Differential ventilation in unilateral lung disease: effects on respiratory mechanics and gas exchange.

abstract：OBJECTIVE:a) to describe a non-barotraumatic ventilatory setting for independent lung ventilation (ILV); b) to determine the utility of single lung end-tidal CO(2) (EtCO(2)) monitoring to evaluate the ventilation to perfusion (V/Q) matching in each lung during ILV and for ILV weaning. DESIGN:prospective study. SETTIN...

journal_title：Intensive care medicine

authors： Cinnella G,Dambrosio M,Brienza N,Giuliani R,Bruno F,Fiore T,Brienza A

更新日期：2001-12-01 00:00:00

abstract：:We report the intensive care management of 23 children (age 3-15 years) following orthotopic heart (HT) and combined heart and lung transplantation (HLT) performed at our 2 institutes between February 1985 and August 1989. Cyclosporin A, azathioprine and steroids were given as routine immunosuppression, whilst anti-th...

journal_title：Intensive care medicine

authors： Whitehead B,James I,Helms P,Scott JP,Smyth R,Higenbottam TW,McGoldrick J,English TA,Wallwork J,Elliott M

更新日期：1990-01-01 00:00:00

abstract：:The treatment of severe tetanus with autonomic dysfunction is discussed, with emphasis on the use of magnesium sulphate. An exemplary case is reported, describing the inadequate response to magnesium, but the previously unreported and successful use of clonidine to control sympathetic overactivity. The properties of c...

journal_title：Intensive care medicine

authors： Sutton DN,Tremlett MR,Woodcock TE,Nielsen MS

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To determine whether, during mechanical ventilation, an optimal positive end-expiratory pressure (PEEP) can be identified by measurement of regional tidal volume and compliance [V (T(reg)), C (RS(reg))]. METHODS:Sixteen anaesthetized intubated neonatal piglets underwent a stepwise vital capacity manoeuvre perf...

journal_title：Intensive care medicine

authors： Dargaville PA,Rimensberger PC,Frerichs I

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVES:To study the pattern of lung emptying and expiratory resistance in mechanically ventilated patients with chronic obstructive pulmonary disease (COPD). DESIGN:A prospective physiological study. SETTING:A 12-bed Intensive Care Unit. PATIENTS:Ten patients with acute exacerbation of COPD. INTERVENTIONS:At th...

journal_title：Intensive care medicine

authors： Kondili E,Alexopoulou C,Prinianakis G,Xirouchaki N,Georgopoulos D

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:We propose that higher airway occlusion pressure (P0.1) responses to hypercapnic challenge (HC) indicate less severe injury. The study aim was to determine whether P0.1 responses to HC were associated with successful weaning after prolonged mechanical ventilation (PMV) in patients with brainstem lesions and t...

journal_title：Intensive care medicine

authors： Wu YK,Lee CH,Shia BC,Tsai YH,Tsao TC

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To determine the relationship between ionized calcium concentrations and blood lactate levels during cardiac arrest and cardiopulmonary resuscitation (CPR). DESIGN:A prospective cohort study. SETTING:Emergency department (ED) and general intensive care unit in a city hospital (tertiary care center). PATIEN...

journal_title：Intensive care medicine

authors： Gando S,Igarashi M,Kameue T,Nanzaki S

更新日期：1997-12-01 00:00:00

abstract：:The goals of management of patients with respiratory failure include improving arterial oxygenation with PEEP and red cell transfusion to maintain oxygen carrying capacity, both of which contribute to improving tissue oxygen delivery. However, standard CPD-stored blood is rapidly depleted of 2,3 diphosphoglycerate (2,...

journal_title：Intensive care medicine

authors： Kahn RC,Zaroulis C,Goetz W,Howland WS

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to identify risk factors and to describe epidemiological patterns for early-(EOB) and late-onset bacteremias (LOB) after trauma. DESIGN:A prospective study conducted on 141 consecutive trauma patients. SETTING:A general intensive care unit (ICU) of a university hospital. PATIENTS:...

journal_title：Intensive care medicine

authors： Antonelli M,Moro ML,D'Errico RR,Conti G,Bufi M,Gasparetto A

更新日期：1996-08-01 00:00:00

abstract：:Helicobacter pylori is estimated to infect over 50% of the world's population, the majority of whom are asymptomatic. Although most research to date has focused on local gastroduodenal disease manifestations, the potential impact of H. pylori infection and the associated chronic active inflammation on systemic disease...

journal_title：Intensive care medicine

authors： Robertson MS,Clancy RL,Cade JF

更新日期：2003-11-01 00:00:00

abstract：:Although colitis is often seen in critically all patients who have received multiple broad-spectrum antibiotics, there are no reports describing severe sepsis as a result of Clostridium difficile infection. We describe three cases of severe sepsis with local intestinal Clostridium difficile infection as the only ident...

journal_title：Intensive care medicine

authors： Lowenkron SE,Waxner J,Khullar P,Ilowite JS,Niederman MS,Fein AM

更新日期：1996-09-01 00:00:00

abstract：PURPOSE:To describe the course of early organ dysfunction in a cohort of patients admitted in ICU suffering classic heatstroke. METHODS:Prospective observational single-centre cohort study with a 1-year follow-up. INTERVENTIONS:None. MEASUREMENTS AND MAIN RESULTS:Clinical and biological data of 22 patients were anal...

journal_title：Intensive care medicine

authors： Pease S,Bouadma L,Kermarrec N,Schortgen F,Régnier B,Wolff M

更新日期：2009-08-01 00:00:00

abstract：:The measurement of functional residual capacity (FRC) has assumed new importance in the diagnosis of acute respiratory failure. However few reference values exist for FRC in supine positions for both sexes. We measured the FRC in 100 healthy subjects with the helium dilution closed circuit method in the sitting and su...

journal_title：Intensive care medicine

authors： Ibañez J,Raurich JM

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:Chronic pulmonary hypertension (PH) therapy is poorly investigated in intensive care. Our aim was to evaluate haemodynamic and neuroendocrine effects of the dual endothelin-1 (ET-1) blocker tezosentan in monocrotaline (MCT)-induced PH. METHODS:Male Wistar rats (180-200 g, n = 194) randomly received 60 mg kg(-1...

journal_title：Intensive care medicine

authors： Lourenço AP,Vasques-Nóvoa F,Oliveira-Pinto J,Fontoura D,Roncon-Albuquerque R Jr,Leite-Moreira AF

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:Acute kidney injury (AKI) frequently occurs after heart transplantation (HTx), but its relation to preoperative right heart hemodynamic (RHH) parameters remains unknown. Therefore, we aimed to determine their predictive properties for postoperative AKI severity within 30 days after HTx. METHODS:From 1984 to 20...

journal_title：Intensive care medicine

authors： Guven G,Brankovic M,Constantinescu AA,Brugts JJ,Hesselink DA,Akin S,Struijs A,Birim O,Ince C,Manintveld OC,Caliskan K

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:This study was undertaken to determine the delay of extubation attributable to ventilator-associated pneumonia (VAP) in comparison to other complications and complexity of surgery after repair of congenital heart lesions in neonates and children. METHODS:Cohort study in a pediatric intensive care unit of a t...

journal_title：Intensive care medicine

authors： Fischer JE,Allen P,Fanconi S

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:To study whether transient hyperglycemia adversely affects cerebral energy metabolism in patients with severe traumatic brain lesions. DESIGN AND SETTING:Prospective, nonrandomized study in the neurosurgical intensive care unit of a university hospital. PATIENTS:108 patients treated for severe traumatic bra...

journal_title：Intensive care medicine

authors： Diaz-Parejo P,Ståhl N,Xu W,Reinstrup P,Ungerstedt U,Nordström CH

更新日期：2003-04-01 00:00:00

abstract：PURPOSE:Fluid overload is a risk factor for poor outcome in intensive care; thus volume loading should be tailored towards patients who are likely to increase stroke volume. We aimed to evaluate the paediatric predictive ability (stroke volume increase of at least 15 % after fluid bolus) of novel and established volume...

journal_title：Intensive care medicine

authors： Saxena R,Durward A,Steeley S,Murdoch IA,Tibby SM

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The systemic inflammatory response syndrome (SIRS) may be triggered by endotoxin. Humans have antibodies directed against the core of endotoxin (endotoxin core antibodies, EndoCAb) that appear to be protective following surgery and in sepsis. We hypothesised that children with elevated antibodies to endotoxi...

journal_title：Intensive care medicine

authors： Stephens RCM,Fidler K,Wilson P,Barclay GR,Mythen MG,Dixon GLJ,Turner MW,Klein NJ,Peters MJ

更新日期：2006-02-01 00:00:00

abstract：:We report a clinical observation of acute pancreatitis due to severe hypertriglyceridemia in a pregnant woman. In order to decrease the serum triglyceride level rapidly, two lipaphereses were undertaken using the double-filtration technique. This lipoprotein apheresis technique is briefly described and the efficacy in...

journal_title：Intensive care medicine

authors： Achard JM,Westeel PF,Moriniere P,Lalau JD,de Cagny B,Fournier A

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:In patients with severe sepsis, no randomized clinical trial has tested the concept of de-escalation of empirical antimicrobial therapy. This study aimed to compare the de-escalation strategy with the continuation of an appropriate empirical treatment in those patients. METHODS:This was a multicenter non-bl...

journal_title：Intensive care medicine

authors： Leone M,Bechis C,Baumstarck K,Lefrant JY,Albanèse J,Jaber S,Lepape A,Constantin JM,Papazian L,Bruder N,Allaouchiche B,Bézulier K,Antonini F,Textoris J,Martin C,AZUREA Network Investigators.

更新日期：2014-10-01 00:00:00

abstract：PURPOSE:To determine whether erythromycin is non-inferior to metoclopramide in facilitating post-pyloric placement of self-propelled spiral nasoenteric tubes (NETs) in critically ill patients. METHODS:A prospective, multicenter, open-label, parallel, and non-inferiority randomized controlled trial was conducted compar...

journal_title：Intensive care medicine

authors： Hu B,Ouyang X,Lei L,Sun C,Chi R,Guo J,Guo W,Zhang Y,Li Y,Huang D,Sun H,Nie Z,Yu J,Zhou Y,Wang H,Zhang J,Chen C

更新日期：2018-12-01 00:00:00

abstract：PURPOSE:Critical care ultrasonography has utility for the diagnosis and management of critical illness and is in widespread use by frontline intensivists. As there is a need for research to validate and extend its utility, the Editor of Intensive Care Medicine included critical care ultrasonography as a topic in the IC...

journal_title：Intensive care medicine

authors： Mayo P,Arntfield R,Balik M,Kory P,Mathis G,Schmidt G,Slama M,Volpicelli G,Xirouchaki N,McLean A,Vieillard-Baron A

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:Extracorporeal life support (ECLS) is used for patients with refractory heart failure with or without respiratory failure. This temporary support is provided by blood pumps which are connected to large vessels. Bleeding episodes are a typical complication in patients with ECLS. Recently, several studies illustr...

journal_title：Intensive care medicine

authors： Heilmann C,Geisen U,Beyersdorf F,Nakamura L,Benk C,Trummer G,Berchtold-Herz M,Schlensak C,Zieger B

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To investigate the accuracy of eight different prognostic scores (Stiehm, Niklasson, Leclerc, Garlund, the MOC score, Tesero, the Glasgow Meningococcal Septicaemia Prognostic Score (GMSPS) and Tüyzüs) in the prediction of fatal outcome in meningococcal disease. DESIGN:Combined prospective and retrospective s...

journal_title：Intensive care medicine

authors： Derkx HH,van den Hoek J,Redekop WK,Bijlmer RP,van Deventer SJ,Bossuyt PM

更新日期：1996-12-01 00:00:00

abstract：:This narrative review focuses on thoracic ultrasonography (lung and pleural) with the aim of outlining its utility for the critical care clinician. The article summarizes the applications of thoracic ultrasonography for the evaluation and management of pneumothorax, pleural effusion, acute dyspnea, pulmonary edema, pu...

journal_title：Intensive care medicine

authors： Mayo PH,Copetti R,Feller-Kopman D,Mathis G,Maury E,Mongodi S,Mojoli F,Volpicelli G,Zanobetti M

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To characterize the perceived utilization of physical restraint (PR) in mechanically ventilated intensive care unit (ICU) patients and to identify clinical and structural factors influencing PR use. METHODS:A questionnaire was personally handed to one intensivist in 130 ICUs in France then collected on-site 2 ...

journal_title：Intensive care medicine

authors： De Jonghe B,Constantin JM,Chanques G,Capdevila X,Lefrant JY,Outin H,Mantz J,Group Interfaces Sédation.

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Candida spp. airway colonization could promote development of ventilator-associated pneumonia (VAP) caused by Pseudomonas aeruginosa, a potentially multidrug-resistant (MDR) bacteria, and worsen the outcome of VAP regardless of pathogen. We therefore address the question of the risk of MDR bacteria isolation ...

journal_title：Intensive care medicine

authors： Hamet M,Pavon A,Dalle F,Pechinot A,Prin S,Quenot JP,Charles PE

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:Reporting neurodevelopmental outcome of 8-year-old children treated with neonatal extracorporeal membrane oxygenation (ECMO). METHODS:In a follow-up study in 135 8-year-old children who received neonatal ECMO between 1996 and 2001 we assessed intelligence (Revised Amsterdam Intelligence Test), concentration (B...

journal_title：Intensive care medicine

authors： Madderom MJ,Reuser JJ,Utens EM,van Rosmalen J,Raets M,Govaert P,Steiner K,Gischler SJ,Tibboel D,van Heijst AF,Ijsselstijn H

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVES:To investigate at what time the peak level should be determined under conventional thrice daily (t.i.d.) administration of the aminoglycoside netilmicin and to study its serum concentrations under once daily (od) treatment to define the required daily dose and to gain information about convenient drug monito...

journal_title：Intensive care medicine

authors： Konrad F,Wagner R,Neumeister B,Rommel H,Georgieff M

更新日期：1993-01-01 00:00:00