Emergency correction of coagulation for mitral valve replacement in an orally anticoagulated 17-year-old patient with pronounced hepatic dysfunction.

abstract：:We report a case of fatal septic shock, with hyperlactatemia and blood cultures positive for Streptococcus pneumoniae, in a 70-year-old patient. On two occasions (5 days, and 2 days before the patient's death), the relationship between oxygen delivery (DO2) and consumption (VO2) was examined in conjunction with two pr...

journal_title：Intensive care medicine

authors： Gallet D,Goudable J,Vedrinne JM,Viale JP,Annat G

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:Fibroproliferation markers like procollagen I predict mortality in patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). We sought to determine whether bronchoalveolar lavage fluid (BALF) from patients with lung injury contained mediators that would activate procollagen I promo...

journal_title：Intensive care medicine

authors： Budinger GR,Chandel NS,Donnelly HK,Eisenbart J,Oberoi M,Jain M

更新日期：2005-01-01 00:00:00

abstract：PURPOSE:Polymyxin B-immobilized hemoperfusion (PMX-HP) is an adjuvant therapy for sepsis or septic shock that clears circulating endotoxin. Prior trials have shown that PMX-HP improves surrogate endpoints. We aimed to conduct an evidence synthesis to evaluate the efficacy and safety of PMX-HP in critically ill adult pa...

journal_title：Intensive care medicine

authors： Fujii T,Ganeko R,Kataoka Y,Furukawa TA,Featherstone R,Doi K,Vincent JL,Pasero D,Robert R,Ronco C,Bagshaw SM

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:Rapid shallow breathing may occur at any time during spontaneous breathing trials (SBT), questioning the utility of a single determination of the rapid shallow breathing index (RSBI). We hypothesize that change in RSBI during SBT may more accurately predict successful extubation than a single determination. ME...

journal_title：Intensive care medicine

authors： Segal LN,Oei E,Oppenheimer BW,Goldring RM,Bustami RT,Ruggiero S,Berger KI,Fiel SB

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:Hypoxia-ischemia (HI), as a major cause of fetal brain damage, has long-lasting neurological implications. Therefore, therapeutic interventions that attenuate the neuropathological outcome of HI while also improving the neurofunctional outcome are of paramount clinical importance. The aim of this study was to i...

journal_title：Intensive care medicine

authors： Fathali N,Lekic T,Zhang JH,Tang J

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Pseudomonas aeruginosa-induced lung injury is characterized not only by the alteration in lung fluid movement but also by apoptosis of lung epithelial and endothelial cells. We studied whether inhibition of apoptosis using a broad spectrum caspase inhibitor, benzyloxycarbonyl-Val-Ala-Asp fluoromethylketone (Z...

journal_title：Intensive care medicine

authors： Le Berre R,Faure K,Fauvel H,Viget NB,Ader F,Prangère T,Thomas AM,Leroy X,Pittet JF,Marchetti P,Guery BP

更新日期：2004-06-01 00:00:00

abstract：:Two patients with severe hepatic and renal failure underwent emergency hepatic retransplantation (2nd and 6th day after transplantation). Continuous arteriovenous haemodialysis was begun before surgery and successfully performed, without any incident, during the retransplantation with a biospal (SCU/CAVH AN 69 S) devi...

journal_title：Intensive care medicine

authors： Salord F,Bailly MP,Gaussorgues P,Workineh S,Pouyet M,Robert D

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:1) To compare saline gastric tonometry monitoring with air tonometry (Tonocap) in a group of general ICU patients. 2) An in vitro investigation of the performance of other fluids used in gastric tonometry and to assess the effects of variation of temperature and carbon dioxide concentration within the range e...

journal_title：Intensive care medicine

authors： Barry B,Mallick A,Hartley G,Bodenham A,Vucevic M

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:Oxygen consumption (VO2) obtained from respiratory gases by indirect calorimetry (VO2,IC) with a metabolic monitor integrated in a ventilator were to be compared to VO2 obtained by the Fick principle (VO2,Fick) in septic patients following an increase in oxygen delivery (DO2) induced by positive inotropic sup...

journal_title：Intensive care medicine

authors： Schaffartzik W,Sanft C,Schaefer JH,Spies C

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:The purpose of the study was do describe the architecture of accretions occurring on the tips of central venous catheters (CVC). DESIGN:A conservative procedure was used followed by two different techniques of electron microscopy. SETTING AND PATIENTS:the study included 19 catheters which have been used on ...

journal_title：Intensive care medicine

authors： Poisson DM,Touquet S,Bercault N,Arbeille B

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:The Guillain-Barré syndrome (GBS) is an acute inflammatory polyneuropathy related to autoimmunity. However, no conclusive etiological concept has yet been found. We examined the variation in autoantibodies to lipids in serum of GBS patients in response to the course of the disease but investigated titer modif...

journal_title：Intensive care medicine

authors： Nakos G,Tziakou E,Maneta-Peyret L,Nassis C,Lekka ME

更新日期：2005-10-01 00:00:00

abstract：PURPOSE:Meconium aspiration syndrome (MAS) is a life-threatening neonatal lung injury, whose pathophysiology has been mainly studied in animal models. In such models, pancreatic secretory phospholipase A2 (sPLA2-IB) and proinflammatory cytokines present in meconium challenge the lungs, catabolising surfactant and harmi...

journal_title：Intensive care medicine

authors： De Luca D,Minucci A,Tripodi D,Piastra M,Pietrini D,Zuppi C,Conti G,Carnielli VP,Capoluongo E

更新日期：2011-07-01 00:00:00

abstract：:Type III procollagen N-peptides (PIIINPs) are believed to be released in stoichiometric amounts as type III collagen molecules are secreted from cells. We hypothesized that if the human lung actively produces type III collagen a detectable transpulmonary gradient in PIIINPs would exist in normal individuals that might...

journal_title：Intensive care medicine

authors： Harrison NK,Laurent GJ,Evans TW

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:To measure plasma levels and pharmacokinetics of cefpirome in critically ill septic patients with normal renal function. To use the pharmacokinetic model to simulate alternate dosing regimens and identify those that predict sustained levels. DESIGN AND SETTING:A prospective, open-label, descriptive study in...

journal_title：Intensive care medicine

authors： Lipman J,Wallis SC,Rickard CM,Fraenkel D

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:The Pediatric Index of Mortality 2 (PIM2), one of the key mortality prediction models for children in intensive care units, has not been validated in Japan. The purpose of this study was to validate the performance of PIM2 in a population of patients admitted to one pediatric intensive care unit (PICU) in Jap...

journal_title：Intensive care medicine

authors： Imamura T,Nakagawa S,Goldman RD,Fujiwara T

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:We compared 1 versus 0.5 microg/kg bolus remifentanil versus placebo in alleviating pain due to chest drain removal. Effects on sedation, respiratory rate (RR), oxygen saturation, heart rate (HR) and blood pressure were also evaluated. METHODS:Sixty patients following cardiac surgery were enrolled in this pros...

journal_title：Intensive care medicine

authors： Casey E,Lane A,Kuriakose D,McGeary S,Hayes N,Phelan D,Buggy D

更新日期：2010-08-01 00:00:00

abstract：:Pneumonia caused by herpes simplex virus type 1 (HSV1) is rare and occurs in severely immunosuppressed patients. HSV1 can be detected in bronchoalveolar lavage (BAL) from patients presenting with respiratory failure, but its direct effect on disease is difficult to prove. We demonstrate the causative role of HSV1 in t...

journal_title：Intensive care medicine

authors： François-Dufresne A,Garbino J,Ricou B,Wunderli W

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVE:Comparison of side effects (fever shivering and/or allergic reactions, collapse, symptomatic hypocalcaemia) of the different substitution fluids used during therapeutical plasmapheresis. DESIGN:Multicentric retrospective comparative study designed to explore the side effects due to the replacements fluids (a...

journal_title：Intensive care medicine

authors： Korach JM,Berger P,Giraud C,Le Perff-Desman C,Chillet P

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the ability of DeltaPP/DeltaP [pulse pressure variations (DeltaPP) adjusted by alveolar pressure variations (DeltaP = Pplat-PEEPtot)] in predicting fluid responsiveness, to compare its accuracy to that of DeltaPP used alone and to evaluate the influence of tidal volume (Vt) on these two indices. ...

journal_title：Intensive care medicine

authors： Vallée F,Richard JC,Mari A,Gallas T,Arsac E,Verlaan PS,Chousterman B,Samii K,Genestal M,Fourcade O

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:To investigate the role of the inducible nitric oxide synthase activation-induced excess nitric oxide formation on the rate of hepatic glucose production during fully resuscitated murine septic shock. DESIGN:Prospective, controlled, randomized animal study. SETTING:University animal research laboratory. SU...

journal_title：Intensive care medicine

authors： Albuszies G,Vogt J,Wachter U,Thiemermann C,Leverve XM,Weber S,Georgieff M,Radermacher P,Barth E

更新日期：2007-06-01 00:00:00

abstract：:We present a patient with evidence of severe intravascular hemolysis after mitral valve repair, an established method for the surgical treatment of mitral valve disease to avoid prosthesis related complications. The coincidence of this uncommon complication with hemodynamic instability due to pre-existing myocardial d...

journal_title：Intensive care medicine

authors： Seyr M,Hasibeder W,Furtwaegler W,Antretter H,Mutz NJ

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To examine the usefulness of preload indices obtained by transoesophageal echocardiography (TOE) for estimating stroke volume at various levels of cardiac index. DESIGN:Prospective clinical study. SETTING:Intensive care unit with surgical patients. PATIENTS:16 ventilated patients monitored via Swan-Ganz ca...

journal_title：Intensive care medicine

authors： Greim CA,Roewer N,Apfel C,Laux G,Schulte am Esch J

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:To implement delirium monitoring, test reliability, and monitor compliance of performing the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) in trauma patients. DESIGN AND SETTING:Prospective, observational study in a level 1 trauma unit of a tertiary care, university-based medical center. ...

journal_title：Intensive care medicine

authors： Soja SL,Pandharipande PP,Fleming SB,Cotton BA,Miller LR,Weaver SG,Lee BT,Ely EW

更新日期：2008-07-01 00:00:00

abstract：:In severe status asthmaticus basic medical treatment often fails to improve the patient's condition. Mechanical ventilation in this situation is associated with a high incidence of serious complications. After the bronchodilating effect of moderate-dose magnesium sulfate in asthmatic patients had been demonstrated in ...

journal_title：Intensive care medicine

authors： Sydow M,Crozier TA,Zielmann S,Radke J,Burchardi H

更新日期：1993-01-01 00:00:00

abstract：:This narrative review focuses on thoracic ultrasonography (lung and pleural) with the aim of outlining its utility for the critical care clinician. The article summarizes the applications of thoracic ultrasonography for the evaluation and management of pneumothorax, pleural effusion, acute dyspnea, pulmonary edema, pu...

journal_title：Intensive care medicine

authors： Mayo PH,Copetti R,Feller-Kopman D,Mathis G,Maury E,Mongodi S,Mojoli F,Volpicelli G,Zanobetti M

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:Clinical examination is often the first step to diagnose shock and estimate cardiac index. In the Simple Intensive Care Studies-I, we assessed the association and diagnostic performance of clinical signs for estimation of cardiac index in critically ill patients. METHODS:In this prospective, single-centre coho...

journal_title：Intensive care medicine

authors： Hiemstra B,Koster G,Wiersema R,Hummel YM,van der Harst P,Snieder H,Eck RJ,Kaufmann T,Scheeren TWL,Perner A,Wetterslev J,de Smet AMGA,Keus F,van der Horst ICC,SICS Study Group.

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the origin of H+ ions participating in the generation of CO2 coming from sodium bicarbonate infusion during metabolic acidosis. We hypothesized that these H+ ions come from a back-titration of the main non-bicarbonate buffers present in the blood, i. e. the hemoglobin and the albumin, and thus pos...

journal_title：Intensive care medicine

authors： Levraut J,Garcia P,Giunti C,Ichai C,Bouregba M,Ciebiera JP,Payan P,Grimaud D

更新日期：2000-05-01 00:00:00

abstract：:The use of induced hypertension in head injury patients is controversial. We present the case of a 19-year-old man admitted with severe head trauma after a road accident and describe the beneficial effects that increasing arterial blood pressure had on the cerebral perfusion pressure, cerebral blood flow and jugular b...

journal_title：Intensive care medicine

authors： Ferring M,Berré J,Vincent JL

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVES:(1) To demonstrate that metabolic parameters are better indicators of tissue hypoxia than regional and whole oxygen consumption (VO(2)). (2) To compare intramucosal pH (pHi) in different gastrointestinal segments. DESIGN:Prospective, interventional study. SETTING:Research laboratory at a university center....

journal_title：Intensive care medicine

authors： Dubin A,Estenssoro E,Murias G,Canales H,Sottile P,Badie J,Barán M,Pálizas F,Laporte M,Rivas Díaz M

更新日期：2001-12-01 00:00:00

abstract：PURPOSE:Protective mechanical ventilation based on multiple ventilator parameters such as tidal volume, plateau pressure, and driving pressure has been widely used in acute respiratory distress syndrome (ARDS). More recently, mechanical power (MP) was found to be associated with mortality. The study aimed to investigat...

journal_title：Intensive care medicine

authors： Zhang Z,Zheng B,Liu N,Ge H,Hong Y

更新日期：2019-06-01 00:00:00