The American-European Consensus Conference on ARDS, part 2. Ventilatory, pharmacologic, supportive therapy, study design strategies and issues related to recovery and remodeling.

abstract：:Helicobacter pylori is estimated to infect over 50% of the world's population, the majority of whom are asymptomatic. Although most research to date has focused on local gastroduodenal disease manifestations, the potential impact of H. pylori infection and the associated chronic active inflammation on systemic disease...

journal_title：Intensive care medicine

authors： Robertson MS,Clancy RL,Cade JF

更新日期：2003-11-01 00:00:00

abstract：PURPOSE:To assess the effects of alveolar recruitment maneuvers (ARMs) on clinical outcomes in patients with acute respiratory distress syndrome (ARDS). METHODS:We conducted a search of the MEDLINE, EMBASE, LILACS, CINAHL, CENTRAL, Scopus, and Web of Science (from inception to July 2014) databases for all (i.e. no lan...

journal_title：Intensive care medicine

authors： Suzumura EA,Figueiró M,Normilio-Silva K,Laranjeira L,Oliveira C,Buehler AM,Bugano D,Passos Amato MB,Ribeiro Carvalho CR,Berwanger O,Cavalcanti AB

更新日期：2014-09-01 00:00:00

abstract：:Breathing pattern was studied non-invasively in 20 coronary artery bypass surgery patients before the operation and post-operatively after weaning from mechanical ventilation. Post-operatively minute ventilation (VE), breathing frequency (Fr) and mean inspiratory flow (VT/TI) increased (28%, 42%, 27%; p less than 0.01...

journal_title：Intensive care medicine

authors： Tulla H,Takala J,Alhava E,Huttunen H,Kari A,Manninen H

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:To study the incidence and clinical characteristics of delayed cerebral thrombosis in bacterial meningitis patients. METHODS:We assessed the incidence and clinical characteristics of delayed cerebral thrombosis in adults with cerebrospinal fluid (CSF) culture-proven community-acquired bacterial meningitis incl...

journal_title：Intensive care medicine

authors： Lucas MJ,Brouwer MC,van de Beek D

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Based on limited data, Candida sp. isolates from bronchoalveolar lavage (BAL) cultures in immunocompetent patients are thought to be contaminants rather than pathogens. The objective of this study was to determine the clinical significance of Candida sp. isolated from BAL cultures in critically ill trauma pat...

journal_title：Intensive care medicine

authors： Wood GC,Mueller EW,Croce MA,Boucher BA,Fabian TC

更新日期：2006-04-01 00:00:00

abstract：PURPOSE:We examined whether influenza vaccination affects 1-year risk of myocardial infarction, stroke, heart failure, pneumonia, and death among intensive care unit (ICU) survivors aged ≥ 65 years. METHODS:Danish Intensive Care Database data on all elderly ( ≥ 65 years) patients hospitalized in Danish ICUs in the per...

journal_title：Intensive care medicine

authors： Christiansen CF,Thomsen RW,Schmidt M,Pedersen L,Sørensen HT

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:To test the hypothesis that RNA editing is altered in pediatric patients with cyanotic congenital heart disease (CHD) and to determine whether A-to-I RNA editing is associated with the postoperative course following cardiac surgery. Cyanotic CHD is associated with a unique pathophysiology caused by chronic hypo...

journal_title：Intensive care medicine

authors： Borik S,Simon AJ,Nevo-Caspi Y,Mishali D,Amariglio N,Rechavi G,Paret G

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVES:Previous studies on therapeutic interventions in sepsis have assumed stability of the measure of splanchnic blood flow throughout the study. We assessed the variability of splanchnic blood flow during stable global hemodynamics in eight patients with sepsis requiring treatment with dobutamine and/or norepine...

journal_title：Intensive care medicine

authors： Sakka SG,Reinhart K,Wegscheider K,Meier-Hellmann A

更新日期：2001-08-01 00:00:00

abstract：PURPOSE:To develop a liver function-related risk prediction tool to identify acute-on-chronic liver failure patients at greatest risk of in-hospital mortality. METHODS:The LiFe (liver, injury, failure, evaluation) score, was constructed based on the opinions of 157 intensivists within the European Society for Intensiv...

journal_title：Intensive care medicine

authors： Edmark C,McPhail MJW,Bell M,Whitehouse T,Wendon J,Christopher KB

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:In patients with severe sepsis, no randomized clinical trial has tested the concept of de-escalation of empirical antimicrobial therapy. This study aimed to compare the de-escalation strategy with the continuation of an appropriate empirical treatment in those patients. METHODS:This was a multicenter non-bl...

journal_title：Intensive care medicine

authors： Leone M,Bechis C,Baumstarck K,Lefrant JY,Albanèse J,Jaber S,Lepape A,Constantin JM,Papazian L,Bruder N,Allaouchiche B,Bézulier K,Antonini F,Textoris J,Martin C,AZUREA Network Investigators.

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVES:To examine whether urgent orotracheal intubation (OI) can induce bacteremia. To find predictive factors for post-intubation bacteremia. DESIGN:Prospective observational study. SETTING:Seventeen-bed medical intensive care unit in a university hospital. PATIENTS:Sixty-eight adult intensive care patients und...

journal_title：Intensive care medicine

authors： Rijnders BJ,Wilmer A,Van Eldere J,Van Wijngaerden E

更新日期：2001-02-01 00:00:00

abstract：PURPOSE:Neurologic and endothelial injury biomarkers are associated with prolonged delirium during critical illness and may reflect injury pathways that lead to poor long-term outcomes. We hypothesized that blood-brain barrier (BBB), neuronal, and endothelial injury biomarkers measured during critical illness are assoc...

journal_title：Intensive care medicine

authors： Hughes CG,Patel MB,Brummel NE,Thompson JL,McNeil JB,Pandharipande PP,Jackson JC,Chandrasekhar R,Ware LB,Ely EW,Girard TD

更新日期：2018-03-01 00:00:00

abstract：:We studied the effect of thiopental loading during resuscitation of 53 patients following cardiopulmonary arrest and compared the outcome with that found in 54 patients treated conventionally in the 30 previous months. Thiopental therapy (10 mg/kg i.v.) was begun within 30 min of the arrest once hemodynamic stability ...

journal_title：Intensive care medicine

authors： Monsalve F,Rucabado L,Ruano M,Cuñat J,Lacueva V,Viñuales A

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:To determine the clinical epidemiology of invasive group A streptococcal disease (IGASD) and identify predictors of admissions into an intensive care unit (ICU). DESIGN:A cross-sectional study. SETTING:Retrospective review of data. PATIENTS:A total of 204 patients hospitalized throughout the state of Flori...

journal_title：Intensive care medicine

authors： Mulla ZD

更新日期：2002-12-01 00:00:00

abstract：PURPOSE:To investigate the relationship between hemoglobin (Hgb) and brain tissue oxygen tension (PbtO(2)) after severe traumatic brain injury (TBI) and to examine its impact on outcome. METHODS:This was a retrospective analysis of a prospective cohort of severe TBI patients whose PbtO(2) was monitored. The relationsh...

journal_title：Intensive care medicine

authors： Oddo M,Levine JM,Kumar M,Iglesias K,Frangos S,Maloney-Wilensky E,Le Roux PD

更新日期：2012-09-01 00:00:00

abstract：:In 9 Goettingen minipigs we studied the effect of E. coli bacteremia on effective pulmonary capillary pressure and the longitudinal distribution of pulmonary vascular resistance. Precapillary pressure gradient (dPa) was calculated as the difference between mean pulmonary artery pressure (MPP) and effective pulmonary c...

journal_title：Intensive care medicine

authors： Fretschner R,Klöss T,Guggenberger H,Heuser D,Schmid HJ,Widmann M

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:Endotracheal suctioning can cause alveolar collapse and impede ventilation. One reason is the gas flow through a single-lumen endotracheal tube (ETT) provoking a gradient between airway opening and tracheal (P(tr)) pressures. Separately extending the patient tubing limbs of a suitable ventilator into the trac...

journal_title：Intensive care medicine

authors： Reissmann H,Böhm SH,Suárez-Sipmann F,Tusman G,Buschmann C,Maisch S,Pesch T,Thamm O,Plümers C,Schulte am Esch J,Hedenstierna G

更新日期：2005-03-01 00:00:00

abstract：:A 42 year old pregnant woman was admitted in acute respiratory failure. Viral pneumonia was suspected and oxygen therapy, CPAP, water restriction and diuretics were started with good response. She remained febrile and had an abnormal chest X-ray, a diagnosis of miliary tuberculosis was confirmed by transbronchial fibr...

journal_title：Intensive care medicine

authors： Raimondi AC,Olmedo G,Roncoroni AJ

更新日期：1978-11-01 00:00:00

abstract：OBJECTIVE:To examine the benefits and risks of vasopressin or its analog terlipressin for patients with vasodilatory shock. DATA SOURCE:We searched the CENTRAL, MEDLINE, EMBASE, and LILACS databases (up to March 2011) as well as reference lists of articles and proceedings of major meetings; we also contacted trial aut...

journal_title：Intensive care medicine

authors： Polito A,Parisini E,Ricci Z,Picardo S,Annane D

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Trunk position at 45 degrees from the horizontal is associated with a decreased risk of gastroesophageal aspiration. The objectives of this study were to determine the accuracy of trunk flexion estimates compared to a reference standard measurement, and to determine agreement about trunk flexion among ICU cl...

journal_title：Intensive care medicine

authors： McMullin JP,Cook DJ,Meade MO,Weaver BR,Letelier LM,Kahmamoui K,Higgins DA,Guyatt GH

更新日期：2002-03-01 00:00:00

abstract：:In a randomized clinical trial the prophylactic effects of locally administered antimicrobials on quantitative colonization and respiratory infections were studied in intubated patients with an expected period of mechanical ventilation of greater than 6 days. Nineteen patients received 50 mg of polymyxin B and 80 mg o...

journal_title：Intensive care medicine

authors： Unertl K,Ruckdeschel G,Selbmann HK,Jensen U,Forst H,Lenhart FP,Peter K

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Adult studies evaluating corticosteroids have found varied efficacy. One study showing mortality benefit utilized fludrocortisone (FLU) and hydrocortisone (HC) (Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 288:862-871, 2002). Use of...

journal_title：Intensive care medicine

authors： Hebbar KB,Stockwell JA,Fortenberry JD

更新日期：2011-03-01 00:00:00

abstract：:In the past two years several guidelines for suggested components of emergency medical systems for children have been suggested, and for the first time, specific standards of pediatric trauma care have also been formulated. The American Academy of Pediatrics new Provisional Committee on Emergency Medicine has been cha...

journal_title：Intensive care medicine

authors： Haller JA,Beaver B

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:Although several advantages are attributed to tracheotomy in ICU patients requiring mechanical ventilation (MV), true benefits and the optimal timing of tracheotomy remain controversial. In this study, we compared early tracheotomy (ET) with prolonged intubation (PI) in severely ill patients requiring prolong...

journal_title：Intensive care medicine

authors： Blot F,Similowski T,Trouillet JL,Chardon P,Korach JM,Costa MA,Journois D,Thiéry G,Fartoukh M,Pipien I,Bruder N,Orlikowski D,Tankere F,Durand-Zaleski I,Auboyer C,Nitenberg G,Holzapfel L,Tenaillon A,Chastre J,Laplanch

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:Critically ill patients often require CT scans. Adverse events (AE) can occur during intra-hospital transport (IHT). The aim of this prospective study was to determine the diagnostic and therapeutic yield and the safety of CT scans in ICU patients. METHODS:All ICU patients having a CT scan for diagnostic purpo...

journal_title：Intensive care medicine

authors： Aliaga M,Forel JM,De Bourmont S,Jung B,Thomas G,Mahul M,Bisbal M,Nougaret S,Hraiech S,Roch A,Chaumoitre K,Jaber S,Gainnier M,Papazian L

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:Measurement of functional residual capacity (FRC) during controlled and especially during assisted ventilation remains a challenge in the physiological evaluation of ventilated patients. To validate a bag-in-box closed helium dilution technique allowing measurements both during pressure-controlled (PCV) and p...

journal_title：Intensive care medicine

authors： Di Marco F,Rota Sperti L,Milan B,Stucchi R,Centanni S,Brochard L,Fumagalli R

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVES:To document the effect of neurocritical care, delivered by specialist staff and based on protocol-driven therapy aimed at intracranial pressure (ICP) and cerebral perfusion pressure (CPP) targets, on outcome in acute head injury. DESIGN:Retrospective record review to compare presentation, therapy and outcom...

journal_title：Intensive care medicine

authors： Patel HC,Menon DK,Tebbs S,Hawker R,Hutchinson PJ,Kirkpatrick PJ

更新日期：2002-05-01 00:00:00

abstract：:The recording of intratracheal pressure in patients breathing through a tracheostomy tube is marred by methodological problems. In model experiments it has been shown that the introduction of a recording catheter into the tracheostomy tube alters the recorded pressure by as much as 20-40%. To avoid such inaccuracy, a ...

journal_title：Intensive care medicine

authors： Holst M,Striem J,Hedenstierna G

更新日期：1990-01-01 00:00:00

abstract：:Fifteen polytrauma patients with asymmetric pulmonary contusion were treated with differential lung ventilation (DLV) for a mean of 106 hours (range 24-298, median 83). The differential time constant (Tc), compliance (Ct), inspiratory and expiratory airway resistance (Rawinsp, Rawexp) and peak-airway pressure (Pawpeak...

journal_title：Intensive care medicine

authors： Zandstra DF,Stoutenbeek CP,Bams JL

更新日期：1989-01-01 00:00:00

abstract：:One hundred consecutive patients were interviewed between the 3rd and 7th days, inclusive, of their discharge from an intensive care unit to a general ward. The patients' recall of events related to their admission to the ICU was generally poor, and 41% of them felt that they had been confused at some time during thei...

journal_title：Intensive care medicine

authors： Jones J,Hoggart B,Withey J,Donaghue K,Ellis BW

更新日期：1979-05-01 00:00:00