Influence of inspiration:expiration ratio on intracranial and cerebral perfusion pressure in acute stroke patients.

abstract：OBJECTIVES:To measure plasma levels and pharmacokinetics of cefpirome in critically ill septic patients with normal renal function. To use the pharmacokinetic model to simulate alternate dosing regimens and identify those that predict sustained levels. DESIGN AND SETTING:A prospective, open-label, descriptive study in...

journal_title：Intensive care medicine

authors： Lipman J,Wallis SC,Rickard CM,Fraenkel D

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:To investigate nasal nitric oxide (NO) excretion, pulmonary NO excretion, and autoinhalation of nasally released NO at rest compared with that during moderate exercise in smokers and non-smokers. DESIGN:Prospective observational study. SETTING:University laboratory. PARTICIPANTS:Fourteen healthy adult volu...

journal_title：Intensive care medicine

authors： Busch T,Kuhlen R,Knorr M,Kelly K,Lewandowski K,Rossaint R,Falke KJ,Gerlach H

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:Alterations in coagulation, including elevated pulmonary and systemic concentrations of urokinase, are frequent in patients with acute lung injury (ALI). Urokinase potentiates neutrophil activation and contributes to the severity of pulmonary injury in preclinical models of ALI. The objective of this study wa...

journal_title：Intensive care medicine

authors： Arcaroli J,Sankoff J,Liu N,Allison DB,Maloney J,Abraham E

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:Pneumonia associated with invasive mechanical ventilation (IMV) is one of the indicator infections of the German Nosocomial Infection Surveillance System. In 2005 surveillance was extended to include pneumonia associated with noninvasive ventilation (NIV). The aim of this study was to determine the utilization ...

journal_title：Intensive care medicine

authors： Kohlenberg A,Schwab F,Behnke M,Geffers C,Gastmeier P

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:Inflammatory markers may have a role in predicting severity of illness of intensive care unit (ICU) patients. The aim of this study is to determine whether low eosinophil count can predict 28-day mortality in medical ICU. METHODS:A prospective study over a 4-month period. To evaluate the prognosis information ...

journal_title：Intensive care medicine

authors： Abidi K,Belayachi J,Derras Y,Khayari ME,Dendane T,Madani N,Khoudri I,Zeggwagh AA,Abouqal R

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To determine the relation of malnutrition and underlying diagnosis to the length of stay in the Intensive Care Unit (ICU) and to mortality after lung transplantation (LTX). DESIGN:Retrospective ICU chart review. SETTING:Cardiothoracic ICU in a University hospital. PATIENTS:Fifty-one consecutive patients wh...

journal_title：Intensive care medicine

authors： Plöchl W,Pezawas L,Artemiou O,Grimm M,Klepetko W,Hiesmayr M

更新日期：1996-11-01 00:00:00

abstract：:In a randomized clinical trial the prophylactic effects of locally administered antimicrobials on quantitative colonization and respiratory infections were studied in intubated patients with an expected period of mechanical ventilation of greater than 6 days. Nineteen patients received 50 mg of polymyxin B and 80 mg o...

journal_title：Intensive care medicine

authors： Unertl K,Ruckdeschel G,Selbmann HK,Jensen U,Forst H,Lenhart FP,Peter K

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:Endotoxin administration to humans is a common means to study systemic inflammation. Worldwide, thousands of volunteers have received endotoxin, and adverse events are rarely reported. The aim of this report was to increase awareness of specific risks of the intravenous administration of endotoxin to human vo...

journal_title：Intensive care medicine

authors： van Eijk LT,Pickkers P,Smits P,Bouw MP,van der Hoeven JG

更新日期：2004-12-01 00:00:00

abstract：PURPOSE:We evaluated whether oscillatory compliance (C(X5)) measured by forced oscillation technique (FOT) at 5 Hz may be useful for positive end-expiratory pressure (PEEP) optimisation. METHODS:We studied seven pigs in which lung injury was induced by broncho-alveolar lavage. The animals were ventilated in volume con...

journal_title：Intensive care medicine

authors： Dellacà RL,Zannin E,Kostic P,Olerud MA,Pompilio PP,Hedenstierna G,Pedotti A,Frykholm P

更新日期：2011-06-01 00:00:00

abstract：:A hypertensive crisis with an arterial blood pressure of 280/180 mmHg developed immediately after an apparently successful removal of a phaeochromocytoma. The blood pressure could not be lowered by phentolamine and not until the administration of dihydralazine and furosemide was the systemic pressure normalized. In ad...

journal_title：Intensive care medicine

authors： Johansson H,Brismar B,Hedenstierna G

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:Measurement of functional residual capacity (FRC) during controlled and especially during assisted ventilation remains a challenge in the physiological evaluation of ventilated patients. To validate a bag-in-box closed helium dilution technique allowing measurements both during pressure-controlled (PCV) and p...

journal_title：Intensive care medicine

authors： Di Marco F,Rota Sperti L,Milan B,Stucchi R,Centanni S,Brochard L,Fumagalli R

更新日期：2007-12-01 00:00:00

abstract：:We describe a case of the dialysis disequilibrium syndrome (DDS) that was marked by the rapid onset of cerebral edema and the subsequent development of acute respiratory failure. The patient was treated successfully with a combination of mechanical hyperventilation and mannitol. The clinical presentation, pathogenesis...

journal_title：Intensive care medicine

authors： DiFresco V,Landman M,Jaber BL,White AC

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:Fibroproliferation markers like procollagen I predict mortality in patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). We sought to determine whether bronchoalveolar lavage fluid (BALF) from patients with lung injury contained mediators that would activate procollagen I promo...

journal_title：Intensive care medicine

authors： Budinger GR,Chandel NS,Donnelly HK,Eisenbart J,Oberoi M,Jain M

更新日期：2005-01-01 00:00:00

abstract：:The effects of 142 intravenous boluses of althesin (0.05 ml/kg) on cerebral perfusion pressure (CPP) were studied in twelve head injured comatose patients. The data were divided into those where the mean pre-bolus intracranial pressure (ICP) was above or below 20 mmHg and then subdivided into those where the minimum p...

journal_title：Intensive care medicine

authors： Procaccio F,Bingham RM,Hinds CJ,Prior PF

更新日期：1988-01-01 00:00:00

abstract：:In alcoholic patients, metabolic acidosis can be related to lactate acidosis associated with sepsis or thiamine deficiency, ketoacidosis, methanol or ethylene glycol poisoning. High resolution proton nuclear magnetic resonance (NMR) can be used to detect abnormal organic acid metabolites in urine or serum from patient...

journal_title：Intensive care medicine

authors： Godet C,Hira M,Adoun M,Eugène M,Robert R

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:Inhalation of high concentrations of nitric oxide (NO) has been shown to improve gas exchange and to reduce pulmonary vascular resistance in individuals with ischemia-reperfusion injury following orthotopic lung transplantation. We assessed the cardiopulmonary effects of low doses of NO in early allograft dys...

journal_title：Intensive care medicine

authors： Kemming GI,Merkel MJ,Schallerer A,Habler OP,Kleen MS,Haller M,Briegel J,Vogelmeier C,Fürst H,Reichart B,Zwissler B

更新日期：1998-11-01 00:00:00

abstract：PURPOSE:Recalibration and determining discriminative power, internationally, of the existing delirium prediction model (PRE-DELIRIC) for intensive care patients. METHODS:A prospective multicenter cohort study was performed in eight intensive care units (ICUs) in six countries. The ten predictors (age, APACHE-II, urgen...

journal_title：Intensive care medicine

authors： van den Boogaard M,Schoonhoven L,Maseda E,Plowright C,Jones C,Luetz A,Sackey PV,Jorens PG,Aitken LM,van Haren FM,Donders R,van der Hoeven JG,Pickkers P

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the physiological effects of decannulation on breathing patterns and respiratory mechanics by comparing mouth breathing (MB) to tracheal breathing (TB) in tracheostomized patients. DESIGN AND SETTING:Prospective cross-over study in a critical and neuromuscular care unit. PATIENTS AND METHODS:Nin...

journal_title：Intensive care medicine

authors： Chadda K,Louis B,Benaïssa L,Annane D,Gajdos P,Raphaël JC,Lofaso F

更新日期：2002-12-01 00:00:00

abstract：:The effect of enteral feeding on O2-consumption (VO2) and CO2-production (VCO2) was studied in 9 ventilator-dependent patients, who were in a stable condition without signs of hypermetabolism. Resting energy expenditure (REE) in postabsorptive state was assessed and enteral feeding was started by continuous drip (480 ...

journal_title：Intensive care medicine

authors： van den Berg B,Stam H

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of nicotinamide (NIC), an inhibitor of poly(ADP-ribose) synthetase (PARS), on intestinal and liver perfusion, O2 kinetics, and energy metabolism over 24 h of hyperdynamic porcine endotoxemia. DESIGN:Prospective, randomized, controlled experimental study with repeated measures. SET...

journal_title：Intensive care medicine

authors： Theisen M,Träger K,Tugtekin I,Stehr A,Ploner F,Georgieff M,Radermacher P,Matĕjovic M

更新日期：2001-03-01 00:00:00

abstract：PURPOSE:To use the World Health Organisation's International Classification of Functioning to measure disability following critical illness using patient-reported outcomes. METHODS:A prospective, multicentre cohort study conducted in five metropolitan intensive care units (ICU). Participants were adults who had been a...

journal_title：Intensive care medicine

authors： Hodgson CL,Udy AA,Bailey M,Barrett J,Bellomo R,Bucknall T,Gabbe BJ,Higgins AM,Iwashyna TJ,Hunt-Smith J,Murray LJ,Myles PS,Ponsford J,Pilcher D,Walker C,Young M,Cooper DJ

更新日期：2017-07-01 00:00:00

abstract：:Recent advances in analytical electrochemistry have provided highly selective potassium ion exchangers and robust polymeric membranes that can be used to measure the potassium activity in plasma or whole blood. The relationship between the activity measurement and the more familiar concentration measurement is explore...

journal_title：Intensive care medicine

authors： Treasure T

更新日期：1978-04-01 00:00:00

abstract：:As a result of the previous shortage of tools to assess objectively the overall physiological status of the respiratory system in infants and young children, it has been difficult to measure the degree of physiological disorder or the response to therapy in respiratory diseases such as BPD, the pediatric version of AR...

journal_title：Intensive care medicine

authors： Hammer J,Newth CJ

更新日期：1995-09-01 00:00:00

abstract：:The increase of the inflationary lung volume created by a respiratory maneuver is critical for preventing postoperative alveolar collapse. We measured this volume as achieved with IPPB or incentive spirometry (IS) in 20 postoperative surgical patients. Using IPPB, with gas flow and peak airway pressures carefully adju...

journal_title：Intensive care medicine

authors： Pfenninger J,Roth F

更新日期：1977-12-01 00:00:00

abstract：OBJECTIVE:The role of critical care pharmacists in the United States has recently been documented; however, little information exists about the role of international critical care pharmacists. The objective of this study was to describe the duties and activities of international pharmacists who practice in critical car...

journal_title：Intensive care medicine

authors： LeBlanc JM,Seoane-Vazquez EC,Arbo TC,Dasta JF

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To report the feasibility of craniectomy with duraplasty in four patients with life-threatening encephalitis and, in particular, their long-term outcome. DESIGN:Report of four cases, analysis of the acute clinical course and neurological long-term sequelae. RESULTS:Generous craniectomy with duraplasty was p...

journal_title：Intensive care medicine

authors： Taferner E,Pfausler B,Kofler A,Spiss H,Engelhardt K,Kampfl A,Schmutzhard E

更新日期：2001-08-01 00:00:00

abstract：PURPOSE:Severe acute pancreatitis (SAP) remains a life-threatening disease with classic etiology of systemic inflammatory response and mortality between 30 and 50 %. The aim of the present study is to compare two different treatment strategies of goal-directed hemodynamic management and evaluate their impact on surviva...

journal_title：Intensive care medicine

authors： Trepte CJ,Bachmann KA,Stork JH,Friedheim TJ,Hinsch A,Goepfert MS,Mann O,Izbicki JR,Goetz AE,Reuter DA

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:Evaluating the prevalence, risk factors and prevention of pressure ulcers in Dutch intensive care units (ICUs). DESIGN:Cross-sectional design. SETTING:ICUs of acute care hospitals that participated in the 1998 and 1999 national prevalence surveys. Data were collected on 1 day in each year. PATIENTS:Eight h...

journal_title：Intensive care medicine

authors： Bours GJ,De Laat E,Halfens RJ,Lubbers M

更新日期：2001-10-01 00:00:00

abstract：PURPOSE:We set out to summarize the current challenges in academic conflict of interest. METHODS:This is a narrative review by a multidisciplinary, multinational panel of academic officers including deans of medical/pharmacy schools. RESULTS AND CONCLUSIONS:Disclosing conflict of interest has become the appropriate p...

journal_title：Intensive care medicine

authors： Annane D,Lerolle N,Meuris S,Sibilla J,Olsen KM

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To apply the modified pediatric RIFLE criteria for severity of acute kidney injury (AKI) to pediatric burn ICU patients and to evaluate the overall incidence of AKI, risk factors for AKI and influence of AKI on outcome. DESIGN:Retrospective, descriptive cohort study. SETTING:10-bed burn PICU facility. PATI...

journal_title：Intensive care medicine

authors： Palmieri T,Lavrentieva A,Greenhalgh D

更新日期：2009-12-01 00:00:00