Influence of parenteral fat administration on the pulmonary vascular system in man.

abstract：:Optimal fluid management is one of the main challenges in the care of the critically ill. However, the physiological parameters that are commonly monitored and used to guide fluid management are often inadequate and even misleading. From 1987 to 1989 we published four experimental studies which described a method for ...

journal_title：Intensive care medicine

authors： Perel A,Pizov R,Cotev S

更新日期：2014-06-01 00:00:00

abstract：:Physicians are increasingly involved in how their critically ill patients die [72]. The more this happens, the more physicians will have to understand not only how their own backgrounds and biases influence their medical management, but also the cultural and religious backgrounds of the patient and surrogate [72, 73]....

journal_title：Intensive care medicine

authors： Nyman DJ,Sprung CL

更新日期：2000-10-01 00:00:00

abstract：PURPOSE:Venous thromboembolism (VTE) is a common but often overlooked life-threatening complication of critical illness. The aim of this cross-sectional survey was to assess current practice of thromboprophylaxis as well as adherence to international guidelines. METHODS:After ethics committee approval, all intensive c...

journal_title：Intensive care medicine

authors： Schaden E,Metnitz PG,Pfanner G,Heil S,Pernerstorfer T,Perger P,Schoechl H,Fries D,Guetl M,Kozek-Langenecker S

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:To determine the incidence of and risk factors for adverse cardiac events during catecholamine vasopressor therapy in surgical intensive care unit patients with cardiovascular failure. METHODS:The occurrence of any of seven predefined adverse cardiac events (prolonged elevated heart rate, tachyarrhythmia, myoc...

journal_title：Intensive care medicine

authors： Schmittinger CA,Torgersen C,Luckner G,Schröder DC,Lorenz I,Dünser MW

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:Diagnosing persistent acute kidney injury (AKI) as opposed to transient AKI in critically ill patients may help physicians in making treatment decisions. This diagnosis relies chiefly on urinary indices, which may be of limited value or difficult to obtain. We assessed the performance of the Doppler renal re...

journal_title：Intensive care medicine

authors： Darmon M,Schortgen F,Vargas F,Liazydi A,Schlemmer B,Brun-Buisson C,Brochard L

更新日期：2011-01-01 00:00:00

abstract：:One hundred and eighteen 20-g radial artery catheters were prospectively evaluated in 109 cardiovascular surgical patients. 0.024% papaverine in saline was used as a continuous flushing solution. Using the Doppler method, obstruction of the radial artery with the catheter in situ was found in 11 (9.8%) patients. Decan...

journal_title：Intensive care medicine

authors： Weiss BM,Gattiker RI

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:Severe acute pancreatitis (SAP) remains a life-threatening disease with classic etiology of systemic inflammatory response and mortality between 30 and 50 %. The aim of the present study is to compare two different treatment strategies of goal-directed hemodynamic management and evaluate their impact on surviva...

journal_title：Intensive care medicine

authors： Trepte CJ,Bachmann KA,Stork JH,Friedheim TJ,Hinsch A,Goepfert MS,Mann O,Izbicki JR,Goetz AE,Reuter DA

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:A retrieval program was developed in New South Wales (NSW), Australia to provide extracorporeal membrane oxygenation support (ECMO) for the safe transport of adults with severe, acute respiratory or cardiac failure. We describe the development and results of this program and the impact of the 2009 H1N1 epidemic...

journal_title：Intensive care medicine

authors： Forrest P,Ratchford J,Burns B,Herkes R,Jackson A,Plunkett B,Torzillo P,Nair P,Granger E,Wilson M,Pye R

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To describe a real-time ultrasound sign, the visualization of the cavity and the walls of the maxillary sinus ("sinusogram"), and to assess its correlation with total opacity of the sinus. DESIGN:Prospective clinical study. SETTING:The medical ICU of a university-affiliated hospital. PATIENTS:The significa...

journal_title：Intensive care medicine

authors： Lichtenstein D,Biderman P,Mezière G,Gepner A

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:The Sonoclot analyser provides global measurement of haemostasis, including plasma coagulation, platelet function and fibrinolysis. Benefits of its use in cardiovascular and hepatic surgery are well-documented and it may be useful in managing obstetric complications. The aim of this study was to determine ran...

journal_title：Intensive care medicine

authors： Kjellberg U,Hellgren M

更新日期：2000-02-01 00:00:00

abstract：PURPOSE:Mechanical ventilation with lower tidal volumes (≤6 ml/kg of predicted body weight, PBW) could benefit patients without acute respiratory distress syndrome (ARDS). However, tidal volume reduction could be associated with increased patient discomfort and sedation needs, and consequent longer duration of ventilat...

journal_title：Intensive care medicine

authors： Serpa Neto A,Simonis FD,Barbas CS,Biehl M,Determann RM,Elmer J,Friedman G,Gajic O,Goldstein JN,Horn J,Juffermans NP,Linko R,de Oliveira RP,Sundar S,Talmor D,Wolthuis EK,de Abreu MG,Pelosi P,Schultz MJ

更新日期：2014-07-01 00:00:00

abstract：:The effects of continuous and supplementary bolus dose administration of etomidate have been investigated in ten artificially ventilated patients in traumatic coma. Continuous infusion of etomidate (5-25 micrograms/kg/min) proved to be a practical and safe means of sedating these patients and appeared to control moder...

journal_title：Intensive care medicine

authors： Prior JG,Hinds CJ,Williams J,Prior PF

更新日期：1983-01-01 00:00:00

abstract：OBJECTIVE:To examine the attitudes of the general public regarding who should decide about the withdrawal of life support and to compare these attitudes with those of intensive care personnel. DESIGN:Nationwide postal questionnaire survey. SETTING:Sweden. PARTICIPANTS:One thousand one hundred ninety-six randomly sel...

journal_title：Intensive care medicine

authors： Sjökvist P,Nilstun T,Svantesson M,Berggren L

更新日期：1999-09-01 00:00:00

abstract：:In hypoxia sensitive cells and tissues, the rates of glucose and O2 consumption are inversely related (Pasteur Effect). Under O2 limiting conditions the demands for glucose (glycogen) in such cells may drastically rise as a means for maintaining ATP turnover close to normoxic rates; nevertheless ion and electrical pot...

journal_title：Intensive care medicine

authors： Hochachka PW

更新日期：1986-01-01 00:00:00

abstract：INTRODUCTION:Extracorporeal carbon dioxide removal (ECCO2R) has been proposed for hypercapnic respiratory failure in chronic obstructive pulmonary disease (COPD) exacerbations, to avoid intubation or reduce length of invasive ventilation. Balance of risks, efficacy, and benefits of ECCO2R in patients with COPD is uncle...

journal_title：Intensive care medicine

authors： Sklar MC,Beloncle F,Katsios CM,Brochard L,Friedrich JO

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:In normal subjects cerebral CO2 vasoreactivity is measured during spontaneous hyperventilation, breathholding, or adding CO2 to inspiratory gases. The correlation between CO2 and cerebral blood flow may, however, be invalidated by the effects of a modified respiratory pattern on venous return, sympathovagal b...

journal_title：Intensive care medicine

authors： Cigada M,Marzorati S,Tredici S,Iapichino G

更新日期：2000-06-01 00:00:00

abstract：:As a result of the previous shortage of tools to assess objectively the overall physiological status of the respiratory system in infants and young children, it has been difficult to measure the degree of physiological disorder or the response to therapy in respiratory diseases such as BPD, the pediatric version of AR...

journal_title：Intensive care medicine

authors： Hammer J,Newth CJ

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:The evaluation of incidences and relating factors of severe persisting critical illness polyneuropathy (CIP) in survivors of multiple organ failure (MOF). DESIGN:Prospective study with an entry period of 24 months. Electrophysiological studies for the diagnosis of CIP were performed 1 or 2 days before the pa...

journal_title：Intensive care medicine

authors： Mohr M,Englisch L,Roth A,Burchardi H,Zielmann S

更新日期：1997-11-01 00:00:00

abstract：PURPOSE:To systematically review clinical and preclinical data on hydroxyethyl starch (HES) tissue storage. METHODS:MEDLINE (PubMed) was searched and abstracts were screened using defined criteria to identify articles containing original data on HES tissue accumulation. RESULTS:Forty-eight studies were included: 37 h...

journal_title：Intensive care medicine

authors： Wiedermann CJ,Joannidis M

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Vasopressors are administered to critically ill patients with vasodilatory shock not responsive to volume resuscitation, and less often in cardiogenic shock, and hypovolemic shock. OBJECTIVES:The objectives are to review safety and efficacy of vasopressors, pathophysiology, agents that decrease vasopressor ...

journal_title：Intensive care medicine

authors： Russell JA

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:We assessed the methodological trial quality of individual randomized controlled studies on chlorhexidine silver sulfadiazine impregnated catheters and the effect on catheter-related infection (CRI). DESIGN:Only the studies identified in the Medline database from 1966 to December 2001 were considered, abstra...

journal_title：Intensive care medicine

authors： Geffers C,Zuschneid I,Eckmanns T,Rüden H,Gastmeier P

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:Both serum levels of tumor necrosis factor-alpha (TNF alpha) and interleukin-6 (IL-6) and blood lactate levels in patients with septic shock have been shown to correlate with prognosis. The aim of the study was to define the relative predictive value of these measures. PATIENTS:38 hospitalized patients with ...

journal_title：Intensive care medicine

authors： Marecaux G,Pinsky MR,Dupont E,Kahn RJ,Vincent JL

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:Nuclear factor-kappaB (NF-kappaB) is a transcription factor which plays a pivotal role in the induction of genes involved in the response to injury and inflammation. Calpain I inhibitor is a potent antioxidant which is an effective inhibitor of NF-kappaB. This study examined whether the postulate that calpain...

journal_title：Intensive care medicine

authors： Virlos I,Mazzon E,Serraino I,Genovese T,Di Paola R,Thiemerman C,Siriwardena A,Cuzzocrea S

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:A closed suction system (CS) maintains connection with the mechanical ventilator during tracheal suctioning and is claimed to limit loss in lung volume and oxygenation. We compared changes in lung volume, oxygenation, airway pressure and hemodynamics during endotracheal suctioning performed with CS and with a...

journal_title：Intensive care medicine

authors： Cereda M,Villa F,Colombo E,Greco G,Nacoti M,Pesenti A

更新日期：2001-04-01 00:00:00

abstract：:Plasma colloid osmotic pressure (COP) has been calculated from both serum albumin concentration and plasma total protein concentration. These values have been compared to those measured directly using a membrane-transducer oncometer in a group of normal subjects, in a group of critically-ill patients with a variety of...

journal_title：Intensive care medicine

authors： Barclay SA,Bennett D

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:The use of heat and moisture exchangers (HME) during noninvasive ventilation (NIV) can increase the work of breathing, decrease alveolar ventilation, and deliver less humidity in comparison with heated humidifiers (HH). We tested the hypothesis that the use of HH during NIV with ICU ventilators for patients wit...

journal_title：Intensive care medicine

authors： Lellouche F,L'Her E,Abroug F,Deye N,Rodriguez PO,Rabbat A,Jaber S,Fartoukh M,Conti G,Cracco C,Richard JC,Ricard JD,Mal H,Mentec H,Loisel F,Lacherade JC,Taillé S,Brochard L

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:The aim of this prospective study was to evaluate the value of sinus echography results to directly indicate a transnasal puncture in intubated patients with suspicion of nosocomial maxillary sinusitis. DESIGN:prospective clinical investigation. SETTING:medical intensive care unit. PATIENTS:sixty patients ...

journal_title：Intensive care medicine

authors： Vargas F,Bui HN,Boyer A,Bébear CM,Lacher-Fougére S,De-Barbeyrac BM,Salmi LR,Traissac L,Gbikpi-Benissan G,Gruson D,Hilbert G

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To compare outcome prediction using the Multiple Organ Dysfunction Score (MODS) and the Sequential Organ Failure Assessment (SOFA), two of the systems most commonly used to evaluate organ dysfunction in the intensive care unit (ICU). DESIGN:Prospective, observational study. SETTING:Thirty-one-bed, universit...

journal_title：Intensive care medicine

authors： Peres Bota D,Melot C,Lopes Ferreira F,Nguyen Ba V,Vincent JL

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:The efficacy of interferon gamma therapy in reducing infection and improving outcome from infection in patients sustaining major injury was examined. DESIGN:Randomized double-blind placebo control trial SETTING:Nine level one university affiliated trauma centers in the United States. PATIENTS AND PARTICIPA...

journal_title：Intensive care medicine

authors： Dries DJ

更新日期：1996-10-01 00:00:00

abstract：:The pharmacokinetics of theophylline and ethylenediamine were examined in 6 patients with septicaemia and multiorgan failure (MOF). The patients received a bolus injection of 4 mg/kg aminophylline. Aminophylline is the ethylenediamine salt of theophylline. The clearance of theophylline was reduced in all our patients ...

journal_title：Intensive care medicine

authors： Toft P,Heslet L,Hansen M,Klitgaard NA

更新日期：1991-01-01 00:00:00