Craniectomy in severe, life-threatening encephalitis: a report on outcome and long-term prognosis of four cases.

abstract：:Risk of critical illness is determined both by genetic and environmental influences, particularly those relating to infectious and cardiovascular diseases. Physiologically-based scoring systems cannot measure prior risk because they do not quantify physiological reserve independently of the acute illness. Genetic prof...

journal_title：Intensive care medicine

authors： Bion JF

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To determine the steady-state plasma and epithelial lining fluid (ELF) concentrations of ceftazidime administered in continuous infusion to critically ill patients with severe nosocomial pneumonia. DESIGN:Prospective, open-label study. SETTING:An intensive care unit and research ward in a university hospita...

journal_title：Intensive care medicine

authors： Boselli E,Breilh D,Rimmelé T,Poupelin JC,Saux MC,Chassard D,Allaouchiche B

更新日期：2004-05-01 00:00:00

abstract：INTRODUCTION:Microcirculatory abnormalities are frequently observed in patients with severe heart failure and correlate to worse outcomes. We tested the hypothesis that nitroglycerin dose-dependently improves perfusion in severe heart failure and that this could be monitored by measuring central-peripheral temperature ...

journal_title：Intensive care medicine

authors： den Uil CA,Caliskan K,Lagrand WK,van der Ent M,Jewbali LS,van Kuijk JP,Spronk PE,Simoons ML

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVES:Critically ill patients often develop anaemia which can be related to a number of factors. However, the exact causes of anaemia in many patients remain unexplained. We hypothesized that the relationship between erythropoietin (EPO) and haematocrit may be altered in critically ill patients. DESIGN:Serum conc...

journal_title：Intensive care medicine

authors： Rogiers P,Zhang H,Leeman M,Nagler J,Neels H,Mélot C,Vincent JL

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:The aim of this prospective study was to evaluate the value of sinus echography results to directly indicate a transnasal puncture in intubated patients with suspicion of nosocomial maxillary sinusitis. DESIGN:prospective clinical investigation. SETTING:medical intensive care unit. PATIENTS:sixty patients ...

journal_title：Intensive care medicine

authors： Vargas F,Bui HN,Boyer A,Bébear CM,Lacher-Fougére S,De-Barbeyrac BM,Salmi LR,Traissac L,Gbikpi-Benissan G,Gruson D,Hilbert G

更新日期：2006-06-01 00:00:00

abstract：:The process of surgical decision making is based on both general principles that are amenable to evaluation using rigorous techniques of clinical research and the intangible element of surgical judgment that seeks to apply those principles to the care of an individual patient. The role of surgical judgment is inescapa...

journal_title：Intensive care medicine

authors： Jimenez MF,Marshall JC,International Sepsis Forum.

更新日期：2001-01-01 00:00:00

abstract：:A 46-year-old man was diagnosed clinically brain dead after sustaining head trauma. The patient was in deep coma, brain nerves were unresponsive and spontaneous breathing was absent. However, EEG showed well preserved activity, but no reactivity to external stimuli. EEG activity disappeared within 40 h. BAEP were high...

journal_title：Intensive care medicine

authors： Kaukinen S,Mäkelä K,Häkkinen VK,Martikainen K

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:After resuscitation, asphyxiated neonates often develop poor cardiac function with hypotension, pulmonary hypertension and multiorgan ischemia. In a swine model of neonatal hypoxia-reoxygenation, effects of epinephrine, dobutamine and milrinone on systemic, pulmonary and regional hemodynamics and oxygen tran...

journal_title：Intensive care medicine

authors： Joynt C,Bigam DL,Charrois G,Jewell LD,Korbutt G,Cheung PY

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:Hypoxic hepatitis (HH) is a form of hepatic injury following arterial hypoxemia, ischemia, and passive congestion of the liver. We investigated the incidence and the prognostic implications of HH in the medical intensive care unit (ICU). METHODS:A total of 1,066 consecutive ICU admissions at three medical ICUs...

journal_title：Intensive care medicine

authors： Fuhrmann V,Kneidinger N,Herkner H,Heinz G,Nikfardjam M,Bojic A,Schellongowski P,Angermayr B,Schöniger-Hekele M,Madl C,Schenk P

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Ornithine alpha-ketoglutarate (OKG) has proved to be efficient in restoring glutamine (Gln) pools which are strongly depleted in hypercatabolic patients. Since its two components, alpha-ketoglutarate (alphaKG) and ornithine (Orn), give rise to glutamate (Glu), they are both considered as Gln precursors. The ...

journal_title：Intensive care medicine

authors： Cynober L,Lasnier E,Le Boucher J,Jardel A,Coudray-Lucas C

更新日期：2007-03-01 00:00:00

abstract：:Nosocomial pneumonia continues to represent a significant cause of morbidity and mortality in hospitalized patients. Bacteria are responsible for greater than 90% of the pneumonias, the most common isolates being aerobic Gram-negative bacilli and S. aureus. Cornerstones of treatment are intravenous antibiotics and sup...

journal_title：Intensive care medicine

authors： Unertl KE,Lenhart FP,Forst H,Peter K

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:In critically ill pediatric patients, fluid overload (FO) >10% has been identified as a threshold for possible interventions, including initiation of continuous renal replacement therapy (CRRT). However, multiple definitions have been reported, and there remains no consensus method for FO calculation. The goal ...

journal_title：Intensive care medicine

authors： Lombel RM,Kommareddi M,Mottes T,Selewski DT,Han YY,Gipson DS,Collins KL,Heung M

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of two different comorbidity measures on the 6-month mortality of severely ill cancer patients. DESIGN AND SETTING:Prospective cohort study in a ten-bed oncological medical-surgical intensive care unit (ICU). PATIENTS:A total of 772 consecutive patients were included over a 45-month p...

journal_title：Intensive care medicine

authors： Soares M,Salluh JI,Ferreira CG,Luiz RR,Spector N,Rocco JR

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:Hypoxia-ischemia (HI), as a major cause of fetal brain damage, has long-lasting neurological implications. Therefore, therapeutic interventions that attenuate the neuropathological outcome of HI while also improving the neurofunctional outcome are of paramount clinical importance. The aim of this study was to i...

journal_title：Intensive care medicine

authors： Fathali N,Lekic T,Zhang JH,Tang J

更新日期：2010-09-01 00:00:00

abstract：:Membranous laryngotracheobronchitis is a very serious infection which affects the larynx, trachea and bronchi, requiring aggressive therapeutic measures. It has been recently rediscovered as a cause of disease in children. However, it is a very unusual complication of measles. Two infants with measles and membranous l...

journal_title：Intensive care medicine

authors： Labay MV,Ramos R,Hervas JA,Reynes J,Gomez B

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:Definition of the changes in the activators of plasminogen, u-PA and t-PA, and examination of the possible generation of plasmin in the circulation in overwhelming sepsis. DESIGN:Serial blood analysis starting 4 h after development of symptoms of toxic shock syndrome. SETTING:Intensive care unit. PATIENT:A...

journal_title：Intensive care medicine

authors： Haj MA,Robbie LA,Croll A,Adey GD,Bennett B

更新日期：1998-03-01 00:00:00

abstract：:The spread of a multi-resistant glucose-acidifying Acinetobacter calcoaceticus strain in a community hospital was studied. After admission of a colonized patient to the hospital the strain was found in clinical specimens from ICU patients and subsequently from several of these patients after transfer to medical wards....

journal_title：Intensive care medicine

authors： Crombach WH,Dijkshoorn L,van Noort-Klaassen M,Niessen J,van Knippenberg-Gordebeke G

更新日期：1989-01-01 00:00:00

abstract：:Fifteen polytrauma patients with asymmetric pulmonary contusion were treated with differential lung ventilation (DLV) for a mean of 106 hours (range 24-298, median 83). The differential time constant (Tc), compliance (Ct), inspiratory and expiratory airway resistance (Rawinsp, Rawexp) and peak-airway pressure (Pawpeak...

journal_title：Intensive care medicine

authors： Zandstra DF,Stoutenbeek CP,Bams JL

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:To describe a real-time ultrasound sign, the visualization of the cavity and the walls of the maxillary sinus ("sinusogram"), and to assess its correlation with total opacity of the sinus. DESIGN:Prospective clinical study. SETTING:The medical ICU of a university-affiliated hospital. PATIENTS:The significa...

journal_title：Intensive care medicine

authors： Lichtenstein D,Biderman P,Mezière G,Gepner A

更新日期：1998-10-01 00:00:00

abstract：INTRODUCTION:The emphasis on the importance of professionalism in a recent CoBaTrICE-IT paper was impressive. However, insight into the elements of professionalism as perceived relevant for intensivists from the fellows' view, and how these are taught and learned, is limited. OBJECTIVES AND METHODS:A nationwide study ...

journal_title：Intensive care medicine

authors： van Mook WN,de Grave WS,Gorter SL,Muijtjens AM,Zwaveling JH,Schuwirth LW,van der Vleuten CP

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:The pressure-volume (P/V) curve has been proposed as a tool to adjust the ventilatory settings in cases of acute respiratory distress syndrome (ARDS). The aim of this study was to test the influence of P/V tracing methodology on the presence and value of the upper inflection point (UIP). METHODS:In 13 medica...

journal_title：Intensive care medicine

authors： Servillo G,De Robertis E,Maggiore S,Lemaire F,Brochard L,Tufano R

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To study the wishes of a sample of French patients about medical information and surrogacy, at a time when the French Ministry of Health is supporting increased patient autonomy. DESIGN:A cohort of competent patients with non-critical illnesses or injuries completed an intention-to-act questionnaire on the a...

journal_title：Intensive care medicine

authors： Roupie E,Santin A,Boulme R,Wartel JS,Lepage E,Lemaire F,Lejonc JL,Montagne O

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Cytokeratin 19 (CK19) is a specific cytoskeletal structure for alveolar epithelium. We hypothesized that the levels of CK19 fragments in bronchoalveolar lavage (BAL) fluid could serve as an index of epithelial injury and as a prognosis marker in patients with acute lung injury (ALI) or acute respiratory distr...

journal_title：Intensive care medicine

authors： Stern JB,Paugam C,Validire P,Adle-Biassette H,Jaffré S,Dehoux M,Crestani B

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To assess the attitudes of physicians in Milan, Italy, intensive care units (ICUs) regarding end-of-life decisions. DESIGN:Anonymous self-administered questionnaire. SETTING:All 20 ICUs in Milan. PARTICIPANTS:Physicians employed in the ICUs. MEASUREMENTS AND RESULTS:The response rate was 87% (225 of 259)....

journal_title：Intensive care medicine

authors： Giannini A,Pessina A,Tacchi EM

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To measure the effects of rapid permissive hypercapnia on hemodynamics and gas exchange in patients with acute respiratory distress syndrome (ARDS). DESIGN:Prospective study. SETTING:18-bed, medical intensive care unit, university hospital. PATIENTS:11 mechanically ventilated ARDS patients. INTERVENTION:P...

journal_title：Intensive care medicine

authors： Thorens JB,Jolliet P,Ritz M,Chevrolet JC

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of some acid-base abnormalities on blood capacity of transporting CO(2). DESIGN:Prospective study. SETTING:General and Cardiosurgical ICUs of a University hospital. PATIENTS:Six groups of ten patients characterized by: metabolic alkalosis; respiratory alkalosis; absence of acid-b...

journal_title：Intensive care medicine

authors： Cavaliere F,Antonelli M,Arcangeli A,Conti G,Pennisi MA,Proietti R

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:To clarify the risk of secondary exposure of medical staff to sarin vapor in the emergency room, and to warn emergency room staffs of the hazard. DESIGN:Retrospective observational survey. SETTING:Emergency department of a university hospital in a metropolitan area of Japan. PARTICIPANTS:Fifteen doctors tr...

journal_title：Intensive care medicine

authors： Nozaki H,Hori S,Shinozawa Y,Fujishima S,Takuma K,Sagoh M,Kimura H,Ohki T,Suzuki M,Aikawa N

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:To define the changes in middle cerebral artery flow velocity (Vmca) and the electroencephalogram (EEG) during rapid reduction in arterial carbon dioxide (PCO2) from acute hypercapnia. DESIGN. Human volunteer study. SETTING:University-affiliated hospital experimental laboratory. PARTICIPANTS:Nine healthy vo...

journal_title：Intensive care medicine

authors： Halpern P,Neufeld MY,Sade K,Silbiger A,Szold O,Bornstein NM,Sorkine P

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To analyze the effect of endothelin-1 on pulmonary arterial and venous contractile force in vitro and on up- and downstream pulmonary vascular resistance in vivo under sham and endotoxemic conditions in pigs. MATERIALS AND METHODS:In vitro: paired preparations of pulmonary arteries and veins were mounted in ...

journal_title：Intensive care medicine

authors： Rossi P,Persson B,Boels PJ,Arner A,Weitzberg E,Oldner A

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To study the pharmacokinetics and local tissue effects resulting from the intratracheal administration of preservative-free fentanyl. DESIGN:Prospective, randomized, blinded and controlled animal study. SETTING:University research laboratory. SUBJECTS:Eighteen adult male New Zealand rabbits. INTERVENTIONS...

journal_title：Intensive care medicine

authors： Irazuzta JE,Ahmed U,Gancayco A,Ahmed ST,Zhang J,Anand KJ

更新日期：1996-02-01 00:00:00