当前位置： SCI文献检索 > INTENSIVE CARE MEDICINE期刊下所有文献 > Successful long-term program for controlling methicillin-resistant Staphylococcus aureus in intensive care units.

Successful long-term program for controlling methicillin-resistant Staphylococcus aureus in intensive care units.

Abstract：

OBJECTIVE:To evaluate the effectiveness of screening strategy and contact precautions for patients with methicillin-resistant Staphylococcus aureus (MRSA). DESIGN AND SETTING:Prospective observational cohort from 1 February 1995 to 31 December 2001 in three intensive care units (45 beds) in a French teaching hospital. PATIENTS:8,548 patients admitted to the three ICUs had nasal screening on ICU admission and weekly thereafter. Contact precautions were used in MRSA-positive patients. The following variables were collected: age, gender, severity score, length of stay, workload, and colonization pressure (percentage of patient-days with an MRSA to the number of patient-days in the unit). Alcohol-based handrub solution was introduced in July 2000. We compared the period before this (P1) with that thereafter (P2). RESULTS:Of the 8,548 admitted patients 554 (6.5%) had MRSA at ICU admission, and 456 of the 7,515 (6.1%) exposed patients acquired MRSA. Acquisition incidence decreased from 7.0% in P1 to 2.8% in P2. Independent variables associated with MRSA acquisition were: age (adjusted odds ratio 1.013), severity score (1.047), length of ICU stay (1.015), colonization pressure (1.019), medical ICU (1.58), and P2 (0.49). CONCLUSIONS:MRSA control in these ICUs characterized by a high prevalence of MRSA at admission was achieved via multiple factors, including screening, contact precautions, and use of alcoholic handrub solution. Our results after adjustment of risk factors for MRSA acquisition and the steady improvement in MRSA over several years strengthen these findings. MRSA spreading can be successfully controlled in ICUs with high colonization pressure.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Lucet JC,Paoletti X,Lolom I,Paugam-Burtz C,Trouillet JL,Timsit JF,Deblangy C,Andremont A,Regnier B

doi

10.1007/s00134-005-2679-0

keywords:

subject

Has Abstract

pub_date

2005-08-01 00:00:00

pages

1051-7

issue

8

eissn

0342-4642

issn

1432-1238

journal_volume

31

pub_type

杂志文章

相关文献

INTENSIVE CARE MEDICINE文献大全
  • Assessment of the inflammatory effect of low-dose oxygen in mechanically ventilated patients.

    abstract：PURPOSE:Although low doses of oxygen (FiO2 <0.50) are considered nontoxic, recent studies have shown that even lower doses increase pulmonary inflammatory mediators. We aimed to evaluate the acute effects of reducing FiO2 on pulmonary inflammation in mechanically ventilated patients without respiratory failure. METHOD...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-012-2801-z

    authors： Fernandez R,Gili G,Villagra A,Lopez-Aguilar J,Artigas A

    更新日期：2013-04-01 00:00:00

  • Description of trends in the course of illness of critically ill patients. Markers of intensive care organization and performance.

    abstract：OBJECTIVE:To identify objective trends of the course of illness that might be used as benchmarks in the auditing of the organization/performance of Intensive Care Units (ICU). DESIGN:Retrospective analysis. PATIENTS AND SETTING:A group of 12,615 patients and 55,464 patient-days prospectively collected in 89 ICUs of 1...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-002-1331-5

    authors： Iapichino G,Radrizzani D,Ferla L,Pezzi A,Porta F,Zanforlin G,Miranda DR

    更新日期：2002-07-01 00:00:00

  • Blood lactate levels are better prognostic indicators than TNF and IL-6 levels in patients with septic shock.

    abstract：OBJECTIVE:Both serum levels of tumor necrosis factor-alpha (TNF alpha) and interleukin-6 (IL-6) and blood lactate levels in patients with septic shock have been shown to correlate with prognosis. The aim of the study was to define the relative predictive value of these measures. PATIENTS:38 hospitalized patients with ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01712155

    authors： Marecaux G,Pinsky MR,Dupont E,Kahn RJ,Vincent JL

    更新日期：1996-05-01 00:00:00

  • Coagulation Day 2010: an Austrian survey on the routine of thromboprophylaxis in intensive care.

    abstract：PURPOSE:Venous thromboembolism (VTE) is a common but often overlooked life-threatening complication of critical illness. The aim of this cross-sectional survey was to assess current practice of thromboprophylaxis as well as adherence to international guidelines. METHODS:After ethics committee approval, all intensive c...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-012-2533-0

    authors： Schaden E,Metnitz PG,Pfanner G,Heil S,Pernerstorfer T,Perger P,Schoechl H,Fries D,Guetl M,Kozek-Langenecker S

    更新日期：2012-06-01 00:00:00

  • Procalcitonin for early diagnosis and differentiation of SIRS, sepsis, severe sepsis, and septic shock.

    abstract：OBJECTIVE:To determine the value of procalcitonin (PCT) in the early diagnosis (and differentiation) of patients with SIRS, sepsis, severe sepsis, and septic shock in comparison to C-reactive protein (CRP), white blood cell and thrombocyte count, and APACHE-II score (AP-II). DESIGN:Prospective cohort study including a...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF02900728

    authors： Brunkhorst FM,Wegscheider K,Forycki ZF,Brunkhorst R

    更新日期：2000-03-01 00:00:00

  • Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough.

    abstract：BACKGROUND:It remains uncertain why immunocompetent patients with bacterial community-acquired pneumonia (CAP) die, in spite of adequate antibiotics. METHODS:This is a secondary analysis of the CAPUCI database which was a prospective observational multicentre study. Two hundred and twelve immunocompetent patients admi...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-008-1363-6

    authors： Rodriguez A,Lisboa T,Blot S,Martin-Loeches I,Solé-Violan J,De Mendoza D,Rello J,Community-Acquired Pneumonia Intensive Care Units (CAPUCI) Study Investigators.

    更新日期：2009-03-01 00:00:00

  • Regional tidal ventilation and compliance during a stepwise vital capacity manoeuvre.

    abstract：PURPOSE:To determine whether, during mechanical ventilation, an optimal positive end-expiratory pressure (PEEP) can be identified by measurement of regional tidal volume and compliance [V (T(reg)), C (RS(reg))]. METHODS:Sixteen anaesthetized intubated neonatal piglets underwent a stepwise vital capacity manoeuvre perf...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-010-1995-1

    authors： Dargaville PA,Rimensberger PC,Frerichs I

    更新日期：2010-11-01 00:00:00

  • An unusual drain in the pleural cavity: iatrogenic pneumothorax due to pulmonary misplacement of a nasogastric tube.

    abstract：: ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-018-5280-z

    authors： Stefani A,Ruggiero C,Aramini B,Scamporlino A

    更新日期：2018-12-01 00:00:00

  • Meta-regression analysis of high-frequency ventilation vs conventional ventilation in infant respiratory distress syndrome.

    abstract：OBJECTIVE:There is considerable heterogeneity among randomized trials comparing high-frequency ventilation (HFV) with conventional mechanical ventilation (CMV) in premature neonates with respiratory distress syndrome. We investigated what factors explained differences in outcome among these trials. DESIGN:Meta-regress...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,meta分析

    doi：10.1007/s00134-007-0545-y

    authors： Bollen CW,Uiterwaal CS,van Vught AJ

    更新日期：2007-04-01 00:00:00

  • What the patients say: A study of reactions to an intensive care unit.

    abstract：:One hundred consecutive patients were interviewed between the 3rd and 7th days, inclusive, of their discharge from an intensive care unit to a general ward. The patients' recall of events related to their admission to the ICU was generally poor, and 41% of them felt that they had been confused at some time during thei...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01686054

    authors： Jones J,Hoggart B,Withey J,Donaghue K,Ellis BW

    更新日期：1979-05-01 00:00:00

  • Differential ventilation in unilateral lung disease: effects on respiratory mechanics and gas exchange.

    abstract：:Conventional PEEP ventilation has been recently reported to be deleterious in some cases of ARF with unilateral pneumonia. In such respect, two cases of unilateral bacterial pneumonia were intubated with a Carlens tracheal tube. Measurement of tidal volume, static compliance, and functional residual capacity of each l...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01683935

    authors： Rivara D,Bourgain JL,Rieuf P,Harf A,Lemaire F

    更新日期：1979-11-01 00:00:00

  • Inappropriate ventilator triggering caused by an in-line suction catheter.

    abstract：OBJECTIVE:To examine the phenomenon of inappropriate triggering caused by an in-line suction catheter. DESIGN:We used a test lung to assess inappropriate triggering in four ventilators with both pressure and flow triggering. RESULTS:With pressure triggering, inappropriate triggering occurred only in the presence of P...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-002-1239-0

    authors： Al-Khafaji A,Manning HL

    更新日期：2002-04-01 00:00:00

  • Volumetric capnography as a bedside monitoring of thrombolysis in major pulmonary embolism.

    abstract：OBJECTIVE:To describe the use of volumetric capnography, a plot of expired CO(2) concentration against expired volume, in monitoring fibrinolytic treatment of major pulmonary embolism. DESIGN AND SETTING:Two case reports in the emergency department of a teaching hospital. PATIENTS:Two conscious and spontaneously brea...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-004-2444-9

    authors： Verschuren F,Heinonen E,Clause D,Roeseler J,Thys F,Meert P,Marion E,El Gariani A,Col J,Reynaert M,Liistro G

    更新日期：2004-11-01 00:00:00

  • Increased RNA editing in children with cyanotic congenital heart disease.

    abstract：PURPOSE:To test the hypothesis that RNA editing is altered in pediatric patients with cyanotic congenital heart disease (CHD) and to determine whether A-to-I RNA editing is associated with the postoperative course following cardiac surgery. Cyanotic CHD is associated with a unique pathophysiology caused by chronic hypo...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-011-2296-z

    authors： Borik S,Simon AJ,Nevo-Caspi Y,Mishali D,Amariglio N,Rechavi G,Paret G

    更新日期：2011-10-01 00:00:00

  • Acute effects of continuous rotational therapy on ventilation-perfusion inequality in lung injury.

    abstract：OBJECTIVE:To investigate ventilation-perfusion (VA/Q) relationships, during continuous axial rotation and in the supine position, in patients with acute lung injury (ALI) using the multiple inert gas elimination technique. DESIGN:Prospective investigation. SETTING:Eighteen-bed intensive care unit in a university hosp...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340050534

    authors： Bein T,Reber A,Metz C,Jauch KW,Hedenstierna G

    更新日期：1998-02-01 00:00:00

  • High-mobility group box 1 protein plasma concentrations during septic shock.

    abstract：OBJECTIVE:To investigate plasma high-mobility group box 1 protein (HMGB1) concentration and its relationship with organ dysfunction and outcome in septic shock patients. DESIGN AND SETTING:Prospective, noninterventional study. Medical adult intensive care unit at a university hospital in France. PATIENTS:42 criticall...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-007-0691-2

    authors： Gibot S,Massin F,Cravoisy A,Barraud D,Nace L,Levy B,Bollaert PE

    更新日期：2007-08-01 00:00:00

  • Calpain I inhibitor ameliorates the indices of disease severity in a murine model of cerulein-induced acute pancreatitis.

    abstract：OBJECTIVE:Nuclear factor-kappaB (NF-kappaB) is a transcription factor which plays a pivotal role in the induction of genes involved in the response to injury and inflammation. Calpain I inhibitor is a potent antioxidant which is an effective inhibitor of NF-kappaB. This study examined whether the postulate that calpain...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-004-2328-z

    authors： Virlos I,Mazzon E,Serraino I,Genovese T,Di Paola R,Thiemerman C,Siriwardena A,Cuzzocrea S

    更新日期：2004-08-01 00:00:00

  • Fibrinolytic changes in a patient with toxic shock syndrome; release of active u-PA.

    abstract：OBJECTIVE:Definition of the changes in the activators of plasminogen, u-PA and t-PA, and examination of the possible generation of plasmin in the circulation in overwhelming sepsis. DESIGN:Serial blood analysis starting 4 h after development of symptoms of toxic shock syndrome. SETTING:Intensive care unit. PATIENT:A...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340050561

    authors： Haj MA,Robbie LA,Croll A,Adey GD,Bennett B

    更新日期：1998-03-01 00:00:00

  • The main determinants of nitrogen balance during total parenteral nutrition in critically ill injured patients.

    abstract：:Factors influencing nitrogen balance during total parenteral nutrition have been investigated in 34 critically ill injured patients studied during the first 6 days after trauma. Basal nitrogen balance was severely negative (-0.26 +/- 0.12 (SD) g X kg-1), but improved consistently during treatment. Nitrogen intake prov...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF00256262

    authors： Iapichino G,Radrizzani D,Solca M,Pesenti A,Gattinoni L,Ferro A,Leoni L,Langer M,Vesconi S,Damia G

    更新日期：1984-01-01 00:00:00

  • Closed system endotracheal suctioning maintains lung volume during volume-controlled mechanical ventilation.

    abstract：OBJECTIVE:A closed suction system (CS) maintains connection with the mechanical ventilator during tracheal suctioning and is claimed to limit loss in lung volume and oxygenation. We compared changes in lung volume, oxygenation, airway pressure and hemodynamics during endotracheal suctioning performed with CS and with a...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/s001340100897

    authors： Cereda M,Villa F,Colombo E,Greco G,Nacoti M,Pesenti A

    更新日期：2001-04-01 00:00:00

  • Candida spp. airway colonization could promote antibiotic-resistant bacteria selection in patients with suspected ventilator-associated pneumonia.

    abstract：OBJECTIVE:Candida spp. airway colonization could promote development of ventilator-associated pneumonia (VAP) caused by Pseudomonas aeruginosa, a potentially multidrug-resistant (MDR) bacteria, and worsen the outcome of VAP regardless of pathogen. We therefore address the question of the risk of MDR bacteria isolation ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-012-2584-2

    authors： Hamet M,Pavon A,Dalle F,Pechinot A,Prin S,Quenot JP,Charles PE

    更新日期：2012-08-01 00:00:00

  • Control of an epidemic spread of a multi-resistant strain of Acinetobacter calcoaceticus in a hospital.

    abstract：:The spread of a multi-resistant glucose-acidifying Acinetobacter calcoaceticus strain in a community hospital was studied. After admission of a colonized patient to the hospital the strain was found in clinical specimens from ICU patients and subsequently from several of these patients after transfer to medical wards....

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01058568

    authors： Crombach WH,Dijkshoorn L,van Noort-Klaassen M,Niessen J,van Knippenberg-Gordebeke G

    更新日期：1989-01-01 00:00:00

  • Variability in the concentrations of intravenous drug infusions prepared in a critical care unit.

    abstract：OBJECTIVE:To quantify the variability in the concentration of drug infusions prepared on an intensive care unit and establish whether there was a relationship between the quality of syringe labeling and drug preparation. DESIGN:Audit carried out over 3 weeks in May 2006 and completed in May 2007. SETTING:The adult ne...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-008-1113-9

    authors： Wheeler DW,Degnan BA,Sehmi JS,Burnstein RM,Menon DK,Gupta AK

    更新日期：2008-08-01 00:00:00

  • Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock.

    abstract：OBJECTIVE:The immediate overwhelming release of inflammatory mediators in septic shock is rapidly followed by strong anti-inflammatory responses inducing a state of immunosuppression. The patients who survive the initial hyper-inflammatory step of septic shock but subsequently die may be those who do not recover from i...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-006-0204-8

    authors： Monneret G,Lepape A,Voirin N,Bohé J,Venet F,Debard AL,Thizy H,Bienvenu J,Gueyffier F,Vanhems P

    更新日期：2006-08-01 00:00:00

  • Influence of SIMV plus inspiratory pressure support on VA/Q distributions during postoperative weaning.

    abstract：:Since the introduction of synchronized intermittent mandatory ventilation (SIMV) several advantages have been attributed to this ventilatory mode, one of them being a more homogeneous distribution of ventilation and perfusion than during controlled mechanical ventilation (CMV). Up to now no data are available to confi...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01704716

    authors： Santak B,Radermacher P,Sandmann W,Falke KJ

    更新日期：1991-01-01 00:00:00

  • Prolonged severe hypercapnia complicating near fatal asthma in a 35-year-old woman.

    abstract：OBJECTIVE:We describe a patient with a prolonged and severe hypercapnia occurring during an episode of status asthmaticus induced by ophthalmic instillation of carteolol. SETTING:Prehospital Emergency Medical Service and Pulmonary Intensive Care Unit in a university hospital. PATIENT:A 35-year-old female developed an...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340050772

    authors： Adnet F,Plaisance P,Borron SW,Levy A,Payen D

    更新日期：1998-12-01 00:00:00

  • Intravenous sildenafil for postoperative pulmonary hypertension in children with congenital heart disease.

    abstract：PURPOSE:To evaluate the efficacy and safety of intravenous sildenafil for immediate postoperative pulmonary hypertension (PH) in pediatric patients undergoing congenital heart surgery. METHODS:A double-blind, multicenter, placebo-controlled, dose-ranging, parallel-group trial was conducted. Patients were randomized to...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1007/s00134-010-2065-4

    authors： Fraisse A,Butrous G,Taylor MB,Oakes M,Dilleen M,Wessel DL

    更新日期：2011-03-01 00:00:00

  • Critical incidents related to invasive mechanical ventilation in the ICU: preliminary descriptive study.

    abstract：OBJECTIVES:To establish a preliminary list of critical incidents (CIs) associated with mechanical ventilation and to describe a CI reporting method. DESIGN:A list of CIs was established based on a consensus among ICU caregivers. The list was compared to CIs collected prospectively during a predefined study period. SE...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/s00134-002-1251-4

    authors： Auriant I,Reignier J,Pibarot ML,Bachat S,Tenaillon A,Raphael JC

    更新日期：2002-04-01 00:00:00

  • Slow moderate pressure recruitment maneuver minimizes negative circulatory and lung mechanic side effects: evaluation of recruitment maneuvers using electric impedance tomography.

    abstract：OBJECTIVE:To evaluate the efficacy of different lung recruitment maneuvers using electric impedance tomography. DESIGN AND SETTING:Experimental study in animal model of acute lung injury in an animal research laboratory. SUBJECTS:Fourteen pigs with saline lavage induced lung injury. INTERVENTIONS:Lung volume, region...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-005-2799-6

    authors： Odenstedt H,Lindgren S,Olegård C,Erlandsson K,Lethvall S,Aneman A,Stenqvist O,Lundin S

    更新日期：2005-12-01 00:00:00

  • Primary excision and immediate wound closure.

    abstract：:Surgical principles of early excision of devitalized tissue and prompt wound closure which govern the management of all traumatic injuries have been developed in the primary treatment of burns. Topical and systemic antibodies which delay wound infection and control invasive sepsis provide an initial period of two to t...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/BF01687263

    authors： Quinby WC Jr,Burke JF,Bondoc CC

    更新日期：1981-01-01 00:00:00