A comparative assessment of two conservative methods for the diagnosis of catheter-related infection in critically ill patients.

abstract：:A study was conducted to evaluate repeated intrathecal injections of baclofen, without artificial ventilation, in the treatment of severe tetanus. Ten patients, 5 men and 5 women, with a mean age of 34 +/- 7 years, were included in the study. The dose of baclofen injected was 1000 micrograms between the ages of 16 and...

journal_title：Intensive care medicine

authors： Saissy JM,Demazière J,Vitris M,Seck M,Marcoux L,Gaye M,Ndiaye M

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To investigate nasal nitric oxide (NO) excretion, pulmonary NO excretion, and autoinhalation of nasally released NO at rest compared with that during moderate exercise in smokers and non-smokers. DESIGN:Prospective observational study. SETTING:University laboratory. PARTICIPANTS:Fourteen healthy adult volu...

journal_title：Intensive care medicine

authors： Busch T,Kuhlen R,Knorr M,Kelly K,Lewandowski K,Rossaint R,Falke KJ,Gerlach H

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To determine if the plasma levels of three endothelial-specific proteins, von Willebrand factor (vWF), tissue factor pathway inhibitor (TFPI) and thrombomodulin (TM) may be useful in predicting the development of acute respiratory distress syndrome (ARDS). DESIGN:Blood samples were obtained from normal healt...

journal_title：Intensive care medicine

authors： Bajaj MS,Tricomi SM

更新日期：1999-11-01 00:00:00

abstract：PURPOSE:Ventricular-arterial (V-A) decoupling decreases myocardial efficiency and is exacerbated by tachycardia that increases static arterial elastance (Ea). We thus investigated the effects of heart rate (HR) reduction on Ea in septic shock patients using the beta-blocker esmolol. We hypothesized that esmolol improve...

journal_title：Intensive care medicine

authors： Morelli A,Singer M,Ranieri VM,D'Egidio A,Mascia L,Orecchioni A,Piscioneri F,Guarracino F,Greco E,Peruzzi M,Biondi-Zoccai G,Frati G,Romano SM

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:The Guillain-Barré syndrome (GBS) is an acute inflammatory polyneuropathy related to autoimmunity. However, no conclusive etiological concept has yet been found. We examined the variation in autoantibodies to lipids in serum of GBS patients in response to the course of the disease but investigated titer modif...

journal_title：Intensive care medicine

authors： Nakos G,Tziakou E,Maneta-Peyret L,Nassis C,Lekka ME

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:We examined in rabbits the effects of more than 48 h of mechanical ventilation on the contractile properties and fiber type adaptations of the respiratory muscles. DESIGN AND SETTING:Experimental prospective study in a university laboratory. ANIMALS AND INTERVENTIONS:Nineteen rabbits were randomly allocated...

journal_title：Intensive care medicine

authors： Capdevila X,Lopez S,Bernard N,Rabischong E,Ramonatxo M,Martinazzo G,Prefaut C

更新日期：2003-01-01 00:00:00

abstract：PURPOSE:Relatives of intensive care unit (ICU) patients suffer emotional distress that impairs their ability to acquire the information they need from the staff. We sought to evaluate whether providing relatives with a list of important questions was associated with better comprehension on day 5. METHODS:Randomized, p...

journal_title：Intensive care medicine

authors： Azoulay E,Forel JM,Vinatier I,Truillet R,Renault A,Valade S,Jaber S,Durand-Gasselin J,Schwebel C,Georges H,Merceron S,Cariou A,Moussa M,Hraiech S,Argaud L,Leone M,Curtis JR,Kentish-Barnes N,Jouve E,Papazian L

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To present the efficacy and tolerability of a new oral dosage form of the calcium antagonist nitrendipine compared to nifedipine capsules in patients with hypertensive emergency. DESIGN:Multicenter randomized double blind clinical study. SETTING:23 study centres (hospitals) in Germany. PATIENTS:161 patient...

journal_title：Intensive care medicine

authors： Rohr G,Reimnitz P,Blanke P

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:To study the incidence and clinical characteristics of delayed cerebral thrombosis in bacterial meningitis patients. METHODS:We assessed the incidence and clinical characteristics of delayed cerebral thrombosis in adults with cerebrospinal fluid (CSF) culture-proven community-acquired bacterial meningitis incl...

journal_title：Intensive care medicine

authors： Lucas MJ,Brouwer MC,van de Beek D

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:There is still a lack of knowledge on the age-dependent relation between a reduction in cerebral perfusion pressure (CPP) and compromised brain perfusion leading to excessive transmitter release and brain damage cascades. The hypothesis is that an age-dependent lower threshold of cerebral blood flow (CBF) aut...

journal_title：Intensive care medicine

authors： Walter B,Aisenpreis K,Fritz HG,Soukup J,Eiselt M,Bauer R

更新日期：2010-06-01 00:00:00

abstract：:Neuromuscular blocking agents (NMBAs) inhibit patient-initiated active breath and the risk of high tidal volumes and consequent high transpulmonary pressure swings, and minimize patient/ ventilator asynchrony in acute respiratory distress syndrome (ARDS). Minimization of volutrauma and ventilator-induced lung injury (...

journal_title：Intensive care medicine

authors： Hraiech S,Yoshida T,Annane D,Duggal A,Fanelli V,Gacouin A,Heunks L,Jaber S,Sottile PD,Papazian L

更新日期：2020-12-01 00:00:00

abstract：:A total of 6178 persons with out-of-hospital (70%) and in hospital (30%) cardiac arrests from the first of January 1982 until the end of 1989 were reviewed retrospectively with respect to 4 variables, contributing to a score for specific prediction of poor prognosis (cut-off point: greater than 3 points). These includ...

journal_title：Intensive care medicine

authors： Martens PR,Mullie A,Buylaert W,Calle P,van Hoeyweghen R

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:Controversies concerning the pivotal trial and negative results from other Drotrecogin alfa activated (DAA) trials have raised questions about its efficacy in severe sepsis patients. Based on all available evidence, our study aimed to respond to: (1) What is the current probability that DAA is not better tha...

journal_title：Intensive care medicine

authors： Kalil AC,Sun J

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:To describe the use of volumetric capnography, a plot of expired CO(2) concentration against expired volume, in monitoring fibrinolytic treatment of major pulmonary embolism. DESIGN AND SETTING:Two case reports in the emergency department of a teaching hospital. PATIENTS:Two conscious and spontaneously brea...

journal_title：Intensive care medicine

authors： Verschuren F,Heinonen E,Clause D,Roeseler J,Thys F,Meert P,Marion E,El Gariani A,Col J,Reynaert M,Liistro G

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:Endotracheal suctioning can cause alveolar collapse and impede ventilation. One reason is the gas flow through a single-lumen endotracheal tube (ETT) provoking a gradient between airway opening and tracheal (P(tr)) pressures. Separately extending the patient tubing limbs of a suitable ventilator into the trac...

journal_title：Intensive care medicine

authors： Reissmann H,Böhm SH,Suárez-Sipmann F,Tusman G,Buschmann C,Maisch S,Pesch T,Thamm O,Plümers C,Schulte am Esch J,Hedenstierna G

更新日期：2005-03-01 00:00:00

abstract：:Owing to an oversight by the authors, Figure 2 in this article was not the version intended for publication. The correct Figure 2, reproduced here, features footnote symbols and Figure 2b includes three studies as described in the main text. ...

journal_title：Intensive care medicine

authors： Fujii T,Ganeko R,Kataoka Y,Furukawa TA,Featherstone R,Doi K,Vincent JL,Pasero D,Robert R,Ronco C,Bagshaw SM

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To characterize hemodynamic changes during experimental aspiration pneumonitis, paying special attention to echocardiographic assessment. DESIGN AND SETTING:Animal study in a university-based research laboratory. SUBJECTS:Fourteen mechanically ventilated New Zealand white rabbits INTERVENTIONS:We instilled...

journal_title：Intensive care medicine

authors： Fraisse A,Bregeon F,Delpierre S,Gaudart J,Payan MJ,Pugin J,Papazian L

更新日期：2007-02-01 00:00:00

abstract：:Breathing pattern was studied non-invasively in 20 coronary artery bypass surgery patients before the operation and post-operatively after weaning from mechanical ventilation. Post-operatively minute ventilation (VE), breathing frequency (Fr) and mean inspiratory flow (VT/TI) increased (28%, 42%, 27%; p less than 0.01...

journal_title：Intensive care medicine

authors： Tulla H,Takala J,Alhava E,Huttunen H,Kari A,Manninen H

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVES:Trunk position at 45 degrees from the horizontal is associated with a decreased risk of gastroesophageal aspiration. The objectives of this study were to determine the accuracy of trunk flexion estimates compared to a reference standard measurement, and to determine agreement about trunk flexion among ICU cl...

journal_title：Intensive care medicine

authors： McMullin JP,Cook DJ,Meade MO,Weaver BR,Letelier LM,Kahmamoui K,Higgins DA,Guyatt GH

更新日期：2002-03-01 00:00:00

abstract：PURPOSE:Limited data exist on the correlation between higher flow rates of high-flow nasal cannula (HFNC) and its physiologic effects in patients with acute hypoxemic respiratory failure (AHRF). We assessed the effects of HFNC delivered at increasing flow rate on inspiratory effort, work of breathing, minute ventilatio...

journal_title：Intensive care medicine

authors： Mauri T,Alban L,Turrini C,Cambiaghi B,Carlesso E,Taccone P,Bottino N,Lissoni A,Spadaro S,Volta CA,Gattinoni L,Pesenti A,Grasselli G

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:Hypoxia-ischemia (HI), as a major cause of fetal brain damage, has long-lasting neurological implications. Therefore, therapeutic interventions that attenuate the neuropathological outcome of HI while also improving the neurofunctional outcome are of paramount clinical importance. The aim of this study was to i...

journal_title：Intensive care medicine

authors： Fathali N,Lekic T,Zhang JH,Tang J

更新日期：2010-09-01 00:00:00

abstract：:The reliability of cardiac output estimation by thermodilution during artificial ventilation was studied in anesthetized pigs at the right side of the heart. The estimates exhibited a cyclic modulation related to the ventilation. The amplitude of the modulation was independent of the level of positive end-expiratory p...

journal_title：Intensive care medicine

authors： Jansen JR,Versprille A

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:Because non-invasive mechanical ventilation (NIV) is increasingly used, new devices, both ventilators and interfaces, have been continuously proposed for clinical use in recent years. To provide the clinicians with valuable information about ventilators and interfaces for NIV, several bench studies evaluating a...

journal_title：Intensive care medicine

authors： Olivieri C,Costa R,Conti G,Navalesi P

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Blood O(2) saturation and lactate concentration gradients from superior vena cava (SVC) to pulmonary artery (PA) occur in critically ill patients. These gradients (DeltaSO(2) and Delta[Lac]) may be positive or negative. We tested the hypothesis that positive DeltaSO(2) and Delta[Lac] are associated with impro...

journal_title：Intensive care medicine

authors： Gutierrez G,Comignani P,Huespe L,Hurtado FJ,Dubin A,Jha V,Arzani Y,Lazzeri S,Sosa L,Riva J,Kohn W,Suarez D,Lacuesta G,Olmos D,Mizdraji C,Ojeda A

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Trustworthy clinical practice guidelines (CPGs) require identification and careful management of conflicts of interest (COIs) among all participants in the guideline development. Furthermore, COIs are more common than anticipated. However, there are no universally accepted methods to identify and manage COIs...

journal_title：Intensive care medicine

authors： Alhazzani W,Lewis K,Jaeschke R,Rochwerg B,Møller MH,Evans L,Wilson KC,Patel S,Coopersmith CM,Cecconi M,Guyatt G,Akl EA

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of basic life support, time to first defibrillation and emergency medical service arrival time on neurologic outcome and expenses for hospital care in patients after cardiac arrest. SETTING:Large urban emergency medical services system and emergency department in a 2000-bed university...

journal_title：Intensive care medicine

authors： Bur A,Kittler H,Sterz F,Holzer M,Eisenburger P,Oschatz E,Kofler J,Laggner AN

更新日期：2001-09-01 00:00:00

abstract：:Nosocomial pneumonia continues to represent a significant cause of morbidity and mortality in hospitalized patients. Bacteria are responsible for greater than 90% of the pneumonias, the most common isolates being aerobic Gram-negative bacilli and S. aureus. Cornerstones of treatment are intravenous antibiotics and sup...

journal_title：Intensive care medicine

authors： Unertl KE,Lenhart FP,Forst H,Peter K

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:Evidence of variation in mortality after surgery may indicate preventable postoperative death. We sought to determine if regional differences in outcome were present in surgical patients admitted to critical care in the UK. METHODS:We extracted data on admission characteristics, case mix and outcome of all pat...

journal_title：Intensive care medicine

authors： Gillies MA,Power GS,Harrison DA,Fleming A,Cook B,Walsh TS,Pearse RM,Rowan KM

更新日期：2015-10-01 00:00:00

abstract：:The Editor-in-Chief has retracted this article [1] because a number of studies included in this review [2, 3, 4] (originally cited as references 98, 128, 129) have since been retracted. Consequently, this has rendered the content of the review unreliable. ...

journal_title：Intensive care medicine

authors： Editorial Office of Intensive Care Medicine.

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:To investigate the accuracy of lung ultrasonography (LUS) in the quantification of lung water in critically ill patients by using quantitative computed tomography (CT) as the gold standard for the determination of lung weight. METHODS:Twenty consecutive patients admitted to an intensive care unit who underwe...

journal_title：Intensive care medicine

authors： Baldi G,Gargani L,Abramo A,D'Errico L,Caramella D,Picano E,Giunta F,Forfori F

更新日期：2013-01-01 00:00:00