The effects of norepinephrine infusion on oxygen consumption in a patient with septic shock.

Abstract:

:A 65-year-old man developed postsurgical septic shock, unresponsive to plasma volume expansion and administration of dopamine and dobutamine. A continuous norepinephrine infusion was then started and the dose increased to 0.62 micrograms.kg-1.min-1 until the mean arterial pressure was 70 mmHg. Prior to and during the norepinephrine infusion, oxygen consumption was continuously measured with a mass spectrometer system. There was a parallel increase in mean arterial pressure and oxygen consumption (+ 35%). There was also an increase in cardiac index and oxygen delivery. Systemic vascular resistance was only transiently increased. In this case with septic shock, norepinephrine infusion improved hemodynamic variables with an associated increase in oxygen consumption.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Bouffard Y,Tissot S,Viale JP,Delafosse B,Annat G,Bachmann P,Motin J

doi

10.1007/BF02575309

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

133-4

issue

2

eissn

0342-4642

issn

1432-1238

journal_volume

16

pub_type

杂志文章
  • Ultrasound-guided arterial catheterization: a narrative review.

    abstract::Arterial catheterization is the second most common invasive procedure performed in the intensive care unit. Despite the ubiquity of the procedure, complications including failure to place the catheter occur. While many clinicians are familiar with the use of ultrasound (US) guidance to decrease complication rates of c...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-009-1699-6

    authors: Shiloh AL,Eisen LA

    更新日期:2010-02-01 00:00:00

  • Preliminary results on nursing workload in a dedicated weaning center.

    abstract:OBJECTIVE:To evaluate the nursing time required for difficult-to-wean patients in a dedicated weaning center (WC) and to examine the correlation of the nursing time with nursing workload (NW) scores and with clinical severity and dependency. SETTING:Four-bed WC of a pulmonary rehabilitation department. INTERVENTION:N...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340051249

    authors: Vitacca M,Clini E,Porta R,Ambrosino N

    更新日期:2000-06-01 00:00:00

  • Influence of cardiac output on thermal-dye extravascular lung water (EVLW) in cardiac patients.

    abstract::The influence of varying cardiac output (CO) on thermal-dye extravascular lung water (EVLW) was investigated in a total of 40 cardiac surgery patients before the onset of the operation. EVLW was measured by means of the double indicator dilution technique with indocyanine green as the non-diffusible indicator and a mi...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF00255785

    authors: Boldt J,Kling D,von Bormann B,Scheld HH,Hempelmann G

    更新日期:1987-01-01 00:00:00

  • Is research from databases reliable? Not sure.

    abstract:: ...

    journal_title:Intensive care medicine

    pub_type: 评论,社论

    doi:10.1007/s00134-018-5498-9

    authors: Varkila MRJ,Cremer OL

    更新日期:2019-01-01 00:00:00

  • Erythromycin versus metoclopramide for post-pyloric spiral nasoenteric tube placement: a randomized non-inferiority trial.

    abstract:PURPOSE:To determine whether erythromycin is non-inferior to metoclopramide in facilitating post-pyloric placement of self-propelled spiral nasoenteric tubes (NETs) in critically ill patients. METHODS:A prospective, multicenter, open-label, parallel, and non-inferiority randomized controlled trial was conducted compar...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s00134-018-5466-4

    authors: Hu B,Ouyang X,Lei L,Sun C,Chi R,Guo J,Guo W,Zhang Y,Li Y,Huang D,Sun H,Nie Z,Yu J,Zhou Y,Wang H,Zhang J,Chen C

    更新日期:2018-12-01 00:00:00

  • Nine equivalents of nursing manpower use score (NEMS).

    abstract:OBJECTIVES:To develop a simplified Therapeutic Intervention Scoring System (TISS) based on the TISS-28 items and to validate the new score in an independent database. DESIGN:Retrospective statistical analysis of a database and a prospective multicentre study. SETTING:Development in the database of the Foundation for ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340050406

    authors: Reis Miranda D,Moreno R,Iapichino G

    更新日期:1997-07-01 00:00:00

  • Middle cerebral artery flow velocity decreases and electroencephalogram (EEG) changes occur as acute hypercapnia reverses.

    abstract:OBJECTIVE:To define the changes in middle cerebral artery flow velocity (Vmca) and the electroencephalogram (EEG) during rapid reduction in arterial carbon dioxide (PCO2) from acute hypercapnia. DESIGN. Human volunteer study. SETTING:University-affiliated hospital experimental laboratory. PARTICIPANTS:Nine healthy vo...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-003-1917-6

    authors: Halpern P,Neufeld MY,Sade K,Silbiger A,Szold O,Bornstein NM,Sorkine P

    更新日期:2003-10-01 00:00:00

  • Non-operative management of gastric perforation secondary to cardiopulmonary resuscitation.

    abstract::We report the case of a 72-year-old male who suffered a cardiac arrest during an early positive treadmill stress test. After successful resuscitation the patient had evidence of a gastric perforation. Because of his hemodynamic stability, lack of peritoneal signs, and prohibitively high surgical risk, a non-operative ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF01710656

    authors: Low LL,Ripple GR,Bruderer BP,Harrington GR

    更新日期:1994-07-01 00:00:00

  • Inhalation of NO during myocardial ischemia reduces infarct size and improves cardiac function.

    abstract:PURPOSE:Bioactive NO carriers in circulating blood formed during NO inhalation selectively distribute blood flow to areas in need, and may thus improve collateral perfusion to the area-at-risk in acute myocardial infarction (AMI). Here, we tested the hypothesis that NO inhalation during the ischemic phase of AMI may im...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-012-2605-1

    authors: Neye N,Enigk F,Shiva S,Habazettl H,Plesnila N,Kuppe H,Gladwin MT,Kuebler WM

    更新日期:2012-08-01 00:00:00

  • Prognostic evaluation in meningococcal disease. A retrospective study of 115 cases.

    abstract::A retrospective study of the medical records of 115 consecutive cases of meningococcal disease with 11 fatalities was carried out in order to evaluate the power of 15 clinical and laboratory variables available on admission in predicting a fatal outcome. On linear discriminant analysis, six variables showed a signific...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF00261740

    authors: Gårdlund B

    更新日期:1986-01-01 00:00:00

  • Effects of controlled mechanical ventilation on respiratory muscle contractile properties in rabbits.

    abstract:OBJECTIVE:We examined in rabbits the effects of more than 48 h of mechanical ventilation on the contractile properties and fiber type adaptations of the respiratory muscles. DESIGN AND SETTING:Experimental prospective study in a university laboratory. ANIMALS AND INTERVENTIONS:Nineteen rabbits were randomly allocated...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-002-1548-3

    authors: Capdevila X,Lopez S,Bernard N,Rabischong E,Ramonatxo M,Martinazzo G,Prefaut C

    更新日期:2003-01-01 00:00:00

  • Heart rate reduction with esmolol is associated with improved arterial elastance in patients with septic shock: a prospective observational study.

    abstract:PURPOSE:Ventricular-arterial (V-A) decoupling decreases myocardial efficiency and is exacerbated by tachycardia that increases static arterial elastance (Ea). We thus investigated the effects of heart rate (HR) reduction on Ea in septic shock patients using the beta-blocker esmolol. We hypothesized that esmolol improve...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-016-4351-2

    authors: Morelli A,Singer M,Ranieri VM,D'Egidio A,Mascia L,Orecchioni A,Piscioneri F,Guarracino F,Greco E,Peruzzi M,Biondi-Zoccai G,Frati G,Romano SM

    更新日期:2016-10-01 00:00:00

  • Obesity in the critically ill: a narrative review.

    abstract::The World Health Organization defines overweight and obesity as the condition where excess or abnormal fat accumulation increases risks to health. The prevalence of obesity is increasing worldwide and is around 20% in ICU patients. Adipose tissue is highly metabolically active, and especially visceral adipose tissue h...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-019-05594-1

    authors: Schetz M,De Jong A,Deane AM,Druml W,Hemelaar P,Pelosi P,Pickkers P,Reintam-Blaser A,Roberts J,Sakr Y,Jaber S

    更新日期:2019-06-01 00:00:00

  • Effects of early treatment with immunoglobulin on critical illness polyneuropathy following multiple organ failure and gram-negative sepsis.

    abstract:OBJECTIVE:The evaluation of incidences and relating factors of severe persisting critical illness polyneuropathy (CIP) in survivors of multiple organ failure (MOF). DESIGN:Prospective study with an entry period of 24 months. Electrophysiological studies for the diagnosis of CIP were performed 1 or 2 days before the pa...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340050471

    authors: Mohr M,Englisch L,Roth A,Burchardi H,Zielmann S

    更新日期:1997-11-01 00:00:00

  • Hyperglycaemia and mortality in critically ill patients. A prospective study.

    abstract:OBJECTIVE:To describe hyperglycaemia as a possible marker of morbidity and mortality in critically ill medical and surgical patients admitted to a multidisciplinary ICU. DESIGN:Prospective cohort study. SETTING:A 13-bed non-cardiac multidisciplinary ICU in a university hospital. PATIENTS AND PARTICIPANTS:Adult patie...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-004-2325-2

    authors: Christiansen C,Toft P,Jørgensen HS,Andersen SK,Tønnesen E

    更新日期:2004-08-01 00:00:00

  • Chapter 5. Essential equipment, pharmaceuticals and supplies. Recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza epidemic or mass disaster.

    abstract:PURPOSE:To provide recommendations and standard operating procedures for intensive care unit and hospital preparations for an influenza pandemic or mass disaster with a specific focus on essential equipment, pharmaceuticals and supplies. METHODS:Based on a literature review and expert opinion, a Delphi process was use...

    journal_title:Intensive care medicine

    pub_type: 指南,杂志文章

    doi:10.1007/s00134-010-1763-2

    authors: Sprung CL,Kesecioglu J,European Society of Intensive Care Medicine's Task Force for intensive care unit triage during an influenza epidemic or mass disaster.

    更新日期:2010-04-01 00:00:00

  • Audit of intensive care: a 30 month experience using the Apache II severity of disease classification system.

    abstract::608 patients admitted to a general Intensive Care Unit (ICU) over a 30 month period were analyzed according to the Apache II Severity of Disease Classification System on day one of admission. Hospital outcome details were available on 583 patients in the series. The mean Apache II scores for survivors (396) and non-su...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF00263531

    authors: Jacobs S,Chang RW,Lee B,Lee B

    更新日期:1988-01-01 00:00:00

  • Cardiac arrest due to oral potassium intake.

    abstract::A 29-year-old woman suffered a cardiac arrest, due to profound hyperkalaemia, caused by the use of a potassium-containing salt substitute. She was resuscitated, but post-hypoxic brain damage occurred. Some of the sparse literature is reviewed. ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/BF00255641

    authors: Schim van der Loeff HJ,Strack van Schijndel RJ,Thijs LG

    更新日期:1988-01-01 00:00:00

  • The influence of infection sites on development and mortality of ARDS.

    abstract:OBJECTIVE:Infection is the most frequent cause of acute respiratory distress syndrome (ARDS). However, little is known about the influence of infection sites on ARDS. This study aimed to assess the associations of infection sites with ARDS development and mortality in critically ill infected patients. DESIGN:Prospecti...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-010-1851-3

    authors: Sheu CC,Gong MN,Zhai R,Bajwa EK,Chen F,Thompson BT,Christiani DC

    更新日期:2010-06-01 00:00:00

  • Measurement of lung volume in mechanically ventilated monkeys with an ultrasonic flow meter and the nitrogen washout method.

    abstract:OBJECTIVE:Measurement of functional residual capacity (FRC) during mechanical ventilation is important to standardise respiratory system compliance and adjust the ventilator settings to optimise lung recruitment. In the present study we compared three methods to measure FRC. DESIGN:The bias flow nitrogen washout techn...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-003-2028-0

    authors: Schibler A,Hammer J,Isler R,Buess C,Newth CJ

    更新日期:2004-01-01 00:00:00

  • Cytokeratin 19 fragments in patients with acute lung injury: a preliminary observation.

    abstract:OBJECTIVE:Cytokeratin 19 (CK19) is a specific cytoskeletal structure for alveolar epithelium. We hypothesized that the levels of CK19 fragments in bronchoalveolar lavage (BAL) fluid could serve as an index of epithelial injury and as a prognosis marker in patients with acute lung injury (ALI) or acute respiratory distr...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-006-0124-7

    authors: Stern JB,Paugam C,Validire P,Adle-Biassette H,Jaffré S,Dehoux M,Crestani B

    更新日期:2006-06-01 00:00:00

  • Ultrasound evaluation of central veinsin the intensive care unit:effects of dynamic manoeuvres.

    abstract:OBJECTIVE:To determine: (1) the proportion of small (<5 mm) or thrombosed internal jugular veins (IJV) and femoral veins (FV) in which catheter placement would be difficult without ultrasound guidance; (2) which position increases central vein sizes and may facilitate cannulation of these vessels. DESIGN:Prospective s...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-007-0875-9

    authors: Samy Modeliar S,Sevestre MA,de Cagny B,Slama M

    更新日期:2008-02-01 00:00:00

  • Infection control practices in intensive care units of 14 European countries. The EURO.NIS Study Group.

    abstract:OBJECTIVE:To evaluate compliance with recommended patient-care practices for the prevention of hospital-acquired infections (HAI) in the intensive care unit (ICU). DESIGN:European descriptive survey by questionnaire mailed to all the directors of ICUs. PATIENTS AND PARTICIPANTS:A total of 1642 general ICUs with more ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF02044110

    authors: Moro ML,Jepsen OB

    更新日期:1996-09-01 00:00:00

  • Intravenous fish oil blunts the physiological response to endotoxin in healthy subjects.

    abstract:OBJECTIVE:To assess the effects of intravenous fish oil fat emulsion on the metabolic alterations induced by lipopolysaccharide (LPS) challenge in healthy volunteers. DESIGN:Two groups of eight healthy subjects were randomized to receive either two pharmacological doses of intravenous FO fat emulsion or no treatment. ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00134-007-0591-5

    authors: Pluess TT,Hayoz D,Berger MM,Tappy L,Revelly JP,Michaeli B,Carpentier YA,Chioléro RL

    更新日期:2007-05-01 00:00:00

  • Influence of SIMV plus inspiratory pressure support on VA/Q distributions during postoperative weaning.

    abstract::Since the introduction of synchronized intermittent mandatory ventilation (SIMV) several advantages have been attributed to this ventilatory mode, one of them being a more homogeneous distribution of ventilation and perfusion than during controlled mechanical ventilation (CMV). Up to now no data are available to confi...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF01704716

    authors: Santak B,Radermacher P,Sandmann W,Falke KJ

    更新日期:1991-01-01 00:00:00

  • Acute heart failure and cardiogenic shock: a multidisciplinary practical guidance.

    abstract:PURPOSE:Acute heart failure (AHF) causes high burden of mortality, morbidity, and repeated hospitalizations worldwide. This guidance paper describes the tailored treatment approaches of different clinical scenarios of AHF and CS, focusing on the needs of professionals working in intensive care settings. RESULTS:Tissue...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-015-4041-5

    authors: Mebazaa A,Tolppanen H,Mueller C,Lassus J,DiSomma S,Baksyte G,Cecconi M,Choi DJ,Cohen Solal A,Christ M,Masip J,Arrigo M,Nouira S,Ojji D,Peacock F,Richards M,Sato N,Sliwa K,Spinar J,Thiele H,Yilmaz MB,Januzzi J

    更新日期:2016-02-01 00:00:00

  • Time course of activated coagulation time at various sites during continuous haemodiafiltration using nafamostat mesilate.

    abstract:OBJECTIVE:To determine the adequate site of activated coagulation time (ACT) measurement during continuous haemodiafiltration (CHDF) using nafamostat mesilate. DESIGN:Prospective, consecutive, clinical study. SETTING:An intensive care unit of a general hospital. PATIENTS:Ten patients with acute organ failure includi...

    journal_title:Intensive care medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/s001340050892

    authors: Hu ZJ,Iwama H,Suzuki R,Kobayashi S,Akutsu I

    更新日期:1999-05-01 00:00:00

  • The epidemiology of infections in intensive care units.

    abstract::This report identifies some of the risk factors underlying the acquisition of hospital infections in patients admitted to Intensive Care Units (ICUs). Infection rates vary in different institutes and in different types of ICUs. Patients are particularly prone to septicaemia and respiratory infections and the underlyin...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/BF01709700

    authors: Emmerson AM

    更新日期:1990-01-01 00:00:00

  • Continuous cardiac output monitoring after cardiopulmonary bypass: a comparison with bolus thermodilution measurement.

    abstract:OBJECTIVE:The interchangeability of continuous measurement of cardiac output (CO) with the traditional bolus method in patients after cardiopulmonary bypass (CPB) is uncertain. DESIGN:Prospective observational clinical study. SETTING:A 20-bed surgical ICU at a university hospital. PATIENTS:Fourteen deeply sedated, v...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-006-0161-2

    authors: Bendjelid K,Schütz N,Suter PM,Romand JA

    更新日期:2006-06-01 00:00:00

  • Treatment of hypertensive emergency. Comparison of a new dosage form of the calcium antagonist nitrendipine with nifedipine capsules.

    abstract:OBJECTIVE:To present the efficacy and tolerability of a new oral dosage form of the calcium antagonist nitrendipine compared to nifedipine capsules in patients with hypertensive emergency. DESIGN:Multicenter randomized double blind clinical study. SETTING:23 study centres (hospitals) in Germany. PATIENTS:161 patient...

    journal_title:Intensive care medicine

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1007/BF01708963

    authors: Rohr G,Reimnitz P,Blanke P

    更新日期:1994-01-01 00:00:00