,Utens EM,van Rosmalen J,Raets M,Govaert P,Steiner K,Gischler SJ,Tibboel D,van Heijst AF,Ijsselstijn H

更新日期：2013-09-01 00:00:00

abstract：:Arterial blood ketone body ratio, reflecting hepatic mitochondrial redox state, was measured in 26 brain-dead patients who were hypotensive but hemodynamically stable. All of them had substantially normal hepatic function. In 18 of the patients, blood ketone body ratio was maintained within the normal range in spite o...

journal_title：Intensive care medicine

authors： Nakatani T,Ishikawa Y,Kobayashi K,Ozawa K

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To report the first case of ARDS in children treated with nitric oxide (NO) inhalation. METHODS:A 13-months infant presented with BPD and severe hypoxemia related to RSV infection and ARDS. Inhaled NO was delivered in the ventilatory circuit of a continuous flow ventilator (Babylog 8000, Dräger) in a concent...

journal_title：Intensive care medicine

authors： Leclerc F,Riou Y,Martinot A,Storme L,Hue V,Flurin V,Deschildre A,Sadik A

更新日期：1994-08-01 00:00:00

abstract：:We report a case of fatal septic shock, with hyperlactatemia and blood cultures positive for Streptococcus pneumoniae, in a 70-year-old patient. On two occasions (5 days, and 2 days before the patient's death), the relationship between oxygen delivery (DO2) and consumption (VO2) was examined in conjunction with two pr...

journal_title：Intensive care medicine

authors： Gallet D,Goudable J,Vedrinne JM,Viale JP,Annat G

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:A closed suction system (CS) maintains connection with the mechanical ventilator during tracheal suctioning and is claimed to limit loss in lung volume and oxygenation. We compared changes in lung volume, oxygenation, airway pressure and hemodynamics during endotracheal suctioning performed with CS and with a...

journal_title：Intensive care medicine

authors： Cereda M,Villa F,Colombo E,Greco G,Nacoti M,Pesenti A

更新日期：2001-04-01 00:00:00

abstract：:A rapid method for the bedside measurement of plasma, intracellular and whole blood lactates is described. The paper described a new method of measuring the L-lactate content of blood using an apparatus ("Lactate Analyzer 640", manufactured by Roche Bio-electronics, Basel) previously designed for this purpose but usin...

journal_title：Intensive care medicine

authors： Piquard F,Schaefer A,Dellenbach P,Haberey P

更新日期：1980-11-01 00:00:00

abstract：OBJECTIVE:To assess the value of the diagnosis of overt disseminated intravascular coagulation (DIC) according to the International Society on Thrombosis and Haemostasis (ISTH) criteria and that of the parameters included in the ISTH score for overt DIC in predicting day 28 mortality in intensive care patients. Also, t...

journal_title：Intensive care medicine

authors： Sivula M,Tallgren M,Pettilä V

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To assess the role of antipseudomonal agents on Pseudomonas aeruginosa colonization and acquisition of resistance. DESIGN:Prospective cohort study. SETTING:Two medical intensive care units. PATIENTS AND PARTICIPANTS:346 patients admitted for >or= 48 h. INTERVENTION:Analysis of data from an 8-month study c...

journal_title：Intensive care medicine

authors： Martínez JA,Delgado E,Martí S,Marco F,Vila J,Mensa J,Torres A,Codina C,Trilla A,Soriano A,Alquezar A,Castro P,Nicolás JM

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:To determine if the plasma levels of three endothelial-specific proteins, von Willebrand factor (vWF), tissue factor pathway inhibitor (TFPI) and thrombomodulin (TM) may be useful in predicting the development of acute respiratory distress syndrome (ARDS). DESIGN:Blood samples were obtained from normal healt...

journal_title：Intensive care medicine

authors： Bajaj MS,Tricomi SM

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:To study plasma concentrations of interleukin 6 (IL-6) and interleukin 8 (IL-8) in patients with splanchnic hypoxia, as documented by gastric intramucosal measurements (pH-i), during major abdominal surgery and the relationship between IL-6 and IL-8 concentrations and postoperative complications as well as cl...

journal_title：Intensive care medicine

authors： Donati A,Battisti D,Recchioni A,Paoletti P,Conti G,Caporelli S,Adrario E,Pelaia P,Pietropaoli P

更新日期：1998-04-01 00:00:00

abstract：:We analysed the case histories of 22 patients with life threatening asthma retrospectively. Fifteen patients needed mechanical ventilation. Three patients, all of them in cardiac arrest before or at the moment of admission, died. In five patients, halothane therapy was successfully used as a last resort. No major comp...

journal_title：Intensive care medicine

authors： Rosseel P,Lauwers LF,Baute L

更新日期：1985-01-01 00:00:00

abstract：PURPOSE:To develop a liver function-related risk prediction tool to identify acute-on-chronic liver failure patients at greatest risk of in-hospital mortality. METHODS:The LiFe (liver, injury, failure, evaluation) score, was constructed based on the opinions of 157 intensivists within the European Society for Intensiv...

journal_title：Intensive care medicine

authors： Edmark C,McPhail MJW,Bell M,Whitehouse T,Wendon J,Christopher KB

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To evaluate whether soluble triggering receptor expressed on myeloid cells 1 (sTREM-1) in CSF can serve as a biomarker for the presence of bacterial meningitis and outcome in patients with this disease. DESIGN:Retrospective study of diagnostic accuracy. SETTING AND PATIENTS:CSF was collected from 92 adults ...

journal_title：Intensive care medicine

authors： Determann RM,Weisfelt M,de Gans J,van der Ende A,Schultz MJ,van de Beek D

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:To analyze the effects of polymyxin B-immobilized fiber (PMX-F) on bone resorption in septic patients. DESIGN AND SETTING:Observational prospective study in intensive care units of a general hospital. PATIENTS AND PARTICIPANTS:25 patients with severe sepsis and 20 healthy controls. MEASUREMENTS AND RESULTS...

journal_title：Intensive care medicine

authors： Nakamura T,Kawagoe Y,Matsuda T,Koide H

更新日期：2004-09-01 00:00:00

abstract：PURPOSE:Intensive care unit survivors suffer from prolonged impairment, reduced quality of life, and higher mortality rates after discharge compared to the general population. Socioeconomic status may play a partial but important role in mortality and recovery. Therefore, the detection of factors that are responsible f...

journal_title：Intensive care medicine

authors： Bastian K,Hollinger A,Mebazaa A,Azoulay E,Féliot E,Chevreul K,Fournier MC,Guidet B,Michel M,Montravers P,Pili-Floury S,Sonneville R,Siegemund M,Gayat E,FROG-ICU Study Investigators.

更新日期：2018-12-01 00:00:00

abstract：:A young woman with long-standing systemic lupus erythematosus and rheumatic fever presented with deteriorating renal function. She had severe gastritis treated with cimetidine and received methylprednisolone when her blood cultures were repeatedly negative. She developed spontaneous bruising and bleeding from venepunc...

journal_title：Intensive care medicine

authors： Bloxham CA,Carr S,Ryan DW,Kesteven PJ,Bexton RS,Griffiths ID,Richards J

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:The efficacy of interferon gamma therapy in reducing infection and improving outcome from infection in patients sustaining major injury was examined. DESIGN:Randomized double-blind placebo control trial SETTING:Nine level one university affiliated trauma centers in the United States. PATIENTS AND PARTICIPA...

journal_title：Intensive care medicine

authors： Dries DJ

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVES:(1) To demonstrate that metabolic parameters are better indicators of tissue hypoxia than regional and whole oxygen consumption (VO(2)). (2) To compare intramucosal pH (pHi) in different gastrointestinal segments. DESIGN:Prospective, interventional study. SETTING:Research laboratory at a university center....

journal_title：Intensive care medicine

authors： Dubin A,Estenssoro E,Murias G,Canales H,Sottile P,Badie J,Barán M,Pálizas F,Laporte M,Rivas Díaz M

更新日期：2001-12-01 00:00:00

abstract：PURPOSE:Hypoxia-ischemia (HI), as a major cause of fetal brain damage, has long-lasting neurological implications. Therefore, therapeutic interventions that attenuate the neuropathological outcome of HI while also improving the neurofunctional outcome are of paramount clinical importance. The aim of this study was to i...

journal_title：Intensive care medicine

authors： Fathali N,Lekic T,Zhang JH,Tang J

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVES:Controversy over the optimal intravenous fluid for volume resuscitation continues unabated. Our objectives were to characterize the demographics of physicians who prescribe intravenous colloids and determine factors that enter into their decision to choose a colloid. DESIGN:Questionnaire with 61 items. PAR...

journal_title：Intensive care medicine

authors： Miletin MS,Stewart TE,Norton PG

更新日期：2002-07-01 00:00:00