Plasma fibronectin and complement following infusion of colloidal solutions after spinal anaesthesia.

Abstract:

:A randomized study of 30 patients undergoing uncomplicated surgery under spinal anesthesia was conducted to assess the influence of colloids on the kinetics of plasma fibronectin and complement. Both are opsonins of the reticuloendothelial system; moreover fibronectin is concerned with host resistance against septic complications following trauma and surgery. The patients were assigned to receive either Ringer's lactate (Group 1), gelatin (Group 2) or dextran 40 (Group 3). Blood samples were withdrawn before colloids or Ringer's infusion and during the 4 postoperative days. There was a reduction in plasma fibronectin throughout the study in groups 1 and 3, but an increase in group 2 by 24 h. The adhesion of plasma fibronectin to gelatin was maximal 1 h after infusion (44%) and remained significant up to day 2 in group 2. There was no relationship in groups 1 and 3. C3 and C4 components of complement exhibited a low value in the early post-operative period, due to hemodilution. This study shows an in vivo fibronectin-gelatin interaction, and suggests that gelatin infusion inhibits the increased shift of plasma fibronectin at the site of tissue injury after surgery.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Vedrinne JM,Hoen JP,Bussery D,Veyssere C,Richard M,Motin J

doi

10.1007/BF01691428

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

83-6

issue

2

eissn

0342-4642

issn

1432-1238

journal_volume

17

pub_type

临床试验,杂志文章,随机对照试验
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    journal_title:Intensive care medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/s001340050907

    authors: Gando S,Nanzaki S,Morimoto Y,Kobayashi S,Kemmotsu O

    更新日期:1999-06-01 00:00:00

  • In vitro validation of a metabolic monitor for gas exchange measurements in ventilated neonates.

    abstract:OBJECTIVE:To evaluate the Datex Deltatrac II for measurements in neonates requiring mechanical ventilation. DESIGN:Prospective laboratory evaluation, using a ventilated lung model and gas injection. During simulation of 79 neonatal respiratory settings, assessment of oxygen consumption (VO2), carbon dioxide production...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340000708

    authors: Behrends M,Kernbach M,Bräuer A,Braun U,Peters J,Weyland W

    更新日期:2001-01-01 00:00:00

  • Regional distribution of gas and tissue in acute respiratory distress syndrome. II. Physiological correlations and definition of an ARDS Severity Score. CT Scan ARDS Study Group.

    abstract:OBJECTIVES:(a) To assess whether differences in lung morphology observed in patients with adult respiratory distress syndrome (ARDS) are associated with differences in cardiorespiratory parameters, lung mechanics, and outcome. (b) To propose a new ARDS Severity Score to identify patients with a high mortality risk. DE...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340051317

    authors: Rouby JJ,Puybasset L,Cluzel P,Richecoeur J,Lu Q,Grenier P

    更新日期:2000-08-01 00:00:00

  • Plasma and lung concentrations of ceftazidime administered in continuous infusion to critically ill patients with severe nosocomial pneumonia.

    abstract:OBJECTIVE:To determine the steady-state plasma and epithelial lining fluid (ELF) concentrations of ceftazidime administered in continuous infusion to critically ill patients with severe nosocomial pneumonia. DESIGN:Prospective, open-label study. SETTING:An intensive care unit and research ward in a university hospita...

    journal_title:Intensive care medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00134-004-2171-2

    authors: Boselli E,Breilh D,Rimmelé T,Poupelin JC,Saux MC,Chassard D,Allaouchiche B

    更新日期:2004-05-01 00:00:00

  • Oxidative parameters and mortality in sepsis induced by cecal ligation and perforation.

    abstract:OBJECTIVE:This study assessed parameters of free radical damage to biomolecules, mitochondrial superoxide production, superoxide dismutase, and catalase activities and their relationship to sepsis mortality. DESIGN AND SETTING:Prospective animal study in a university laboratory for experimental. SUBJECTS:140 male Wis...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-003-1789-9

    authors: Ritter C,Andrades M,Frota Júnior ML,Bonatto F,Pinho RA,Polydoro M,Klamt F,Pinheiro CT,Menna-Barreto SS,Moreira JC,Dal-Pizzol F

    更新日期:2003-10-01 00:00:00

  • Interpretation of blood pressure signal: physiological bases, clinical relevance, and objectives during shock states.

    abstract::Achievement of a mean blood pressure (MBP) target is one of the hemodynamic goals to ensure an adequate blood perfusion pressure in critically ill patients. Arterial catheter allows for a continuous and precise monitoring of arterial pressure signal. In addition to giving a precise MBP monitoring, analysis of the bloo...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-010-2092-1

    authors: Augusto JF,Teboul JL,Radermacher P,Asfar P

    更新日期:2011-03-01 00:00:00

  • Short-term evaluation of sedation with sevoflurane administered by the anesthetic conserving device in critically ill patients.

    abstract:PURPOSE:Assessing feasibility and physiological effects of sedation with sevoflurane, administered with the anesthetic conserving device (AnaConDa), in comparison with propofol and remifentanil. METHODS:Seventeen patients undergoing mechanical ventilation underwent sedation with sevoflurane delivered with AnaConDa (ph...

    journal_title:Intensive care medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00134-009-1414-7

    authors: Migliari M,Bellani G,Rona R,Isgrò S,Vergnano B,Mauri T,Patroniti N,Pesenti A,Foti G

    更新日期:2009-07-01 00:00:00

  • Accumulation of hydroxyethyl starch in human and animal tissues: a systematic review.

    abstract:PURPOSE:To systematically review clinical and preclinical data on hydroxyethyl starch (HES) tissue storage. METHODS:MEDLINE (PubMed) was searched and abstracts were screened using defined criteria to identify articles containing original data on HES tissue accumulation. RESULTS:Forty-eight studies were included: 37 h...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-013-3156-9

    authors: Wiedermann CJ,Joannidis M

    更新日期:2014-02-01 00:00:00

  • Acute adrenal insufficiency resulting from adrenal hemorrhage as indicated by post-operative hypotension.

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    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF01704704

    authors: Szalados JE,Vukmir RB

    更新日期:1994-01-01 00:00:00

  • Inappropriate ventilator triggering caused by an in-line suction catheter.

    abstract:OBJECTIVE:To examine the phenomenon of inappropriate triggering caused by an in-line suction catheter. DESIGN:We used a test lung to assess inappropriate triggering in four ventilators with both pressure and flow triggering. RESULTS:With pressure triggering, inappropriate triggering occurred only in the presence of P...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-002-1239-0

    authors: Al-Khafaji A,Manning HL

    更新日期:2002-04-01 00:00:00

  • Association between urokinase haplotypes and outcome from infection-associated acute lung injury.

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    journal_title:Intensive care medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00134-007-0930-6

    authors: Arcaroli J,Sankoff J,Liu N,Allison DB,Maloney J,Abraham E

    更新日期:2008-02-01 00:00:00

  • Beta-lactamases: current situation and clinical importance.

    abstract::Production of beta-lactamases is the most important means of bacterial resistance to beta-lactam antibiotics. The traditional, plasmid-mediated beta-lactamases were initially confined to Enterobacteriaceae but have now spread to other genera and species including Pseudomonas aeruginosa, Haemophilus influenzae, and Nei...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/BF01745244

    authors: Garau J

    更新日期:1994-07-01 00:00:00

  • Neuromuscular dysfunction acquired in critical illness: a systematic review.

    abstract:OBJECTIVE:To determine the prevalence, risk factors, and outcomes of critical illness neuromuscular abnormalities (CINMA). DESIGN:Systematic review. DATA SOURCES AND STUDY SELECTION:MEDLINE, EMBASE, CINAHL, and the Cochrane Library were searched for reports on adult ICU patients who were evaluated for CINMA clinicall...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-007-0772-2

    authors: Stevens RD,Dowdy DW,Michaels RK,Mendez-Tellez PA,Pronovost PJ,Needham DM

    更新日期:2007-11-01 00:00:00

  • Regional variation in critical care provision and outcome after high-risk surgery.

    abstract:PURPOSE:Evidence of variation in mortality after surgery may indicate preventable postoperative death. We sought to determine if regional differences in outcome were present in surgical patients admitted to critical care in the UK. METHODS:We extracted data on admission characteristics, case mix and outcome of all pat...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-015-3980-1

    authors: Gillies MA,Power GS,Harrison DA,Fleming A,Cook B,Walsh TS,Pearse RM,Rowan KM

    更新日期:2015-10-01 00:00:00

  • Base deficit in immediate postoperative period of coronary surgery with cardiopulmonary bypass and length of stay in intensive care unit.

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    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-002-1587-9

    authors: Hugot P,Sicsic JC,Schaffuser A,Sellin M,Corbineau H,Chaperon J,Ecoffey C

    更新日期:2003-02-01 00:00:00

  • The impact of early goal-directed fluid management on survival in an experimental model of severe acute pancreatitis.

    abstract:PURPOSE:Severe acute pancreatitis (SAP) remains a life-threatening disease with classic etiology of systemic inflammatory response and mortality between 30 and 50 %. The aim of the present study is to compare two different treatment strategies of goal-directed hemodynamic management and evaluate their impact on surviva...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-012-2775-x

    authors: Trepte CJ,Bachmann KA,Stork JH,Friedheim TJ,Hinsch A,Goepfert MS,Mann O,Izbicki JR,Goetz AE,Reuter DA

    更新日期:2013-04-01 00:00:00

  • Could resuscitation be based on microcirculation data? We are not sure.

    abstract:: ...

    journal_title:Intensive care medicine

    pub_type: 信件

    doi:10.1007/s00134-018-5180-2

    authors: Monnet X,Saugel B

    更新日期:2018-06-01 00:00:00

  • Mechanism of injury influences quality of life in survivors of acute respiratory distress syndrome.

    abstract:OBJECTIVE:Growing evidence suggests that acute respiratory distress syndrome (ARDS) occurring as a consequence of primary (direct) lung injury differs from that resulting from secondary (indirect) lung injury in terms of radiographic appearance, response to interventions, and outcomes. We examined whether there are dif...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00134-006-0344-x

    authors: Parker CM,Heyland DK,Groll D,Caeser M

    更新日期:2006-11-01 00:00:00

  • Infant lung function testing in the intensive care unit.

    abstract::As a result of the previous shortage of tools to assess objectively the overall physiological status of the respiratory system in infants and young children, it has been difficult to measure the degree of physiological disorder or the response to therapy in respiratory diseases such as BPD, the pediatric version of AR...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/BF01704742

    authors: Hammer J,Newth CJ

    更新日期:1995-09-01 00:00:00

  • Epidemiological markers of coagulase-negative staphylococci.

    abstract::Several different epidemiological typing methods have been used in studies of coagulase-negative staphylococci; these include biotyping, antibiotic susceptibility pattern analysis, serological typing, phage typing, slime production detection, protein profile analysis, immunoblot fingerprinting and DNA typing. The most...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/BF01694703

    authors: Vandenesch F,Lina B,Lebeau Ch,Greenland TB,Etienne J

    更新日期:1993-01-01 00:00:00

  • Anti-phospholipid antibodies in serum from patients with Guillain-Barré syndrome.

    abstract:OBJECTIVE:The Guillain-Barré syndrome (GBS) is an acute inflammatory polyneuropathy related to autoimmunity. However, no conclusive etiological concept has yet been found. We examined the variation in autoantibodies to lipids in serum of GBS patients in response to the course of the disease but investigated titer modif...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-005-2736-8

    authors: Nakos G,Tziakou E,Maneta-Peyret L,Nassis C,Lekka ME

    更新日期:2005-10-01 00:00:00

  • Discontinuation of prolonged infusions of dexmedetomidine in critically ill children with heart disease.

    abstract:PURPOSE:To describe changes in hemodynamic variables, sedation, and pain score after discontinuation of prolonged infusions of dexmedetomidine in a pediatric population of critically ill cardiac patients. METHODS:Retrospective case series of patients who received continuous infusions of dexmedetomidine for longer than...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-011-2441-8

    authors: Burbano NH,Otero AV,Berry DE,Orr RA,Munoz RA

    更新日期:2012-02-01 00:00:00

  • Response to hypercapnic challenge is associated with successful weaning from prolonged mechanical ventilation due to brain stem lesions.

    abstract:OBJECTIVE:We propose that higher airway occlusion pressure (P0.1) responses to hypercapnic challenge (HC) indicate less severe injury. The study aim was to determine whether P0.1 responses to HC were associated with successful weaning after prolonged mechanical ventilation (PMV) in patients with brainstem lesions and t...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-008-1197-2

    authors: Wu YK,Lee CH,Shia BC,Tsai YH,Tsao TC

    更新日期:2009-01-01 00:00:00

  • Regional tidal ventilation and compliance during a stepwise vital capacity manoeuvre.

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    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-010-1995-1

    authors: Dargaville PA,Rimensberger PC,Frerichs I

    更新日期:2010-11-01 00:00:00

  • Gender-based differences in children with sepsis and ARDS: the ESPNIC ARDS Database Group.

    abstract::Male gender predisposes to severe sepsis and septic shock. This effect has been ascribed to higher levels of testosterone. The ESPNIC ARDS database was searched, to determine if there was evidence of a similar male preponderance in severe sepsis in prepubertal patients in spite of low levels of male sex hormones at th...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-003-1948-z

    authors: Bindl L,Buderus S,Dahlem P,Demirakca S,Goldner M,Huth R,Kohl M,Krause M,Kühl P,Lasch P,Lewandowski K,Merz U,Moeller J,Mohamad Y,Peters M,Porz W,Vierzig A,Rüchard J,Scharf J,Varnholt V,ESPNIC ARDS Database Group.

    更新日期:2003-10-01 00:00:00

  • Heart rate reduction with esmolol is associated with improved arterial elastance in patients with septic shock: a prospective observational study.

    abstract:PURPOSE:Ventricular-arterial (V-A) decoupling decreases myocardial efficiency and is exacerbated by tachycardia that increases static arterial elastance (Ea). We thus investigated the effects of heart rate (HR) reduction on Ea in septic shock patients using the beta-blocker esmolol. We hypothesized that esmolol improve...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-016-4351-2

    authors: Morelli A,Singer M,Ranieri VM,D'Egidio A,Mascia L,Orecchioni A,Piscioneri F,Guarracino F,Greco E,Peruzzi M,Biondi-Zoccai G,Frati G,Romano SM

    更新日期:2016-10-01 00:00:00

  • Remifentanil/midazolam versus fentanyl/midazolam for analgesia and sedation of mechanically ventilated neonates and young infants: a randomized controlled trial.

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    journal_title:Intensive care medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00134-012-2532-1

    authors: Welzing L,Oberthuer A,Junghaenel S,Harnischmacher U,Stützer H,Roth B

    更新日期:2012-06-01 00:00:00

  • Effect of a 2 g cimetidine infusion on twenty-four-hour intragastric pH in critically ill patients.

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    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF00262892

    authors: Tomé G,Fiasse R,Reynaert M,Mahieu P,Hanssens F

    更新日期:1988-01-01 00:00:00

  • Optimal sedation in pediatric intensive care patients: a systematic review.

    abstract:PURPOSE:Sedatives administered to critically ill children should be titrated to effect, because both under- and oversedation may have negative effects. We conducted a systematic review to examine reported incidences of under-, optimal, and oversedation in critically ill children receiving intensive care. METHODS:A sys...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-013-2971-3

    authors: Vet NJ,Ista E,de Wildt SN,van Dijk M,Tibboel D,de Hoog M

    更新日期:2013-09-01 00:00:00

  • Respiratory changes after open-heart surgery.

    abstract::Breathing pattern was studied non-invasively in 20 coronary artery bypass surgery patients before the operation and post-operatively after weaning from mechanical ventilation. Post-operatively minute ventilation (VE), breathing frequency (Fr) and mean inspiratory flow (VT/TI) increased (28%, 42%, 27%; p less than 0.01...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF01716198

    authors: Tulla H,Takala J,Alhava E,Huttunen H,Kari A,Manninen H

    更新日期:1991-01-01 00:00:00