Short-term evaluation of sedation with sevoflurane administered by the anesthetic conserving device in critically ill patients.

abstract：PURPOSE:Frail patients are known to experience poor outcomes. Nevertheless, we know less about how frailty manifests itself in patients' physiology during critical illness and how it affects resource use in intensive care units (ICU). We aimed to assess the association of frailty with short-term outcomes and organ supp...

journal_title：Intensive care medicine

authors： Zampieri FG,Iwashyna TJ,Viglianti EM,Taniguchi LU,Viana WN,Costa R,Corrêa TD,Moreira CEN,Maia MO,Moralez GM,Lisboa T,Ferez MA,Freitas CEF,de Carvalho CB,Mazza BF,Lima MFA,Ramos GV,Silva AR,Bozza FA,Salluh JIF,Soar

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the physiological effects of decannulation on breathing patterns and respiratory mechanics by comparing mouth breathing (MB) to tracheal breathing (TB) in tracheostomized patients. DESIGN AND SETTING:Prospective cross-over study in a critical and neuromuscular care unit. PATIENTS AND METHODS:Nin...

journal_title：Intensive care medicine

authors： Chadda K,Louis B,Benaïssa L,Annane D,Gajdos P,Raphaël JC,Lofaso F

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the usefulness of early transcranial Doppler ultrasound (TCD) goal-directed therapy after severe traumatic brain injury initiated before invasive cerebral monitoring is available. DESIGN:Prospective, observational clinical study. SETTING:Surgical intensive care unit, university hospital. PATIEN...

journal_title：Intensive care medicine

authors： Ract C,Le Moigno S,Bruder N,Vigué B

更新日期：2007-04-01 00:00:00

abstract：: ...

journal_title：Intensive care medicine

authors： Varkila MRJ,Cremer OL

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:Transcapillary heat transfer after injections of cold saline into the right atrium generates bronchial thermodilution curves resembling those observed in the aorta. Under the assumption that no indicator is lost or gained within the pulmonary capillary bed and changes in blood temperature are instantaneously ...

journal_title：Intensive care medicine

authors： Loer SA,Wietasch JK,Scheeren TW

更新日期：1999-02-01 00:00:00

abstract：PURPOSE:Motion-mode (MM) echography allows precise measurement of diaphragmatic excursion when the ultrasound beam is parallel to the diaphragmatic displacement. However, proper alignment is difficult to obtain in patients after cardiac surgery; thus, measurements might be inaccurate. A new imaging modality named the a...

journal_title：Intensive care medicine

authors： Pasero D,Koeltz A,Placido R,Fontes Lima M,Haun O,Rienzo M,Marrache D,Pirracchio R,Safran D,Cholley B

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:We assessed outcomes in brain-injured patients after implementation of a multi-faceted approach to reduce respiratory complications in intensive care units. METHODS:Prospective nationwide before-after trial. Consecutive adults with acute brain injury requiring mechanical ventilation for ≥24 h in 20 French inte...

journal_title：Intensive care medicine

authors： Asehnoune K,Mrozek S,Perrigault PF,Seguin P,Dahyot-Fizelier C,Lasocki S,Pujol A,Martin M,Chabanne R,Muller L,Hanouz JL,Hammad E,Rozec B,Kerforne T,Ichai C,Cinotti R,Geeraerts T,Elaroussi D,Pelosi P,Jaber S,Dalicha

更新日期：2017-07-01 00:00:00

abstract：:Nosocomial pneumonia continues to represent a significant cause of morbidity and mortality in hospitalized patients. Bacteria are responsible for greater than 90% of the pneumonias, the most common isolates being aerobic Gram-negative bacilli and S. aureus. Cornerstones of treatment are intravenous antibiotics and sup...

journal_title：Intensive care medicine

authors： Unertl KE,Lenhart FP,Forst H,Peter K

更新日期：1992-01-01 00:00:00

abstract：:A study was conducted to evaluate repeated intrathecal injections of baclofen, without artificial ventilation, in the treatment of severe tetanus. Ten patients, 5 men and 5 women, with a mean age of 34 +/- 7 years, were included in the study. The dose of baclofen injected was 1000 micrograms between the ages of 16 and...

journal_title：Intensive care medicine

authors： Saissy JM,Demazière J,Vitris M,Seck M,Marcoux L,Gaye M,Ndiaye M

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To describe the syndrome of rhabdomyolysis during bacterial sepsis with regard to incidence, blood bacteriology and complications and to examine the association between hyperosmolal state and rhabdomyolysis, evaluating the relationship between plasma osmolality (Posm) and serum creatine phosphokinase (CPK) le...

journal_title：Intensive care medicine

authors： Betrosian A,Thireos E,Kofinas G,Balla M,Papanikolaou M,Georgiadis G

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:To investigate ventilation-perfusion (VA/Q) relationships, during continuous axial rotation and in the supine position, in patients with acute lung injury (ALI) using the multiple inert gas elimination technique. DESIGN:Prospective investigation. SETTING:Eighteen-bed intensive care unit in a university hosp...

journal_title：Intensive care medicine

authors： Bein T,Reber A,Metz C,Jauch KW,Hedenstierna G

更新日期：1998-02-01 00:00:00

abstract：INTRODUCTION:Faecal peritonitis (FP) is a common cause of sepsis and admission to the intensive care unit (ICU). The Genetics of Sepsis and Septic Shock in Europe (GenOSept) project is investigating the influence of genetic variation on the host response and outcomes in a large cohort of patients with sepsis admitted t...

journal_title：Intensive care medicine

authors： Tridente A,Clarke GM,Walden A,McKechnie S,Hutton P,Mills GH,Gordon AC,Holloway PA,Chiche JD,Bion J,Stuber F,Garrard C,Hinds CJ,GenOSept Investigators.

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:a) to describe a non-barotraumatic ventilatory setting for independent lung ventilation (ILV); b) to determine the utility of single lung end-tidal CO(2) (EtCO(2)) monitoring to evaluate the ventilation to perfusion (V/Q) matching in each lung during ILV and for ILV weaning. DESIGN:prospective study. SETTIN...

journal_title：Intensive care medicine

authors： Cinnella G,Dambrosio M,Brienza N,Giuliani R,Bruno F,Fiore T,Brienza A

更新日期：2001-12-01 00:00:00

abstract：: ...

journal_title：Intensive care medicine

authors： Perner A,Finfer S

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:Postoperative pneumonia is a potentially devastating complication associated with high mortality in intensive care unit (ICU)-patients. One of the major predisposing factors is the perioperative occurrence of atelectatic formations in non-dependent lung areas. Perioperative ventilation/perfusion mismatch due ...

journal_title：Intensive care medicine

authors： Hutschala D,Kinstner C,Skhirtladze K,Mayer-Helm BX,Zeitlinger M,Wisser W,Müller M,Tschernko E

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVES:To examine whether urgent orotracheal intubation (OI) can induce bacteremia. To find predictive factors for post-intubation bacteremia. DESIGN:Prospective observational study. SETTING:Seventeen-bed medical intensive care unit in a university hospital. PATIENTS:Sixty-eight adult intensive care patients und...

journal_title：Intensive care medicine

authors： Rijnders BJ,Wilmer A,Van Eldere J,Van Wijngaerden E

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:We compared two imipenem regimens for prevention of septic complications in patients with severe acute necrotizing pancreatitis (ANP). DESIGN AND SETTING:Prospective, randomized open clinical trial involving intensive care units of 14 Spanish Hospitals. PARTICIPANTS:92 patients with ANP. INTERVENTIONS:Imip...

journal_title：Intensive care medicine

authors： Maraví-Poma E,Gener J,Alvarez-Lerma F,Olaechea P,Blanco A,Domínguez-Muñoz JE,Spanish Group for the Study of Septic Complications in Severe Acute Pancreatitis.

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of screening strategy and contact precautions for patients with methicillin-resistant Staphylococcus aureus (MRSA). DESIGN AND SETTING:Prospective observational cohort from 1 February 1995 to 31 December 2001 in three intensive care units (45 beds) in a French teaching hospital....

journal_title：Intensive care medicine

authors： Lucet JC,Paoletti X,Lolom I,Paugam-Burtz C,Trouillet JL,Timsit JF,Deblangy C,Andremont A,Regnier B

更新日期：2005-08-01 00:00:00

abstract：PURPOSE:To study the incidence and clinical characteristics of delayed cerebral thrombosis in bacterial meningitis patients. METHODS:We assessed the incidence and clinical characteristics of delayed cerebral thrombosis in adults with cerebrospinal fluid (CSF) culture-proven community-acquired bacterial meningitis incl...

journal_title：Intensive care medicine

authors： Lucas MJ,Brouwer MC,van de Beek D

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To investigate the accuracy of lung ultrasonography (LUS) in the quantification of lung water in critically ill patients by using quantitative computed tomography (CT) as the gold standard for the determination of lung weight. METHODS:Twenty consecutive patients admitted to an intensive care unit who underwe...

journal_title：Intensive care medicine

authors： Baldi G,Gargani L,Abramo A,D'Errico L,Caramella D,Picano E,Giunta F,Forfori F

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:Sedatives administered to critically ill children should be titrated to effect, because both under- and oversedation may have negative effects. We conducted a systematic review to examine reported incidences of under-, optimal, and oversedation in critically ill children receiving intensive care. METHODS:A sys...

journal_title：Intensive care medicine

authors： Vet NJ,Ista E,de Wildt SN,van Dijk M,Tibboel D,de Hoog M

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:We perform an ethical analysis of European Union Directive 2001/20/EC on the simplification and harmonization of guidelines regarding good clinical practice in the conduct of clinical trials involving drugs. BACKGROUND:The Directive provides guidance on protecting incapacitated subjects who participate in dr...

journal_title：Intensive care medicine

authors： Silverman HJ,Druml C,Lemaire F,Nelson R,European Union Directive.

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:The Pediatric Index of Mortality 2 (PIM2), one of the key mortality prediction models for children in intensive care units, has not been validated in Japan. The purpose of this study was to validate the performance of PIM2 in a population of patients admitted to one pediatric intensive care unit (PICU) in Jap...

journal_title：Intensive care medicine

authors： Imamura T,Nakagawa S,Goldman RD,Fujiwara T

更新日期：2012-04-01 00:00:00

abstract：:A prospective study of thiamine status in patients with severe injuries (injury severity scores greater than 12) showed that they all developed signs of severe thiamine deficiency on the basis of transketolase activity, the standard biochemical test for thiamine deficiency. This occurred within the first week after th...

journal_title：Intensive care medicine

authors： McConachie I,Haskew A

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:Neutrophil gelatinase-associated lipocalin (NGAL) is a promising biomarker for acute kidney injury (AKI). We evaluated the diagnostic and prognostic accuracies of plasma NGAL (pNGAL) for contrast-induced AKI (CI-AKI) in critically ill patients. METHODS:In a prospective observational study in two adult intensiv...

journal_title：Intensive care medicine

authors： Valette X,Savary B,Nowoczyn M,Daubin C,Pottier V,Terzi N,Seguin A,Fradin S,Charbonneau P,Hanouz JL,du Cheyron D

更新日期：2013-05-01 00:00:00

abstract：:The goals of management of patients with respiratory failure include improving arterial oxygenation with PEEP and red cell transfusion to maintain oxygen carrying capacity, both of which contribute to improving tissue oxygen delivery. However, standard CPD-stored blood is rapidly depleted of 2,3 diphosphoglycerate (2,...

journal_title：Intensive care medicine

authors： Kahn RC,Zaroulis C,Goetz W,Howland WS

更新日期：1986-01-01 00:00:00

abstract：:Intravenous bolus endotoxin elicits a marked but transient increase in plasma TxB2 and 6-keto-PGF1 alpha in a large number of species. A smaller, delayed and more prolonged increase in TxB2 and 6-keto-PGF1 alpha are reported in animals with septic shock, i.e., those with fecal peritonitis or cecal ligation. Thromboxan...

journal_title：Intensive care medicine

authors： Ball HA,Cook JA,Wise WC,Halushka PV

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:Candida spp. airway colonization could promote development of ventilator-associated pneumonia (VAP) caused by Pseudomonas aeruginosa, a potentially multidrug-resistant (MDR) bacteria, and worsen the outcome of VAP regardless of pathogen. We therefore address the question of the risk of MDR bacteria isolation ...

journal_title：Intensive care medicine

authors： Hamet M,Pavon A,Dalle F,Pechinot A,Prin S,Quenot JP,Charles PE

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Infection is the most frequent cause of acute respiratory distress syndrome (ARDS). However, little is known about the influence of infection sites on ARDS. This study aimed to assess the associations of infection sites with ARDS development and mortality in critically ill infected patients. DESIGN:Prospecti...

journal_title：Intensive care medicine

authors： Sheu CC,Gong MN,Zhai R,Bajwa EK,Chen F,Thompson BT,Christiani DC

更新日期：2010-06-01 00:00:00

abstract：:We evaluated the effect of a cimetidine continuous infusion (2 g in 24 h) on the intragastric pH of 16 critically ill patients (11 men, 5 women, mean age 45 years). During the 24 h pre-trial period and the subsequent 24 h cimetidine infusion, an intragastric combined electrode was placed in the fundus and the pH recor...

journal_title：Intensive care medicine

authors： Tomé G,Fiasse R,Reynaert M,Mahieu P,Hanssens F

更新日期：1988-01-01 00:00:00