Inhalation of NO during myocardial ischemia reduces infarct size and improves cardiac function.

abstract：OBJECTIVE:To investigate the effects of some acid-base abnormalities on blood capacity of transporting CO(2). DESIGN:Prospective study. SETTING:General and Cardiosurgical ICUs of a University hospital. PATIENTS:Six groups of ten patients characterized by: metabolic alkalosis; respiratory alkalosis; absence of acid-b...

journal_title：Intensive care medicine

authors： Cavaliere F,Antonelli M,Arcangeli A,Conti G,Pennisi MA,Proietti R

更新日期：2002-05-01 00:00:00

abstract：:In severe status asthmaticus basic medical treatment often fails to improve the patient's condition. Mechanical ventilation in this situation is associated with a high incidence of serious complications. After the bronchodilating effect of moderate-dose magnesium sulfate in asthmatic patients had been demonstrated in ...

journal_title：Intensive care medicine

authors： Sydow M,Crozier TA,Zielmann S,Radke J,Burchardi H

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:Polymyxin B-immobilized hemoperfusion (PMX-HP) is an adjuvant therapy for sepsis or septic shock that clears circulating endotoxin. Prior trials have shown that PMX-HP improves surrogate endpoints. We aimed to conduct an evidence synthesis to evaluate the efficacy and safety of PMX-HP in critically ill adult pa...

journal_title：Intensive care medicine

authors： Fujii T,Ganeko R,Kataoka Y,Furukawa TA,Featherstone R,Doi K,Vincent JL,Pasero D,Robert R,Ronco C,Bagshaw SM

更新日期：2018-02-01 00:00:00

abstract：:Cardiac arrhythmias and circulatory collapse account for the high mortality reported after severe chloroquine poisoning. We have recently observed a 17-year-old man who ingested an 8 g chloroquine overdose. Cardiac arrest occurred within 1 h. Cardiogenic shock was refractory to epinephrine, dopamine and molar sodium l...

journal_title：Intensive care medicine

authors： Hantson P,Ronveau JL,De Coninck B,Horn JL,Mahieu P,Hassoun A

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the sensitivity, specificity and overall accuracy of a model based on the presence or absence of organ dysfunctions and/or infection (ODIN) to predict the outcome for intensive care unit patients. DESIGN:Prospective study. SETTING:General intensive care unit in a university teaching hospital. P...

journal_title：Intensive care medicine

authors： Fagon JY,Chastre J,Novara A,Medioni P,Gibert C

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:Invasive candidiasis (IC) outcomes in intensive care units (ICUs) could be improved by the early administration of antifungals. The Candida Score (CS) prediction rule has been proposed for the selection of patients who could develop IC. Procalcitonin (PCT) levels allow prompt identification of sepsis, but the...

journal_title：Intensive care medicine

authors： Charles PE,Castro C,Ruiz-Santana S,León C,Saavedra P,Martín E

更新日期：2009-12-01 00:00:00

abstract：:We evaluated the effect of a cimetidine continuous infusion (2 g in 24 h) on the intragastric pH of 16 critically ill patients (11 men, 5 women, mean age 45 years). During the 24 h pre-trial period and the subsequent 24 h cimetidine infusion, an intragastric combined electrode was placed in the fundus and the pH recor...

journal_title：Intensive care medicine

authors： Tomé G,Fiasse R,Reynaert M,Mahieu P,Hanssens F

更新日期：1988-01-01 00:00:00

abstract：:Achievement of a mean blood pressure (MBP) target is one of the hemodynamic goals to ensure an adequate blood perfusion pressure in critically ill patients. Arterial catheter allows for a continuous and precise monitoring of arterial pressure signal. In addition to giving a precise MBP monitoring, analysis of the bloo...

journal_title：Intensive care medicine

authors： Augusto JF,Teboul JL,Radermacher P,Asfar P

更新日期：2011-03-01 00:00:00

abstract：:The arterial oxygen and carbon dioxide tensions, pulmonary and systemic haemodynamics and pulmonary shunting and mechanics were measured during the first 30 min after intravenous labetalol administration. Thirty patients, recovering in the intensive care unit after neurosurgical interventions were randomly divided in ...

journal_title：Intensive care medicine

authors： De Hert SG,Heytens LG,De Jongh RG,Vercauteren MP,Boeckx EA,Adriaensen HF

更新日期：1988-01-01 00:00:00

abstract：:In critically ill patients, it is frequently challenging to identify who will benefit from admission to the intensive care unit and life-sustaining interventions when the chances of a meaningful outcome are unclear. In addition, the acute illness not only affects the patients but also family members or surrogates who ...

journal_title：Intensive care medicine

authors： Vink EE,Azoulay E,Caplan A,Kompanje EJO,Bakker J

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that levosimendan increases systemic and intestinal oxygen delivery (DO(2)) and prevents intramucosal acidosis in septic shock. DESIGN:Prospective, controlled experimental study. SETTING:University-based research laboratory. SUBJECTS:Nineteen anesthetized, mechanically ventilated she...

journal_title：Intensive care medicine

authors： Dubin A,Murias G,Sottile JP,Pozo MO,Barán M,Edul VS,Canales HS,Etcheverry G,Maskin B,Estenssoro E

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:To examine the usefulness of preload indices obtained by transoesophageal echocardiography (TOE) for estimating stroke volume at various levels of cardiac index. DESIGN:Prospective clinical study. SETTING:Intensive care unit with surgical patients. PATIENTS:16 ventilated patients monitored via Swan-Ganz ca...

journal_title：Intensive care medicine

authors： Greim CA,Roewer N,Apfel C,Laux G,Schulte am Esch J

更新日期：1997-04-01 00:00:00

abstract：PURPOSE:We evaluated whether oscillatory compliance (C(X5)) measured by forced oscillation technique (FOT) at 5 Hz may be useful for positive end-expiratory pressure (PEEP) optimisation. METHODS:We studied seven pigs in which lung injury was induced by broncho-alveolar lavage. The animals were ventilated in volume con...

journal_title：Intensive care medicine

authors： Dellacà RL,Zannin E,Kostic P,Olerud MA,Pompilio PP,Hedenstierna G,Pedotti A,Frykholm P

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:To assess the effects of alveolar recruitment maneuvers (ARMs) on clinical outcomes in patients with acute respiratory distress syndrome (ARDS). METHODS:We conducted a search of the MEDLINE, EMBASE, LILACS, CINAHL, CENTRAL, Scopus, and Web of Science (from inception to July 2014) databases for all (i.e. no lan...

journal_title：Intensive care medicine

authors： Suzumura EA,Figueiró M,Normilio-Silva K,Laranjeira L,Oliveira C,Buehler AM,Bugano D,Passos Amato MB,Ribeiro Carvalho CR,Berwanger O,Cavalcanti AB

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To analyze the effect of endothelin-1 on pulmonary arterial and venous contractile force in vitro and on up- and downstream pulmonary vascular resistance in vivo under sham and endotoxemic conditions in pigs. MATERIALS AND METHODS:In vitro: paired preparations of pulmonary arteries and veins were mounted in ...

journal_title：Intensive care medicine

authors： Rossi P,Persson B,Boels PJ,Arner A,Weitzberg E,Oldner A

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:An International Consensus Conference proposed classifying weaning into simple, difficult, and prolonged weaning. However, the usefulness of this classification in a respiratory intensive care unit (ICU) is unknown. The aims of the study were: (1) to compare the clinical characteristics and outcomes of patients...

journal_title：Intensive care medicine

authors： Sellares J,Ferrer M,Cano E,Loureiro H,Valencia M,Torres A

更新日期：2011-05-01 00:00:00

abstract：:Myxoedema coma is a medical emergency with high mortality. In this study, clinical response and plasma variations of thyroid hormones were analysed in 7 patients, 6 presenting with myxoedema coma and one with myxoedema ileus. These patients were treated with intravenous or oral l-thyroxine (l-T4). 1000 mu l-T4 iv were...

journal_title：Intensive care medicine

authors： Arlot S,Debussche X,Lalau JD,Mesmacque A,Tolani M,Quichaud J,Fournier A

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:To determine whether erythromycin is non-inferior to metoclopramide in facilitating post-pyloric placement of self-propelled spiral nasoenteric tubes (NETs) in critically ill patients. METHODS:A prospective, multicenter, open-label, parallel, and non-inferiority randomized controlled trial was conducted compar...

journal_title：Intensive care medicine

authors： Hu B,Ouyang X,Lei L,Sun C,Chi R,Guo J,Guo W,Zhang Y,Li Y,Huang D,Sun H,Nie Z,Yu J,Zhou Y,Wang H,Zhang J,Chen C

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:We assessed the methodological trial quality of individual randomized controlled studies on chlorhexidine silver sulfadiazine impregnated catheters and the effect on catheter-related infection (CRI). DESIGN:Only the studies identified in the Medline database from 1966 to December 2001 were considered, abstra...

journal_title：Intensive care medicine

authors： Geffers C,Zuschneid I,Eckmanns T,Rüden H,Gastmeier P

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVES:To investigate at what time the peak level should be determined under conventional thrice daily (t.i.d.) administration of the aminoglycoside netilmicin and to study its serum concentrations under once daily (od) treatment to define the required daily dose and to gain information about convenient drug monito...

journal_title：Intensive care medicine

authors： Konrad F,Wagner R,Neumeister B,Rommel H,Georgieff M

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of prone positioning on systemic hemodynamics, intra-abdominal pressure (IAP), plasma disappearance rate of indocyanine green (PDR(ICG)), and gastric intramucosal to arterial PCO2 difference (Pi-aCO2). DESIGN AND SETTING:Prospective randomized study in the intensive care unit of a ...

journal_title：Intensive care medicine

authors： Hering R,Vorwerk R,Wrigge H,Zinserling J,Schröder S,von Spiegel T,Hoeft A,Putensen C

更新日期：2002-01-01 00:00:00

abstract：:We report a case of fatal septic shock, with hyperlactatemia and blood cultures positive for Streptococcus pneumoniae, in a 70-year-old patient. On two occasions (5 days, and 2 days before the patient's death), the relationship between oxygen delivery (DO2) and consumption (VO2) was examined in conjunction with two pr...

journal_title：Intensive care medicine

authors： Gallet D,Goudable J,Vedrinne JM,Viale JP,Annat G

更新日期：1997-01-01 00:00:00

abstract：:Activation of the complement system within the lung can lead to acute pulmonary damage and dysfunction. Based on a variety of experimental models it is now apparent that lung injury is related to complement-induced generation of oxygen derived free radicals from neutrophils and from macrophages. In addition to the oxy...

journal_title：Intensive care medicine

authors： Ward PA,Johnson KJ,Till GO

更新日期：1986-01-01 00:00:00

abstract：:There has been little research on smoking cessation after critical illness. Smokers make up a high percentage of patients admitted to intensive care (ICU) and stopping smoking is one message that should be clearly given to recovering patients. The recovery period provides an important opportunity for patients to quit ...

journal_title：Intensive care medicine

authors： Jones C,Griffiths RD,Skirrow P,Humphris G

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:Evaluating the prevalence, risk factors and prevention of pressure ulcers in Dutch intensive care units (ICUs). DESIGN:Cross-sectional design. SETTING:ICUs of acute care hospitals that participated in the 1998 and 1999 national prevalence surveys. Data were collected on 1 day in each year. PATIENTS:Eight h...

journal_title：Intensive care medicine

authors： Bours GJ,De Laat E,Halfens RJ,Lubbers M

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:To compare the effectiveness of 70-mg and 200-mg doses of intravenous erythromycin in improving gastric emptying in critically ill patients. DESIGN:Gastric emptying was measured on consecutive days; day 1 (pre-treatment), day 2 (post-treatment) after an intravenous infusion of either 70 or 200 mg erythromyci...

journal_title：Intensive care medicine

authors： Ritz MA,Chapman MJ,Fraser RJ,Finnis ME,Butler RN,Cmielewski P,Davidson GP,Rea D

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between cytokines and the inflammatory responses in patients with out-of-hospital cardiac arrest, we examined the changes of cytokines as well as alterations in the markers of neutrophil activation, platelet and endothelial activation, and endothelial injury. DESIGN:Prospectiv...

journal_title：Intensive care medicine

authors： Gando S,Nanzaki S,Morimoto Y,Kobayashi S,Kemmotsu O

更新日期：1999-06-01 00:00:00

abstract：:Since the introduction of synchronized intermittent mandatory ventilation (SIMV) several advantages have been attributed to this ventilatory mode, one of them being a more homogeneous distribution of ventilation and perfusion than during controlled mechanical ventilation (CMV). Up to now no data are available to confi...

journal_title：Intensive care medicine

authors： Santak B,Radermacher P,Sandmann W,Falke KJ

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To obtain insight into the occurrence of brain death and the potential for brain dead and controlled non-heart-beating organ donors (CNHB) in patients with traumatic brain injury (TBI), subarachnoid haemorrhage (SAH) and intracerebral haemorrhage (ICH) in a large neurosurgical serving area (2.1 million inhabi...

journal_title：Intensive care medicine

authors： Kompanje EJO,Bakker J,Slieker FJA,IJzermans JNM,Maas AIR

更新日期：2006-02-01 00:00:00

abstract：PURPOSE:A retrieval program was developed in New South Wales (NSW), Australia to provide extracorporeal membrane oxygenation support (ECMO) for the safe transport of adults with severe, acute respiratory or cardiac failure. We describe the development and results of this program and the impact of the 2009 H1N1 epidemic...

journal_title：Intensive care medicine

authors： Forrest P,Ratchford J,Burns B,Herkes R,Jackson A,Plunkett B,Torzillo P,Nair P,Granger E,Wilson M,Pye R

更新日期：2011-05-01 00:00:00