Neurodevelopmental, educational and behavioral outcome at 8 years after neonatal ECMO: a nationwide multicenter study.

Abstract:

PURPOSE:Reporting neurodevelopmental outcome of 8-year-old children treated with neonatal extracorporeal membrane oxygenation (ECMO). METHODS:In a follow-up study in 135 8-year-old children who received neonatal ECMO between 1996 and 2001 we assessed intelligence (Revised Amsterdam Intelligence Test), concentration (Bourdon-Vos test), eye-hand coordination (Developmental Test of Visual-Motor Integration) and behavior (Child Behavior Checklist and Teacher Report Form). RESULTS:Intelligence fell within normal range (mean IQ 99.9, SD 17.7, n = 125) with 91 % of the children following regular education. Significantly more children attended special education (9 %) or received extra support in regular education (39 %) compared with normative data. Slower working speed (χ(2) = 132.36, p < 0.001) and less accuracy (χ(2) = 12.90, p < 0.001) were found on the Bourdon-Vos test (n = 123) compared with normative data. Eye-hand coordination fell within the normal range (mean 97.6, SD 14.3, n = 126); children with congenital diaphragmatic hernia scored lowest but still normally (mean 91.0, SD 16.4, n = 28). Mothers (n = 117) indicated more somatic and attention behavior problems; teachers (n = 115) indicated more somatic, social, thought, aggression and total problems compared with normative data. Mothers indicated more somatic problems than teachers (p = 0.003); teachers reported more attention problems than mothers (p = 0.036; n = 111). CONCLUSIONS:Eight-year-old children treated with neonatal ECMO fall in the normal range of intelligence with problems with concentration and behavior. Long-term follow-up for children treated with neonatal ECMO should focus on early detection of (subtle) learning deficits.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Madderom MJ,Reuser JJ,Utens EM,van Rosmalen J,Raets M,Govaert P,Steiner K,Gischler SJ,Tibboel D,van Heijst AF,Ijsselstijn H

doi

10.1007/s00134-013-2973-1

subject

Has Abstract

pub_date

2013-09-01 00:00:00

pages

1584-93

issue

9

eissn

0342-4642

issn

1432-1238

journal_volume

39

pub_type

杂志文章,多中心研究
  • High-dose intravenous magnesium sulfate in the management of life-threatening status asthmaticus.

    abstract::In severe status asthmaticus basic medical treatment often fails to improve the patient's condition. Mechanical ventilation in this situation is associated with a high incidence of serious complications. After the bronchodilating effect of moderate-dose magnesium sulfate in asthmatic patients had been demonstrated in ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF01711089

    authors: Sydow M,Crozier TA,Zielmann S,Radke J,Burchardi H

    更新日期:1993-01-01 00:00:00

  • Questions to improve family-staff communication in the ICU: a randomized controlled trial.

    abstract:PURPOSE:Relatives of intensive care unit (ICU) patients suffer emotional distress that impairs their ability to acquire the information they need from the staff. We sought to evaluate whether providing relatives with a list of important questions was associated with better comprehension on day 5. METHODS:Randomized, p...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00134-018-5423-2

    authors: Azoulay E,Forel JM,Vinatier I,Truillet R,Renault A,Valade S,Jaber S,Durand-Gasselin J,Schwebel C,Georges H,Merceron S,Cariou A,Moussa M,Hraiech S,Argaud L,Leone M,Curtis JR,Kentish-Barnes N,Jouve E,Papazian L

    更新日期:2018-11-01 00:00:00

  • Time course of lung injury in rat acute pancreatitis.

    abstract:OBJECTIVE:Lung injury is a severe complication of acute pancreatitis that increases the mortality rate of the disease. The pathophysiology of acute pancreatitis has been studied in several experimental models, but the kinetics of pulmonary complications in relation to the pancreatic disease is not completely understood...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-006-0264-9

    authors: Morel DR,Frossard JL,Cikirikcioglu B,Tapponnier M,Pastor CM

    更新日期:2006-11-01 00:00:00

  • Theoretical interactions between ventilator settings and proximal deadspace ventilation during tracheal gas insufflation.

    abstract:OBJECTIVE:To investigate the theoretical interactions between ventilator settings, tracheal gas insufflation (TGI), and alveolar ventilation. DESIGN:We derived differential equations governing compartmental volume changes in a one-compartment model of TGI-assisted ventilation and equations governing gas dilution in th...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF01699238

    authors: Hotchkiss JR Jr,Crooke PS 3rd,Marini JJ

    更新日期:1996-10-01 00:00:00

  • Correction to: COVID-19: a novel coronavirus and a novel challenge for critical care.

    abstract::The original version of this article unfortunately contained a mistake. ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s00134-020-06009-2

    authors: Arabi YM,Murthy S,Webb S

    更新日期:2020-05-01 00:00:00

  • Morphologic characteristics of central pulmonary thromboemboli predict haemodynamic response in massive pulmonary embolism.

    abstract:OBJECTIVE:On hospital admission, the morphology of the central pulmonary artery thromboemboli is an independent predictor of 30-day mortality in patients with massive pulmonary embolism (MPE). This may be due to the differential susceptibility of thromboemboli to thrombolysis. The aim of this study was to assess haemod...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-004-2314-5

    authors: Podbregar M,Voga G,Krivec B

    更新日期:2004-08-01 00:00:00

  • Sedation practice and discomfort during withdrawal of mechanical ventilation in critically ill patients at end-of-life: a post-hoc analysis of a multicenter study.

    abstract:PURPOSE:Little is known on the incidence of discomfort during the end-of-life of intensive care unit (ICU) patients and the impact of sedation on such discomfort. The aim of this study was to assess the incidence of discomfort events according to levels of sedation. METHODS:Post-hoc analysis of an observational prospe...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-020-05930-w

    authors: Robert R,Le Gouge A,Kentish-Barnes N,Adda M,Audibert J,Barbier F,Bourcier S,Bourenne J,Boyer A,Devaquet J,Grillet G,Guisset O,Hyacinthe AC,Jourdain M,Lerolle N,Lesieur O,Mercier E,Messika J,Renault A,Vinatier I,Az

    更新日期:2020-06-01 00:00:00

  • Muscle perfusion and oxygen consumption by near-infrared spectroscopy in septic-shock and non-septic-shock patients.

    abstract:OBJECTIVE:To measure muscle blood flow (Qtis) and oxygen consumption (VO(2)tis) in septic and non-septic critically ill patients by near-infrared spectroscopy (NIRS). SETTING:Surgical intensive care unit of a university hospital. PATIENTS AND PARTICIPANTS:Four patients with septic shock, eight post-surgical criticall...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-003-1805-0

    authors: Girardis M,Rinaldi L,Busani S,Flore I,Mauro S,Pasetto A

    更新日期:2003-07-01 00:00:00

  • Hepatic mitochondrial redox state in hypotensive brain-dead patients and an effect of dopamine administration.

    abstract::Arterial blood ketone body ratio, reflecting hepatic mitochondrial redox state, was measured in 26 brain-dead patients who were hypotensive but hemodynamically stable. All of them had substantially normal hepatic function. In 18 of the patients, blood ketone body ratio was maintained within the normal range in spite o...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF01691432

    authors: Nakatani T,Ishikawa Y,Kobayashi K,Ozawa K

    更新日期:1991-01-01 00:00:00

  • High-mobility group box 1 protein plasma concentrations during septic shock.

    abstract:OBJECTIVE:To investigate plasma high-mobility group box 1 protein (HMGB1) concentration and its relationship with organ dysfunction and outcome in septic shock patients. DESIGN AND SETTING:Prospective, noninterventional study. Medical adult intensive care unit at a university hospital in France. PATIENTS:42 criticall...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-007-0691-2

    authors: Gibot S,Massin F,Cravoisy A,Barraud D,Nace L,Levy B,Bollaert PE

    更新日期:2007-08-01 00:00:00

  • Luxatio cordis due to right pericardium tear, a difficult diagnosis: report of a case.

    abstract:BACKGROUND:Dislocation of the heart is a rare complication of thoracic blunt trauma. A high index of suspicion of pericardium rupture is necessary to formulate an early diagnosis to reduce morbidity and mortality. PATIENTS:A 23-year-old man suffered a blunt thoracoabdominal trauma and was admitted 3 days later to a un...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-002-1328-0

    authors: Piazza O,De Robertis E,Fraioli G,Tufano R

    更新日期:2002-07-01 00:00:00

  • Hemodynamic and gas exchange responses to inhalation of nitric oxide in patients with the acute respiratory distress syndrome and in hypoxemic patients with chronic obstructive pulmonary disease.

    abstract:OBJECTIVE:Inhalation of nitric oxide (NO) can improve oxygenation and decrease mean pulmonary artery pressure (MPAP) in patients with the acute respiratory distress syndrome (ARDS). It is not known whether inhaled NO exerts a similar effect in hypoxemic patients with chronic obstructive pulmonary disease (COPD). DESIG...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340050290

    authors: Blanch L,Joseph D,Fernández R,Mas A,Martinez M,Vallés J,Diaz E,Baigorri F,Artigas A

    更新日期:1997-01-01 00:00:00

  • Torsade de pointes as a complication of brainstem encephalitis.

    abstract::A case of brainstem encephalitis complicated by torsade de pointes is described. The possible occurrence of ventricular arrhythmias may contribute to the mortality in this condition. We recommend the admission of patients with brainstem encephalitis to an intensive care unit, for a period of electrocardiographic monit...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF00263564

    authors: De Keyser J,De Boel S,Ceulemans L,Ebinger G

    更新日期:1987-01-01 00:00:00

  • Lipid peroxidation and alpha-tocopherol during an acute respiratory failure after near drowning.

    abstract::We compare two patients admitted after near drowning. Both presented a severe metabolic acidosis, but only one of them developed an acute pulmonary edema with hypoxemia. An increase of lipid peroxides associated with a reduction of vitamin E concentration has been observed in this later patient. Lipid peroxidation, on...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF00254776

    authors: Bertrand Y,Artoisenet A,Allard B,Barbier B,de Meulder A,Raynaert M,Mathieu P,Dumont E

    更新日期:1985-01-01 00:00:00

  • Relation of echocardiographic preload indices to stroke volume in critically ill patients with normal and low cardiac index.

    abstract:OBJECTIVE:To examine the usefulness of preload indices obtained by transoesophageal echocardiography (TOE) for estimating stroke volume at various levels of cardiac index. DESIGN:Prospective clinical study. SETTING:Intensive care unit with surgical patients. PATIENTS:16 ventilated patients monitored via Swan-Ganz ca...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340050349

    authors: Greim CA,Roewer N,Apfel C,Laux G,Schulte am Esch J

    更新日期:1997-04-01 00:00:00

  • Respiratory variations in the arterial pressure during mechanical ventilation reflect volume status and fluid responsiveness.

    abstract::Optimal fluid management is one of the main challenges in the care of the critically ill. However, the physiological parameters that are commonly monitored and used to guide fluid management are often inadequate and even misleading. From 1987 to 1989 we published four experimental studies which described a method for ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-014-3285-9

    authors: Perel A,Pizov R,Cotev S

    更新日期:2014-06-01 00:00:00

  • ICU-acquired candidemia within selective digestive decontamination studies: a meta-analysis.

    abstract:PURPOSE:To estimate the direct and indirect (contextual) effects of the factorized constituents of selective digestive decontamination and selective oropharyngeal decontamination (SDD/SOD), being topical antibiotic (TA) and protocolized antifungal prophylaxis (PAFP), on ICU-acquired candidemia. METHODS:A broad range o...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,meta分析

    doi:10.1007/s00134-015-4004-x

    authors: Hurley JC

    更新日期:2015-11-01 00:00:00

  • Erythromycin versus metoclopramide for post-pyloric spiral nasoenteric tube placement: a randomized non-inferiority trial.

    abstract:PURPOSE:To determine whether erythromycin is non-inferior to metoclopramide in facilitating post-pyloric placement of self-propelled spiral nasoenteric tubes (NETs) in critically ill patients. METHODS:A prospective, multicenter, open-label, parallel, and non-inferiority randomized controlled trial was conducted compar...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s00134-018-5466-4

    authors: Hu B,Ouyang X,Lei L,Sun C,Chi R,Guo J,Guo W,Zhang Y,Li Y,Huang D,Sun H,Nie Z,Yu J,Zhou Y,Wang H,Zhang J,Chen C

    更新日期:2018-12-01 00:00:00

  • Variability of splanchnic blood flow in patients with sepsis.

    abstract:OBJECTIVES:Previous studies on therapeutic interventions in sepsis have assumed stability of the measure of splanchnic blood flow throughout the study. We assessed the variability of splanchnic blood flow during stable global hemodynamics in eight patients with sepsis requiring treatment with dobutamine and/or norepine...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340100980

    authors: Sakka SG,Reinhart K,Wegscheider K,Meier-Hellmann A

    更新日期:2001-08-01 00:00:00

  • The endothelium: physiological functions and role in microcirculatory failure during severe sepsis.

    abstract::The endothelium is a highly dynamic cell layer that is involved in a multitude of physiological functions, including the control of vascular tone, the movement of cells and nutrients, the maintenance of blood fluidity and the growth of new vessels. During severe sepsis, the endothelium becomes proadhesive, procoagulan...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-010-1893-6

    authors: Ait-Oufella H,Maury E,Lehoux S,Guidet B,Offenstadt G

    更新日期:2010-08-01 00:00:00

  • Effects of bystander first aid, defibrillation and advanced life support on neurologic outcome and hospital costs in patients after ventricular fibrillation cardiac arrest.

    abstract:OBJECTIVE:To evaluate the effects of basic life support, time to first defibrillation and emergency medical service arrival time on neurologic outcome and expenses for hospital care in patients after cardiac arrest. SETTING:Large urban emergency medical services system and emergency department in a 2000-bed university...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340101045

    authors: Bur A,Kittler H,Sterz F,Holzer M,Eisenburger P,Oschatz E,Kofler J,Laggner AN

    更新日期:2001-09-01 00:00:00

  • Clinical estimation of trunk position among mechanically ventilated patients.

    abstract:OBJECTIVES:Trunk position at 45 degrees from the horizontal is associated with a decreased risk of gastroesophageal aspiration. The objectives of this study were to determine the accuracy of trunk flexion estimates compared to a reference standard measurement, and to determine agreement about trunk flexion among ICU cl...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-002-1225-6

    authors: McMullin JP,Cook DJ,Meade MO,Weaver BR,Letelier LM,Kahmamoui K,Higgins DA,Guyatt GH

    更新日期:2002-03-01 00:00:00

  • Milrinone, dobutamine or epinephrine use in asphyxiated newborn pigs resuscitated with 100% oxygen.

    abstract:BACKGROUND:After resuscitation, asphyxiated neonates often develop poor cardiac function with hypotension, pulmonary hypertension and multiorgan ischemia. In a swine model of neonatal hypoxia-reoxygenation, effects of epinephrine, dobutamine and milrinone on systemic, pulmonary and regional hemodynamics and oxygen tran...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-010-1820-x

    authors: Joynt C,Bigam DL,Charrois G,Jewell LD,Korbutt G,Cheung PY

    更新日期:2010-06-01 00:00:00

  • Will your patient benefit from palliative care? A multicenter exploratory survey about the acceptance of trigger factors for palliative care consultations among ICU physicians.

    abstract:: ...

    journal_title:Intensive care medicine

    pub_type: 评论,信件

    doi:10.1007/s00134-018-5461-9

    authors: Adler K,Schlieper D,Kindgen-Milles D,Meier S,Schallenburger M,Sellmann T,Schwager H,Schwartz J,Neukirchen M

    更新日期:2019-01-01 00:00:00

  • Intracranial hypertension in head injury: management and results.

    abstract:OBJECTIVE:(1) To describe the pattern of intracranial pressure (ICP) and cerebral perfusion pressure (CPP) in a group of severe head-injured patients, (2) to quantify complications of ICP monitoring, and (3) to describe a management protocol and its results. DESIGN:Prospective observational study. SETTING:General int...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340050860

    authors: Stocchetti N,Rossi S,Buzzi F,Mattioli C,Paparella A,Colombo A

    更新日期:1999-04-01 00:00:00

  • Base deficit in immediate postoperative period of coronary surgery with cardiopulmonary bypass and length of stay in intensive care unit.

    abstract:OBJECTIVE:To assess the relationship between the base deficit value in the immediate postoperative period of coronary surgery for cardiopulmonary bypass and the length of stay in the ICU. DESIGN AND SETTING:Prospective descriptive study in the department of anesthesia and cardiovascular surgery of a university hospita...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-002-1587-9

    authors: Hugot P,Sicsic JC,Schaffuser A,Sellin M,Corbineau H,Chaperon J,Ecoffey C

    更新日期:2003-02-01 00:00:00

  • Reliability in diagnosis of brain death.

    abstract:OBJECTIVE:To compare some of the confirmatory investigations of brain death with clinical criteria in order to achieve the most sensitive and accurate diagnosis of brain death. DESIGN:All patients with isolated brain lesions and Glasgow Coma Scale (GCS) = 3 were subjected to neurological examination after ruling out h...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF01711544

    authors: Paolin A,Manuali A,Di Paola F,Boccaletto F,Caputo P,Zanata R,Bardin GP,Simini G

    更新日期:1995-08-01 00:00:00

  • Suctioning through a double-lumen endotracheal tube helps to prevent alveolar collapse and to preserve ventilation.

    abstract:OBJECTIVE:Endotracheal suctioning can cause alveolar collapse and impede ventilation. One reason is the gas flow through a single-lumen endotracheal tube (ETT) provoking a gradient between airway opening and tracheal (P(tr)) pressures. Separately extending the patient tubing limbs of a suitable ventilator into the trac...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-004-2537-5

    authors: Reissmann H,Böhm SH,Suárez-Sipmann F,Tusman G,Buschmann C,Maisch S,Pesch T,Thamm O,Plümers C,Schulte am Esch J,Hedenstierna G

    更新日期:2005-03-01 00:00:00

  • Helmet CPAP vs. oxygen therapy in severe hypoxemic respiratory failure due to pneumonia.

    abstract:PURPOSE:The efficacy of noninvasive continuous positive airway pressure (CPAP) to improve outcomes in severe hypoxemic acute respiratory failure (hARF) due to pneumonia has not been clearly established. The aim of this study was to compare CPAP vs. oxygen therapy to reduce the risk of meeting criteria for endotracheal ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s00134-014-3325-5

    authors: Brambilla AM,Aliberti S,Prina E,Nicoli F,Del Forno M,Nava S,Ferrari G,Corradi F,Pelosi P,Bignamini A,Tarsia P,Cosentini R

    更新日期:2014-07-01 00:00:00

  • Profound and persistent decrease of circulating dendritic cells is associated with ICU-acquired infection in patients with septic shock.

    abstract:PURPOSE:Septic shock induces a decrease in dendritic cells (DCs) that may contribute to sepsis-induced immunosuppression. We analyzed the time course of circulating DCs in patients with septic shock and its relation to susceptibility to intensive care unit (ICU)-acquired infections. METHODS:We enrolled adult patients ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-011-2306-1

    authors: Grimaldi D,Louis S,Pène F,Sirgo G,Rousseau C,Claessens YE,Vimeux L,Cariou A,Mira JP,Hosmalin A,Chiche JD

    更新日期:2011-09-01 00:00:00