当前位置： SCI文献检索 > INTENSIVE CARE MEDICINE期刊下所有文献 > The influence of labetalol on arterial blood gas data, pulmonary haemodynamics and pulmonary shunting.

The influence of labetalol on arterial blood gas data, pulmonary haemodynamics and pulmonary shunting.

Abstract：

:The arterial oxygen and carbon dioxide tensions, pulmonary and systemic haemodynamics and pulmonary shunting and mechanics were measured during the first 30 min after intravenous labetalol administration. Thirty patients, recovering in the intensive care unit after neurosurgical interventions were randomly divided in 2 groups of 15 patients, receiving either labetalol or placebo. In the labetalol treated group the arterial oxygen tension decreased from 553.6 +/- 16.8 to 529.3 +/- 19.8 mmHg 5 min after the injection of labetalol. A concomitant increase in arterial carbon dioxide tension from 40.1 +/- 1.1 to 45.5 +/- 1.3 mmHg was noticed. Pulmonary vascular resistance decreased from 159.6 +/- 14.7 to 116.7 +/- 11.7 dynes.sec.cm-5 and pulmonary shunting increased from 4.8% +/- 1.4% to 8.1% +/- 2.4% 5 min following injection. All these changes were statistically significant for p less than 0.01. After 30 min all values had returned to their initial level. No changes were registered in the control group. As airway resistance appeared not to be affected by the labetalol administration it may be concluded that the observed changes in blood gas data are most likely due to a transient decrease of the pulmonary vascular resistance with a concomitant increase in pulmonary shunting.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

De Hert SG,Heytens LG,De Jongh RG,Vercauteren MP,Boeckx EA,Adriaensen HF

doi

10.1007/BF00255635

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

42-5

issue

1

eissn

0342-4642

issn

1432-1238

journal_volume

15

pub_type

临床试验,杂志文章,随机对照试验

相关文献

INTENSIVE CARE MEDICINE文献大全
  • Early prediction of non-survival for patients suffering cardiac arrest--a word of caution. The Belgian Cerebral Resuscitation Study Group.

    abstract：:A total of 6178 persons with out-of-hospital (70%) and in hospital (30%) cardiac arrests from the first of January 1982 until the end of 1989 were reviewed retrospectively with respect to 4 variables, contributing to a score for specific prediction of poor prognosis (cut-off point: greater than 3 points). These includ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01706419

    authors： Martens PR,Mullie A,Buylaert W,Calle P,van Hoeyweghen R

    更新日期：1992-01-01 00:00:00

  • Inter-observer variability in APACHE II scoring: effect of strict guidelines and training.

    abstract：OBJECTIVE:To assess the effect of strict guidelines and a rigorous training program on variability in scoring the revised Acute Physiology and Chronic Health Evaluation (APACHE II). DESIGN AND SETTING:Prospective survey and intervention in the surgical ICU of a university teaching hospital. MEASUREMENTS:Seven experie...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章

    doi：10.1007/s001340101012

    authors： Polderman KH,Jorna EM,Girbes AR

    更新日期：2001-08-01 00:00:00

  • The metrics of glycaemic control in critical care.

    abstract：INTRODUCTION:Trials of tight glucose control have compared measures of central tendency, such as average blood glucose, and yielded conflicting results. Other metrics, such as standard deviation, reflect different properties of glucose control and are also associated with changes in outcome. It is possible, therefore, ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-010-2103-2

    authors： Mackenzie IM,Whitehouse T,Nightingale PG

    更新日期：2011-03-01 00:00:00

  • Disseminated zygomycosis and systemic lupus erythematosus.

    abstract：:A young woman with long-standing systemic lupus erythematosus and rheumatic fever presented with deteriorating renal function. She had severe gastritis treated with cimetidine and received methylprednisolone when her blood cultures were repeatedly negative. She developed spontaneous bruising and bleeding from venepunc...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01724803

    authors： Bloxham CA,Carr S,Ryan DW,Kesteven PJ,Bexton RS,Griffiths ID,Richards J

    更新日期：1990-01-01 00:00:00

  • The diagnostic accuracy of clinical examination for estimating cardiac index in critically ill patients: the Simple Intensive Care Studies-I.

    abstract：PURPOSE:Clinical examination is often the first step to diagnose shock and estimate cardiac index. In the Simple Intensive Care Studies-I, we assessed the association and diagnostic performance of clinical signs for estimation of cardiac index in critically ill patients. METHODS:In this prospective, single-centre coho...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-019-05527-y

    authors： Hiemstra B,Koster G,Wiersema R,Hummel YM,van der Harst P,Snieder H,Eck RJ,Kaufmann T,Scheeren TWL,Perner A,Wetterslev J,de Smet AMGA,Keus F,van der Horst ICC,SICS Study Group.

    更新日期：2019-02-01 00:00:00

  • Life-threatening hyperkalaemia following therapeutic barbiturate coma.

    abstract：OBJECTIVE:To report the occurrence of life-threatening hyperkalaemia following treatment with therapeutic thiopentone coma. SETTING:The neurosurgical intensive care units of Royal North Shore Hospital and Liverpool Hospital, Sydney, Australia. PATIENTS:Three patients treated with theraputic thiopentone coma. One pati...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-002-1399-y

    authors： Cairns CJ,Thomas B,Fletcher S,Parr MJ,Finfer SR

    更新日期：2002-09-01 00:00:00

  • Endotoxemic pulmonary hypertension is largely mediated by endothelin-induced venous constriction.

    abstract：OBJECTIVE:To analyze the effect of endothelin-1 on pulmonary arterial and venous contractile force in vitro and on up- and downstream pulmonary vascular resistance in vivo under sham and endotoxemic conditions in pigs. MATERIALS AND METHODS:In vitro: paired preparations of pulmonary arteries and veins were mounted in ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-007-0980-9

    authors： Rossi P,Persson B,Boels PJ,Arner A,Weitzberg E,Oldner A

    更新日期：2008-05-01 00:00:00

  • Correction to: COVID-19: a novel coronavirus and a novel challenge for critical care.

    abstract：:The original version of this article unfortunately contained a mistake. ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,已发布勘误

    doi：10.1007/s00134-020-06009-2

    authors： Arabi YM,Murthy S,Webb S

    更新日期：2020-05-01 00:00:00

  • Influence of parenteral fat administration on the pulmonary vascular system in man.

    abstract：:In 16 patients with multiple injuries the effect of parenteral administration of a fat emulsion on the pulmonary vascular system has been studied. Using the Hewlett Packard 5600 A Intensive Care System, which allows vital parameters to be sampled at a rate of two values per min, pulmonary artery pressure (PAP) was mon...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01699260

    authors： van Deyk K,Hempel V,Münch F,Kopp M,Graf H,Epple E

    更新日期：1983-01-01 00:00:00

  • Hypertensive crisis immediately after complete removal of phaeochromocytoma.

    abstract：:A hypertensive crisis with an arterial blood pressure of 280/180 mmHg developed immediately after an apparently successful removal of a phaeochromocytoma. The blood pressure could not be lowered by phentolamine and not until the administration of dihydralazine and furosemide was the systemic pressure normalized. In ad...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF00315379

    authors： Johansson H,Brismar B,Hedenstierna G

    更新日期：1986-01-01 00:00:00

  • A brief history of tracheostomy and tracheal intubation, from the Bronze Age to the Space Age.

    abstract：OBJECTIVE:To present a concise history of tracheostomy and tracheal intubation for the approximately forty centuries from their earliest description around 2000 BC until the middle of the twentieth century, at which time a proliferation of advances marked the beginning of the modern era of anesthesiology. DATA SOURCES...

    journal_title：Intensive care medicine

    pub_type： 历史文章,杂志文章

    doi：10.1007/s00134-007-0931-5

    authors： Szmuk P,Ezri T,Evron S,Roth Y,Katz J

    更新日期：2008-02-01 00:00:00

  • Does bronchial thermodilution allow estimation of cardiac output?

    abstract：OBJECTIVE:Transcapillary heat transfer after injections of cold saline into the right atrium generates bronchial thermodilution curves resembling those observed in the aorta. Under the assumption that no indicator is lost or gained within the pulmonary capillary bed and changes in blood temperature are instantaneously ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340050818

    authors： Loer SA,Wietasch JK,Scheeren TW

    更新日期：1999-02-01 00:00:00

  • Candida spp. airway colonization could promote antibiotic-resistant bacteria selection in patients with suspected ventilator-associated pneumonia.

    abstract：OBJECTIVE:Candida spp. airway colonization could promote development of ventilator-associated pneumonia (VAP) caused by Pseudomonas aeruginosa, a potentially multidrug-resistant (MDR) bacteria, and worsen the outcome of VAP regardless of pathogen. We therefore address the question of the risk of MDR bacteria isolation ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-012-2584-2

    authors： Hamet M,Pavon A,Dalle F,Pechinot A,Prin S,Quenot JP,Charles PE

    更新日期：2012-08-01 00:00:00

  • Systemic antibiotic treatment of nosocomial pneumonia.

    abstract：:Nosocomial pneumonia continues to represent a significant cause of morbidity and mortality in hospitalized patients. Bacteria are responsible for greater than 90% of the pneumonias, the most common isolates being aerobic Gram-negative bacilli and S. aureus. Cornerstones of treatment are intravenous antibiotics and sup...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/BF01752974

    authors： Unertl KE,Lenhart FP,Forst H,Peter K

    更新日期：1992-01-01 00:00:00

  • Effect of a 2 g cimetidine infusion on twenty-four-hour intragastric pH in critically ill patients.

    abstract：:We evaluated the effect of a cimetidine continuous infusion (2 g in 24 h) on the intragastric pH of 16 critically ill patients (11 men, 5 women, mean age 45 years). During the 24 h pre-trial period and the subsequent 24 h cimetidine infusion, an intragastric combined electrode was placed in the fundus and the pH recor...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF00262892

    authors： Tomé G,Fiasse R,Reynaert M,Mahieu P,Hanssens F

    更新日期：1988-01-01 00:00:00

  • Alternative modes of ventilation. Part I. Disadvantages of controlled mechanical ventilation: intermittent mandatory ventilation.

    abstract：:Controlled mechanical ventilation is an accepted therapy for acute respiratory failure but by virtue of the increase in intrathoracic pressure has a large number of disadvantages. It is to overcome these disadvantages that alternative modes of ventilation have been introduced. These aim to reduce the effects of abnorm...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,评审

    doi：10.1007/BF00254773

    authors： Willatts SM

    更新日期：1985-01-01 00:00:00

  • The Crystalloid versus Hydroxyethyl Starch Trial: protocol for a multi-centre randomised controlled trial of fluid resuscitation with 6% hydroxyethyl starch (130/0.4) compared to 0.9% sodium chloride (saline) in intensive care patients on mortality.

    abstract：PURPOSE:The intravenous fluid 6% hydroxyethyl starch (130/0.4) (6% HES 130/0.4) is used widely for resuscitation but there is limited information on its efficacy and safety. A large-scale multi-centre randomised controlled trial (CHEST) in critically ill patients is currently underway comparing fluid resuscitation with...

    journal_title：Intensive care medicine

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1007/s00134-010-2117-9

    authors： Crystalloid versus Hydroxyethyl Starch Trial (CHEST) Management Committee.

    更新日期：2011-05-01 00:00:00

  • Comparison of norepinephrine and dobutamine to epinephrine for hemodynamics, lactate metabolism, and gastric tonometric variables in septic shock: a prospective, randomized study.

    abstract：OBJECTIVES:To compare the effects of norepinephrine and dobutamine to epinephrine on hemodynamics, lactate metabolism, and gastric tonometric variables in hyperdynamic dopamine-resistant septic shock. DESIGN:A prospective, intervention, randomized clinical trial. SETTING:Adult medical/surgical intensive care unit in ...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/s001340050329

    authors： Levy B,Bollaert PE,Charpentier C,Nace L,Audibert G,Bauer P,Nabet P,Larcan A

    更新日期：1997-03-01 00:00:00

  • Management of severe and complicated malaria in the intensive care unit.

    abstract：:Malaria remains today one of the major health problems in the tropics with increased morbidity and mortality. The most serious complications are caused by Plasmodium falciparum, which, in contrast to the benign malarias, may progress to a life-threatening multi-system disease. Our case concerns a young woman in the 14...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340050939

    authors： Gregorakos L,Sakayianni K,Hroni D,Harizopoulou V,Georgiadou F,Adamidou M

    更新日期：1999-07-01 00:00:00

  • The calcium sensitizer levosimendan attenuates endotoxin-evoked myocardial dysfunction in isolated guinea pig hearts.

    abstract：OBJECTIVE:Sepsis-evoked myocardial dysfunction is possibly due to decreased myofilament calcium sensitivity, and a calcium sensitizer may thus specifically improve contractility in sepsis by enhancing myofilament calcium sensitivity. We examined whether the calcium sensitizer levosimendan mitigates myocardial dysfuncti...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-003-1879-8

    authors： Behrends M,Peters J

    更新日期：2003-10-01 00:00:00

  • The management of arrhythmias following an acute myocardial infarction.

    abstract：:Arrhythmias are extremely common early after AMI. An arrhythmia is defined by exclusion, either because the sequence of myocardial depolarisation is other than normal or because certain arbitrary limits are exceeded. It follows that the term "arrhythmia" encompasses a complex heterogenous group. Although arrhythmias a...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01683131

    authors： Rowlands DJ

    更新日期：1978-01-01 00:00:00

  • End-of-life decisions in intensive care units: attitudes of physicians in an Italian urban setting.

    abstract：OBJECTIVE:To assess the attitudes of physicians in Milan, Italy, intensive care units (ICUs) regarding end-of-life decisions. DESIGN:Anonymous self-administered questionnaire. SETTING:All 20 ICUs in Milan. PARTICIPANTS:Physicians employed in the ICUs. MEASUREMENTS AND RESULTS:The response rate was 87% (225 of 259)....

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-003-1919-4

    authors： Giannini A,Pessina A,Tacchi EM

    更新日期：2003-11-01 00:00:00

  • Emergency endovascular treatment of a life-threatening hemorrhage from traumatic rupture of the left extracranial vertebral artery.

    abstract：:Hemorrhagic complications from transection of cervical arteries in blunt traumas are rare. We report a case of potentially fatal hemorrhage from rupture of the left vertebral artery in a closed trauma, successfully treated by endovascular injection of glue. Endovascular embolization may be considered as an alternative...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340051033

    authors： Simionato F,Righi C,Silvani P,Torri G,Scotti G

    更新日期：1999-10-01 00:00:00

  • Albumin bolus administration versus continuous infusion in critically ill hypoalbuminemic pediatric patients.

    abstract：OBJECTIVE:To test the hypothesis that the rate of degradation of exogenously administered albumin is faster with bolus administration than with continuous infusion and thus that a bolus administration is less efficacious in restoring blood albumin concentration (BAC) in the hypoalbuminemic critically ill pediatric pati...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章

    doi：10.1007/BF01712175

    authors： Greissman A,Silver P,Nimkoff L,Sagy M

    更新日期：1996-05-01 00:00:00

  • Nosocomial sinusitis with isolation of anaerobic bacteria in ICU patients.

    abstract：OBJECTIVE:To determine the frequency and the eventual clinical characteristics of nosocomial sinusitis with anaerobic bacteria isolation in patients in the intensive care unit (ICU). DESIGN:Retrospective study. SETTING:A 12-bed medical ICU in a teaching hospital. PATIENTS:30 adult patients with documented nosocomial...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340051013

    authors： Le Moal G,Lemerre D,Grollier G,Desmont C,Klossek JM,Robert R

    更新日期：1999-10-01 00:00:00

  • Could resuscitation be based on microcirculation data? We are not sure.

    abstract：: ...

    journal_title：Intensive care medicine

    pub_type： 信件

    doi：10.1007/s00134-018-5180-2

    authors： Monnet X,Saugel B

    更新日期：2018-06-01 00:00:00

  • Candesartan improves survival following severe hypovolemia in pigs; a role for the angiotensin II type 2 receptor?

    abstract：OBJECTIVE:To investigate the involvement of intestinal angiotensin II type 2 receptors in the outcome of acute severe hypovolemia as well as systemic and regional mesenteric hemodynamics and intestinal mucosal functions in anesthetized pigs. DESIGN AND SETTING:Prospective, interventional animal study in a university r...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s00134-005-2686-1

    authors： Laesser M,Spak E,Ewert S,Aneman A,Fandriks L

    更新日期：2005-08-01 00:00:00

  • Electron-microscopic description of accretions occurring on tips of infected and non-infected central venous catheters.

    abstract：OBJECTIVE:The purpose of the study was do describe the architecture of accretions occurring on the tips of central venous catheters (CVC). DESIGN:A conservative procedure was used followed by two different techniques of electron microscopy. SETTING AND PATIENTS:the study included 19 catheters which have been used on ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/BF01708582

    authors： Poisson DM,Touquet S,Bercault N,Arbeille B

    更新日期：1992-01-01 00:00:00

  • Plasma and lung concentrations of ceftazidime administered in continuous infusion to critically ill patients with severe nosocomial pneumonia.

    abstract：OBJECTIVE:To determine the steady-state plasma and epithelial lining fluid (ELF) concentrations of ceftazidime administered in continuous infusion to critically ill patients with severe nosocomial pneumonia. DESIGN:Prospective, open-label study. SETTING:An intensive care unit and research ward in a university hospita...

    journal_title：Intensive care medicine

    pub_type： 临床试验,杂志文章

    doi：10.1007/s00134-004-2171-2

    authors： Boselli E,Breilh D,Rimmelé T,Poupelin JC,Saux MC,Chassard D,Allaouchiche B

    更新日期：2004-05-01 00:00:00

  • Ultrasound-guided percutaneous dilatational tracheostomy: a safe method to avoid cranial misplacement of the tracheostomy tube.

    abstract：:The aim of this investigation was to evaluate the role of ultrasonography in avoiding cranial misplacement of the tracheostomy tube and tracheal ring fractures during percutaneous dilatational tracheostomy (PDT). The tracheas of 26 consecutive ICU patients who had undergone PDT but who later died were removed en bloc ...

    journal_title：Intensive care medicine

    pub_type： 杂志文章

    doi：10.1007/s001340000589

    authors： Sustić A,Kovac D,Zgaljardić Z,Zupan Z,Krstulović B

    更新日期：2000-09-01 00:00:00