Long-term evaluation of granulocyte-colony stimulating factor on hypoxic-ischemic brain damage in infant rats.

abstract：OBJECTIVE:Blood O(2) saturation and lactate concentration gradients from superior vena cava (SVC) to pulmonary artery (PA) occur in critically ill patients. These gradients (DeltaSO(2) and Delta[Lac]) may be positive or negative. We tested the hypothesis that positive DeltaSO(2) and Delta[Lac] are associated with impro...

journal_title：Intensive care medicine

authors： Gutierrez G,Comignani P,Huespe L,Hurtado FJ,Dubin A,Jha V,Arzani Y,Lazzeri S,Sosa L,Riva J,Kohn W,Suarez D,Lacuesta G,Olmos D,Mizdraji C,Ojeda A

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:Sedatives administered to critically ill children should be titrated to effect, because both under- and oversedation may have negative effects. We conducted a systematic review to examine reported incidences of under-, optimal, and oversedation in critically ill children receiving intensive care. METHODS:A sys...

journal_title：Intensive care medicine

authors： Vet NJ,Ista E,de Wildt SN,van Dijk M,Tibboel D,de Hoog M

更新日期：2013-09-01 00:00:00

abstract：:Specific regulations regarding oversight of research in children vary from country to country, but most share common principles derived from major consensus documents. Whereas the permissibility of research on adults depends heavily upon the informed consent of the subject, the regulation of research in pediatrics is ...

journal_title：Intensive care medicine

authors： Truog RD

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:Controversy over the optimal intravenous fluid for volume resuscitation continues unabated. Our objectives were to characterize the demographics of physicians who prescribe intravenous colloids and determine factors that enter into their decision to choose a colloid. DESIGN:Questionnaire with 61 items. PAR...

journal_title：Intensive care medicine

authors： Miletin MS,Stewart TE,Norton PG

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the Datex Deltatrac II for measurements in neonates requiring mechanical ventilation. DESIGN:Prospective laboratory evaluation, using a ventilated lung model and gas injection. During simulation of 79 neonatal respiratory settings, assessment of oxygen consumption (VO2), carbon dioxide production...

journal_title：Intensive care medicine

authors： Behrends M,Kernbach M,Bräuer A,Braun U,Peters J,Weyland W

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:Inhalation of nitric oxide (NO) selectively dilates pulmonary vessels in well-ventilated regions. Prostaglandin F2 alpha (PGF2 alpha) is a vasoconstrictor and is reported to enhance hypoxic pulmonary vasoconstriction. The objective of this study was to examine whether the combination of intravenous PGF2 alph...

journal_title：Intensive care medicine

authors： Kobayashi H,Tanaka N,Winkler M,Zapol WM

更新日期：1996-07-01 00:00:00

abstract：:The use of induced hypertension in head injury patients is controversial. We present the case of a 19-year-old man admitted with severe head trauma after a road accident and describe the beneficial effects that increasing arterial blood pressure had on the cerebral perfusion pressure, cerebral blood flow and jugular b...

journal_title：Intensive care medicine

authors： Ferring M,Berré J,Vincent JL

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:The objective was to identify factors associated with thrombocytopenia and to assess to what extent thrombocytopenia increases bleeding complications in liver transplant patients. DESIGN:Retrospective study. SETTING:Surgical intensive care unit in a university hospital. PATIENTS:One hundred and sixty-one p...

journal_title：Intensive care medicine

authors： Ben Hamida C,Lauzet JY,Rézaiguia-Delclaux S,Duvoux C,Cherqui D,Duvaldestin P,Stéphan F

更新日期：2003-05-01 00:00:00

abstract：:The process of surgical decision making is based on both general principles that are amenable to evaluation using rigorous techniques of clinical research and the intangible element of surgical judgment that seeks to apply those principles to the care of an individual patient. The role of surgical judgment is inescapa...

journal_title：Intensive care medicine

authors： Jimenez MF,Marshall JC,International Sepsis Forum.

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:There are a number of potential etiologies of severe bleeding encountered in the intensive care unit. Although rare, acquired hemophilia is one such etiology that often presents with major bleeding requiring intensive care. Despite the introduction of effective treatments, the reported mortality rate of patie...

journal_title：Intensive care medicine

authors： Shander A,Walsh CE,Cromwell C

更新日期：2011-08-01 00:00:00

abstract：: ...

journal_title：Intensive care medicine

authors： Stefani A,Ruggiero C,Aramini B,Scamporlino A

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To assess the ability of the Clinical Risk Index for Babies (CRIB) to predict long-term neurodevelopmental impairment in very low birth weight (VLBW) infants. DESIGN:Single-center cohort study. SETTING:Tertiary neonatal care hospital and follow-up clinic. PATIENTS:Four hundred fifty-five VLBW infants conse...

journal_title：Intensive care medicine

authors： Bührer C,Grimmer I,Metze B,Obladen M

更新日期：2000-03-01 00:00:00

abstract：:Pneumonia caused by herpes simplex virus type 1 (HSV1) is rare and occurs in severely immunosuppressed patients. HSV1 can be detected in bronchoalveolar lavage (BAL) from patients presenting with respiratory failure, but its direct effect on disease is difficult to prove. We demonstrate the causative role of HSV1 in t...

journal_title：Intensive care medicine

authors： François-Dufresne A,Garbino J,Ricou B,Wunderli W

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:To determine the value of procalcitonin (PCT) in the early diagnosis (and differentiation) of patients with SIRS, sepsis, severe sepsis, and septic shock in comparison to C-reactive protein (CRP), white blood cell and thrombocyte count, and APACHE-II score (AP-II). DESIGN:Prospective cohort study including a...

journal_title：Intensive care medicine

authors： Brunkhorst FM,Wegscheider K,Forycki ZF,Brunkhorst R

更新日期：2000-03-01 00:00:00

abstract：:The Limulus amoebocyte lysate assay was used as one of a series of laboratory and clinical investigations on a group of 31 patients suffering from septic shock in order to assess the clinical significance of this assay for the detection of circulating endotoxin in clinical gram-negative sepsis. Four patients with card...

journal_title：Intensive care medicine

authors： McCartney AC,Banks JG,Clements GB,Sleigh JD,Tehrani M,Ledingham IM

更新日期：1983-01-01 00:00:00

abstract：:The purpose of this study was noninvasive assessment of respiratory compliance and resistance in mechanically ventilated patients with acute respiratory failure (ARF). To this end, flow, change in lung volume, and airway pressure were measured at the proximal tip of the endotracheal tubes in twenty nine critically ill...

journal_title：Intensive care medicine

authors： Bernasconi M,Ploysongsang Y,Gottfried SB,Milic-Emili J,Rossi A

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Vasopressors are administered to critically ill patients with vasodilatory shock not responsive to volume resuscitation, and less often in cardiogenic shock, and hypovolemic shock. OBJECTIVES:The objectives are to review safety and efficacy of vasopressors, pathophysiology, agents that decrease vasopressor ...

journal_title：Intensive care medicine

authors： Russell JA

更新日期：2019-11-01 00:00:00

abstract：:The treatment of severe tetanus with autonomic dysfunction is discussed, with emphasis on the use of magnesium sulphate. An exemplary case is reported, describing the inadequate response to magnesium, but the previously unreported and successful use of clonidine to control sympathetic overactivity. The properties of c...

journal_title：Intensive care medicine

authors： Sutton DN,Tremlett MR,Woodcock TE,Nielsen MS

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Current medical knowledge lacks specific information regarding creatine kinase (CK) elevation in influenza A pH1N1 (2009) infection. OBJECTIVES:Primary endpoints were correlation between CK at intensive care unit (ICU) admission and ICU mortality. Secondary endpoints were ICU length of stay (LOS), mechanica...

journal_title：Intensive care medicine

authors： Borgatta B,Pérez M,Rello J,Vidaur L,Lorente L,Socías L,Pozo JC,Pozo J,Garnacho-Montero J,Rello J,pH1N1 GTEI\/SEMICYUC.

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:We assessed feasibility and safety of extracorporeal carbon dioxide removal (ECCO2R) to facilitate ultra-protective ventilation (VT 4 mL/kg and PPLAT ≤ 25 cmH2O) in patients with moderate acute respiratory distress syndrome (ARDS). METHODS:Prospective multicenter international phase 2 study. Primary endpoint w...

journal_title：Intensive care medicine

authors： Combes A,Fanelli V,Pham T,Ranieri VM,European Society of Intensive Care Medicine Trials Group and the “Strategy of Ultra-Protective lung ventilation with Extracorporeal CO2 Removal for New-Onset moderate to severe ARDS” (SUPERNOVA) investigators

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:To assess the utility of two in situ techniques, differential time to positivity (DTP) and semiquantitative superficial cultures (SQSC) for diagnosing catheter-related bloodstream infection (CR-BSI) in critically ill adults. METHODS:This was a prospective cohort study in patients with suspected CR-BSI arising ...

journal_title：Intensive care medicine

authors： Gowardman JR,Jeffries P,Lassig-Smith M,Stuart J,Jarrett P,Deans R,McGrail M,George NM,Nimmo GR,Rickard CM

更新日期：2013-01-01 00:00:00

abstract：:Paediatric admissions to a general ITU are briefly reviewed. Although it may not be an ideal arrangement it is suggested that children can be safely cared for in such a unit. The problems created by the child with acute upper airway obstruction are discussed to demonstrate the way in which the unit is organized to rec...

journal_title：Intensive care medicine

authors： Eastham EJ,Papadatos J,Cook S,Stoddart JC

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To determine the incidence of Clostridium difficile (CD) diarrhoea in feed-intolerant, critically ill patients who received erythromycin-based prokinetic therapy. DESIGN AND SETTING:Prospective observational study in a mixed intensive care unit. METHODS:The development of diarrhoea (> 3 loose, liquid stool ...

journal_title：Intensive care medicine

authors： Nguyen NQ,Ching K,Fraser RJ,Chapman MJ,Holloway RH

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of respiratory physiotherapy on the prevention and treatment of ventilator-associated pneumonia (VAP) for adults in an intensive care unit (ICU) with an acquired brain injury (ABI). DESIGN AND SETTING:Two-part, prospective, randomised controlled trial. PATIENTS:A total of 144 subje...

journal_title：Intensive care medicine

authors： Patman S,Jenkins S,Stiller K

更新日期：2009-02-01 00:00:00

abstract：:The case of an 11-year-old boy who suffered second and third degree burns to 78% of his body is reported. The large doses of morphine used as analgesia resulted in severe side effects: ventilatory dependence, impairment of gastrointestinal function and psychological disturbance. Intravenous lignocaine was added withou...

journal_title：Intensive care medicine

authors： Lyons B,Casey W,Doherty P,McHugh M,Moore KP

更新日期：1996-03-01 00:00:00

abstract：PURPOSE:Septic shock induces a decrease in dendritic cells (DCs) that may contribute to sepsis-induced immunosuppression. We analyzed the time course of circulating DCs in patients with septic shock and its relation to susceptibility to intensive care unit (ICU)-acquired infections. METHODS:We enrolled adult patients ...

journal_title：Intensive care medicine

authors： Grimaldi D,Louis S,Pène F,Sirgo G,Rousseau C,Claessens YE,Vimeux L,Cariou A,Mira JP,Hosmalin A,Chiche JD

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:The aim of this prospective study was to evaluate the value of sinus echography results to directly indicate a transnasal puncture in intubated patients with suspicion of nosocomial maxillary sinusitis. DESIGN:prospective clinical investigation. SETTING:medical intensive care unit. PATIENTS:sixty patients ...

journal_title：Intensive care medicine

authors： Vargas F,Bui HN,Boyer A,Bébear CM,Lacher-Fougére S,De-Barbeyrac BM,Salmi LR,Traissac L,Gbikpi-Benissan G,Gruson D,Hilbert G

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that the rate of degradation of exogenously administered albumin is faster with bolus administration than with continuous infusion and thus that a bolus administration is less efficacious in restoring blood albumin concentration (BAC) in the hypoalbuminemic critically ill pediatric pati...

journal_title：Intensive care medicine

authors： Greissman A,Silver P,Nimkoff L,Sagy M

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:The Brugada syndrome is a clinical and electrocardiographic familial entity, which may lead to sudden cardiac death. A Brugada pattern ECG may occasionally be caused by conditions such as an overdose of tricyclic antidepressants (TCA). Toxicity of TCA frequently results in the need for critical care support. ...

journal_title：Intensive care medicine

authors： Monteban-Kooistra WE,van den Berg MP,Tulleken JE,Ligtenberg JJM,Meertens JHJM,Zijlstra JG

更新日期：2006-02-01 00:00:00

abstract：PURPOSE:We conducted a retrospective cohort study in an academic tertiary care center to characterize ventilator-associated pneumonia (VAP) in pediatric patients after cardiac surgery in The Netherlands. METHODS:All patients following cardiac surgery and mechanically ventilated for ≥24 h were included. The primary out...

journal_title：Intensive care medicine

authors： Roeleveld PP,Guijt D,Kuijper EJ,Hazekamp MG,de Wilde RB,de Jonge E

更新日期：2011-10-01 00:00:00