Metabolic arrest.

abstract：OBJECTIVE:Alterations in coagulation, including elevated pulmonary and systemic concentrations of urokinase, are frequent in patients with acute lung injury (ALI). Urokinase potentiates neutrophil activation and contributes to the severity of pulmonary injury in preclinical models of ALI. The objective of this study wa...

journal_title：Intensive care medicine

authors： Arcaroli J,Sankoff J,Liu N,Allison DB,Maloney J,Abraham E

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:To compare the effects of a cerebral perfusion pressure (CPP) intervention achieved with dopamine and norepinephrine after severe head injury. DESIGN:Prospective, controlled, trial. SETTING:Neurosciences critical care unit. PATIENTS:Eleven patients with a head injury, requiring dopamine or norepinephrine i...

journal_title：Intensive care medicine

authors： Johnston AJ,Steiner LA,Chatfield DA,Coles JP,Hutchinson PJ,Al-Rawi PG,Menon DK,Gupta AK

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:To assess the impact of hemodynamic variables on the outcome of critically ill patients in septic shock and to identify the optimal threshold values related to outcome with special reference to continuously monitored mean arterial pressure (MAP) and mixed venous oxygen saturation (SvO2). DESIGN AND SETTING:R...

journal_title：Intensive care medicine

authors： Varpula M,Tallgren M,Saukkonen K,Voipio-Pulkki LM,Pettilä V

更新日期：2005-08-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of intravenous sildenafil for immediate postoperative pulmonary hypertension (PH) in pediatric patients undergoing congenital heart surgery. METHODS:A double-blind, multicenter, placebo-controlled, dose-ranging, parallel-group trial was conducted. Patients were randomized to...

journal_title：Intensive care medicine

authors： Fraisse A,Butrous G,Taylor MB,Oakes M,Dilleen M,Wessel DL

更新日期：2011-03-01 00:00:00

abstract：:Nosocomial pneumonia continues to represent a significant cause of morbidity and mortality in hospitalized patients. Bacteria are responsible for greater than 90% of the pneumonias, the most common isolates being aerobic Gram-negative bacilli and S. aureus. Cornerstones of treatment are intravenous antibiotics and sup...

journal_title：Intensive care medicine

authors： Unertl KE,Lenhart FP,Forst H,Peter K

更新日期：1992-01-01 00:00:00

abstract：:We analysed the case histories of 22 patients with life threatening asthma retrospectively. Fifteen patients needed mechanical ventilation. Three patients, all of them in cardiac arrest before or at the moment of admission, died. In five patients, halothane therapy was successfully used as a last resort. No major comp...

journal_title：Intensive care medicine

authors： Rosseel P,Lauwers LF,Baute L

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between cytokines and the inflammatory responses in patients with out-of-hospital cardiac arrest, we examined the changes of cytokines as well as alterations in the markers of neutrophil activation, platelet and endothelial activation, and endothelial injury. DESIGN:Prospectiv...

journal_title：Intensive care medicine

authors： Gando S,Nanzaki S,Morimoto Y,Kobayashi S,Kemmotsu O

更新日期：1999-06-01 00:00:00

abstract：:Dynamic vectorcardiography (VCG) is increasingly employed for ischaemia monitoring with the use of a computerized method for recording and on-line analysis by the calculation of trend parameters. To elucidate how well the derived electrocardiogram (dECG), calculated from the VCG, compares with the simultaneously regis...

journal_title：Intensive care medicine

authors： Gannedahl PE,Ljungqvist OH,Lundin P,Edner M

更新日期：1997-10-01 00:00:00

abstract：:Total extracorporeal lung assist (ECLA) requires a bypass flow approaching cardiac output. Recirculation of venous blood through the oxygenator is minimized with a veno-right ventricular cannulation technique which separates venous drainage from returned oxygenated blood. A case of posttraumatic ARDS was treated with ...

journal_title：Intensive care medicine

authors： Wetterberg T,Steen S

更新日期：1991-01-01 00:00:00

abstract：:Physicians are increasingly involved in how their critically ill patients die [72]. The more this happens, the more physicians will have to understand not only how their own backgrounds and biases influence their medical management, but also the cultural and religious backgrounds of the patient and surrogate [72, 73]....

journal_title：Intensive care medicine

authors： Nyman DJ,Sprung CL

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVE:This study compared the recently introduced Microcuff endotracheal tube HVLP ICU featuring an ultrathin (7-microm) polyurethane cuff membrane with endotracheal tubes from different manufacturers regarding fluid leakage past the tube cuff. DESIGN:In vitro setup. MEASUREMENTS AND RESULTS:The following endotra...

journal_title：Intensive care medicine

authors： Dullenkopf A,Gerber A,Weiss M

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of some acid-base abnormalities on blood capacity of transporting CO(2). DESIGN:Prospective study. SETTING:General and Cardiosurgical ICUs of a University hospital. PATIENTS:Six groups of ten patients characterized by: metabolic alkalosis; respiratory alkalosis; absence of acid-b...

journal_title：Intensive care medicine

authors： Cavaliere F,Antonelli M,Arcangeli A,Conti G,Pennisi MA,Proietti R

更新日期：2002-05-01 00:00:00

abstract：:Acute renal failure in critically ill patients is seldom an isolated problem but is more usually associated with multiple organ failure. When choosing an extracorporeal kidney replacement therapy, these other failing organs must be taken into account. Therefore the choice of an artificial kidney in patients requiring ...

journal_title：Intensive care medicine

authors： Schetz M,Lauwers PM,Ferdinande P

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:Ventricular-arterial (V-A) decoupling decreases myocardial efficiency and is exacerbated by tachycardia that increases static arterial elastance (Ea). We thus investigated the effects of heart rate (HR) reduction on Ea in septic shock patients using the beta-blocker esmolol. We hypothesized that esmolol improve...

journal_title：Intensive care medicine

authors： Morelli A,Singer M,Ranieri VM,D'Egidio A,Mascia L,Orecchioni A,Piscioneri F,Guarracino F,Greco E,Peruzzi M,Biondi-Zoccai G,Frati G,Romano SM

更新日期：2016-10-01 00:00:00

abstract：:A randomized study of 30 patients undergoing uncomplicated surgery under spinal anesthesia was conducted to assess the influence of colloids on the kinetics of plasma fibronectin and complement. Both are opsonins of the reticuloendothelial system; moreover fibronectin is concerned with host resistance against septic c...

journal_title：Intensive care medicine

authors： Vedrinne JM,Hoen JP,Bussery D,Veyssere C,Richard M,Motin J

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To investigate whether serum procalcitonin (PCT) levels could be useful to differentiate between systemic infection and the activity of the underlying disease in autoimmune disease. METHODS:In 18 patients with systemic lupus erythematodes (SLE) and 35 patients with systemic antineutrophil cytoplasmic antibod...

journal_title：Intensive care medicine

authors： Brunkhorst R,Eberhardt OK,Haubitz M,Brunkhorst FM

更新日期：2000-03-01 00:00:00

abstract：:The acute respiratory distress syndrome (ARDS) continues as a contributor to the morbidity and mortality of patients in intensive care units throughout the world, imparting tremendous human and financial costs. During the last ten years there has been a decline in ARDS mortality without a clear explanation. The Americ...

journal_title：Intensive care medicine

authors： Artigas A,Bernard GR,Carlet J,Dreyfuss D,Gattinoni L,Hudson L,Lamy M,Marini JJ,Matthay MA,Pinsky MR,Spragg R,Suter PM

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:To determine the influence of religious affiliation and culture on end-of-life decisions in European intensive care units (ICUs). DESIGN AND SETTING:A prospective, observational study of European ICUs was performed on consecutive patients with any limitation of therapy. Prospectively defined end-of-life prac...

journal_title：Intensive care medicine

authors： Sprung CL,Maia P,Bulow HH,Ricou B,Armaganidis A,Baras M,Wennberg E,Reinhart K,Cohen SL,Fries DR,Nakos G,Thijs LG,Ethicus Study Group.

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:Previous observational studies have inconsistently associated early hyperoxia with worse outcomes after cardiac arrest, and have methodological limitations. We tested this association using a high-resolution database controlling for multiple disease-specific markers of severity of illness and care processes. M...

journal_title：Intensive care medicine

authors： Elmer J,Scutella M,Pullalarevu R,Wang B,Vaghasia N,Trzeciak S,Rosario-Rivera BL,Guyette FX,Rittenberger JC,Dezfulian C,Pittsburgh Post-Cardiac Arrest Service (PCAS).

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:Computerized clinical decision support systems (CDSS) for intensive insulin therapy (IIT) generate recommendations using blood glucose (BG) values manually transcribed from testing devices to computers, a potential source of error. We quantified the frequency and effect of blood glucose transcription mismatches...

journal_title：Intensive care medicine

authors： Campion TR Jr,May AK,Waitman LR,Ozdas A,Gadd CS

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To compare some of the confirmatory investigations of brain death with clinical criteria in order to achieve the most sensitive and accurate diagnosis of brain death. DESIGN:All patients with isolated brain lesions and Glasgow Coma Scale (GCS) = 3 were subjected to neurological examination after ruling out h...

journal_title：Intensive care medicine

authors： Paolin A,Manuali A,Di Paola F,Boccaletto F,Caputo P,Zanata R,Bardin GP,Simini G

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Trustworthy clinical practice guidelines (CPGs) require identification and careful management of conflicts of interest (COIs) among all participants in the guideline development. Furthermore, COIs are more common than anticipated. However, there are no universally accepted methods to identify and manage COIs...

journal_title：Intensive care medicine

authors： Alhazzani W,Lewis K,Jaeschke R,Rochwerg B,Møller MH,Evans L,Wilson KC,Patel S,Coopersmith CM,Cecconi M,Guyatt G,Akl EA

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between the base deficit value in the immediate postoperative period of coronary surgery for cardiopulmonary bypass and the length of stay in the ICU. DESIGN AND SETTING:Prospective descriptive study in the department of anesthesia and cardiovascular surgery of a university hospita...

journal_title：Intensive care medicine

authors： Hugot P,Sicsic JC,Schaffuser A,Sellin M,Corbineau H,Chaperon J,Ecoffey C

更新日期：2003-02-01 00:00:00

abstract：PURPOSE:To provide evidence-based guidelines for early enteral nutrition (EEN) during critical illness. METHODS:We aimed to compare EEN vs. early parenteral nutrition (PN) and vs. delayed EN. We defined "early" EN as EN started within 48 h independent of type or amount. We listed, a priori, conditions in which EN is o...

journal_title：Intensive care medicine

authors： Reintam Blaser A,Starkopf J,Alhazzani W,Berger MM,Casaer MP,Deane AM,Fruhwald S,Hiesmayr M,Ichai C,Jakob SM,Loudet CI,Malbrain ML,Montejo González JC,Paugam-Burtz C,Poeze M,Preiser JC,Singer P,van Zanten AR,De Waele J

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:We undertook this study to evaluate the influence of the inspiration:expiration (I:E) ratio on intracranial pressure and cerebral perfusion in patients with acute stroke. DESIGN:Ventilated patients with acute stroke were examined under a protocol involving variations of I:E ratio from 1:2 to 1:1 to 1:2 under...

journal_title：Intensive care medicine

authors： Georgiadis D,Schwarz S,Kollmar R,Baumgartner RW,Schwab S

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To assess the outcome of intensive care unit (ICU) treatment in patients with hematological malignancies. DESIGN AND SETTING:Retrospective cohort study in the medical ICU of a university hospital. PATIENTS:104 critically ill patients after receiving conventional chemotherapy or autologous hematopoietic stem...

journal_title：Intensive care medicine

authors： Kroschinsky F,Weise M,Illmer T,Haenel M,Bornhaeuser M,Hoeffken G,Ehninger G,Schuler U

更新日期：2002-09-01 00:00:00

abstract：:In the first study 6 patients with raised intracranial pressure due to brain oedema following head injury were given dihydroergotamine because of low perfusion pressure. The intracranial pressure fell simultaneously with the increase in arterial pressure. The intracranial pressure fell from 24 +/- 2 mmHg by a maximum ...

journal_title：Intensive care medicine

authors： Grände PO

更新日期：1989-01-01 00:00:00

abstract：INTRODUCTION:Microcirculatory abnormalities are frequently observed in patients with severe heart failure and correlate to worse outcomes. We tested the hypothesis that nitroglycerin dose-dependently improves perfusion in severe heart failure and that this could be monitored by measuring central-peripheral temperature ...

journal_title：Intensive care medicine

authors： den Uil CA,Caliskan K,Lagrand WK,van der Ent M,Jewbali LS,van Kuijk JP,Spronk PE,Simoons ML

更新日期：2009-11-01 00:00:00

abstract：:In 9 Goettingen minipigs we studied the effect of E. coli bacteremia on effective pulmonary capillary pressure and the longitudinal distribution of pulmonary vascular resistance. Precapillary pressure gradient (dPa) was calculated as the difference between mean pulmonary artery pressure (MPP) and effective pulmonary c...

journal_title：Intensive care medicine

authors： Fretschner R,Klöss T,Guggenberger H,Heuser D,Schmid HJ,Widmann M

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Current medical knowledge lacks specific information regarding creatine kinase (CK) elevation in influenza A pH1N1 (2009) infection. OBJECTIVES:Primary endpoints were correlation between CK at intensive care unit (ICU) admission and ICU mortality. Secondary endpoints were ICU length of stay (LOS), mechanica...

journal_title：Intensive care medicine

authors： Borgatta B,Pérez M,Rello J,Vidaur L,Lorente L,Socías L,Pozo JC,Pozo J,Garnacho-Montero J,Rello J,pH1N1 GTEI\/SEMICYUC.

更新日期：2012-07-01 00:00:00