Changes of right ventricular function with positive end-expiratory pressure (PEEP) in man.

abstract：OBJECTIVE:To evaluate the efficacy of different lung recruitment maneuvers using electric impedance tomography. DESIGN AND SETTING:Experimental study in animal model of acute lung injury in an animal research laboratory. SUBJECTS:Fourteen pigs with saline lavage induced lung injury. INTERVENTIONS:Lung volume, region...

journal_title：Intensive care medicine

authors： Odenstedt H,Lindgren S,Olegård C,Erlandsson K,Lethvall S,Aneman A,Stenqvist O,Lundin S

更新日期：2005-12-01 00:00:00

abstract：:A prospective study of thiamine status in patients with severe injuries (injury severity scores greater than 12) showed that they all developed signs of severe thiamine deficiency on the basis of transketolase activity, the standard biochemical test for thiamine deficiency. This occurred within the first week after th...

journal_title：Intensive care medicine

authors： McConachie I,Haskew A

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVE:To study the wishes of a sample of French patients about medical information and surrogacy, at a time when the French Ministry of Health is supporting increased patient autonomy. DESIGN:A cohort of competent patients with non-critical illnesses or injuries completed an intention-to-act questionnaire on the a...

journal_title：Intensive care medicine

authors： Roupie E,Santin A,Boulme R,Wartel JS,Lepage E,Lemaire F,Lejonc JL,Montagne O

更新日期：2000-01-01 00:00:00

abstract：:The process of fluidisation involves blowing warm air through small solid microspheres thus creating a liquid, without wetness. The warmth provides some important properties including reducing the metabolic rate in thermal injury which has a beneficial effect on mortality, modifying catabolism after surgery, providing...

journal_title：Intensive care medicine

authors： Ryan DW

更新日期：1995-03-01 00:00:00

abstract：PURPOSE:Intensive care unit survivors suffer from prolonged impairment, reduced quality of life, and higher mortality rates after discharge compared to the general population. Socioeconomic status may play a partial but important role in mortality and recovery. Therefore, the detection of factors that are responsible f...

journal_title：Intensive care medicine

authors： Bastian K,Hollinger A,Mebazaa A,Azoulay E,Féliot E,Chevreul K,Fournier MC,Guidet B,Michel M,Montravers P,Pili-Floury S,Sonneville R,Siegemund M,Gayat E,FROG-ICU Study Investigators.

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To compare isoflurane with midazolam for prolonged sedation in ventilated patients. DESIGN:Randomised controlled study. SETTING:General intensive care unit in university teaching hospital. PATIENTS:Sixty patients aged 17-80 years who required mechanical ventilation for more than 24 h. INTERVENTIONS:Sedati...

journal_title：Intensive care medicine

authors： Spencer EM,Willatts SM

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:To analyse the clinical value of procalcitonin (PCT), C-reactive protein (CRP) and leucocyte count in the diagnosis of paediatric sepsis and in the stratification of patients according to severity. DESIGN:Prospective, observational study. SETTING:Paediatric intensive care unit (PICU). PATIENTS:Ninety-four...

journal_title：Intensive care medicine

authors： Rey C,Los Arcos M,Concha A,Medina A,Prieto S,Martinez P,Prieto B

更新日期：2007-03-01 00:00:00

abstract：:We report a fatal case of a child presenting Reye's syndrome associated with a variety of arrhythmias and ischemia-like ST-T ECG changes. At autopsy, fatty infiltration and patchy myocytolysis were detected in sections of the heart. This case report emphasizes cardiac involvement in Reye's syndrome and the possible me...

journal_title：Intensive care medicine

authors： Sarti A,Cecchi F,Manetti A,Busoni P

更新日期：1996-01-01 00:00:00

abstract：:A study was conducted to evaluate repeated intrathecal injections of baclofen, without artificial ventilation, in the treatment of severe tetanus. Ten patients, 5 men and 5 women, with a mean age of 34 +/- 7 years, were included in the study. The dose of baclofen injected was 1000 micrograms between the ages of 16 and...

journal_title：Intensive care medicine

authors： Saissy JM,Demazière J,Vitris M,Seck M,Marcoux L,Gaye M,Ndiaye M

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To investigate the regional partial pressure of oxygen (PO2) and partial pressure of carbon dioxide (PCO2) of the perfluorocarbon liquid (PpfcO2, PpfcCO2) during partial liquid ventilation (PLV). DESIGN:Prospective, controlled study. SETTING:A research laboratory at a university medical center. SUBJECTS:Th...

journal_title：Intensive care medicine

authors： Uchida T,Yokoyama K,Nakazawa K,Makita K

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To investigate plasma high-mobility group box 1 protein (HMGB1) concentration and its relationship with organ dysfunction and outcome in septic shock patients. DESIGN AND SETTING:Prospective, noninterventional study. Medical adult intensive care unit at a university hospital in France. PATIENTS:42 criticall...

journal_title：Intensive care medicine

authors： Gibot S,Massin F,Cravoisy A,Barraud D,Nace L,Levy B,Bollaert PE

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:Common opioids for analgesia and sedation of mechanically ventilated infants may tend to accumulate and cause prolonged sedation with an unpredictable extubation time. Remifentanil is a promising option due to its unique pharmacokinetic properties, which seem to be valid in adults as well as in infants. METHOD...

journal_title：Intensive care medicine

authors： Welzing L,Oberthuer A,Junghaenel S,Harnischmacher U,Stützer H,Roth B

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:The immediate overwhelming release of inflammatory mediators in septic shock is rapidly followed by strong anti-inflammatory responses inducing a state of immunosuppression. The patients who survive the initial hyper-inflammatory step of septic shock but subsequently die may be those who do not recover from i...

journal_title：Intensive care medicine

authors： Monneret G,Lepape A,Voirin N,Bohé J,Venet F,Debard AL,Thizy H,Bienvenu J,Gueyffier F,Vanhems P

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:A readily available assessment of changes in pleural pressure would be useful for ventilator and fluid management in critically ill patients. We examined whether changes in pulmonary artery occlusion pressure (Ppao) adequately reflect respiratory changes in pleural pressure as assessed by changes in intraesop...

journal_title：Intensive care medicine

authors： Bellemare P,Goldberg P,Magder SA

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of prone positioning on systemic hemodynamics, intra-abdominal pressure (IAP), plasma disappearance rate of indocyanine green (PDR(ICG)), and gastric intramucosal to arterial PCO2 difference (Pi-aCO2). DESIGN AND SETTING:Prospective randomized study in the intensive care unit of a ...

journal_title：Intensive care medicine

authors： Hering R,Vorwerk R,Wrigge H,Zinserling J,Schröder S,von Spiegel T,Hoeft A,Putensen C

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:Motivated by a new randomized trial (the PEPTIC trial) that raised the issue of an increase in mortality with proton pump inhibitors (PPIs) relative to histamine-2 receptor antagonists (H2RAs), we updated our prior systematic review and network meta-analysis (NMA) addressing the impact of pharmacological gastro...

journal_title：Intensive care medicine

authors： Wang Y,Ge L,Ye Z,Siemieniuk RA,Reintam Blaser A,Wang X,Perner A,Møller MH,Alhazzani W,Cook D,Guyatt GH

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the influence of changes in alveolar ventilation on the following tonometry-derived variables: gastric intramucosal CO2 tension (PtCO2), gastric arterial CO2 tension difference (PgapCO2), gastric intramucosal pH (pHi) and arterial pH-pHi difference (pHgap). DESIGN:Clinical prospective study. SET...

journal_title：Intensive care medicine

authors： Bernardin G,Lucas P,Hyvernat H,Deloffre P,Mattéi M

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Ornithine alpha-ketoglutarate (OKG) has proved to be efficient in restoring glutamine (Gln) pools which are strongly depleted in hypercatabolic patients. Since its two components, alpha-ketoglutarate (alphaKG) and ornithine (Orn), give rise to glutamate (Glu), they are both considered as Gln precursors. The ...

journal_title：Intensive care medicine

authors： Cynober L,Lasnier E,Le Boucher J,Jardel A,Coudray-Lucas C

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:Assessing pulse pressure variation (PPV) to predict fluid responsiveness in mechanically ventilated patients with tidal volume (VT) and the impact of VT and airway driving pressure (P(plat) - PEEP) on the ability of PPV for predicting fluid responsiveness. DESIGN:Prospective interventional study. SETTING:IC...

journal_title：Intensive care medicine

authors： Muller L,Louart G,Bousquet PJ,Candela D,Zoric L,de La Coussaye JE,Jaber S,Lefrant JY

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between the base deficit value in the immediate postoperative period of coronary surgery for cardiopulmonary bypass and the length of stay in the ICU. DESIGN AND SETTING:Prospective descriptive study in the department of anesthesia and cardiovascular surgery of a university hospita...

journal_title：Intensive care medicine

authors： Hugot P,Sicsic JC,Schaffuser A,Sellin M,Corbineau H,Chaperon J,Ecoffey C

更新日期：2003-02-01 00:00:00

abstract：PURPOSE:Sepsis is a major health burden worldwide. Preclinical investigations in animals and retrospective studies in patients have suggested that inhibition of platelets may improve the outcome of sepsis. In this study we investigated whether chronic antiplatelet therapy impacts on the presentation and outcome of seps...

journal_title：Intensive care medicine

authors： Wiewel MA,de Stoppelaar SF,van Vught LA,Frencken JF,Hoogendijk AJ,Klein Klouwenberg PMC,Horn J,Bonten MJ,Zwinderman AH,Cremer OL,Schultz MJ,van der Poll T,MARS Consortium.

更新日期：2016-03-01 00:00:00

abstract：:A 29-year-old woman was admitted to the Rouen University Hospital for attempted suicide by ingestion of a carbamate insecticide (Temik G, containing 10% aldicarb). Cardio-respiratory arrest occurred at the second hour and acute necrotic hemorrhagic pancreatitis on the second day. Further evolution was uneventful, and ...

journal_title：Intensive care medicine

authors： Moritz F,Droy JM,Dutheil G,Melki J,Bonmarchand G,Leroy J

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To investigate efficacy and safety of enoxaparin for catheter-related arterial thrombosis in infants with congenital heart disease. DESIGN:Prospective observational study. SETTING:Pediatric Intensive Care and Cardiology Unit at the University Children's Hospital of Zurich. PATIENTS:A cohort of 32[Symbol: s...

journal_title：Intensive care medicine

authors： Bontadelli J,Moeller A,Schmugge M,Schraner T,Kretschmar O,Bauersfeld U,Bernet-Buettiker V,Albisetti M

更新日期：2007-11-01 00:00:00

abstract：:Production of beta-lactamases is the most important means of bacterial resistance to beta-lactam antibiotics. The traditional, plasmid-mediated beta-lactamases were initially confined to Enterobacteriaceae but have now spread to other genera and species including Pseudomonas aeruginosa, Haemophilus influenzae, and Nei...

journal_title：Intensive care medicine

authors： Garau J

更新日期：1994-07-01 00:00:00

abstract：PURPOSE:To determine incidence, risk factors and outcome of tracheal ischemic lesions related to intubation. METHODS:Planned post hoc analysis using patients from a previous randomized controlled study. Fiberoptic tracheoscopy was performed during the 24 h following extubation. In patients with >2 ischemic lesions, ul...

journal_title：Intensive care medicine

authors： Touat L,Fournier C,Ramon P,Salleron J,Durocher A,Nseir S

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To assess the utility of two in situ techniques, differential time to positivity (DTP) and semiquantitative superficial cultures (SQSC) for diagnosing catheter-related bloodstream infection (CR-BSI) in critically ill adults. METHODS:This was a prospective cohort study in patients with suspected CR-BSI arising ...

journal_title：Intensive care medicine

authors： Gowardman JR,Jeffries P,Lassig-Smith M,Stuart J,Jarrett P,Deans R,McGrail M,George NM,Nimmo GR,Rickard CM

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficiency of a new device developed to remove obstructions from endotracheal tubes (ETT) in mechanically ventilated patients. DESIGN:Open study in mechanically ventilated sedated and paralyzed ICU patients. SETTING:General ICU and Laboratory of Respiratory Mechanics of the University of Rom...

journal_title：Intensive care medicine

authors： Conti G,Rocco M,De Blasi RA,Lappa A,Antonelli M,Bufi M,Gasparetto A

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:To examine the benefits and risks of vasopressin or its analog terlipressin for patients with vasodilatory shock. DATA SOURCE:We searched the CENTRAL, MEDLINE, EMBASE, and LILACS databases (up to March 2011) as well as reference lists of articles and proceedings of major meetings; we also contacted trial aut...

journal_title：Intensive care medicine

authors： Polito A,Parisini E,Ricci Z,Picardo S,Annane D

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:Recalibration and determining discriminative power, internationally, of the existing delirium prediction model (PRE-DELIRIC) for intensive care patients. METHODS:A prospective multicenter cohort study was performed in eight intensive care units (ICUs) in six countries. The ten predictors (age, APACHE-II, urgen...

journal_title：Intensive care medicine

authors： van den Boogaard M,Schoonhoven L,Maseda E,Plowright C,Jones C,Luetz A,Sackey PV,Jorens PG,Aitken LM,van Haren FM,Donders R,van der Hoeven JG,Pickkers P

更新日期：2014-03-01 00:00:00

abstract：:Since the introduction of synchronized intermittent mandatory ventilation (SIMV) several advantages have been attributed to this ventilatory mode, one of them being a more homogeneous distribution of ventilation and perfusion than during controlled mechanical ventilation (CMV). Up to now no data are available to confi...

journal_title：Intensive care medicine

authors： Santak B,Radermacher P,Sandmann W,Falke KJ

更新日期：1991-01-01 00:00:00