Suctioning through a double-lumen endotracheal tube helps to prevent alveolar collapse and to preserve ventilation.

Abstract:

OBJECTIVE:Endotracheal suctioning can cause alveolar collapse and impede ventilation. One reason is the gas flow through a single-lumen endotracheal tube (ETT) provoking a gradient between airway opening and tracheal (P(tr)) pressures. Separately extending the patient tubing limbs of a suitable ventilator into the trachea via a double-lumen ETT should maintain P(tr). Can this technique reduce the side effects? DESIGN AND SETTING:Bench and animal studies in a university hospital laboratory. INTERVENTIONS:A lung model was ventilated via single and double-lumen ETTs. Closed-system suctioning was applied with catheters introduced into the single-lumen ETT or the expiratory lumen of the double-lumen ETT via swivel adapter. Seven anesthetized pigs (lungs lavaged) underwent three runs of ventilation and suctioning through (a, b) an 8.0-mm ID single-lumen ETT, (c) a double-lumen ETT (41Ch outer diameter, OD). In (a) the single-lumen ETT was disconnected for suctioning, in (b) and (c) ventilator mode was set to continuous positive airway pressure mode, and the ETTs remained connected. MEASUREMENTS AND RESULTS:Bench: Suction through single-lumen ETTs impaired ventilation and led to strongly negative P(tr) (common: -10 to -20 mbar); the double-lumen ETT technique maintained ventilation and pressures. ANIMALS:Lung gas content (computed tomography, n=4) and arterial oxygen partial pressure, initially 1462+/-65 ml/532+/-76 mmHg, were significantly reduced by suctioning through single-lumen ETT: to 302+/-79 ml/62+/-6 mmHg with disconnection and to 851+/-211 ml/158+/-107 mmHg with closed suction. With double-lumen ETT they remained at 1377+/-95 ml/521+/-56 mmHg. CONCLUSIONS:The double-lumen ETT technique minimizes side effects of suctioning by maintaining P(tr).

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Reissmann H,Böhm SH,Suárez-Sipmann F,Tusman G,Buschmann C,Maisch S,Pesch T,Thamm O,Plümers C,Schulte am Esch J,Hedenstierna G

doi

10.1007/s00134-004-2537-5

keywords:

subject

Has Abstract

pub_date

2005-03-01 00:00:00

pages

431-40

issue

3

eissn

0342-4642

issn

1432-1238

journal_volume

31

pub_type

杂志文章
  • Interventions to reduce medication prescribing errors in a paediatric cardiac intensive care unit.

    abstract:OBJECTIVE:To identify and reduce medication-prescribing errors by introducing systematic physician education and post-cardiac surgery admission prescription forms. DESIGN:Errors were defined as: incomplete prescriptions; potential adverse drug events (ADEs), i.e. either intercepted or non-intercepted incorrect prescri...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-008-1054-3

    authors: Burmester MK,Dionne R,Thiagarajan RR,Laussen PC

    更新日期:2008-06-01 00:00:00

  • Pressure-volume curves with and without muscle paralysis in acute respiratory distress syndrome.

    abstract:OBJECTIVE:Pressure-volume (PV) curves are recorded after induction of complete muscle paralysis, which may limit their clinical use. The feasibility of recording PV curves without paralysis has not been tested. In 19 patients with acute respiratory distress syndrome (ARDS) and no hemodynamic instability we prospectivel...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00134-006-0265-8

    authors: Decailliot F,Demoule A,Maggiore SM,Jonson B,Duvaldestin P,Brochard L

    更新日期:2006-09-01 00:00:00

  • Base deficit in immediate postoperative period of coronary surgery with cardiopulmonary bypass and length of stay in intensive care unit.

    abstract:OBJECTIVE:To assess the relationship between the base deficit value in the immediate postoperative period of coronary surgery for cardiopulmonary bypass and the length of stay in the ICU. DESIGN AND SETTING:Prospective descriptive study in the department of anesthesia and cardiovascular surgery of a university hospita...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-002-1587-9

    authors: Hugot P,Sicsic JC,Schaffuser A,Sellin M,Corbineau H,Chaperon J,Ecoffey C

    更新日期:2003-02-01 00:00:00

  • Optimisation of positive end-expiratory pressure by forced oscillation technique in a lavage model of acute lung injury.

    abstract:PURPOSE:We evaluated whether oscillatory compliance (C(X5)) measured by forced oscillation technique (FOT) at 5 Hz may be useful for positive end-expiratory pressure (PEEP) optimisation. METHODS:We studied seven pigs in which lung injury was induced by broncho-alveolar lavage. The animals were ventilated in volume con...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-011-2211-7

    authors: Dellacà RL,Zannin E,Kostic P,Olerud MA,Pompilio PP,Hedenstierna G,Pedotti A,Frykholm P

    更新日期:2011-06-01 00:00:00

  • Inhibition of human neutrophil chemotaxis toward interleukin 8 with six clinical antithrombin concentrates in vitro.

    abstract:OBJECTIVE:Antithrombin exerts direct effects on neutrophils by inhibiting chemokine-induced migration. This study examined the potency of different pharmaceutical antithrombin preparations in inhibiting neutrophil chemotaxis toward interleukin 8. METHODS:Cell migration was tested by the leading front assay in modified...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-002-1432-1

    authors: Kaneider NC,Rabensteiner A,Reinisch CM,Dunzendorfer S,Wiedermann CJ

    更新日期:2002-10-01 00:00:00

  • The ten pitfalls of lactate clearance in sepsis.

    abstract:: ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-018-5213-x

    authors: Hernandez G,Bellomo R,Bakker J

    更新日期:2019-01-01 00:00:00

  • Inter-observer variability in APACHE II scoring: effect of strict guidelines and training.

    abstract:OBJECTIVE:To assess the effect of strict guidelines and a rigorous training program on variability in scoring the revised Acute Physiology and Chronic Health Evaluation (APACHE II). DESIGN AND SETTING:Prospective survey and intervention in the surgical ICU of a university teaching hospital. MEASUREMENTS:Seven experie...

    journal_title:Intensive care medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/s001340101012

    authors: Polderman KH,Jorna EM,Girbes AR

    更新日期:2001-08-01 00:00:00

  • Critical illness onychomadesis.

    abstract:OBJECTIVE:To present our observation of the development of a rare nail deformity in the prolonged course of disease of a critically ill patient with a pulmonary abscess. DESIGN:Case report. SETTING:Tertiary referral, 16-bed, level I surgical ICU in an academic hospital. PATIENT:A 48-year-old Caucasian male was treat...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340000679

    authors: Wester JP,van Eps RS,Stouthamer A,Girbes AR

    更新日期:2000-11-01 00:00:00

  • Time course of lung injury in rat acute pancreatitis.

    abstract:OBJECTIVE:Lung injury is a severe complication of acute pancreatitis that increases the mortality rate of the disease. The pathophysiology of acute pancreatitis has been studied in several experimental models, but the kinetics of pulmonary complications in relation to the pancreatic disease is not completely understood...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-006-0264-9

    authors: Morel DR,Frossard JL,Cikirikcioglu B,Tapponnier M,Pastor CM

    更新日期:2006-11-01 00:00:00

  • Effects of blood glucose transcription mismatches on a computer-based intensive insulin therapy protocol.

    abstract:PURPOSE:Computerized clinical decision support systems (CDSS) for intensive insulin therapy (IIT) generate recommendations using blood glucose (BG) values manually transcribed from testing devices to computers, a potential source of error. We quantified the frequency and effect of blood glucose transcription mismatches...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-010-1868-7

    authors: Campion TR Jr,May AK,Waitman LR,Ozdas A,Gadd CS

    更新日期:2010-09-01 00:00:00

  • Middle cerebral artery flow velocity decreases and electroencephalogram (EEG) changes occur as acute hypercapnia reverses.

    abstract:OBJECTIVE:To define the changes in middle cerebral artery flow velocity (Vmca) and the electroencephalogram (EEG) during rapid reduction in arterial carbon dioxide (PCO2) from acute hypercapnia. DESIGN. Human volunteer study. SETTING:University-affiliated hospital experimental laboratory. PARTICIPANTS:Nine healthy vo...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-003-1917-6

    authors: Halpern P,Neufeld MY,Sade K,Silbiger A,Szold O,Bornstein NM,Sorkine P

    更新日期:2003-10-01 00:00:00

  • Bilateral pseudoaneurysms of the pulmonary arteries caused by blunt chest injury.

    abstract::A case of bilateral pseudoaneurysms of the pulmonary arteries caused by blunt chest injury is presented. Although this is a very rare complication, this entity should always be suspected in a patient with hemoptysis and a radiodensity on chest radiograph following chest injury. Selection of operative procedures should...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/BF01706428

    authors: Kasai T,Kobayashi K

    更新日期:1992-01-01 00:00:00

  • Diagnostic accuracy of Doppler renal resistive index for reversibility of acute kidney injury in critically ill patients.

    abstract:OBJECTIVES:Diagnosing persistent acute kidney injury (AKI) as opposed to transient AKI in critically ill patients may help physicians in making treatment decisions. This diagnosis relies chiefly on urinary indices, which may be of limited value or difficult to obtain. We assessed the performance of the Doppler renal re...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-010-2050-y

    authors: Darmon M,Schortgen F,Vargas F,Liazydi A,Schlemmer B,Brun-Buisson C,Brochard L

    更新日期:2011-01-01 00:00:00

  • Evaluation of two processed EEG analyzers for assessment of sedation after coronary artery bypass grafting.

    abstract:OBJECTIVES:Processed EEG monitoring has been suggested for sedation depth evaluation in intensive care unit (ICU) patients. The present study investigated the efficacy of two processed EEG monitors using SEF90% or SEF95% and BIS to differentiate between conscious (Ramsay score 4) and unconscious sedation (Ramsay score ...

    journal_title:Intensive care medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s001340000761

    authors: Walder B,Suter PM,Romand JA

    更新日期:2001-01-01 00:00:00

  • Assessment of clinical risk predictive rules for invasive candidiasis in a prospective multicentre cohort of ICU patients.

    abstract:PURPOSE:To assess the generalisability of published clinical risk predictive models for invasive candidiasis in ICU patients. METHODS:The performance characteristics of published clinical risk factor-only and Candida colonisation-only predictive models for invasive candidiasis were assessed in a multicentre cohort of ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00134-009-1619-9

    authors: Playford EG,Lipman J,Kabir M,McBryde ES,Nimmo GR,Lau A,Sorrell TC

    更新日期:2009-12-01 00:00:00

  • Automating the weaning process with advanced closed-loop systems.

    abstract:BACKGROUND:Limiting the duration of invasive ventilation is an important goal in caring for critically ill patients. Several clinical trials have shown that compared to traditional care, protocols can reduce the total duration of mechanical ventilation. Computerized or automated weaning has the potential to improve wea...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-008-1154-0

    authors: Burns KE,Lellouche F,Lessard MR

    更新日期:2008-10-01 00:00:00

  • Multinational development and validation of an early prediction model for delirium in ICU patients.

    abstract:RATIONALE:Delirium incidence in intensive care unit (ICU) patients is high and associated with poor outcome. Identification of high-risk patients may facilitate its prevention. PURPOSE:To develop and validate a model based on data available at ICU admission to predict delirium development during a patient's complete I...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00134-015-3777-2

    authors: Wassenaar A,van den Boogaard M,van Achterberg T,Slooter AJ,Kuiper MA,Hoogendoorn ME,Simons KS,Maseda E,Pinto N,Jones C,Luetz A,Schandl A,Verbrugghe W,Aitken LM,van Haren FM,Donders AR,Schoonhoven L,Pickkers P

    更新日期:2015-06-01 00:00:00

  • Metabolic arrest.

    abstract::In hypoxia sensitive cells and tissues, the rates of glucose and O2 consumption are inversely related (Pasteur Effect). Under O2 limiting conditions the demands for glucose (glycogen) in such cells may drastically rise as a means for maintaining ATP turnover close to normoxic rates; nevertheless ion and electrical pot...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF00254926

    authors: Hochachka PW

    更新日期:1986-01-01 00:00:00

  • Abdominal compartment syndrome and intrahepatic portal venous gas: a possible complication of endoscopy.

    abstract:OBJECTIVE:We report the first patient to developed abdominal compartment syndrome (ACS) with intrahepatic portal venous gas (IHPVG) and pneumatosis cystoides intestinalis following emergency upper gastrointestinal endoscopy. CASE PRESENTATION:A 53-year-old man underwent an emergency upper gastrointestinal endoscopy fo...

    journal_title:Intensive care medicine

    pub_type: 信件

    doi:10.1007/s00134-002-1492-2

    authors: Hayakawa M,Gando S,Kameue T,Morimoto Y,Kemmotsu O

    更新日期:2002-11-01 00:00:00

  • ICU-acquired candidemia within selective digestive decontamination studies: a meta-analysis.

    abstract:PURPOSE:To estimate the direct and indirect (contextual) effects of the factorized constituents of selective digestive decontamination and selective oropharyngeal decontamination (SDD/SOD), being topical antibiotic (TA) and protocolized antifungal prophylaxis (PAFP), on ICU-acquired candidemia. METHODS:A broad range o...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,meta分析

    doi:10.1007/s00134-015-4004-x

    authors: Hurley JC

    更新日期:2015-11-01 00:00:00

  • Infant lung function testing in the intensive care unit.

    abstract::As a result of the previous shortage of tools to assess objectively the overall physiological status of the respiratory system in infants and young children, it has been difficult to measure the degree of physiological disorder or the response to therapy in respiratory diseases such as BPD, the pediatric version of AR...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/BF01704742

    authors: Hammer J,Newth CJ

    更新日期:1995-09-01 00:00:00

  • Comparison of electrocardiograms recorded with standard leads and derived from the vectorcardiographic frank leads in high risk patients.

    abstract::Dynamic vectorcardiography (VCG) is increasingly employed for ischaemia monitoring with the use of a computerized method for recording and on-line analysis by the calculation of trend parameters. To elucidate how well the derived electrocardiogram (dECG), calculated from the VCG, compares with the simultaneously regis...

    journal_title:Intensive care medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/s001340050455

    authors: Gannedahl PE,Ljungqvist OH,Lundin P,Edner M

    更新日期:1997-10-01 00:00:00

  • Bench studies evaluating devices for non-invasive ventilation: critical analysis and future perspectives.

    abstract:PURPOSE:Because non-invasive mechanical ventilation (NIV) is increasingly used, new devices, both ventilators and interfaces, have been continuously proposed for clinical use in recent years. To provide the clinicians with valuable information about ventilators and interfaces for NIV, several bench studies evaluating a...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-011-2416-9

    authors: Olivieri C,Costa R,Conti G,Navalesi P

    更新日期:2012-01-01 00:00:00

  • Serum procalcitonin measurement contribution to the early diagnosis of candidemia in critically ill patients.

    abstract:BACKGROUND:Candidemia is a life-threatening infection in the ICU whose prognosis is highly dependent on the stage at which it is recognized. Procalcitonin (PCT) levels have been shown to accurately distinguish between bacteremia and noninfectious inflammatory states in critically ill patients with clinical signs of sep...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-006-0306-3

    authors: Charles PE,Dalle F,Aho S,Quenot JP,Doise JM,Aube H,Olsson NO,Blettery B

    更新日期:2006-10-01 00:00:00

  • Conflicts of interest disclosure forms and management in critical care clinical practice guidelines.

    abstract:BACKGROUND:Trustworthy clinical practice guidelines (CPGs) require identification and careful management of conflicts of interest (COIs) among all participants in the guideline development. Furthermore, COIs are more common than anticipated. However, there are no universally accepted methods to identify and manage COIs...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-018-5367-6

    authors: Alhazzani W,Lewis K,Jaeschke R,Rochwerg B,Møller MH,Evans L,Wilson KC,Patel S,Coopersmith CM,Cecconi M,Guyatt G,Akl EA

    更新日期:2018-10-01 00:00:00

  • Regional distribution of gas and tissue in acute respiratory distress syndrome. II. Physiological correlations and definition of an ARDS Severity Score. CT Scan ARDS Study Group.

    abstract:OBJECTIVES:(a) To assess whether differences in lung morphology observed in patients with adult respiratory distress syndrome (ARDS) are associated with differences in cardiorespiratory parameters, lung mechanics, and outcome. (b) To propose a new ARDS Severity Score to identify patients with a high mortality risk. DE...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340051317

    authors: Rouby JJ,Puybasset L,Cluzel P,Richecoeur J,Lu Q,Grenier P

    更新日期:2000-08-01 00:00:00

  • The influence of infection sites on development and mortality of ARDS.

    abstract:OBJECTIVE:Infection is the most frequent cause of acute respiratory distress syndrome (ARDS). However, little is known about the influence of infection sites on ARDS. This study aimed to assess the associations of infection sites with ARDS development and mortality in critically ill infected patients. DESIGN:Prospecti...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-010-1851-3

    authors: Sheu CC,Gong MN,Zhai R,Bajwa EK,Chen F,Thompson BT,Christiani DC

    更新日期:2010-06-01 00:00:00

  • Early tracheotomy versus prolonged endotracheal intubation in unselected severely ill ICU patients.

    abstract:OBJECTIVE:Although several advantages are attributed to tracheotomy in ICU patients requiring mechanical ventilation (MV), true benefits and the optimal timing of tracheotomy remain controversial. In this study, we compared early tracheotomy (ET) with prolonged intubation (PI) in severely ill patients requiring prolong...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s00134-008-1195-4

    authors: Blot F,Similowski T,Trouillet JL,Chardon P,Korach JM,Costa MA,Journois D,Thiéry G,Fartoukh M,Pipien I,Bruder N,Orlikowski D,Tankere F,Durand-Zaleski I,Auboyer C,Nitenberg G,Holzapfel L,Tenaillon A,Chastre J,Laplanch

    更新日期:2008-10-01 00:00:00

  • The endothelium: physiological functions and role in microcirculatory failure during severe sepsis.

    abstract::The endothelium is a highly dynamic cell layer that is involved in a multitude of physiological functions, including the control of vascular tone, the movement of cells and nutrients, the maintenance of blood fluidity and the growth of new vessels. During severe sepsis, the endothelium becomes proadhesive, procoagulan...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-010-1893-6

    authors: Ait-Oufella H,Maury E,Lehoux S,Guidet B,Offenstadt G

    更新日期:2010-08-01 00:00:00

  • Isoflurane for prolonged sedation in the intensive care unit; efficacy and safety.

    abstract:OBJECTIVE:To compare isoflurane with midazolam for prolonged sedation in ventilated patients. DESIGN:Randomised controlled study. SETTING:General intensive care unit in university teaching hospital. PATIENTS:Sixty patients aged 17-80 years who required mechanical ventilation for more than 24 h. INTERVENTIONS:Sedati...

    journal_title:Intensive care medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF01694344

    authors: Spencer EM,Willatts SM

    更新日期:1992-01-01 00:00:00