Rapid diagnosis of alcoholic ketoacidosis by proton NMR.

Abstract:

:In alcoholic patients, metabolic acidosis can be related to lactate acidosis associated with sepsis or thiamine deficiency, ketoacidosis, methanol or ethylene glycol poisoning. High resolution proton nuclear magnetic resonance (NMR) can be used to detect abnormal organic acid metabolites in urine or serum from patients with various metabolic disorders. In the present case, a 26-year-old patient was admitted for a coma associated with severe metabolic acidosis. Alcoholic ketoacidosis (AKA) was identified by urine proton NMR. Her metabolic disorders rapidly improved. Persisting associated neurological alteration was related to extrapontine myelinolysis as shown by imaging cerebral NMR.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Godet C,Hira M,Adoun M,Eugène M,Robert R

doi

10.1007/s001340100892

keywords:

subject

Has Abstract

pub_date

2001-04-01 00:00:00

pages

785-6

issue

4

eissn

0342-4642

issn

1432-1238

journal_volume

27

pub_type

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