Beta-lactamases: current situation and clinical importance.

abstract：:In critically ill patients, it is frequently challenging to identify who will benefit from admission to the intensive care unit and life-sustaining interventions when the chances of a meaningful outcome are unclear. In addition, the acute illness not only affects the patients but also family members or surrogates who ...

journal_title：Intensive care medicine

authors： Vink EE,Azoulay E,Caplan A,Kompanje EJO,Bakker J

更新日期：2018-09-01 00:00:00

abstract：PURPOSE:Clinical examination is often the first step to diagnose shock and estimate cardiac index. In the Simple Intensive Care Studies-I, we assessed the association and diagnostic performance of clinical signs for estimation of cardiac index in critically ill patients. METHODS:In this prospective, single-centre coho...

journal_title：Intensive care medicine

authors： Hiemstra B,Koster G,Wiersema R,Hummel YM,van der Harst P,Snieder H,Eck RJ,Kaufmann T,Scheeren TWL,Perner A,Wetterslev J,de Smet AMGA,Keus F,van der Horst ICC,SICS Study Group.

更新日期：2019-02-01 00:00:00

abstract：:Extracorporeal life support (ECLS) can support gas exchange in patients with the acute respiratory distress syndrome (ARDS). During ECLS, venous blood is drained from a central vein via a cannula, pumped through a semipermeable membrane that permits diffusion of oxygen and carbon dioxide, and returned via a cannula to...

journal_title：Intensive care medicine

authors： Combes A,Schmidt M,Hodgson CL,Fan E,Ferguson ND,Fraser JF,Jaber S,Pesenti A,Ranieri M,Rowan K,Shekar K,Slutsky AS,Brodie D

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:A readily available assessment of changes in pleural pressure would be useful for ventilator and fluid management in critically ill patients. We examined whether changes in pulmonary artery occlusion pressure (Ppao) adequately reflect respiratory changes in pleural pressure as assessed by changes in intraesop...

journal_title：Intensive care medicine

authors： Bellemare P,Goldberg P,Magder SA

更新日期：2007-11-01 00:00:00

abstract：PURPOSE:To determine the global metabolomic profile as measured in circulating plasma from surviving and non-surviving patients with community-acquired pneumonia (CAP) and sepsis. METHODS:Random, outcome-stratified case-control sample from a prospective study of 1,895 patients hospitalized with CAP and sepsis. Cases (...

journal_title：Intensive care medicine

authors： Seymour CW,Yende S,Scott MJ,Pribis J,Mohney RP,Bell LN,Chen YF,Zuckerbraun BS,Bigbee WL,Yealy DM,Weissfeld L,Kellum JA,Angus DC

更新日期：2013-08-01 00:00:00

abstract：:We investigated the levels of auto-PEEP and dynamic hyperinflation during high frequency jet ventilation (HFJV) and controlled mechanical ventilation (CMV) in six patients with chronic obstructive pulmonary disease within the first 36 h of acute exacerbation. The comparative evaluation was performed at similar conditi...

journal_title：Intensive care medicine

authors： Conti G,Bufi M,Rocco M,Calzecchi E,De Blasi RA,Antonelli M,Pelaia P,Gasparetto A

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To estimate the direct and indirect (contextual) effects of the factorized constituents of selective digestive decontamination and selective oropharyngeal decontamination (SDD/SOD), being topical antibiotic (TA) and protocolized antifungal prophylaxis (PAFP), on ICU-acquired candidemia. METHODS:A broad range o...

journal_title：Intensive care medicine

authors： Hurley JC

更新日期：2015-11-01 00:00:00

abstract：:Status epilepticus is one of the most frequent neurological emergencies in the intensive care unit. Standard treatment includes intravenous barbiturates, benzodiazepines and phenytoin. However, drug coma is sometimes necessary to control refractory status epilepticus. We report such a case, successfully treated by int...

journal_title：Intensive care medicine

authors： Borgeat A,Wilder-Smith OH,Jallon P,Suter PM

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To investigate the correlation between microalbuminuria and extravascular lung water in patients in septic shock who require mechanical ventilation for severe respiratory failure. DESIGN AND SETTING:Prospective, observational, clinical study in the 20-bed intensive care unit of a university hospital. PATIEN...

journal_title：Intensive care medicine

authors： Molnár Z,Szakmány T,Heigl P

更新日期：2003-03-01 00:00:00

abstract：PURPOSE:Computerized clinical decision support systems (CDSS) for intensive insulin therapy (IIT) generate recommendations using blood glucose (BG) values manually transcribed from testing devices to computers, a potential source of error. We quantified the frequency and effect of blood glucose transcription mismatches...

journal_title：Intensive care medicine

authors： Campion TR Jr,May AK,Waitman LR,Ozdas A,Gadd CS

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Current medical knowledge lacks specific information regarding creatine kinase (CK) elevation in influenza A pH1N1 (2009) infection. OBJECTIVES:Primary endpoints were correlation between CK at intensive care unit (ICU) admission and ICU mortality. Secondary endpoints were ICU length of stay (LOS), mechanica...

journal_title：Intensive care medicine

authors： Borgatta B,Pérez M,Rello J,Vidaur L,Lorente L,Socías L,Pozo JC,Pozo J,Garnacho-Montero J,Rello J,pH1N1 GTEI\/SEMICYUC.

更新日期：2012-07-01 00:00:00

abstract：:The process of surgical decision making is based on both general principles that are amenable to evaluation using rigorous techniques of clinical research and the intangible element of surgical judgment that seeks to apply those principles to the care of an individual patient. The role of surgical judgment is inescapa...

journal_title：Intensive care medicine

authors： Jimenez MF,Marshall JC,International Sepsis Forum.

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:To study the pattern of lung emptying and expiratory resistance in mechanically ventilated patients with chronic obstructive pulmonary disease (COPD). DESIGN:A prospective physiological study. SETTING:A 12-bed Intensive Care Unit. PATIENTS:Ten patients with acute exacerbation of COPD. INTERVENTIONS:At th...

journal_title：Intensive care medicine

authors： Kondili E,Alexopoulou C,Prinianakis G,Xirouchaki N,Georgopoulos D

更新日期：2004-07-01 00:00:00

abstract：:A 65-year-old man developed postsurgical septic shock, unresponsive to plasma volume expansion and administration of dopamine and dobutamine. A continuous norepinephrine infusion was then started and the dose increased to 0.62 micrograms.kg-1.min-1 until the mean arterial pressure was 70 mmHg. Prior to and during the ...

journal_title：Intensive care medicine

authors： Bouffard Y,Tissot S,Viale JP,Delafosse B,Annat G,Bachmann P,Motin J

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:To determine: (1) the proportion of small (<5 mm) or thrombosed internal jugular veins (IJV) and femoral veins (FV) in which catheter placement would be difficult without ultrasound guidance; (2) which position increases central vein sizes and may facilitate cannulation of these vessels. DESIGN:Prospective s...

journal_title：Intensive care medicine

authors： Samy Modeliar S,Sevestre MA,de Cagny B,Slama M

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between cytokines and the inflammatory responses in patients with out-of-hospital cardiac arrest, we examined the changes of cytokines as well as alterations in the markers of neutrophil activation, platelet and endothelial activation, and endothelial injury. DESIGN:Prospectiv...

journal_title：Intensive care medicine

authors： Gando S,Nanzaki S,Morimoto Y,Kobayashi S,Kemmotsu O

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:There are a number of potential etiologies of severe bleeding encountered in the intensive care unit. Although rare, acquired hemophilia is one such etiology that often presents with major bleeding requiring intensive care. Despite the introduction of effective treatments, the reported mortality rate of patie...

journal_title：Intensive care medicine

authors： Shander A,Walsh CE,Cromwell C

更新日期：2011-08-01 00:00:00

abstract：:A young woman with long-standing systemic lupus erythematosus and rheumatic fever presented with deteriorating renal function. She had severe gastritis treated with cimetidine and received methylprednisolone when her blood cultures were repeatedly negative. She developed spontaneous bruising and bleeding from venepunc...

journal_title：Intensive care medicine

authors： Bloxham CA,Carr S,Ryan DW,Kesteven PJ,Bexton RS,Griffiths ID,Richards J

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:The objective was to identify factors associated with thrombocytopenia and to assess to what extent thrombocytopenia increases bleeding complications in liver transplant patients. DESIGN:Retrospective study. SETTING:Surgical intensive care unit in a university hospital. PATIENTS:One hundred and sixty-one p...

journal_title：Intensive care medicine

authors： Ben Hamida C,Lauzet JY,Rézaiguia-Delclaux S,Duvoux C,Cherqui D,Duvaldestin P,Stéphan F

更新日期：2003-05-01 00:00:00

abstract：:Two patients with severe hepatic and renal failure underwent emergency hepatic retransplantation (2nd and 6th day after transplantation). Continuous arteriovenous haemodialysis was begun before surgery and successfully performed, without any incident, during the retransplantation with a biospal (SCU/CAVH AN 69 S) devi...

journal_title：Intensive care medicine

authors： Salord F,Bailly MP,Gaussorgues P,Workineh S,Pouyet M,Robert D

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:To describe a real-time ultrasound sign, the visualization of the cavity and the walls of the maxillary sinus ("sinusogram"), and to assess its correlation with total opacity of the sinus. DESIGN:Prospective clinical study. SETTING:The medical ICU of a university-affiliated hospital. PATIENTS:The significa...

journal_title：Intensive care medicine

authors： Lichtenstein D,Biderman P,Mezière G,Gepner A

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:To present our observation of the development of a rare nail deformity in the prolonged course of disease of a critically ill patient with a pulmonary abscess. DESIGN:Case report. SETTING:Tertiary referral, 16-bed, level I surgical ICU in an academic hospital. PATIENT:A 48-year-old Caucasian male was treat...

journal_title：Intensive care medicine

authors： Wester JP,van Eps RS,Stouthamer A,Girbes AR

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Peripherally inserted central venous catheters (PICC) have been proposed as an alternative to central venous catheters (CVC). The aim of this study was to determine the thrombosis rate in relation to PICC placement in patients discharged from the intensive care unit (ICU). METHODS:Data of patients admitted ...

journal_title：Intensive care medicine

authors： Bonizzoli M,Batacchi S,Cianchi G,Zagli G,Lapi F,Tucci V,Martini G,Di Valvasone S,Peris A

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Endotracheal suctioning can cause alveolar collapse and impede ventilation. One reason is the gas flow through a single-lumen endotracheal tube (ETT) provoking a gradient between airway opening and tracheal (P(tr)) pressures. Separately extending the patient tubing limbs of a suitable ventilator into the trac...

journal_title：Intensive care medicine

authors： Reissmann H,Böhm SH,Suárez-Sipmann F,Tusman G,Buschmann C,Maisch S,Pesch T,Thamm O,Plümers C,Schulte am Esch J,Hedenstierna G

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To determine if the plasma levels of three endothelial-specific proteins, von Willebrand factor (vWF), tissue factor pathway inhibitor (TFPI) and thrombomodulin (TM) may be useful in predicting the development of acute respiratory distress syndrome (ARDS). DESIGN:Blood samples were obtained from normal healt...

journal_title：Intensive care medicine

authors： Bajaj MS,Tricomi SM

更新日期：1999-11-01 00:00:00

abstract：:Nine patients hospitalized for tetanus were studied under the same protocol which included two haemodynamic studies with a preload trial (PLT). The first being made during therapy (diazepam barbiturate association), on the sixth day of hospitalisation, and the second one after recovery. The comparison of the results s...

journal_title：Intensive care medicine

authors： Desjars P,Pinaud M,Baron D,Rodineau P,Nicolas R

更新日期：1978-07-01 00:00:00

abstract：PURPOSE:To provide evidence-based guidelines for early enteral nutrition (EEN) during critical illness. METHODS:We aimed to compare EEN vs. early parenteral nutrition (PN) and vs. delayed EN. We defined "early" EN as EN started within 48 h independent of type or amount. We listed, a priori, conditions in which EN is o...

journal_title：Intensive care medicine

authors： Reintam Blaser A,Starkopf J,Alhazzani W,Berger MM,Casaer MP,Deane AM,Fruhwald S,Hiesmayr M,Ichai C,Jakob SM,Loudet CI,Malbrain ML,Montejo González JC,Paugam-Burtz C,Poeze M,Preiser JC,Singer P,van Zanten AR,De Waele J

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:It remains uncertain why immunocompetent patients with bacterial community-acquired pneumonia (CAP) die, in spite of adequate antibiotics. METHODS:This is a secondary analysis of the CAPUCI database which was a prospective observational multicentre study. Two hundred and twelve immunocompetent patients admi...

journal_title：Intensive care medicine

authors： Rodriguez A,Lisboa T,Blot S,Martin-Loeches I,Solé-Violan J,De Mendoza D,Rello J,Community-Acquired Pneumonia Intensive Care Units (CAPUCI) Study Investigators.

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:The intravenous fluid 6% hydroxyethyl starch (130/0.4) (6% HES 130/0.4) is used widely for resuscitation but there is limited information on its efficacy and safety. A large-scale multi-centre randomised controlled trial (CHEST) in critically ill patients is currently underway comparing fluid resuscitation with...

journal_title：Intensive care medicine

authors： Crystalloid versus Hydroxyethyl Starch Trial (CHEST) Management Committee.

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To determine the cell content and purity of Ficoll-separated peripheral blood mononuclear cells and granulocyte isolates in sepsis patients compared to healthy controls. DESIGN AND SETTING:Prospective study in the adult and pediatric intensive care departments of the Erasmus University Medical Center in the ...

journal_title：Intensive care medicine

authors： van den Akker EL,Baan CC,van den Berg B,Russcher H,Joosten K,Hokken-Koelega AC,Lamberts SW,Koper JW

更新日期：2008-05-01 00:00:00