A model: systems management of life threatening injuries in children for the state of Maryland, USA.

abstract：:Administration of C1-esterase inhibitor (C1-INH) attenuates myocardial necrosis and sustains normal cardiac performance after myocardial ischemia and reperfusion in animal experiments. We report on our first experience of C1-INH application as rescue therapy in patients undergoing emergency surgical revascularization ...

journal_title：Intensive care medicine

authors： Bauernschmitt R,Böhrer H,Hagl S

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVES:(a) To measure gastric tonometry values in critically ill patients with peritonitis and to assess the impact of epidural analgesia on these values. (b) To assess the impact of epidural analgesia on gastro-intestinal motility by abdominal ultrasound and paracetamol absorption. (c) To observe any change in cli...

journal_title：Intensive care medicine

authors： Spackman DR,McLeod AD,Prineas SN,Leach RM,Reynolds F

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:To examine the attitudes of the general public regarding who should decide about the withdrawal of life support and to compare these attitudes with those of intensive care personnel. DESIGN:Nationwide postal questionnaire survey. SETTING:Sweden. PARTICIPANTS:One thousand one hundred ninety-six randomly sel...

journal_title：Intensive care medicine

authors： Sjökvist P,Nilstun T,Svantesson M,Berggren L

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVES:Circulating levels of the proinflammatory mediator High Mobility Group Box Protein 1 (HMGB1) are increased in septic patients and may contribute to sepsis-induced organ dysfunction. Although HMGB1 has been shown to activate neutrophils from healthy volunteers, the responses of neutrophils from septic patient...

journal_title：Intensive care medicine

authors： Silva E,Arcaroli J,He Q,Svetkauskaite D,Coldren C,Nick JA,Poch K,Park JS,Banerjee A,Abraham E

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:The role of haemofiltration as an adjunctive treatment of sepsis remains a contentious issue. To address the role of dose and to explore the biological effects of haemofiltration we compared the effects of standard and high-volume haemofiltration (HVHF) in a peritonitis-induced model of porcine septic shock. ...

journal_title：Intensive care medicine

authors： Sykora R,Chvojka J,Krouzecky A,Radej J,Karvunidis T,Varnerova V,Novak I,Matejovic M

更新日期：2009-02-01 00:00:00

abstract：INTRODUCTION:Faecal peritonitis (FP) is a common cause of sepsis and admission to the intensive care unit (ICU). The Genetics of Sepsis and Septic Shock in Europe (GenOSept) project is investigating the influence of genetic variation on the host response and outcomes in a large cohort of patients with sepsis admitted t...

journal_title：Intensive care medicine

authors： Tridente A,Clarke GM,Walden A,McKechnie S,Hutton P,Mills GH,Gordon AC,Holloway PA,Chiche JD,Bion J,Stuber F,Garrard C,Hinds CJ,GenOSept Investigators.

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:To study the influence of continuous administration of heparin on platelet function in intensive care patients. DESIGN:Prospective, serial investigation. SETTING:Clinical investigation on a surgical and neurosurgical intensive care unit in a university hospital. PATIENTS:The study included 45 patients: 15 ...

journal_title：Intensive care medicine

authors： Boldt J,Müller M,Rothe A,Lenzen P,Hempelmann G

更新日期：1997-05-01 00:00:00

abstract：:Streptococcus pneumoniae is responsible for two-thirds of ICU admissions due to community-acquired pneumonia (CAP) and is the leading cause of CAP-related death. Early death is principally due to cardiovascular collapse, whereas late death is associated with hypoxemic respiratory failure. Outcome depends on interactio...

journal_title：Intensive care medicine

authors： Luján M,Gallego M,Rello J

更新日期：2006-07-01 00:00:00

abstract：:A veno-venous to-and-fro bypass method through a single blood access for extracorporeal lung assist with an artificial membrane lung is introduced. A premature newborn with severe respiratory distress was treated with this method. A 12 Fr. single lumen catheter with a spiral-embedded thin-wall, 0.25 mm in wall thickne...

journal_title：Intensive care medicine

authors： Tsuno K,Terasaki H,Tsutsumi R,Sadanaga M,Higashi K,Morioka T

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVES:To examine whether urgent orotracheal intubation (OI) can induce bacteremia. To find predictive factors for post-intubation bacteremia. DESIGN:Prospective observational study. SETTING:Seventeen-bed medical intensive care unit in a university hospital. PATIENTS:Sixty-eight adult intensive care patients und...

journal_title：Intensive care medicine

authors： Rijnders BJ,Wilmer A,Van Eldere J,Van Wijngaerden E

更新日期：2001-02-01 00:00:00

abstract：PURPOSE:Critical care ultrasonography has utility for the diagnosis and management of critical illness and is in widespread use by frontline intensivists. As there is a need for research to validate and extend its utility, the Editor of Intensive Care Medicine included critical care ultrasonography as a topic in the IC...

journal_title：Intensive care medicine

authors： Mayo P,Arntfield R,Balik M,Kory P,Mathis G,Schmidt G,Slama M,Volpicelli G,Xirouchaki N,McLean A,Vieillard-Baron A

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:The purpose of the study was do describe the architecture of accretions occurring on the tips of central venous catheters (CVC). DESIGN:A conservative procedure was used followed by two different techniques of electron microscopy. SETTING AND PATIENTS:the study included 19 catheters which have been used on ...

journal_title：Intensive care medicine

authors： Poisson DM,Touquet S,Bercault N,Arbeille B

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To report the first case of ARDS in children treated with nitric oxide (NO) inhalation. METHODS:A 13-months infant presented with BPD and severe hypoxemia related to RSV infection and ARDS. Inhaled NO was delivered in the ventilatory circuit of a continuous flow ventilator (Babylog 8000, Dräger) in a concent...

journal_title：Intensive care medicine

authors： Leclerc F,Riou Y,Martinot A,Storme L,Hue V,Flurin V,Deschildre A,Sadik A

更新日期：1994-08-01 00:00:00

abstract：RATIONALE:Delirium incidence in intensive care unit (ICU) patients is high and associated with poor outcome. Identification of high-risk patients may facilitate its prevention. PURPOSE:To develop and validate a model based on data available at ICU admission to predict delirium development during a patient's complete I...

journal_title：Intensive care medicine

authors： Wassenaar A,van den Boogaard M,van Achterberg T,Slooter AJ,Kuiper MA,Hoogendoorn ME,Simons KS,Maseda E,Pinto N,Jones C,Luetz A,Schandl A,Verbrugghe W,Aitken LM,van Haren FM,Donders AR,Schoonhoven L,Pickkers P

更新日期：2015-06-01 00:00:00

abstract：INTRODUCTION:Extracorporeal carbon dioxide removal (ECCO2R) has been proposed for hypercapnic respiratory failure in chronic obstructive pulmonary disease (COPD) exacerbations, to avoid intubation or reduce length of invasive ventilation. Balance of risks, efficacy, and benefits of ECCO2R in patients with COPD is uncle...

journal_title：Intensive care medicine

authors： Sklar MC,Beloncle F,Katsios CM,Brochard L,Friedrich JO

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:The intravenous fluid 6% hydroxyethyl starch (130/0.4) (6% HES 130/0.4) is used widely for resuscitation but there is limited information on its efficacy and safety. A large-scale multi-centre randomised controlled trial (CHEST) in critically ill patients is currently underway comparing fluid resuscitation with...

journal_title：Intensive care medicine

authors： Crystalloid versus Hydroxyethyl Starch Trial (CHEST) Management Committee.

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:Infection is the most frequent cause of acute respiratory distress syndrome (ARDS). However, little is known about the influence of infection sites on ARDS. This study aimed to assess the associations of infection sites with ARDS development and mortality in critically ill infected patients. DESIGN:Prospecti...

journal_title：Intensive care medicine

authors： Sheu CC,Gong MN,Zhai R,Bajwa EK,Chen F,Thompson BT,Christiani DC

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:Sedatives administered to critically ill children should be titrated to effect, because both under- and oversedation may have negative effects. We conducted a systematic review to examine reported incidences of under-, optimal, and oversedation in critically ill children receiving intensive care. METHODS:A sys...

journal_title：Intensive care medicine

authors： Vet NJ,Ista E,de Wildt SN,van Dijk M,Tibboel D,de Hoog M

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To assess if the observed respiratory cycle-related variation in intra-abdominal pressure is reliably quantifiable and a possible indirect indicator of abdominal compliance. Secondary issues were to assess the roles played by respiratory parameters in determining this oscillation and by patients' position in ...

journal_title：Intensive care medicine

authors： Sturini E,Saporito A,Sugrue M,Parr MJ,Bishop G,Braschi A

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To investigate nasal nitric oxide (NO) excretion, pulmonary NO excretion, and autoinhalation of nasally released NO at rest compared with that during moderate exercise in smokers and non-smokers. DESIGN:Prospective observational study. SETTING:University laboratory. PARTICIPANTS:Fourteen healthy adult volu...

journal_title：Intensive care medicine

authors： Busch T,Kuhlen R,Knorr M,Kelly K,Lewandowski K,Rossaint R,Falke KJ,Gerlach H

更新日期：2000-04-01 00:00:00

abstract：PURPOSE:To provide recommendations and standard operating procedures for intensive care units and hospital preparedness for an influenza pandemic. METHODS:Based on a literature review and expert opinion, a Delphi process was used to define the essential topics. RESULTS:Key recommendations include: Hospitals should in...

journal_title：Intensive care medicine

authors： Sprung CL,Zimmerman JL,Christian MD,Joynt GM,Hick JL,Taylor B,Richards GA,Sandrock C,Cohen R,Adini B,European Society of Intensive Care Medicine Task Force for Intensive Care Unit Triage during an Influenza Epidemic or Mass Disaster.

更新日期：2010-03-01 00:00:00

abstract：:We present a patient with evidence of severe intravascular hemolysis after mitral valve repair, an established method for the surgical treatment of mitral valve disease to avoid prosthesis related complications. The coincidence of this uncommon complication with hemodynamic instability due to pre-existing myocardial d...

journal_title：Intensive care medicine

authors： Seyr M,Hasibeder W,Furtwaegler W,Antretter H,Mutz NJ

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To report the feasibility of craniectomy with duraplasty in four patients with life-threatening encephalitis and, in particular, their long-term outcome. DESIGN:Report of four cases, analysis of the acute clinical course and neurological long-term sequelae. RESULTS:Generous craniectomy with duraplasty was p...

journal_title：Intensive care medicine

authors： Taferner E,Pfausler B,Kofler A,Spiss H,Engelhardt K,Kampfl A,Schmutzhard E

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:We examined in rabbits the effects of more than 48 h of mechanical ventilation on the contractile properties and fiber type adaptations of the respiratory muscles. DESIGN AND SETTING:Experimental prospective study in a university laboratory. ANIMALS AND INTERVENTIONS:Nineteen rabbits were randomly allocated...

journal_title：Intensive care medicine

authors： Capdevila X,Lopez S,Bernard N,Rabischong E,Ramonatxo M,Martinazzo G,Prefaut C

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:This study was undertaken to determine the delay of extubation attributable to ventilator-associated pneumonia (VAP) in comparison to other complications and complexity of surgery after repair of congenital heart lesions in neonates and children. METHODS:Cohort study in a pediatric intensive care unit of a t...

journal_title：Intensive care medicine

authors： Fischer JE,Allen P,Fanconi S

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:The evaluation of incidences and relating factors of severe persisting critical illness polyneuropathy (CIP) in survivors of multiple organ failure (MOF). DESIGN:Prospective study with an entry period of 24 months. Electrophysiological studies for the diagnosis of CIP were performed 1 or 2 days before the pa...

journal_title：Intensive care medicine

authors： Mohr M,Englisch L,Roth A,Burchardi H,Zielmann S

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:We undertook this study to evaluate the influence of the inspiration:expiration (I:E) ratio on intracranial pressure and cerebral perfusion in patients with acute stroke. DESIGN:Ventilated patients with acute stroke were examined under a protocol involving variations of I:E ratio from 1:2 to 1:1 to 1:2 under...

journal_title：Intensive care medicine

authors： Georgiadis D,Schwarz S,Kollmar R,Baumgartner RW,Schwab S

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To measure muscle blood flow (Qtis) and oxygen consumption (VO(2)tis) in septic and non-septic critically ill patients by near-infrared spectroscopy (NIRS). SETTING:Surgical intensive care unit of a university hospital. PATIENTS AND PARTICIPANTS:Four patients with septic shock, eight post-surgical criticall...

journal_title：Intensive care medicine

authors： Girardis M,Rinaldi L,Busani S,Flore I,Mauro S,Pasetto A

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:To determine if the plasma levels of three endothelial-specific proteins, von Willebrand factor (vWF), tissue factor pathway inhibitor (TFPI) and thrombomodulin (TM) may be useful in predicting the development of acute respiratory distress syndrome (ARDS). DESIGN:Blood samples were obtained from normal healt...

journal_title：Intensive care medicine

authors： Bajaj MS,Tricomi SM

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of basic life support, time to first defibrillation and emergency medical service arrival time on neurologic outcome and expenses for hospital care in patients after cardiac arrest. SETTING:Large urban emergency medical services system and emergency department in a 2000-bed university...

journal_title：Intensive care medicine

authors： Bur A,Kittler H,Sterz F,Holzer M,Eisenburger P,Oschatz E,Kofler J,Laggner AN

更新日期：2001-09-01 00:00:00