Disseminated zygomycosis and systemic lupus erythematosus.

Abstract:

:A young woman with long-standing systemic lupus erythematosus and rheumatic fever presented with deteriorating renal function. She had severe gastritis treated with cimetidine and received methylprednisolone when her blood cultures were repeatedly negative. She developed spontaneous bruising and bleeding from venepuncture sites, leading to clotting studies and a diagnosis of thrombotic thrombocytopenic purpura. At post-mortem, extensive evidence of disseminated zygomycosis was found. The likely portal of entry was the gastric route.

journal_name

Intensive Care Med

journal_title

Intensive care medicine

authors

Bloxham CA,Carr S,Ryan DW,Kesteven PJ,Bexton RS,Griffiths ID,Richards J

doi

10.1007/BF01724803

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

201-7

issue

3

eissn

0342-4642

issn

1432-1238

journal_volume

16

pub_type

杂志文章
  • Evaluation of severity scoring systems in ICUs--translation, conversion and definition ambiguities as a source of inter-observer variability in Apache II, SAPS and OSF.

    abstract:OBJECTIVE:To explore translation, conversion and definition ambiguities, when using severity scoring systems in patients admitted to intensive care units (ICUs). DESIGN:A prospective study of the prognosis of acute renal failure in ICUs. SETTING:The study was conducted in 20 French ICUs. PATIENTS:360 patients presen...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF01705416

    authors: Féry-Lemonnier E,Landais P,Loirat P,Kleinknecht D,Brivet F

    更新日期:1995-04-01 00:00:00

  • Fibrinolytic changes in a patient with toxic shock syndrome; release of active u-PA.

    abstract:OBJECTIVE:Definition of the changes in the activators of plasminogen, u-PA and t-PA, and examination of the possible generation of plasmin in the circulation in overwhelming sepsis. DESIGN:Serial blood analysis starting 4 h after development of symptoms of toxic shock syndrome. SETTING:Intensive care unit. PATIENT:A...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340050561

    authors: Haj MA,Robbie LA,Croll A,Adey GD,Bennett B

    更新日期:1998-03-01 00:00:00

  • Systemic antibiotic treatment of nosocomial pneumonia.

    abstract::Nosocomial pneumonia continues to represent a significant cause of morbidity and mortality in hospitalized patients. Bacteria are responsible for greater than 90% of the pneumonias, the most common isolates being aerobic Gram-negative bacilli and S. aureus. Cornerstones of treatment are intravenous antibiotics and sup...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/BF01752974

    authors: Unertl KE,Lenhart FP,Forst H,Peter K

    更新日期:1992-01-01 00:00:00

  • Changes of right ventricular function with positive end-expiratory pressure (PEEP) in man.

    abstract::The side effects of positive pressure ventilation on cardiovascular function are well known. However, in most clinical studies its influence on left ventricular function was examined. In the present study right ventricular (RV) performance was studied in 13 patients undergoing coronary artery bypass grafting during me...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF00256962

    authors: Neidhart PP,Suter PM

    更新日期:1988-01-01 00:00:00

  • Elevation of creatine kinase is associated with worse outcomes in 2009 pH1N1 influenza A infection.

    abstract:BACKGROUND:Current medical knowledge lacks specific information regarding creatine kinase (CK) elevation in influenza A pH1N1 (2009) infection. OBJECTIVES:Primary endpoints were correlation between CK at intensive care unit (ICU) admission and ICU mortality. Secondary endpoints were ICU length of stay (LOS), mechanica...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-012-2565-5

    authors: Borgatta B,Pérez M,Rello J,Vidaur L,Lorente L,Socías L,Pozo JC,Pozo J,Garnacho-Montero J,Rello J,pH1N1 GTEI\/SEMICYUC.

    更新日期:2012-07-01 00:00:00

  • Metabolomics in pneumonia and sepsis: an analysis of the GenIMS cohort study.

    abstract:PURPOSE:To determine the global metabolomic profile as measured in circulating plasma from surviving and non-surviving patients with community-acquired pneumonia (CAP) and sepsis. METHODS:Random, outcome-stratified case-control sample from a prospective study of 1,895 patients hospitalized with CAP and sepsis. Cases (...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00134-013-2935-7

    authors: Seymour CW,Yende S,Scott MJ,Pribis J,Mohney RP,Bell LN,Chen YF,Zuckerbraun BS,Bigbee WL,Yealy DM,Weissfeld L,Kellum JA,Angus DC

    更新日期:2013-08-01 00:00:00

  • Room air dilution of heliox given by facemask.

    abstract:OBJECTIVES:To measure the extent of dilution of helium-oxygen (heliox) by room air when given via high concentration reservoir mask to spontaneously breathing subjects. Substantial dilution of heliox by room air under these circumstances might alter its physical properties sufficiently to negate any potential clinical ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00134-008-1064-1

    authors: Standley TD,Smith HL,Brennan LJ,Wilkins IA,Bradley PG,Barrera Groba C,Davey AJ,Menon DK,Wheeler DW

    更新日期:2008-08-01 00:00:00

  • Measurement of functional residual capacity by helium dilution during partial support ventilation: in vitro accuracy and in vivo precision of the method.

    abstract:OBJECTIVE:Measurement of functional residual capacity (FRC) during controlled and especially during assisted ventilation remains a challenge in the physiological evaluation of ventilated patients. To validate a bag-in-box closed helium dilution technique allowing measurements both during pressure-controlled (PCV) and p...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-007-0833-6

    authors: Di Marco F,Rota Sperti L,Milan B,Stucchi R,Centanni S,Brochard L,Fumagalli R

    更新日期:2007-12-01 00:00:00

  • A prospective study of factors influencing the outcome of patients after a Medical Emergency Team review.

    abstract:OBJECTIVE:To identify factors that predict outcome in patients receiving a Medical Emergency Team review. DESIGN:Prospective observational study. SETTING:Tertiary hospital. PATIENTS:Cohort of 228 patients receiving one or more Medical Emergency Team reviews during daytime hours over a 1-year-period. Control cohort o...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-008-1229-y

    authors: Calzavacca P,Licari E,Tee A,Egi M,Haase M,Haase-Fielitz A,Bellomo R

    更新日期:2008-11-01 00:00:00

  • Delirium assessment in the critically ill.

    abstract:OBJECTIVE:To compare available instruments for assessing delirium in critically ill adults that have undergone validity testing and provide clinicians with strategies to incorporate these instruments into clinical practice. DESIGN:Medline (1966-September 2006) was searched using the key words: delirium, cognitive dysf...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-007-0603-5

    authors: Devlin JW,Fong JJ,Fraser GL,Riker RR

    更新日期:2007-06-01 00:00:00

  • The combination of the load/force balance and the frequency/tidal volume can predict weaning outcome.

    abstract:OBJECTIVE:To examine whether an appropriately designed combination of an index of ventilatory endurance and the frequency divided by tidal volume ratio (f/VT) provides prognostic information for weaning outcome not offered by any index alone. DESIGN AND SETTING:Prospective study in a multidisciplinary intensive care u...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-006-0104-y

    authors: Vassilakopoulos T,Routsi C,Sotiropoulou C,Bitsakou C,Stanopoulos I,Roussos C,Zakynthinos S

    更新日期:2006-05-01 00:00:00

  • Emergency correction of coagulation for mitral valve replacement in an orally anticoagulated 17-year-old patient with pronounced hepatic dysfunction.

    abstract::A 17-year-old patient with Shone's disease had to be readmitted to the hospital 3 months after implantation of an artificial aortic valve because of extreme mitral insufficiency with consecutive pulmonary edema and hepatic dysfunction. He had been orally anticoagulated and presented with a high international normalize...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340051023

    authors: Rauch R,Hofbeck M,Ries M,Singer H,Klinge J

    更新日期:1999-10-01 00:00:00

  • The calcium sensitizer levosimendan attenuates endotoxin-evoked myocardial dysfunction in isolated guinea pig hearts.

    abstract:OBJECTIVE:Sepsis-evoked myocardial dysfunction is possibly due to decreased myofilament calcium sensitivity, and a calcium sensitizer may thus specifically improve contractility in sepsis by enhancing myofilament calcium sensitivity. We examined whether the calcium sensitizer levosimendan mitigates myocardial dysfuncti...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-003-1879-8

    authors: Behrends M,Peters J

    更新日期:2003-10-01 00:00:00

  • Adaptive support ventilation versus conventional ventilation for total ventilatory support in acute respiratory failure.

    abstract:OBJECTIVE:To compare the short-term effects of adaptive support ventilation (ASV), an advanced closed-loop mode, with conventional volume or pressure-control ventilation in patients passively ventilated for acute respiratory failure. DESIGN:Prospective crossover interventional multicenter trial. SETTING:Six European ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00134-010-1917-2

    authors: Iotti GA,Polito A,Belliato M,Pasero D,Beduneau G,Wysocki M,Brunner JX,Braschi A,Brochard L,Mancebo J,Ranieri VM,Richard JC,Slutsky AS

    更新日期:2010-08-01 00:00:00

  • The association between hyperoxia and patient outcomes after cardiac arrest: analysis of a high-resolution database.

    abstract:PURPOSE:Previous observational studies have inconsistently associated early hyperoxia with worse outcomes after cardiac arrest, and have methodological limitations. We tested this association using a high-resolution database controlling for multiple disease-specific markers of severity of illness and care processes. M...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-014-3555-6

    authors: Elmer J,Scutella M,Pullalarevu R,Wang B,Vaghasia N,Trzeciak S,Rosario-Rivera BL,Guyette FX,Rittenberger JC,Dezfulian C,Pittsburgh Post-Cardiac Arrest Service (PCAS).

    更新日期:2015-01-01 00:00:00

  • Diagnostic yield and safety of CT scans in ICU.

    abstract:PURPOSE:Critically ill patients often require CT scans. Adverse events (AE) can occur during intra-hospital transport (IHT). The aim of this prospective study was to determine the diagnostic and therapeutic yield and the safety of CT scans in ICU patients. METHODS:All ICU patients having a CT scan for diagnostic purpo...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00134-014-3592-1

    authors: Aliaga M,Forel JM,De Bourmont S,Jung B,Thomas G,Mahul M,Bisbal M,Nougaret S,Hraiech S,Roch A,Chaumoitre K,Jaber S,Gainnier M,Papazian L

    更新日期:2015-03-01 00:00:00

  • Cerebral CO2 vasoreactivity evaluation by transcranial Doppler ultrasound technique: a standardized methodology.

    abstract:OBJECTIVE:In normal subjects cerebral CO2 vasoreactivity is measured during spontaneous hyperventilation, breathholding, or adding CO2 to inspiratory gases. The correlation between CO2 and cerebral blood flow may, however, be invalidated by the effects of a modified respiratory pattern on venous return, sympathovagal b...

    journal_title:Intensive care medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/s001340051239

    authors: Cigada M,Marzorati S,Tredici S,Iapichino G

    更新日期:2000-06-01 00:00:00

  • Procalcitonin for early diagnosis and differentiation of SIRS, sepsis, severe sepsis, and septic shock.

    abstract:OBJECTIVE:To determine the value of procalcitonin (PCT) in the early diagnosis (and differentiation) of patients with SIRS, sepsis, severe sepsis, and septic shock in comparison to C-reactive protein (CRP), white blood cell and thrombocyte count, and APACHE-II score (AP-II). DESIGN:Prospective cohort study including a...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF02900728

    authors: Brunkhorst FM,Wegscheider K,Forycki ZF,Brunkhorst R

    更新日期:2000-03-01 00:00:00

  • Clonidine as a sedative adjunct in intensive care.

    abstract::A 63-year-old man underwent distal oesophagectomy and proximal gastrectomy. Postoperatively, controlled ventilation was necessary for 53 days because of anastomotic leakage. Multiple sedative regimens proved to be inadequate. By contrast, a fentanyl-midazolam combination with continuous supplementation of clonidine 0....

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF01705163

    authors: Böhrer H,Bach A,Layer M,Werning P

    更新日期:1990-01-01 00:00:00

  • Continuous flush devices for vascular pressure monitoring.

    abstract::Six different types of continuous flush devices have been assessed for accuracy in vitro and ease of use in vivo. Only two types of device matched the manufacturers' specifications of performance. The other four gave higher flow rates than expected. ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF01691259

    authors: Rithalia SV,Tinker J

    更新日期:1983-01-01 00:00:00

  • Immediate prediction of recovery of consciousness after cardiac arrest.

    abstract:OBJECTIVE:Short-latency somatosensory evoked potential (SSEP) monitoring has been reported to be useful in predicting neurological outcome in patients with cardiac arrest and hypoxic-ischemic encephalopathy. To obtain the immediate data of SSEP and evaluate the relationship between the presence of cortical activity and...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340100984

    authors: Nakabayashi M,Kurokawa A,Yamamoto Y

    更新日期:2001-07-01 00:00:00

  • Colonization and infection in surgical intensive care patients--a prospective study.

    abstract::Nosocomial infections are a major problem in intensive care patients. Thirty-nine patients, requiring intensive care for 5 days or more (mean 15.8 days) were prospectively investigated, to determine the relation between colonisation and nosocomial infection. Thrice weekly, cultures from the oropharynx, respiratory and...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF00255792

    authors: Kerver AJ,Rommes JH,Mevissen-Verhage EA,Hulstaert PF,Vos A,Verhoef J,Wittebol P

    更新日期:1987-01-01 00:00:00

  • Impact of lung ultrasound on clinical decision making in critically ill patients.

    abstract:PURPOSE:To assess the impact of lung ultrasound (LU) on clinical decision making in mechanically ventilated critically ill patients. METHODS:One hundred and eighty-nine patients took part in this prospective study. The patients were enrolled in the study when LU was requested by the primary physician for (1) unexplain...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-013-3133-3

    authors: Xirouchaki N,Kondili E,Prinianakis G,Malliotakis P,Georgopoulos D

    更新日期:2014-01-01 00:00:00

  • Transpulmonary gradient of type III procollagen peptides: acute effects of cardio-pulmonary bypass.

    abstract::Type III procollagen N-peptides (PIIINPs) are believed to be released in stoichiometric amounts as type III collagen molecules are secreted from cells. We hypothesized that if the human lung actively produces type III collagen a detectable transpulmonary gradient in PIIINPs would exist in normal individuals that might...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/BF01706477

    authors: Harrison NK,Laurent GJ,Evans TW

    更新日期:1992-01-01 00:00:00

  • Tigecycline use in critically ill patients: a multicentre prospective observational study in the intensive care setting.

    abstract:PURPOSE:This prospective observational study aimed at describing prescription patterns of tigecycline and patient outcomes in 26 French intensive care units (ICU). METHODS:Data of consecutive cases of adult patients treated with tigecycline were collected from the initiation until 7 days after the end of treatment. Re...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00134-014-3323-7

    authors: Montravers P,Dupont H,Bedos JP,Bret P,Tigecycline Group.

    更新日期:2014-07-01 00:00:00

  • High-mobility group box 1 protein plasma concentrations during septic shock.

    abstract:OBJECTIVE:To investigate plasma high-mobility group box 1 protein (HMGB1) concentration and its relationship with organ dysfunction and outcome in septic shock patients. DESIGN AND SETTING:Prospective, noninterventional study. Medical adult intensive care unit at a university hospital in France. PATIENTS:42 criticall...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-007-0691-2

    authors: Gibot S,Massin F,Cravoisy A,Barraud D,Nace L,Levy B,Bollaert PE

    更新日期:2007-08-01 00:00:00

  • Correction to: Polymyxin B-immobilized hemoperfusion and mortality in critically ill adult patients with sepsis/septic shock: a systematic review with meta-analysis and trial sequential analysis.

    abstract::Owing to an oversight by the authors, Figure 2 in this article was not the version intended for publication. The correct Figure 2, reproduced here, features footnote symbols and Figure 2b includes three studies as described in the main text. ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s00134-018-5055-6

    authors: Fujii T,Ganeko R,Kataoka Y,Furukawa TA,Featherstone R,Doi K,Vincent JL,Pasero D,Robert R,Ronco C,Bagshaw SM

    更新日期:2018-02-01 00:00:00

  • Interventions to reduce medication prescribing errors in a paediatric cardiac intensive care unit.

    abstract:OBJECTIVE:To identify and reduce medication-prescribing errors by introducing systematic physician education and post-cardiac surgery admission prescription forms. DESIGN:Errors were defined as: incomplete prescriptions; potential adverse drug events (ADEs), i.e. either intercepted or non-intercepted incorrect prescri...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s00134-008-1054-3

    authors: Burmester MK,Dionne R,Thiagarajan RR,Laussen PC

    更新日期:2008-06-01 00:00:00

  • Effects of haemoconcentration and haemodilution on acute hypoxia-induced pulmonary hypertension and changes in vascular compliance of isolated rabbit lungs.

    abstract:OBJECTIVE:Erythrocytes influence the magnitude of hypoxia-induced pulmonary artery pressure increase. It is, however, unknown to what extent haemoconcentration and haemodilution affect this response and whether intrapulmonary blood volume (and thus vessel dimensions) alters the magnitude of pressure increase. Furthermo...

    journal_title:Intensive care medicine

    pub_type: 杂志文章

    doi:10.1007/s001340051327

    authors: Loer SA,Peters J

    更新日期:2000-08-01 00:00:00

  • Experts' opinion on management of hemodynamics in ARDS patients: focus on the effects of mechanical ventilation.

    abstract:RATIONALE:Acute respiratory distress syndrome (ARDS) is frequently associated with hemodynamic instability which appears as the main factor associated with mortality. Shock is driven by pulmonary hypertension, deleterious effects of mechanical ventilation (MV) on right ventricular (RV) function, and associated-sepsis. ...

    journal_title:Intensive care medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s00134-016-4326-3

    authors: Vieillard-Baron A,Matthay M,Teboul JL,Bein T,Schultz M,Magder S,Marini JJ

    更新日期:2016-05-01 00:00:00